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W. Ouyang · SciRah

Researcher profile · Semantic Scholar

W. Ouyang

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W. Ouyang — researcher profile on SciRah

h-index: 30
Works: 91
Citations: 6,112

Most-cited papers

Inflammation, a Key Event in Cancer Development
Haitian Lu, W. Ouyang, Chuan-Shu Huang
2006Molecular Cancer Research1,103 citations
Semantic Scholar
Dominant-Activating, Germline Mutations in Phosphoinositide 3-Kinase p110δ Cause T Cell Senescence and Human Immunodeficiency
C. Lucas, H. Kuehn, Fang Zhao, Julie E. Niemela +24 more
2013Nature Immunology645 citations Open access
Semantic Scholar
Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
H. Kuehn, W. Ouyang, Bernice Lo, E. Deenick +32 more
2014Science584 citations Open access
Semantic Scholar
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
V. Facchinetti, W. Ouyang, Hua Wei, Nelyn Soto +11 more
2008EMBO Journal534 citations Open access
Semantic Scholar
Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells
W. Ouyang, Omar Beckett, Qian Ma, J. Paik +2 more
2010Nature Immunology487 citations
Semantic Scholar
Novel Foxo1–dependent transcriptional programs control Treg cell function
W. Ouyang, W. Liao, Chong T Luo, Na Yin +12 more
2012Nature405 citations Open access
Semantic Scholar
An Essential Role of the Forkhead-Box Transcription Factor Foxo1 in Control of T Cell Homeostasis and Tolerance
W. Ouyang, Omar Beckett, R. Flavell, Ming O. Li
2009Immunity316 citations Open access
Semantic Scholar
Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.
W. Ouyang, Omar Beckett, Qian Ma, Ming O. Li
2010Immunity248 citations Open access
Semantic Scholar
The Transcription Factor Foxo1 Controls Central Memory CD8+ T Cell Responses to Infection
Myoungjoo V. Kim, W. Ouyang, W. Liao, Michael Q. Zhang +1 more
2013Immunity210 citations Open access
Semantic Scholar
Foxo: in command of T-lymphocyte homeostasis and tolerance
W. Ouyang, Ming O. Li
2010Trends in immunology117 citations Open access
Semantic Scholar
Essential roles of PI-3K/Akt/IKKβ/NFκB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells
W. Ouyang, Jingxia Li, Qian Ma, Chuan-Shu Huang
200691 citations
Semantic Scholar
mTOR Complex 2 Targets Akt for Proteasomal Degradation via Phosphorylation at the Hydrophobic Motif*
You-Tong Wu, W. Ouyang, A. Lazorchak, Dou Liu +2 more
2011Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation.
Jian Wang, W. Ouyang, Jingxia Li, Li-Xin Wei +5 more
2005Cancer Research79 citations Open access
Semantic Scholar
Cyclin D1 Induction through IκB Kinase β/Nuclear Factor-κB Pathway Is Responsible for Arsenite-Induced Increased Cell Cycle G1-S Phase Transition in Human Keratinocytes
W. Ouyang, Qian Ma, Jingxia Li, Dongyun Zhang +3 more
200570 citations Open access
Semantic Scholar
PI-3K/Akt Pathway-Dependent Cyclin D1 Expression Is Responsible for Arsenite-Induced Human Keratinocyte Transformation
W. Ouyang, Wen-Jing Luo, Dongyun Zhang, J. Jian +6 more
2007Environmental Health Perspectives55 citations Open access
Semantic Scholar
Effects of Mild Chronic Intermittent Cold Exposure on Rat Organs
Xiaohui Wang, Honglei Che, Wen-Bin Zhang, Jiye Wang +7 more
2015International Journal on Biological Sciences54 citations Open access
Semantic Scholar
Nickel Compounds Render Anti-apoptotic Effect to Human Bronchial Epithelial Beas-2B Cells by Induction of Cyclooxygenase-2 through an IKKβ/p65-dependent and IKKα- and p50-independent Pathway*
Jin Ding, Xinhai Zhang, Jingxia Li, Lun Song +6 more
2006Journal of Biological Chemistry50 citations Open access
Semantic Scholar
NFAT3 is specifically required for TNF-α-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
Yan Yan, Jingxia Li, W. Ouyang, Qian Ma +6 more
2006Journal of Cell Science48 citations
Semantic Scholar
Cyclin D1 induction through IkappaB kinase beta/nuclear factor-kappaB pathway is responsible for arsenite-induced increased cell cycle G1-S phase transition in human keratinocytes.
W. Ouyang, Qian Ma, Jingxia Li, Dongyun Zhang +3 more
2005Cancer Research48 citations
Semantic Scholar
Essential roles of PI-3K/Akt/IKKbeta/NFkappaB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells.
W. Ouyang, Jingxia Li, Qian Ma, Chuan-Shu Huang
2006Carcinogenesis47 citations
Semantic Scholar
p85α Acts as a Novel Signal Transducer for Mediation of Cellular Apoptotic Response to UV Radiation
Lun Song, Jingxia Li, Jianping Ye, Gang Yu +6 more
2007Molecular and Cellular Biology42 citations Open access
Semantic Scholar
Generation of monoclonal antibodies to cancer/testis (CT) antigen CT10/MAGE-C2.
R. Zhuang, Yong Zhu, Liang Fang, Xue-Song Liu +13 more
2006Cancer Immunity42 citations
Semantic Scholar
TGF-β Cytokine Signaling Promotes CD8+ T Cell Development and Low-affinity CD4+ T Cell Homeostasis by Regulation of Interleukin-7 Receptor-α Expression
W. Ouyang, Soyoung A Oh, Qian Ma, Michael Bivona +2 more
2013Immunity41 citations Open access
Semantic Scholar
Cyclooxygenase-2 Induction by Arsenite Is through a Nuclear Factor of Activated T-cell-dependent Pathway and Plays an Antiapoptotic Role in Beas-2B Cells*
Jin Ding, Jingxia Li, Caifang Xue, Kang-Jian Wu +4 more
2006Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Establishment of an ELISA system for determining soluble LAIR-1 levels in sera of patients with HFRS and kidney transplant.
W. Ouyang, Jiang-Nan Xue, Jing-Mei Liu, W. Jia +8 more
2004JIM - Journal of Immunological Methods37 citations
Semantic Scholar
The COX-2 Induction by Arsenite is Through NFAT-Dependent Pathway And Plays Anti-apoptotic Role in Beas-2B cell*
Jin Ding, Jingxia Li, Caifang Xue, Kang-Jian Wu +4 more
200634 citations
Semantic Scholar
Dysregulation of Akt-FOXO1 Pathway Leads to Dysfunction of Regulatory T Cells in Patients with Psoriasis.
Bing Li, Jie Lei, Lu-Ting Yang, Chao Gao +11 more
2019Journal of Investigative Dermatology33 citations Open access
Semantic Scholar
Benzo[a]pyrene diol‐epoxide (B[a]PDE) upregulates COX‐2 expression through MAPKs/AP‐1 and IKKβ/NF‐κB in mouse epidermal Cl41 cells
W. Ouyang, Qian Ma, Jingxia Li, Dongyun Zhang +4 more
200732 citations
Semantic Scholar
9.1C3 is identical to LAIR-1, which is expressed on hematopoietic progenitors.
W. Ouyang, D. Ma, Di Lin, Ying-Hui Sun +6 more
2003Biochemical and Biophysical Research Communications - BBRC31 citations
Semantic Scholar
Effects of Polycyclic Aromatic Hydrocarbons (PAHs) on Vascular Endothelial Growth Factor Induction through Phosphatidylinositol 3-Kinase/AP-1-dependent, HIF-1α-independent Pathway*
Jin Ding, Jingxia Li, Jing-Yuan Chen, Haobin Chen +7 more
2006Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Epigenetic Inactivation of SOX30 Is Associated with Male Infertility and Offers a Therapy Target for Non-obstructive Azoospermia
Fei Han, Xiao Jiang, Zhi-ming Li, X. Zhuang +12 more
2019Molecular Therapy: Nucleic Acids29 citations Open access
Semantic Scholar
PI‐3K/Akt signal pathway plays a crucial role in arsenite‐induced cell proliferation of human keratinocytes through induction of cyclin D1
W. Ouyang, Jingxia Li, Dongyun Zhang, Bing-Hua Jiang +1 more
2007Journal of Cellular Biochemistry29 citations
Semantic Scholar
Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKα-dependent cyclin D1 down-regulation
W. Ouyang, Dongyun Zhang, Jingxia Li, U. Verma +2 more
2009Journal of Cellular Physiology28 citations Open access
Semantic Scholar
CD226 is expressed on the megakaryocytic lineage from hematopoietic stem cells/progenitor cells and involved in its polyploidization
D. Ma, Ying-Hui Sun, Di Lin, Haoyang Wang +7 more
2005European Journal of Haematology26 citations
Semantic Scholar
JNK1, but not JNK2, is required for COX-2 induction by nickel compounds.
Dongyun Zhang, Jingxia Li, Kang-Jian Wu, W. Ouyang +4 more
2006Carcinogenesis24 citations Open access
Semantic Scholar
Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression
W. Ouyang, Jingxia Li, Xiang-Lin Shi, Max Costa +1 more
2005Molecular and Cellular Biochemistry22 citations
Semantic Scholar
Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability
Jing-Jie Zhang, W. Ouyang, Jingxia Li, Dongyun Zhang +4 more
2012Toxicology and Applied Pharmacology21 citations Open access
Semantic Scholar
Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome.
Jing-Mei Liu, Yong Zhu, Zhu-wei Xu, W. Ouyang +8 more
2006Clinical Immunology21 citations
Semantic Scholar
Pb exposure attenuates hypersensitivity in vivo by increasing regulatory T cells.
Liang Fang, Fang Zhao, Xue-Feng Shen, W. Ouyang +6 more
2012Toxicology and Applied Pharmacology20 citations
Semantic Scholar
Activation of both nuclear factor of activated T cells and inhibitor of nuclear factor‐κB kinase β‐subunit‐/nuclear factor‐κB is critical for cyclooxygenase‐2 induction by benzo[a]pyrene in human bronchial epithelial cells
Jin Ding, Kang-Jian Wu, Dongyun Zhang, Wen-Jing Luo +4 more
200720 citations Open access
Semantic Scholar
Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells.
W. Ouyang, Yu Hu, Jingxia Li, M. Ding +8 more
2007Carcinogenesis20 citations
Semantic Scholar
A JNK1/AP-1–Dependent, COX-2 Induction Is Implicated in 12-O-Tetradecanoylphorbol-13-Acetate–Induced Cell Transformation through Regulating Cell Cycle Progression
Dongyun Zhang, Jingxia Li, Lun Song, W. Ouyang +2 more
2008Molecular Cancer Research19 citations Open access
Semantic Scholar
Variable Induction of Pro-Inflammatory Cytokines by Commercial SARS CoV-2 Spike Protein Reagents: Potential Impacts of LPS on In Vitro Modeling and Pathogenic Mechanisms In Vivo
W. Ouyang, Tao Xie, H. Fang, Chunling Gao +5 more
2021bioRxiv16 citations Open access
Semantic Scholar
Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKbeta/NF-kappaB in mouse epidermal Cl41 cells.
W. Ouyang, Qian Ma, Jingxia Li, Dongyun Zhang +4 more
2007Molecular Carcinogenesis16 citations
Semantic Scholar
Identification and Characterization of the CD226 Gene Promoter*
Jin-long Jian, Can-sheng Zhu, Zhu-wei Xu, W. Ouyang +5 more
2006Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates
W. Ouyang, Peng-Fei Guo, Kazuyo Takeda, Qiong Fu +2 more
2020Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
A New Murine Model for Gastrointestinal Anthrax Infection
Tao Xie, Chen-Kun Sun, K. Uslu, Roger D. Auth +3 more
2013PLoS ONE13 citations Open access
Semantic Scholar
Anthrax Lethal Toxin Inhibits Translation of Hypoxia-inducible Factor 1α and Causes Decreased Tolerance to Hypoxic Stress*
W. Ouyang, C. Torigoe, H. Fang, Tao Xie +1 more
2013Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Cyclooxygenase-2 (COX-2) Mediates Arsenite Inhibition of UVB-Induced Cellular Apoptosis in Mouse Epidermal Cl41 Cells
Z. Zuo, W. Ouyang, J. Li, M. Costa +1 more
2012Current Cancer Drug Targets12 citations Open access
Semantic Scholar
Identification of SRY‐box 30 as an age‐related essential gatekeeper for male germ‐cell meiosis and differentiation
Fei Han, Li Yin, Xiao Jiang, Xi Zhang +12 more
2021Aging Cell11 citations Open access
Semantic Scholar

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