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K. Aughton · SciRah

Researcher profile · Semantic Scholar

K. Aughton

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K. Aughton — researcher profile on SciRah

h-index: 11
Works: 30
Citations: 555

Most-cited papers

In vitro and in vivo characterization of PF‐04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist
K. Af Forselles, J. Root, T. Clarke, D. Davey +3 more
2011British Journal of Pharmacology149 citations Open access
Semantic Scholar
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma.
P. Lovat, S. Oliverio, M. Ranalli, Marco Corazzari +9 more
2002Cancer Research91 citations
Semantic Scholar
Cardiac hypertrophy in mice expressing unphosphorylatable phospholemman
A. Boguslavskyi, D. Pavlovic, K. Aughton, James E. Clark +3 more
2014Cardiovascular Research55 citations Open access
Semantic Scholar
Nitric oxide regulates cardiac intracellular Na+ and Ca2 + by modulating Na/K ATPase via PKCε and phospholemman-dependent mechanism
D. Pavlovic, A. R. Hall, E. Kennington, K. Aughton +5 more
2013Journal of Molecular and Cellular Cardiology52 citations Open access
Semantic Scholar
A Separate Pool of Cardiac Phospholemman That Does Not Regulate or Associate with the Sodium Pump
K. Wypijewski, J. Howie, L. Reilly, L. Tulloch +5 more
2013Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Characterization of Uveal Melanoma Cell Lines and Primary Tumor Samples in 3D Culture
K. Aughton, H. Shahidipour, L. Djirackor, S. Coupland +1 more
2020Translational Vision Science & Technology32 citations Open access
Semantic Scholar
Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na]i
T. Eykyn, D. Aksentijević, K. Aughton, R. Southworth +2 more
2015Journal of Molecular and Cellular Cardiology31 citations Open access
Semantic Scholar
Expression of dihydropyrimidine dehydrogenase (DPD) and hENT1 predicts survival in pancreatic cancer
Nils Elander, K. Aughton, P. Ghaneh, J. Neoptolemos +23 more
2018British Journal of Cancer29 citations Open access
Semantic Scholar
MicroRNAs and Uveal Melanoma: Understanding the Diverse Role of These Small Molecular Regulators
K. Aughton, H. Kalirai, S. Coupland
2020International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
Glutathione-dependent depalmitoylation of phospholemman by peroxiredoxin 6.
J. Howie, Lindsay B. Tulloch, E. Brown, L. Reilly +8 more
2024Cell Reports13 citations Open access
Semantic Scholar
hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA
K. Aughton, Nils Elander, A. Evans, R. Jackson +22 more
2021Cancers12 citations Open access
Semantic Scholar
Intratumoural expression of deoxycytidylate deaminase or ribonuceotide reductase subunit M1 expression are not related to survival in patients with resected pancreatic cancer given adjuvant chemotherapy
Nils Elander, K. Aughton, P. Ghaneh, J. Neoptolemos +23 more
2018British Journal of Cancer10 citations Open access
Semantic Scholar
Using the Chick Embryo Model to Examine the Effects of Hypoxia Pre-conditioning of Uveal Melanoma Cells on Tumor Growth and Metastasis
J. Draper, Jodi Alexander, Rohini M. Nair, Nicole Scullion +6 more
2022Current Eye Research8 citations Open access
Semantic Scholar
Mutant K-Ras in Pancreatic Cancer: An Insight on the Role of Wild-Type N-Ras and K-Ras-Dependent Cell Cycle Regulation
Robert Ferguson, K. Aughton, A. Evans, V. Shaw +5 more
2023Current Issues in Molecular Biology5 citations Open access
Semantic Scholar
Revealing the structural microenvironment of high metastatic risk uveal melanomas following decellularisation
K. Aughton, J. Hattersley, Sarah E. Coupland, H. Kalirai
2024Scientific Reports3 citations Open access
Semantic Scholar
Unpacking the genetic etiology of uveal melanoma
S. Thornton, H. Kalirai, K. Aughton, S. Coupland
20203 citations
Semantic Scholar
Understanding and Exacerbating the Biological Response of Uveal Melanoma to Proton Beam Therapy
Laura Hawkins, H. Kalirai, K. Aughton, Rumana N. Hussain +2 more
2025Cancers2 citations Open access
Semantic Scholar
Investigating the Role of DUSP4 in Uveal Melanoma
K. Aughton, Dorota Sabat-Pośpiech, Samantha Barlow, S. Coupland +1 more
2022Translational Vision Science & Technology2 citations Open access
Semantic Scholar
Multiple quantum ﬁ ltered 23 Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum ﬁ ltered signals correlates with [Na] i of Molecular and Cellular Cardiology
Dunja Aksentijevi, K. Aughton, R. Southworth, W. Fuller +1 more
20151 citations
Semantic Scholar
GADD 153 and 12-Lipoxygenase Mediate Fenretinide-induced Apoptosis of Neuroblastoma 1
P. Lovat, S. Oliverio, M. Ranalli, Marco Corazzari +9 more
20021 citations
Semantic Scholar
Transformation of the Extracellular Matrix During Uveal Melanoma Development, Progression, and at the Hepatic Metastatic Niche.
J. Hattersley, K. Aughton, Sarah E. Coupland, H. Kalirai
2026Progress in retinal and eye research0 citations Open access
Semantic Scholar
Inhibition of ATM, ATR and DNA-PK radiosensitises 3D uveal melanoma models to X-rays and proton beam therapy
Laura Hawkins, R. Morris, H. Kalirai, K. Aughton +3 more
2026Frontiers in Oncology0 citations Open access
Semantic Scholar
K-Ras independence due to N-Ras expression in cancer cell lines giving resistance to K-Ras specific inhibitors
Robert Ferguson, K. Aughton, A. Evans, V. Shaw +2 more
2023Pancreatology (Print)0 citations
Semantic Scholar
Development of Novel Therapeutic Response Biomarkers
Nils Elander, K. Aughton, W. Greenhalf
20170 citations
Semantic Scholar
Combined analysis of cytidine deaminase mRNA transcript expression with hENT1 protein expression on tissue microarrays from the ESPAC-3 trial helps predict patient survival with gemcitabine treatment
K. Aughton, Nils Elander, D. Palmer, T. Cox +10 more
20160 citations
Semantic Scholar
Identification of novel signalling pathways dysregulated in pancreatic cancer-associated fibroblasts
Lawrence N. Barrera, B. Lane, S. Brumskill, F. Oldfield +15 more
20160 citations
Semantic Scholar
University of Birmingham Cardiac hypertrophy in mice expressing unphosphorylatable phospholemman
A. Boguslavskyi, D. Pavlovic, K. Aughton, James E. Clark +3 more
20140 citations
Semantic Scholar
University of Birmingham Nitric oxide regulates cardiac intracellular Na and Ca² by modulating Na/K ATPase via PKC and phospholemman-dependent mechanism
A. R. Hall, E. Kennington, K. Aughton, A. Boguslavskyi +4 more
20130 citations
Semantic Scholar
Phenotypic characterisation of the PLM3SA mouse expressing unphosphorylatable phospholemman
K. Aughton
20130 citations
Semantic Scholar
Abstract 15890: Reduced Na/K Pump Current, Enhanced Contractility and Negative Force-frequency Relationship in Cardiomyocytes and Hearts Isolated from Mice Expressing Unphosphorylatable Phospholemman
K. Aughton, A. R. Hall, W. Fuller, M. Shattock
20100 citations
Semantic Scholar

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