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Wee Han Ang · SciRah

Researcher profile · Semantic Scholar

Wee Han Ang

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Wee Han Ang — researcher profile on SciRah

h-index: 48
Works: 129
Citations: 7,394

Most-cited papers

Carbon nanotubes for delivery of small molecule drugs.
Bin-Sheng Wong, S. Yoong, A. Jagusiak, T. Pańczyk +3 more
2013Advanced Drug Delivery Reviews528 citations Open access
Semantic Scholar
Organometallic ruthenium-based antitumor compounds with novel modes of action
Wee Han Ang, A. Casini, G. Sava, P. Dyson
2011349 citations Open access
Semantic Scholar
Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity
Z. Adhireksan, G. Davey, P. Campomanes, M. Groessl +9 more
2014Nature Communications267 citations Open access
Semantic Scholar
Ruthenium porphyrin compounds for photodynamic therapy of cancer.
F. Schmitt, P. Govindaswamy, G. Süss-Fink, Wee Han Ang +3 more
2008Journal of Medicinal Chemistry232 citations Open access
Semantic Scholar
Rational design of an organometallic glutathione transferase inhibitor.
Wee Han Ang, L. Parker, A. De Luca, L. Juillerat-Jeanneret +4 more
2009Angewandte Chemie167 citations Open access
Semantic Scholar
Induction of immunogenic cell death by chemotherapeutic platinum complexes.
Daniel Yuan Qiang Wong, W. Ong, Wee Han Ang
2015Angewandte Chemie148 citations
Semantic Scholar
Discovery and investigation of anticancer ruthenium-arene Schiff-base complexes via water-promoted combinatorial three-component assembly.
Mun Juinn Chow, C. Licona, Daniel Yuan Qiang Wong, G. Pastorin +2 more
2014Journal of Medicinal Chemistry131 citations
Semantic Scholar
Ferrocenoyl pyridine arene ruthenium complexes with anticancer properties: synthesis, structure, electrochemistry, and cytotoxicity.
Mathieu Auzias, B. Therrien, G. Süss-Fink, P. Štěpnička +2 more
2008Inorganic Chemistry123 citations Open access
Semantic Scholar
Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin.
S. Yoong, Bin-Sheng Wong, Qi-Lin Zhou, C. Chin +6 more
2014Biomaterials108 citations
Semantic Scholar
Immuno-chemotherapeutic platinum(IV) prodrugs of cisplatin as multimodal anticancer agents.
Daniel Yuan Qiang Wong, Charmian Hui Fang Yeo, Wee Han Ang
2014Angewandte Chemie104 citations
Semantic Scholar
Transcription Inhibition by Platinum DNA Cross-links in Live Mammalian Cells
Wee Han Ang, MyatNoeZin Myint, S. Lippard
2010Journal of the American Chemical Society96 citations Open access
Semantic Scholar
Tuning the activity of platinum(IV) anticancer complexes through asymmetric acylation.
C. Chin, Quan Tian, M. I. Setyawati, W. Fang +3 more
2012Journal of Medicinal Chemistry92 citations
Semantic Scholar
PlatinER: a Highly Potent Anticancer Platinum(II) Complex that induces Endoplasmic Reticulum Stress-driven Immunogenic Cell Death.
Max Jing Rui Tham, Maria V. Babak, Wee Han Ang
2020Angewandte Chemie91 citations
Semantic Scholar
Platinum(IV) prodrugs entrapped within multiwalled carbon nanotubes: Selective release by chemical reduction and hydrophobicity reversal
Jian Li, S. Yap, C. Chin, Quan Tian +3 more
201287 citations
Semantic Scholar
A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1
A. De Luca, L. Parker, Wee Han Ang, C. Rodolfo +9 more
2019Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Dual-Targeting Dual-Action Platinum(IV) Platform for Enhanced Anticancer Activity and Reduced Nephrotoxicity.
Maria V. Babak, Zhi Yang, B. Czarny, T. Toh +5 more
2019Angewandte Chemie81 citations Open access
Semantic Scholar
Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
L. Parker, L. Italiano, C. Morton, N. Hancock +10 more
2011Chemistry75 citations Open access
Semantic Scholar
Copper(ii) thiosemicarbazone complexes induce marked ROS accumulation and promote nrf2-mediated antioxidant response in highly resistant breast cancer cells.
A. Sirbu, O. Palamarciuc, Maria V. Babak, J. Lim +7 more
2017Dalton Transactions74 citations Open access
Semantic Scholar
Anticancer platinum (IV) prodrugs with novel modes of activity.
C. Chin, Daniel Yuan Qiang Wong, R. Jothibasu, Wee Han Ang
2011Current Topics in Medicinal Chemistry68 citations
Semantic Scholar
In vivo biodistribution of platinum-based drugs encapsulated into multi-walled carbon nanotubes.
Jian Li, Aakansha Pant, C. Chin, Wee Han Ang +7 more
2014Nanomedicine : nanotechnology, biology, and medicine67 citations
Semantic Scholar
Monofunctional Platinum-DNA Adducts are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
G. Zhu, MyatNoeZin Myint, Wee Han Ang, Li-Na Song +1 more
2011Cancer Research64 citations Open access
Semantic Scholar
Synthesis of new aminophosphine complexes and their catalytic activities in C–C coupling reactions
N. Bırıcık, F. Durap, Cezmi Kayan, B. Gümgüm +5 more
200861 citations Open access
Semantic Scholar
A Ratiometric Fluorescent Probe for Cisplatin: Investigating the Intracellular Reduction of Platinum(IV) Prodrug Complexes.
Xiang-Ong Jun, C. S. Lim, Hai Van Le, Wee Han Ang
2018Angewandte Chemie60 citations
Semantic Scholar
Advances in nanomaterials and their applications in point of care (POC) devices for the diagnosis of infectious diseases
D. T. N. Tram, Hao Wang, S. Sugiarto, Tao Li +3 more
2016Biotechnology Advances60 citations Open access
Semantic Scholar
Ratiometric delivery of cisplatin and doxorubicin using tumour-targeting carbon-nanotubes entrapping platinum(IV) prodrugs
C. Chin, S. Yap, Jian Li, G. Pastorin +1 more
201460 citations
Semantic Scholar
Interfering with Metabolic Profile of Triple-Negative Breast Cancer using Rationally-Designed Metformin Prodrugs.
Maria V. Babak, Kai-Ren Chong, P. Rapta, M. Zannikou +11 more
2021Angewandte Chemie55 citations
Semantic Scholar
Molecular Dynamics Study of Cisplatin Release from Carbon Nanotubes Capped by Magnetic Nanoparticles
T. Pańczyk, A. Jagusiak, G. Pastorin, Wee Han Ang +1 more
201354 citations Open access
Semantic Scholar
Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds.
A. Nazarov, Julie Risse, Wee Han Ang, F. Schmitt +7 more
2012Inorganic Chemistry52 citations Open access
Semantic Scholar
Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity
Nora Graf, Wee Han Ang, G. Zhu, MyatNoeZin Myint +1 more
2011ChemBioChem52 citations Open access
Semantic Scholar
Structural Determinants of p53-Independence in Anticancer Ruthenium-Arene Schiff-Base Complexes.
Mun Juinn Chow, Maria V. Babak, Daniel Yuan Qiang Wong, G. Pastorin +2 more
2016Molecular Pharmaceutics50 citations Open access
Semantic Scholar
Carbon nanotube bottles for incorporation, release and enhanced cytotoxic effect of cisplatin
Jian Li, S. Yap, S. Yoong, T. R. Nayak +8 more
2011Carbon50 citations Open access
Semantic Scholar
PIPAC-OX: A Phase I Study of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy in Patients with Peritoneal Metastases
Guowei Kim, Lyn Tan, R. Sundar, B. Lieske +9 more
2020Clinical Cancer Research48 citations Open access
Semantic Scholar
Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance.
K. Johansson, Mika Ito, C. Schophuizen, Sherin Mathew Thengumtharayil +11 more
2011Molecular Pharmaceutics48 citations Open access
Semantic Scholar
Finely Tuned Asymmetric Platinum(IV) Anticancer Complexes: Structure–Activity Relationship and Application as Orally Available Prodrugs
S. Yap, C. Chin, Agnes Hwee Hong Thng, Yi-Ling Pang +2 more
2017ChemMedChem46 citations
Semantic Scholar
A Crystallographic Story of Snakes and Ladders: Encapsulated Water Polymers and Rigid Metal Complexes Based on Mono-N-substituted Carboxylate 4,4′-Bipyridine
Andrew D. Phillips, Zhao-Fu Fei, Wee Han Ang, R. Scopelliti +1 more
200943 citations Open access
Semantic Scholar
Rational design of selective organoruthenium inhibitors of protein tyrosine phosphatase 1B.
Xiang-Ong Jun, C. Yap, Wee Han Ang
2012Inorganic Chemistry42 citations
Semantic Scholar
Diameter-dependent release of a cisplatin pro-drug from small and large functionalized carbon nanotubes.
Laura Muzi, C. Ménard-Moyon, J. Russier, Jian Li +5 more
2015Nanoscale41 citations Open access
Semantic Scholar
A fluorescent probe for investigating the activation of anticancer platinum(IV) prodrugs based on the cisplatin scaffold.
D. Montagner, S. Yap, Wee Han Ang
2013Angewandte Chemie40 citations Open access
Semantic Scholar
Harnessing chemoselective imine ligation for tethering bioactive molecules to platinum(IV) prodrugs.
Daniel Yuan Qiang Wong, Jia-Yi Lau, Wee Han Ang
2012Dalton Transactions40 citations
Semantic Scholar
Development of an Efficient Dual‐Action GST‐Inhibiting Anticancer Platinum(IV) Prodrug
Keefe Guang Zhi Lee, Maria V. Babak, Andrea Weiss, P. Dyson +3 more
2018ChemMedChem36 citations Open access
Semantic Scholar
Induction of the Endoplasmic Reticulum Stress Pathway by Highly Cytotoxic Organoruthenium Schiff-Base Complexes.
Mun Juinn Chow, Maria V. Babak, Kwan-Wei Tan, M. Cheong +3 more
2018Molecular Pharmaceutics34 citations
Semantic Scholar
NO Releasing and Anticancer Properties of Octahedral Ruthenium-Nitrosyl Complexes with Equatorial 1 H-Indazole Ligands.
E. Orłowska, Maria V. Babak, Orsolya Dömötör, E. A. Enyedy +12 more
2018Inorganic Chemistry32 citations Open access
Semantic Scholar
Predicting chemotherapeutic drug combinations through gene network profiling
Thi Thuy Trang Nguyen, J. Chua, K. Seah, S. Koo +10 more
2016Scientific Reports27 citations Open access
Semantic Scholar
Organometallic complexes that interconvert between trimeric and monomeric structures as a function of pH and their effect on human cancer and fibroblast cells
Wee Han Ang, Zacharias Grote, R. Scopelliti, L. Juillerat-Jeanneret +2 more
200927 citations Open access
Semantic Scholar
Acetal-Functionalized RAPTA Complexes for Conjugation and Labeling
Yuxi Tan, P. Dyson, Wee Han Ang
2011Figshare26 citations Open access
Semantic Scholar
An internal fluorescent probe based on anthracene to evaluate cation-anion interactions in imidazolium salts.
Zhao-Fu Fei, Dun-Ru Zhu, Xue Yang, Ling-Jie Meng +5 more
2010Chemistry26 citations Open access
Semantic Scholar
Harnessing Transition Metal Scaffolds for Targeted Antibacterial Therapy.
Cheng Weng, Y. Tan, Wayne Gareth Koh, Wee Han Ang
2023Angewandte Chemie25 citations Open access
Semantic Scholar
A Cisplatin-Selective Fluorescent Probe for Real-Time Monitoring of Mitochondrial Platinum Accumulation in Living Cells.
Xiang-Ong Jun, Hai Van Le, Violet Eng Yee Lee, Wee Han Ang
2020Angewandte Chemie24 citations
Semantic Scholar
Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents
E. Y. D. Chua, G. Davey, C. Chin, P. Dröge +2 more
2015Nucleic Acids Research24 citations Open access
Semantic Scholar
Targeted Antibacterial Strategy Based on Reactive Oxygen Species Generated from Dioxygen Reduction Using an Organoruthenium Complex
Cheng Weng, Linghui Shen, Jing-Wei Teo, Zhi Chiaw Lim +2 more
2021JACS Au23 citations Open access
Semantic Scholar

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