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J. Nettleship · SciRah

Researcher profile · Semantic Scholar

J. Nettleship

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J. Nettleship — researcher profile on SciRah

h-index: 28
Works: 129
Citations: 3,999

Most-cited papers

Affimer proteins are versatile and renewable affinity reagents
C. Tiede, R. Bedford, Sophie J. Heseltine, Gina A. Smith +42 more
2017eLife150 citations Open access
Semantic Scholar
Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering.
J. Nettleship, James Brown, M. Groves, A. Geerlof
2008Methods in molecular biology141 citations
Semantic Scholar
Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcεRI
M. Holdom, A. Davies, J. Nettleship, S. C. Bagby +8 more
2011Nature Structural &Molecular Biology136 citations Open access
Semantic Scholar
In situ macromolecular crystallography using microbeams
D. Axford, R. Owen, J. Aishima, J. Foadi +14 more
2012Acta Crystallographica Section D: Biological Crystallography118 citations Open access
Semantic Scholar
Sex‐based differences in severity and mortality in COVID‐19
M. Alwani, A. Yassin, Raed M. Al-Zoubi, O. Aboumarzouk +4 more
2021Reviews in Medical Virology116 citations Open access
Semantic Scholar
Recent advances in the production of proteins in insect and mammalian cells for structural biology.
J. Nettleship, R. Assenberg, J. Diprose, Nahid Rahman-Huq +1 more
2010Journal of Structural Biology107 citations
Semantic Scholar
Effects of testosterone replacement therapy withdrawal and re-treatment in hypogonadal elderly men upon obesity, voiding function and prostate safety parameters
A. Yassin, J. Nettleship, R. Talib, Y. Almehmadi +1 more
2016The Aging Male104 citations Open access
Semantic Scholar
Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling
Thomas A. Bowden, A. Aricescu, J. Nettleship, Christian Siebold +4 more
2009Structure97 citations Open access
Semantic Scholar
Testosterone suppresses the expression of regulatory enzymes of fatty acid synthesis and protects against hepatic steatosis in cholesterol-fed androgen deficient mice.
D. Kelly, J. Nettleship, S. Akhtar, V. Muraleedharan +5 more
2014Life Science93 citations
Semantic Scholar
Outrunning free radicals in room-temperature macromolecular crystallography
R. Owen, D. Axford, J. Nettleship, R. Owens +9 more
2012Acta Crystallographica Section D: Biological Crystallography79 citations Open access
Semantic Scholar
ENPP1 PROCESSES PROTEIN ADP-RIBOSYLATION IN VITRO
L. Palazzo, C. Daniels, J. Nettleship, Nahid Rahman +6 more
2016The FEBS Journal76 citations Open access
Semantic Scholar
Testosterone and coronary artery disease.
J. Nettleship, Richard D. Jones, K. Channer, T. Jones
2009Frontiers of Hormone Research55 citations
Semantic Scholar
A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cells.
J. Nettleship, Jing-Shan Ren, Nahid Rahman, N. Berrow +3 more
2008Protein Expression and Purification54 citations
Semantic Scholar
The production of glycoproteins by transient expression in Mammalian cells.
J. Nettleship, Nahid Rahman-Huq, R. Owens
2009Methods in molecular biology47 citations
Semantic Scholar
Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action
J. Robinson, E. W. Baxter, R. Owen, M. Thomsen +12 more
2017Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Transient expression in HEK 293 cells: an alternative to E. coli for the production of secreted and intracellular mammalian proteins.
J. Nettleship, P. Watson, Nahid Rahman-Huq, L. Fairall +8 more
2015Methods in molecular biology41 citations Open access
Semantic Scholar
The structure-function relationship of oncogenic LMTK3
A. Ditsiou, C. Cilibrasi, Nikiana Simigdala, A. Papakyriakou +25 more
2020Science Advances33 citations Open access
Semantic Scholar
Effects of continuous long‐term testosterone therapy (TTh) on anthropometric, endocrine and metabolic parameters for up to 10 years in 115 hypogonadal elderly men: real‐life experience from an observational registry study
A. Yassin, J. Nettleship, Y. Almehmadi, M. Salman +1 more
2016Andrologia31 citations Open access
Semantic Scholar
Long-term testosterone therapy improves liver parameters and steatosis in hypogonadal men: a prospective controlled registry study
A. Yassin, M. Alwani, R. Talib, Y. Almehmadi +5 more
2020The Aging Male29 citations Open access
Semantic Scholar
Testosterone replacement therapy improves the health-related quality of life of men diagnosed with late-onset hypogonadism
Y. Almehmadi, A. Yassin, J. Nettleship, F. Saad
2015Arab Journal of Urology27 citations Open access
Semantic Scholar
Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis
A. Awanye, Chun-Mien Chang, Jun X. Wheeler, H. Chan +8 more
2019Scientific Reports25 citations Open access
Semantic Scholar
Binding of (5S)-penicilloic acid to penicillin binding protein 3.
S. V. Van Berkel, J. Nettleship, I. Leung, J. Brem +7 more
2013ACS Chemical Biology25 citations Open access
Semantic Scholar
Early weight loss predicts the reduction of obesity in men with erectile dysfunction and hypogonadism undergoing long-term testosterone replacement therapy
M. Salman, D-J. Yassin, Huda Shoukfeh, J. Nettleship +1 more
2017The Aging Male24 citations Open access
Semantic Scholar
Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms
Jing-Shan Ren, J. Nettleship, A. Males, D. Stuart +1 more
2016FEBS Letters24 citations Open access
Semantic Scholar
The structure of a reduced form of OxyR from Neisseria meningitidis
S. Sainsbury, Jing-Shan Ren, J. Nettleship, N. J. Saunders +2 more
2010BMC Structural Biology24 citations Open access
Semantic Scholar
Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major
J. Timm, C. Bosch-Navarrete, E. Recio, J. Nettleship +3 more
2015PLoS Neglected Tropical Diseases22 citations Open access
Semantic Scholar
Structures of an alanine racemase from Bacillus anthracis (BA0252) in the presence and absence of (R)-1-aminoethylphosphonic acid (L-Ala-P).
K. Au, Jing-Shan Ren, T. Walter, K. Harlos +4 more
2008Acta Crystallographica. Section F : Structural Biology and Crystallization Communications20 citations Open access
Semantic Scholar
Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase–dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance
M. Yogavel, J. Nettleship, Amit Kumar Sharma, K. Harlos +6 more
2018Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1
Victoria Arena de Souza, David J Scott, J. Nettleship, Nahid Rahman +3 more
2015PLoS ONE18 citations Open access
Semantic Scholar
Testosterone and Covid‐19: An update
A. Yassin, Ridwan Sabsigh, Raed M. Al-Zoubi, O. Aboumarzouk +3 more
2022Reviews in Medical Virology17 citations Open access
Semantic Scholar
GFP-based expression screening of membrane proteins in insect cells using the baculovirus system.
Nien-Jen Hu, Heather Rada, Nahid Rahman, J. Nettleship +5 more
2015Methods in molecular biology16 citations
Semantic Scholar
Is there a relationship between the severity of erectile dysfunction and the comorbidity profile in men with late onset hypogonadism?
A. Yassin, J. Nettleship, Y. Almehmadi, D-J. Yassin +2 more
2015Arab Journal of Urology16 citations Open access
Semantic Scholar
Substituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases.
Martin Roatsch, D. Robaa, Martin Pippel, J. Nettleship +9 more
2016Future Medicinal Chemistry15 citations Open access
Semantic Scholar
S-Adenosyl-S-carboxymethyl-l-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA
R. T. Byrne, F. Whelan, P. Aller, L. Bird +7 more
2013Acta Crystallographica Section D: Biological Crystallography15 citations Open access
Semantic Scholar
Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
L. Bird, Jing-Shan Ren, J. Nettleship, G. Folkers +2 more
2010BMC Structural Biology15 citations Open access
Semantic Scholar
The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus
Jing-Shan Ren, J. Nettleship, G. Harris, W. Mwangi +8 more
2019Molecular Immunology14 citations Open access
Semantic Scholar
Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region
Young Chan Kim, C. López-Camacho, J. Nettleship, Nahid Rahman +11 more
2018Virology Journal14 citations Open access
Semantic Scholar
Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment
J. Nettleship, Jing-Shan Ren, David J. F. Scott, Nahid Rahman +5 more
2013BMC Structural Biology14 citations Open access
Semantic Scholar
Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
L. Romanello, V. Serrão, J. R. Torini, L. Bird +7 more
2017Molecular and biochemical parasitology (Print)13 citations
Semantic Scholar
Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei
M. Valente, J. Timm, Víctor M. Castillo-Acosta, L. Ruiz-Pérez +6 more
2016Molecular Microbiology13 citations Open access
Semantic Scholar
Functional and structural proteomics of glycoproteins
R. Owens, J. Nettleship
201113 citations
Semantic Scholar
A streamlined implementation of the glutamine synthetase-based protein expression system
Rachel G. Knox, J. Nettleship, V. Chang, ,-Zhao Hui +5 more
2013BMC Biotechnology11 citations Open access
Semantic Scholar
Structural Biology of Glycoproteins
J. Nettleship
201211 citations Open access
Semantic Scholar
Overview of a High-Throughput Pipeline for Streamlining the Production of Recombinant Proteins.
J. Nettleship, Heather Rada, R. Owens
2019Methods in molecular biology10 citations
Semantic Scholar
Converting monoclonal antibodies into Fab fragments for transient expression in mammalian cells.
J. Nettleship, A. Flanagan, Nahid Rahman-Huq, R. Hamer +1 more
2012Methods in molecular biology10 citations Open access
Semantic Scholar
Effectiveness and tolerability of parenteral testosterone undecanoate: a post-marketing surveillance study
Jan Wolf, Dieter Keipert, Heiko Motazedi, M. Ernst +2 more
2017The Aging Male8 citations Open access
Semantic Scholar
Expression Screening of Integral Membrane Proteins by Fusion to Fluorescent Reporters.
L. Bird, J. Nettleship, Valtteri J. Järvinen, Heather Rada +2 more
2016Advances in Experimental Medicine and Biology8 citations
Semantic Scholar
Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118.
C. Lobley, P. Aller, A. Douangamath, Yamini Reddivari +7 more
2012Acta Crystallographica. Section F : Structural Biology and Crystallization Communications8 citations Open access
Semantic Scholar
Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size
A. Yassin, M. Alwani, Raed M. Al-Zoubi, O. Aboumarzouk +4 more
2023International Urology and Nephrology7 citations Open access
Semantic Scholar
Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2
Z. Soloviev, Joshua M. A Bullock, Juliette M. B. James, Andrea C. Sauerwein +5 more
2022Biochimica et Biophysica Acta - Proteins and Proteomics7 citations Open access
Semantic Scholar

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