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S. Vacher · SciRah

Researcher profile · Semantic Scholar

S. Vacher

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S. Vacher — researcher profile on SciRah

h-index: 50
Works: 232
Citations: 7,309

Most-cited papers

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers
F. Coussy, R. El-Botty, S. Chateau-Joubert, A. Dahmani +30 more
2020Science Translational Medicine121 citations Open access
Semantic Scholar
Prognostic value of intratumoral Fusobacterium nucleatum and association with immune-related gene expression in oral squamous cell carcinoma patients
C. Neuzillet, M. Marchais, S. Vacher, M. Hilmi +17 more
2021Scientific Reports112 citations Open access
Semantic Scholar
PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance
E. Montaudon, J. Nikitorowicz-Buniak, L. Sourd, L. Morisset +34 more
2020Nature Communications106 citations Open access
Semantic Scholar
Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
R. El-Botty, L. Morriset, E. Montaudon, Zakia Tariq +23 more
2023Nature Communications98 citations Open access
Semantic Scholar
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
M. Kamal, S. Lameiras, Marc Deloger, A. Morel +19 more
2020British Journal of Cancer82 citations Open access
Semantic Scholar
Cortical branched actin determines cell cycle progression
Nicolas Molinie, S. N. Rubtsova, A. Fokin, S. Visweshwaran +10 more
2019Cell Research82 citations Open access
Semantic Scholar
Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts
F. Coussy, M. Lavigne, L. de Koning, R. El Botty +18 more
2020Theranostics58 citations Open access
Semantic Scholar
Nivolumab plus chemoradiotherapy in locally-advanced cervical cancer: the NICOL phase 1 trial
M. Rodrigues, Giulia Vanoni, P. Loap, C. Dubot +24 more
2023Nature Communications56 citations Open access
Semantic Scholar
Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers
F. Coussy, R. El Botty, M. Lavigne, C. Gu +16 more
2020Journal of Hematology & Oncology55 citations Open access
Semantic Scholar
Phase II study of intrathecal administration of trastuzumab in patients with HER2-positive breast cancer with leptomeningeal metastasis.
Florence Oberkampf, M. Gutiérrez, Olfa Trabelsi Grati, É. Le Rhun +7 more
2022Neuro-Oncology54 citations Open access
Semantic Scholar
A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer
F. Coussy, L. Koning, M. Lavigne, V. Bernard +26 more
2019International Journal of Cancer52 citations Open access
Semantic Scholar
Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma
C. Neuzillet, R. Nicolle, J. Raffenne, A. Tijeras-Raballand +15 more
2022Journal of Pathology47 citations Open access
Semantic Scholar
ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin
Iris Tanaka, Alina Chakraborty, O. Saulnier, Clara Benoit-Pilven +9 more
2020Nucleic Acids Research47 citations Open access
Semantic Scholar
Intratumoral microbiome is driven by metastatic site and associated with immune histopathological parameters: An ancillary study of the SHIVA clinical trial.
M. Hilmi, M. Kamal, S. Vacher, C. Dupain +15 more
2023European Journal of Cancer41 citations Open access
Semantic Scholar
Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers
Petra ter Brugge, Sarah C. Moser, I. Bièche, P. Kristel +29 more
2023Nature Communications38 citations Open access
Semantic Scholar
BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer
M. Rouanne, J. Adam, C. Radulescu, D. Letourneur +25 more
2022Journal of Clinical Investigation36 citations Open access
Semantic Scholar
Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma
Olivia Leblanc, S. Vacher, C. Lecerf, E. Jeannot +11 more
2020Cancer Biology and Medicine35 citations Open access
Semantic Scholar
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor
M. Lacombe, F. Lamarche, O. De Wever, T. Padilla-Benavides +25 more
2021BMC Biology31 citations Open access
Semantic Scholar
Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma
Juliette Mainguené, S. Vacher, M. Kamal, A. Hamza +27 more
2022Molecular Oncology30 citations Open access
Semantic Scholar
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance
Catalina Lodillinsky, L. Fuhrmann, M. Irondelle, O. Pylypenko +14 more
2021Oncogene29 citations Open access
Semantic Scholar
Alteration of splicing factors’ expression during liver disease progression: impact on hepatocellular carcinoma outcome
Hualin Wang, Bouchra Lekbaby, N. Farès, J. Augustin +15 more
2019Hepatology International29 citations
Semantic Scholar
High Positive Correlations between ANRIL and p16-CDKN2A/p15-CDKN2B/p14-ARF Gene Cluster Overexpression in Multi-Tumor Types Suggest Deregulated Activation of an ANRIL–ARF Bidirectional Promoter
K. Drak Alsibai, S. Vacher, D. Meseure, A. Nicolas +11 more
2019Non-Coding RNA28 citations Open access
Semantic Scholar
Mechanistic Signatures of Human Papillomavirus Insertions in Anal Squamous Cell Carcinomas
A. Morel, C. Neuzillet, M. Wack, S. Lameiras +14 more
2019Cancers26 citations Open access
Semantic Scholar
P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration
Maïlys Le Borgne-Rochet, Lucie Angevin, E. Bazellières, Laura Ordas +10 more
2019Journal of Cell Science25 citations Open access
Semantic Scholar
Prognostic value of tumor mutational burden in patients with oral cavity squamous cell carcinoma treated with upfront surgery
A. Moreira, A. Poulet, J. Masliah-Planchon, C. Lecerf +24 more
2021ESMO Open24 citations Open access
Semantic Scholar
Interaction between IGF2‐PI3K axis and cancer‐associated‐fibroblasts promotes anal squamous carcinogenesis
W. Cacheux, A. Lièvre, S. Richon, S. Vacher +10 more
2019International Journal of Cancer24 citations Open access
Semantic Scholar
Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1-Mutated Human Chordoma Xenograft
T. Passeri, A. Dahmani, J. Masliah-Planchon, A. Naguez +16 more
2022Cancers21 citations Open access
Semantic Scholar
Evolution of synchronous female bilateral breast cancers and response to treatment
A. Hamy, J. Abécassis, K. Driouch, L. Darrigues +29 more
2023Nature Medicine17 citations Open access
Semantic Scholar
HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast
I. Bièche, F. Coussy, R. El-Botty, S. Vacher +12 more
2021Journal of Hematology & Oncology17 citations Open access
Semantic Scholar
Valproic Acid Decreases Endothelial Colony Forming Cells Differentiation and Induces Endothelial-to-Mesenchymal Transition-like Process
N. Névo, S. Lecourt, I. Bièche, M. Kucia +7 more
2020Stem Cell Reviews and Reports17 citations
Semantic Scholar
Assessment of prognostic implication of a panel of oncogenes in bladder cancer and identification of a 3-gene signature associated with recurrence and progression risk in non-muscle-invasive bladder cancer
C. Le Goux, S. Vacher, A. Schnitzler, Nicolas Barry Delongchamps +7 more
2020Scientific Reports17 citations Open access
Semantic Scholar
Familial uveal melanoma and other tumours in 25 families with monoallelic germline MBD4 variants.
M. Villy, Anaïs Le Ven, M. Le Mentec, J. Masliah-Planchon +19 more
2023Journal of the National Cancer Institute16 citations
Semantic Scholar
Prognostic Value of Fusobacterium nucleatum after Abdominoperineal Resection for Anal Squamous Cell Carcinoma
M. Hilmi, C. Neuzillet, J. Lefèvre, M. Svrcek +17 more
2022Cancers16 citations Open access
Semantic Scholar
Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant
Julien Jacquemetton, L. Kassem, Coralie Poulard, A. Dahmani +12 more
2021Breast Cancer Research16 citations Open access
Semantic Scholar
Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer
S. Vacher, Voreak Suybeng, E. Girard, J. Masliah-Planchon +11 more
2020Cancers16 citations Open access
Semantic Scholar
MSH3: a confirmed predisposing gene for adenomatous polyposis
M. Villy, J. Masliah-Planchon, A. Schnitzler, Hélène Delhomelle +21 more
2023Journal of Medical Genetics15 citations
Semantic Scholar
In vivo efficacy assessment of the CDK4/6 inhibitor palbociclib and the PLK1 inhibitor volasertib in human chordoma xenografts
T. Passeri, A. Dahmani, J. Masliah-Planchon, R. El Botty +10 more
2022Frontiers in Oncology15 citations Open access
Semantic Scholar
Hemoglobin overexpression and splice signature as new features of inflammatory breast cancer?
F. Lerebours, S. Vacher, J. Guinebretière, S. Rondeau +8 more
2020Journal of Advanced Research15 citations Open access
Semantic Scholar
PLEKHS1: A new molecular marker predicting risk of progression of non-muscle-invasive bladder cancer
G. Pignot, C. Le Goux, S. Vacher, A. Schnitzler +8 more
2019Oncology Letters15 citations Open access
Semantic Scholar
Deciphering molecular relapse and intra-tumor heterogeneity in non-metastatic resectable head and neck squamous cell carcinoma using circulating tumor DNA.
G. Marret, C. Lamy, S. Vacher, L. Cabel +27 more
2024Oral Oncology12 citations
Semantic Scholar
Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition.
Mallory Genest, F. Comunale, Damien Planchon, Pauline Govindin +10 more
2022Journal of Cell Science12 citations Open access
Semantic Scholar
Biopathological Significance of PIWI–piRNA Pathway Deregulation in Invasive Breast Carcinomas
D. Meseure, S. Vacher, S. Boudjemaa, M. Laé +8 more
2020Cancers12 citations Open access
Semantic Scholar
Internal validation strategy for high dimensional prognosis model: A simulation study and application to transcriptomic in head and neck tumors
A. Dubray-Vautrin, Victor Gravrand, G. Marret, C. Lamy +9 more
2025Computational and Structural Biotechnology Journal11 citations Open access
Semantic Scholar
Pathogenic alterations in PIK3CA and KMT2C are frequent and independent prognostic factors in anal squamous cell carcinoma treated with salvage abdominoperineal resection
A. Hamza, J. Masliah-Planchon, C. Neuzillet, Jérémie H. Lefèvre +22 more
2023International Journal of Cancer11 citations Open access
Semantic Scholar
Restrained activation of CYFIP2-containing WAVE complexes controls membrane protrusions and cell migration
A. Polesskaya, Arthur Boutillon, Sheng Yang, Yanan Wang +13 more
2020bioRxiv11 citations Open access
Semantic Scholar
High Expression of AhR and Environmental Pollution as AhR-Linked Ligands Impact on Oncogenic Signaling Pathways in Western Patients with Gastric Cancer—A Pilot Study
Martine Perrot-Applanat, Cynthia Pimpie, S. Vacher, Marc Pocard +1 more
2024Biomedicines9 citations Open access
Semantic Scholar
Differential Expression of Genes Involved in Metabolism and Immune Response in Diffuse and Intestinal Gastric Cancers, a Pilot Ptudy
M. Perrot-Applanat, Cynthia Pimpie, S. Vacher, I. Bièche +2 more
2022Biomedicines9 citations Open access
Semantic Scholar
Rational testing for gene fusion in colorectal cancer: MSI and RAS-BRAF wild-type metastatic colorectal cancer as target population for systematic screening.
M. Delaye, S. Ibadioune, C. Julié, C. Marin +13 more
2022European Journal of Cancer9 citations Open access
Semantic Scholar
The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis
F. Lallemand, S. Vacher, L. de Koning, Ambre Petitalot +13 more
2020Scientific Reports9 citations Open access
Semantic Scholar
HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers
R. El-Botty, S. Vacher, Juliette Mainguené, A. Briaux +16 more
2023Molecular Oncology8 citations Open access
Semantic Scholar

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