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M. Diefenbacher · SciRah

Researcher profile · Semantic Scholar

M. Diefenbacher

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M. Diefenbacher — researcher profile on SciRah

h-index: 27
Works: 48
Citations: 2,504

Most-cited papers

RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms
R. Fritsch, I. de Krijger, K. Fritsch, R. George +5 more
2013Cell308 citations Open access
Semantic Scholar
The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.
Madhu S. Kumar, D. Hancock, M. Molina-Arcas, M. Steckel +9 more
2012Cell271 citations Open access
Semantic Scholar
Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance
E. Castellano, C. Sheridan, M. Z. Thin, E. Nye +9 more
2013Cancer Cell160 citations Open access
Semantic Scholar
The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer.
M. Diefenbacher, N. Popov, Sophia M. Blake, Christina Schülein-Völk +5 more
2014Journal of Clinical Investigation154 citations Open access
Semantic Scholar
F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Rocío Sancho, A. Jandke, H. Davis, M. Diefenbacher +2 more
2010Gastroenterology124 citations
Semantic Scholar
RsfA (YbeB) Proteins Are Conserved Ribosomal Silencing Factors
R. Häuser, Markus Pech, Jaroslaw Kijek, Hiroshi Yamamoto +10 more
2012PLoS Genetics107 citations Open access
Semantic Scholar
The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling
A. Chakraborty, M. Diefenbacher, A. Mylona, O. Kassel +1 more
2015Nature Communications96 citations Open access
Semantic Scholar
A MYC/GCN2/eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
S. Schmidt, D. Gay, F. Uthe, S. Denk +26 more
2019Nature Cell Biology90 citations Open access
Semantic Scholar
Neurotrophic factor GDNF regulates intestinal barrier function in inflammatory bowel disease.
M. Meir, N. Burkard, Hanna Ungewiss, M. Diefenbacher +7 more
2019Journal of Clinical Investigation87 citations Open access
Semantic Scholar
Dual regulation of Fbw7 function and oncogenic transformation by Usp28.
Christina Schülein-Völk, E. Wolf, Jing Zhu, Wenshan Xu +7 more
2014Cell Reports86 citations Open access
Semantic Scholar
Usp28 counteracts Fbw7 in intestinal homeostasis and cancer
M. Diefenbacher, A. Chakraborty, Sophia M. Blake, R. Mitter +3 more
2015Cancer Research71 citations Open access
Semantic Scholar
LUBAC determines chemotherapy resistance in squamous cell lung cancer
E. Ruiz, M. Diefenbacher, J. Nelson, Rocío Sancho +12 more
2019Journal of Experimental Medicine69 citations Open access
Semantic Scholar
CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion
Petra Baumann, W. Thiele, N. Cremers, Santoshi Muppala +7 more
2011Cellular and Molecular Life Sciences68 citations Open access
Semantic Scholar
Myosin Va cooperates with PKA RIα to mediate maintenance of the endplate in vivo
Ira V. Röder, Kyeong-rock Choi, M. Reischl, Yvonne Petersen +4 more
2010Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Requirement for Interaction of PI3-Kinase p110 alpha with RAS in Lung Tumor Maintenance
E. Castellano, C. Sheridan, M. Z. Thin, E. Nye +9 more
201363 citations
Semantic Scholar
Restriction to Fos family members of Trip6-dependent coactivation and glucocorticoid receptor-dependent trans-repression of activator protein-1.
M. Diefenbacher, S. Sekula, Christine Heilbock, J. Maier +5 more
2008Molecular Endocrinology63 citations Open access
Semantic Scholar
Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells
Cristian Prieto-Garcia, O. Hartmann, Michaela Reissland, F. Braun +12 more
2020EMBO Molecular Medicine62 citations Open access
Semantic Scholar
Intestinal Epithelial Barrier Maturation by Enteric Glial Cells Is GDNF-Dependent
M. Meir, Felix Kannapin, M. Diefenbacher, Yalda Ghoreishi +9 more
2021International Journal of Molecular Sciences60 citations Open access
Semantic Scholar
Arginine methylation of the c‐Jun coactivator RACO‐1 is required for c‐Jun/AP‐1 activation
Clare C. Davies, A. Chakraborty, M. Diefenbacher, M. Skehel +1 more
2013EMBO Journal49 citations Open access
Semantic Scholar
USP28: Oncogene or Tumor Suppressor? A Unifying Paradigm for Squamous Cell Carcinoma
Cristian Prieto-Garcia, Ines Tomaskovic, V. J. Shah, I. Dikič +1 more
2021Cells47 citations Open access
Semantic Scholar
JunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer
E. Ruiz, Linxiang Lan, M. Diefenbacher, E. M. Riising +9 more
2021JCI Insight43 citations Open access
Semantic Scholar
c-Jun localizes to the nucleus independent of its phosphorylation by and interaction with JNK and vice versa promotes nuclear accumulation of JNK.
I. Schreck, M. Al-Rawi, J. Mingot, Christina Scholl +4 more
2011Biochemical and Biophysical Research Communications - BBRC41 citations
Semantic Scholar
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer
C. R. Maier, O. Hartmann, Cristian Prieto-Garcia, Kamal M. Al-Shami +15 more
2023Cell Death and Differentiation35 citations Open access
Semantic Scholar
Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesion
Hanna Ungewiss, Vera Rötzer, M. Meir, Christina Fey +3 more
2018Cellular and Molecular Life Sciences34 citations Open access
Semantic Scholar
Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway
Cristian Prieto-Garcia, O. Hartmann, Michaela Reissland, Thomas Fischer +8 more
2020Cell Death and Differentiation33 citations Open access
Semantic Scholar
Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance.
Catherine A. Cremona, Rocío Sancho, M. Diefenbacher, A. Behrens
2016Seminars in Cancer Biology32 citations
Semantic Scholar
Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease
O. Hartmann, Michaela Reissland, C. R. Maier, Thomas Fischer +14 more
2021Frontiers in Cell and Developmental Biology27 citations Open access
Semantic Scholar
PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy
Thomas Fischer, O. Hartmann, Michaela Reissland, Cristian Prieto-Garcia +13 more
2021Cell & Bioscience24 citations Open access
Semantic Scholar
The nuclear isoform of the LIM domain protein Trip6 integrates activating and repressing signals at the promoter-bound glucocorticoid receptor.
M. Diefenbacher, M. Litfin, P. Herrlich, O. Kassel
2010Molecular and Cellular Endocrinology20 citations
Semantic Scholar
The LIM Domain Protein nTRIP6 Recruits the Mediator Complex to AP-1-Regulated Promoters
M. Diefenbacher, D. Reich, Oliver Dahley, Denise Kemler +3 more
2014PLoS ONE19 citations Open access
Semantic Scholar
RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival
R. Novak, Yamen Abu Ahmad, M. Timaner, Eliya Bitman-Lotan +10 more
2022Cell Death and Disease17 citations Open access
Semantic Scholar
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K
Cristian Prieto-Garcia, O. Hartmann, Michaela Reissland, F. Braun +11 more
2021bioRxiv16 citations Open access
Semantic Scholar
Exploration of zebrafish larvae as an alternative whole-animal model for nephrotoxicity testing.
B. Bauer, D. Liedtke, S. Jarzina, E. Stammler +5 more
2021Toxicology Letters13 citations
Semantic Scholar
DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma
A. Strubel, Philipp Münick, O. Hartmann, Apirat Chaikuad +12 more
2023Cell Death and Disease11 citations Open access
Semantic Scholar
Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
Takashi Furusawa, Renzo Cavero, Yue Liu, Hao-Jian Li +10 more
2023bioRxiv9 citations Open access
Semantic Scholar
CIP2A regulates MYC translation (via its 5′UTR) in colorectal cancer
S. Denk, S. Schmidt, Y. Schurr, G. Schwarz +6 more
2020International Journal of Colorectal Disease9 citations Open access
Semantic Scholar
Acute systemic knockdown of Atg7 is lethal and causes pancreatic destruction in shRNA transgenic mice
Laura Mainz, Mohamed A. F. E. Sarhan, S. Roth, U. Sauer +11 more
2022Autophagy7 citations Open access
Semantic Scholar
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells
C. Otto, C. Kastner, S. Schmidt, K. Uttinger +12 more
2022Molecular Oncology7 citations Open access
Semantic Scholar
A novel feedback loop between DYRK2 and USP28 regulates cancer homeostasis and DNA damage signaling
Lucía Suanes-Cobos, Irene Aguilera-Ventura, Miguel Torres-Ramos, Alejandra Serrano-Yubero +8 more
2025Cell Death and Differentiation4 citations Open access
Semantic Scholar
Autophagy Blockage Reduces the Incidence of Pancreatic Ductal Adenocarcinoma in the Context of Mutant Trp53
Laura Mainz, Mohamed A. F. E. Sarhan, S. Roth, U. Sauer +6 more
2022Frontiers in Cell and Developmental Biology3 citations Open access
Semantic Scholar
Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling
Michaela Reissland, O. Hartmann, Saskia Tauch, Cristian Prieto-Garcia +26 more
2023bioRxiv2 citations Open access
Semantic Scholar
Pharmacological arginine deprivation renders pancreatic cancer cells susceptible to senolysis and inhibition of the integrated stress response
Laura Mainz, Mohamed A. F. E. Sarhan, Lisa Schlicker, Stefanie Kirner +12 more
2026bioRxiv0 citations Open access
Semantic Scholar
PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy
Thomas Fischer, O. Hartmann, Michaela Reissland, Cristian Prieto-Garcia +13 more
2022Cell & Bioscience0 citations Open access
Semantic Scholar
PTEN mutant NSCLC require ATM to suppress pro-apoptotic signalling and evade radiotherapy
Thomas Fischer, O. Hartmann, Michaela Reissland, Cristian Prieto-Garcia +8 more
2021bioRxiv0 citations Open access
Semantic Scholar
Evaluation of larval zebrafish as an alternative whole-animal model for nephrotoxicity testing
B. Bauer, D. Liedtke, S. Jarzina, E. Stammler +6 more
2021Toxicology Letters0 citations
Semantic Scholar
The USP28-ΔNp63 axis is a vulnerability of squamous tumours
Cristian Prieto-Garcia, O. Hartmann, Michaela Reissland, F. Braun +8 more
2019bioRxiv0 citations Open access
Semantic Scholar
Correction to: Dsg2 via Src-mediated transactivation shapes EGFR signaling towards cell adhesion
Hanna Ungewiss, Vera Rötzer, M. Meir, Christina Fey +3 more
2019Cellular and Molecular Life Sciences0 citations Open access
Semantic Scholar
The transcriptional co-activator function of the LIM-domain protein nTrip6
M. Diefenbacher
20090 citations
Semantic Scholar

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