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Francesca Bufalieri · SciRah

Researcher profile · Semantic Scholar

Francesca Bufalieri

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Francesca Bufalieri — researcher profile on SciRah

h-index: 14
Works: 32
Citations: 664

Most-cited papers

Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
S. Coni, A. Mancuso, L. Di Magno, Giulia Sdruscia +15 more
2017Scientific Reports67 citations Open access
Semantic Scholar
The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I
Francesca Bufalieri, Miriam Caimano, Ludovica Lospinoso Severini, Irene Basili +9 more
2020Cancers57 citations Open access
Semantic Scholar
Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
S. Coni, A. Mancuso, L. Di Magno, Giulia Sdruscia +15 more
2017Scientific Reports57 citations Open access
Semantic Scholar
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
P. Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri +19 more
2018Nature Communications55 citations Open access
Semantic Scholar
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
Ludovica Lospinoso Severini, F. Ghirga, Francesca Bufalieri, D. Quaglio +2 more
2020Expert opinion on therapeutic targets52 citations Open access
Semantic Scholar
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Francesca Bufalieri, P. Infante, Flavia Bernardi, Miriam Caimano +23 more
2019Nature Communications49 citations Open access
Semantic Scholar
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
S. Coni, Rosa Bordone, D. Ivy, Zuleyha Nihan Yurtsever +12 more
2023Cancer Letters48 citations Open access
Semantic Scholar
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth
Ludovica Lospinoso Severini, D. Quaglio, Irene Basili, F. Ghirga +11 more
2019Cancers48 citations Open access
Semantic Scholar
Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway
R. Quaranta, M. Pelullo, Sabrina Zema, F. Nardozza +10 more
2017Cell Death and Disease40 citations Open access
Semantic Scholar
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of hedgehog-dependent medulloblastoma.
P. Infante, Alessio Malfanti, D. Quaglio, Silvia Balducci +16 more
2020Cancer Letters33 citations Open access
Semantic Scholar
Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch
P. Infante, Ludovica Lospinoso Severini, Flavia Bernardi, Francesca Bufalieri +1 more
2019Cells26 citations Open access
Semantic Scholar
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?
Ludovica Lospinoso Severini, Francesca Bufalieri, P. Infante, L. Di Marcotullio
2022Frontiers in Cell and Developmental Biology20 citations Open access
Semantic Scholar
DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer
Francesca Bufalieri, Ludovica Lospinoso Severini, Miriam Caimano, P. Infante +1 more
2020Cancers20 citations Open access
Semantic Scholar
An High-Throughput In Vivo Screening System to Select H3K4-Specific Histone Demethylase Inhibitors
C. Mannironi, M. Proietto, Francesca Bufalieri, E. Cundari +8 more
2014PLoS ONE16 citations Open access
Semantic Scholar
Dual SMO/BRAF Inhibition by Flavonolignans from Silybum marianum
Antonia Diukendjieva, M. Zaharieva, M. Mori, P. Alov +10 more
2020Antioxidants14 citations Open access
Semantic Scholar
SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma
Ludovica Lospinoso Severini, Elena Loricchio, Shirin Navacci, Irene Basili +17 more
2023Cell Death and Differentiation12 citations Open access
Semantic Scholar
MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation
Rosa Bordone, D. Ivy, Rodrigo D’Amico, Martina Barba +13 more
2024Oncogene11 citations
Semantic Scholar
Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis
Francesca Bufalieri, Irene Basili, L. Di Marcotullio, P. Infante
2021Frontiers in Molecular Neuroscience9 citations Open access
Semantic Scholar
SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation
Fabio Bordin, G. Terriaca, Adriano Apostolico, A. Di Fiore +11 more
2024Cell Death Discovery6 citations Open access
Semantic Scholar
The transcriptional response of mammalian cancer cells to irradiation is dominated by a cell cycle signature which is strongly attenuated in non-cancer cells and tissues
Francesca Bufalieri, V. Licursi, M. D'Antonio, T. Castrignanò +2 more
2012International Journal of Radiation Biology6 citations Open access
Semantic Scholar
ERAP1 as an emerging therapeutic target for medulloblastoma.
Francesca Bufalieri, D. Fruci, L. Di Marcotullio
2021Trends in Cancer4 citations
Semantic Scholar
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
Marialaura Petroni, F. Fabretti, S. Di Giulio, Vittoria Nicolis di Robilant +13 more
2022Neuropathology and Applied Neurobiology3 citations Open access
Semantic Scholar
β-Arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
P. Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri +19 more
3 citations
Semantic Scholar
MDB-57. PROTEOMIC ANALYSIS REVEALS AMBRA1 AS A NEW CRL3REN/KCTD11 SUBSTRATE PROMOTING SONIC HEDGEHOG-DEPENDENT MEDULLOBLASTOMA
Irene Basili, P. Infante, Marilisa Conenna, Flavia Bernardi +11 more
2024Neuro-Oncology2 citations Open access
Semantic Scholar
General features of the transcriptional response of mammalian cells to low- and high-LET irradiation
N. Giusti, Francesca Bufalieri, V. Licursi, T. Castrignanò +3 more
2014RENDICONTI LINCEI2 citations Open access
Semantic Scholar
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.
Irene Basili, Francesca Bufalieri, Marilisa Conenna, Shirin Navacci +33 more
2026Developmental Cell1 citations Open access
Semantic Scholar
Discovery of a new selective Endoplasmic Reticulum Aminopeptidase 1 inhibitor for Hedgehog-dependent cancers treatment.
Francesca Bufalieri, Antonino Cucinotta, Silvia Cammarone, F. Agnoli +26 more
2025Molecular Therapy1 citations Open access
Semantic Scholar
MEX3A is a diagnostic, independent prognostic biomarker and a promising therapeutic target in glioblastoma
Francesca Bufalieri, D. Armocida, Antonino Cucinotta, Pietro Familiari +12 more
2025Frontiers in Oncology1 citations Open access
Semantic Scholar
MDB-28. THE CYTOSKELETON REGULATORS FORMINS CONTROL THE SHH PATHWAY AND ARE INVOLVED IN MEDULLOBLASTOMA TUMORIGENESIS
P. Infante, Marilisa Conenna, Gennaro Adabbo, Francesca Bufalieri +4 more
2024Neuro-Oncology1 citations Open access
Semantic Scholar
Functional and therapeutic effects of Glabrescione B delivery by liposomes on Hedgehog-dependent tumors
P. Infante, Raffaella Daniele, Marta Bottero, M. Longo +18 more
2025Drug Delivery and Translational Research0 citations Open access
Semantic Scholar
MDB-29. SALL4 IS A CRL3REN/KCTD11 SUBSTRATE THAT DRIVES SONIC HEDGEHOG-DEPENDENT MEDULLOBLASTOMA
Ludovica Lospinoso Severini, Elena Loricchio, Shirin Navacci, Irene Basili +17 more
2024Neuro-Oncology0 citations Open access
Semantic Scholar
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
P. Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri +19 more
2018Nature Communications0 citations Open access
Semantic Scholar

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Flavia Bernardi×9

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Marella Maroder×8

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