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M. Ehrenstein · SciRah

Researcher profile · Semantic Scholar

M. Ehrenstein

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M. Ehrenstein — researcher profile on SciRah

h-index: 59
Works: 177
Citations: 17K

Most-cited papers

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation
F. Flores-Borja, A. Bosma, D. Ng, V. Reddy +3 more
2013Science Translational Medicine674 citations
Semantic Scholar
The importance of natural IgM: scavenger, protector and regulator
M. Ehrenstein, C. A. Notley
2010Nature reviews. Immunology634 citations
Semantic Scholar
Mice Lacking Endogenous IL-10–Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells
N. Carter, R. Vasconcellos, E. Rosser, C. Tulone +5 more
2011Journal of Immunology466 citations
Semantic Scholar
Human FoxP3+ regulatory T cells in systemic autoimmune diseases.
M. Miyara, G. Gorochov, M. Ehrenstein, L. Musset +2 more
2011Autoimmunity Reviews331 citations
Semantic Scholar
University of Birmingham Germinal center B cells govern their own fate via antibody feedback
Yang Zhang, M. Meyer-Hermann, Laura A. George, M. Figge +10 more
2013286 citations
Semantic Scholar
Elevated serum BAFF levels are associated with rising anti-double-stranded DNA antibody levels and disease flare following B cell depletion therapy in systemic lupus erythematosus.
L. Carter, D. Isenberg, M. Ehrenstein
2013Arthritis & Rheumatism190 citations
Semantic Scholar
Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis
D. X. Nguyen, M. Ehrenstein
2016Journal of Experimental Medicine171 citations Open access
Semantic Scholar
Th17 cells are restrained by Treg cells via the inhibition of interleukin-6 in patients with rheumatoid arthritis responding to anti-tumor necrosis factor antibody therapy.
Jenny L. McGovern, D. X. Nguyen, C. A. Notley, C. Mauri +2 more
2012Arthritis & Rheumatism162 citations
Semantic Scholar
M3C: Monte Carlo reference-based consensus clustering
C. John, David Watson, Dominic Russ, K. Goldmann +4 more
2020Scientific Reports139 citations Open access
Semantic Scholar
Circulating Plasmablasts Induce The Differentiation of Human T Follicular Helper Cells via IL-6 production
K. Chavele, E. Merry, M. Ehrenstein
2015Journal of Immunology124 citations Open access
Semantic Scholar
Effectiveness of Belimumab After Rituximab in Systemic Lupus Erythematosus
M. Shipa, A. Embleton-Thirsk, M. Parvaz, L. Santos +6 more
2021Annals of Internal Medicine122 citations Open access
Semantic Scholar
Regulatory T‐cells in systemic lupus erythematosus and rheumatoid arthritis
K. Chavele, M. Ehrenstein
2011FEBS Letters121 citations Open access
Semantic Scholar
Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells
C. A. Notley, Mark A. Brown, G. Wright, M. Ehrenstein
2011Journal of Immunology119 citations Open access
Semantic Scholar
The BAFFling effects of rituximab in lupus: danger ahead?
M. Ehrenstein, C. Wing
2016Nature Reviews Rheumatology118 citations
Semantic Scholar
The efficacy of repeated treatment with B-cell depletion therapy in systemic lupus erythematosus: an evaluation.
T. Turner-Stokes, T. Lu, M. Ehrenstein, I. Giles +2 more
2011Rheumatology85 citations
Semantic Scholar
B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels
M. Lazarus, T. Turner-Stokes, K. Chavele, D. Isenberg +1 more
2012Rheumatology78 citations Open access
Semantic Scholar
The impact of biological therapy on regulatory T cells in rheumatoid arthritis.
R. Byng-Maddick, M. Ehrenstein
2015Rheumatology74 citations Open access
Semantic Scholar
Selective ERK Activation Differentiates Mouse and Human Tolerogenic Dendritic Cells, Expands Antigen-Specific Regulatory T Cells, and Suppresses Experimental Inflammatory Arthritis
F. Arce, K. Breckpot, Holly N. Stephenson, K. Karwacz +3 more
2011Arthritis & Rheumatism70 citations Open access
Semantic Scholar
Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials.
F. Rivellese, A. Nerviani, G. Giorli, Louise Warren +33 more
2023The Lancet Rheumatology62 citations Open access
Semantic Scholar
Abnormal CTLA‐4 function in T cells from patients with systemic lupus erythematosus
E. Jury, F. Flores-Borja, H. Kalsi, M. Lazarus +3 more
2010European Journal of Immunology62 citations Open access
Semantic Scholar
Efficacy and safety of obinutuzumab in systemic lupus erythematosus patients with secondary non-response to rituximab.
J. Arnold, S. Dass, S. Twigg, Colin H. Jones +7 more
2022Rheumatology52 citations Open access
Semantic Scholar
The yin and yang of regulatory T cells and inflammation in RA
C. A. Notley, M. Ehrenstein
2010Nature Reviews Rheumatology52 citations
Semantic Scholar
Belimumab after B cell depletion therapy in patients with systemic lupus erythematosus (BEAT Lupus) protocol: a prospective multicentre, double-blind, randomised, placebo-controlled, 52-week phase II clinical trial
Alexis Jones, P. Muller, C. Doré, Felicia Ikeji +5 more
2019BMJ Open47 citations Open access
Semantic Scholar
Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT
R. Gilbert, Xiao-Zhe Zhang, R. Sampson, M. Ehrenstein +8 more
2018Frontiers in Immunology45 citations Open access
Semantic Scholar
B cell resistance to Fas-mediated apoptosis contributes to their ineffective control by regulatory T cells in rheumatoid arthritis
L. Rapetti, K. Chavele, Catherine M. Evans, M. Ehrenstein
2013Annals of the Rheumatic Diseases41 citations Open access
Semantic Scholar
DNA methylation governs the dynamic regulation of inflammation by apoptotic cells during efferocytosis
C. A. Notley, Christine K. Jordan, Jenny L. McGovern, Mark A. Brown +1 more
2017Scientific Reports30 citations Open access
Semantic Scholar
Identification of biomarkers to stratify response to B-cell-targeted therapies in systemic lupus erythematosus: an exploratory analysis of a randomised controlled trial
M. Shipa, L. Santos, D. X. Nguyen, A. Embleton-Thirsk +6 more
2022The Lancet Rheumatology29 citations Open access
Semantic Scholar
Regulatory T-cell adoptive immunotherapy: potential for treatment of autoimmunity
G. Wright, M. Ehrenstein, H. Stauss
2011Expert Review of Clinical Immunology29 citations
Semantic Scholar
SCIENCE AND SOCIETY: The RA‐MAP Consortium: a working model for academia‐industry collaboration
A. Cope, M. Barnes, Alexandra Belson, M. Binks +31 more
201827 citations Open access
Semantic Scholar
Tuberculosis and anti-TNF treatment: experience of a central London hospital
S. Mankia, J. E. Peters, Swan Kang, S. Moore +1 more
2011Clinical Rheumatology27 citations
Semantic Scholar
Regulatory T cells as a biomarker for response to adalimumab in rheumatoid arthritis
D. X. Nguyen, A. Cotton, L. Attipoe, Coziana Ciurtin +2 more
2018Journal of Allergy and Clinical Immunology26 citations Open access
Semantic Scholar
Therapeutic potential of Tregs to treat rheumatoid arthritis.
G. Wright, H. Stauss, M. Ehrenstein
2011Seminars in Immunology25 citations Open access
Semantic Scholar
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients
J. Isaacs, S. Brockbank, A. Pedersen, Catharien M. U. Hilkens +148 more
2022Scientific Data22 citations Open access
Semantic Scholar
Tumor Necrosis Factor (TNF) Bioactivity at the Site of an Acute Cell-Mediated Immune Response Is Preserved in Rheumatoid Arthritis Patients Responding to Anti-TNF Therapy
R. Byng-Maddick, C. Turner, G. Pollara, M. Ellis +4 more
2017Frontiers in Immunology17 citations Open access
Semantic Scholar
CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22
A. Ezeonyeji, H. Baldwin, M. Vukmanovic-Stejic, M. Ehrenstein
2017Frontiers in Immunology16 citations Open access
Semantic Scholar
Methotrexate reduces withdrawal rates of TNF inhibitors due to ineffectiveness in rheumatoid arthritis but only in patients who are seropositive
M. Greenwood, M. Shipa, S. Yeoh, E. Roussou +2 more
2020Annals of the Rheumatic Diseases15 citations Open access
Semantic Scholar
Engulfment of Activated Apoptotic Cells Abolishes TGF-β–Mediated Immunoregulation via the Induction of IL-6
C. A. Notley, Mark A. Brown, Jenny L. McGovern, Christine K. Jordan +1 more
2015Journal of Immunology14 citations Open access
Semantic Scholar
Characterization of disease course and remission in early seropositive rheumatoid arthritis: results from the TACERA longitudinal cohort study
M. Barnes, S. Brockbank, I. Bruce, C. Ciurtin +17 more
2021Therapeutic Advances in Musculoskeletal Disease13 citations Open access
Semantic Scholar
Germinal center B cells govern their own fate via antibody feedback
Yang Zhang, M. Meyer-Hermann, Laura A. George, M. Figge +10 more
2013Journal of Experimental Medicine11 citations Open access
Semantic Scholar
Access to the next wave of biologic therapies (Abatacept and Tocilizumab) for the treatment of rheumatoid arthritis in England and Wales
Y. Chiu, A. Ostor, A. Hammond, K. Sokoll +6 more
2012Clinical Rheumatology11 citations Open access
Semantic Scholar
Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil
Mumina Akhtar, N. Nair, L. Carter, E. Vital +70 more
2023Arthritis Research & Therapy10 citations Open access
Semantic Scholar
Regulatory T cells enhance Th17 migration in psoriatic arthritis which is reversed by anti-TNF
D. X. Nguyen, H. Baldwin, A. Ezeonyeji, Mohammed Rohan Butt +1 more
2021iScience9 citations Open access
Semantic Scholar
A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site
G. Szylar, R. Wysoczanski, H. Marshall, D. Marks +3 more
2022Scientific Reports8 citations Open access
Semantic Scholar
Impact of a mid‐urethral synthetic mesh sling on long‐term risk of systemic conditions in women with stress urinary incontinence: a national cohort study
P. Muller, I. Gurol-Urganci, R. Thakar, M. Ehrenstein +2 more
2021BJOG: an International Journal of Obstetrics and Gynaecology8 citations Open access
Semantic Scholar
Approaches to optimising access to NICE-approved biologic anti-TNFs for patients with rheumatoid arthritis with moderately active disease
Peter C. Taylor, A. Askari, E. Choy, M. Ehrenstein +2 more
2023BMC Medicine7 citations Open access
Semantic Scholar
An unfavourable outcome following switching intravenous abatacept and tocilizumab to subcutaneous forms during the COVID-19 pandemic
Rishi Gupta, M. Shipa, S. Yeoh, P. Buck +1 more
2020Rheumatology7 citations Open access
Semantic Scholar
The synergistic efficacy of hydroxychloroquine with methotrexate is accompanied by increased erythrocyte mean corpuscular volume
Muhammad Ruhul Amin Shipa, S. Yeoh, A. Embleton-Thirsk, D. Mukerjee +1 more
2021Rheumatology6 citations Open access
Semantic Scholar
Safety and efficacy of belimumab after B cell depletion therapy in systemic LUPUS erythematosus (BEAT-LUPUS) trial: statistical analysis plan
P. Muller, K. Chowdhury, C. Gordon, M. Ehrenstein +1 more
2020Trials6 citations Open access
Semantic Scholar
Differences in management approaches for lupus nephritis within the UK
Sara T Ibrahim, Christopher J Edwards, M. Ehrenstein, B. Griffiths +8 more
2024Rheumatology Advances in Practice4 citations Open access
Semantic Scholar
Early reduction in circulating monocyte count predicts maintenance of remission in patients with rheumatoid arthritis treated with anti-TNF therapy
M. Shipa, R. Amarnani, S. Yeoh, M. Mainuddin +1 more
2021Annals of the Rheumatic Diseases4 citations Open access
Semantic Scholar

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