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S. Krilis · SciRah

Researcher profile · Semantic Scholar

S. Krilis

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S. Krilis — researcher profile on SciRah

h-index: 36
Works: 138
Citations: 5,073

Most-cited papers

The pathogenesis of the antiphospholipid syndrome.
B. Giannakopoulos, S. Krilis
2013New England Journal of Medicine684 citations
Semantic Scholar
Current concepts on the pathogenesis of the antiphospholipid syndrome.
B. Giannakopoulos, F. Passam, S. Rahgozar, S. Krilis
2007Blood253 citations Open access
Semantic Scholar
How we diagnose the antiphospholipid syndrome.
B. Giannakopoulos, F. Passam, Y. Ioannou, S. Krilis
2009Blood199 citations Open access
Semantic Scholar
Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka.
D. Andresen, A. Donaldson, Lennart Choo, Adrian Knox +5 more
2005The Lancet177 citations
Semantic Scholar
Use of Single Point Mutations in Domain I of β2-Glycoprotein I to Determine Fine Antigenic Specificity of Antiphospholipid Autoantibodies1
G. Iverson, S. Reddel, E. J. Victoria, K. Cockerill +6 more
2002Journal of Immunology156 citations Open access
Semantic Scholar
Development of Mast Cells and Importance of Their Tryptase and Chymase Serine Proteases in Inflammation and Wound Healing
Jeffrey Douaiher, J. Succar, L. Lancerotto, M. Gurish +4 more
2014Advances in Immunology150 citations Open access
Semantic Scholar
Beta-2 glycoprotein1: function in health and disease
S. Miyakis, B. Giannakopoulos, S. Krilis
2014138 citations
Semantic Scholar
Essential role for mast cell tryptase in acute experimental colitis
M. Hamilton, M. Sinnamon, Gregory D. Lyng, J. Glickman +7 more
2010Proceedings of the National Academy of Sciences of the United States of America132 citations Open access
Semantic Scholar
Naturally occurring free thiols within beta 2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury.
Y. Ioannou, Jing-Yun Zhang, F. Passam, S. Rahgozar +7 more
2010Blood132 citations
Semantic Scholar
Novel Assays of Thrombogenic Pathogenicity in the Antiphospholipid Syndrome Based on the Detection of Molecular Oxidative Modification of the Major Autoantigen β2-Glycoprotein I
Y. Ioannou, Jing-Yun Zhang, M. Qi, Lu Gao +13 more
2011Arthritis & Rheumatism115 citations Open access
Semantic Scholar
RasGRP4, a New Mast Cell-restricted Ras Guanine Nucleotide-releasing Protein with Calcium- and Diacylglycerol-binding Motifs
Yi Yang, Li-Xin Li, G. W. Wong, S. Krilis +3 more
2002Journal of Biological Chemistry110 citations Open access
Semantic Scholar
CXCR 4 HIV-1 susceptible due to their surface expression of CD 4 and the chemokine Mast cells / basophils in the peripheral blood of allergic individuals who
R. Wadley, S. Reddel, Jian C. Qi, C. Archis +10 more
2001104 citations
Semantic Scholar
Anti-β2-Glycoprotein I Autoantibodies from Patients with the “Antiphospholipid” Syndrome Bind to β2-Glycoprotein I with Low Affinity: Dimerization of β2-Glycoprotein I Induces a Significant Increase in Anti-β2-Glycoprotein I Antibody Affinity
Y. Sheng, D. Kandiah, S. Krilis
1998Journal of Immunology98 citations
Semantic Scholar
Beta 2-Glycoprotein I binds factor XI and inhibits its activation by thrombin and factor XIIa: loss of inhibition by clipped beta 2-glycoprotein I.
T. Shi, G. Iverson, Jian C Qi, K. Cockerill +3 more
2004Proceedings of the National Academy of Sciences of the United States of America95 citations Open access
Semantic Scholar
Identification of basophilic cells that express mast cell granule proteases in the peripheral blood of asthma, allergy, and drug-reactive patients.
Li-Xin Li, Yong Li, S. Reddel, Maya Cherrian +3 more
1998Journal of Immunology92 citations
Semantic Scholar
Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis*
P. Hansbro, Matthew J. Hamilton, M. Fricker, Shaan L. Gellatly +9 more
2014Journal of Biological Chemistry85 citations Open access
Semantic Scholar
How I treat the antiphospholipid syndrome.
B. Giannakopoulos, S. Krilis
2009Blood85 citations Open access
Semantic Scholar
Impaired Thrombin Generation in β2-Glycoprotein I Null Mice*
Y. Sheng, S. Reddel, H. Herzog, Ying-Xia Wang +4 more
2001Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Human and mouse mast cells use the tetraspanin CD9 as an alternate interleukin-16 receptor.
Jian C. Qi, Jing Wang, Sravan Mandadi, Kumiko E. Tanaka +7 more
2006Blood82 citations Open access
Semantic Scholar
Distinguishing Features of Anti-β2 Glycoprotein I Antibodies between Patients with Leprosy and the Antiphospholipid Syndrome
J. Arvieux, Yves Renaudineau, I. Mané, R. Perraut +2 more
2002Thrombosis and Haemostasis81 citations
Semantic Scholar
Labile Zinc and Zinc Transporter ZnT4 in Mast Cell Granules: Role in Regulation of Caspase Activation and NF-κB Translocation1
L. Ho, R. Ruffin, C. Murgia, Li-Xin Li +2 more
2004Journal of Immunology78 citations Open access
Semantic Scholar
Biochemical and Functional Characterization of Human Transmembrane Tryptase (TMT)/Tryptase γ
G. W. Wong, P. Foster, S. Yasuda, Jian C. Qi +7 more
2002Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Association of mast cells with fibrosis and fatty infiltration in the minor salivary glands of patients with Sjögren's syndrome.
F. Skopouli, L. Li, D. Boumba, S. Stefanaki +3 more
1998Clinical and Experimental Rheumatology66 citations
Semantic Scholar
Effect of beta2-glycoprotein I null mutation on reproductive outcome and antiphospholipid antibody-mediated pregnancy pathology in mice.
S. Robertson, C. Roberts, Eline van Beijering, K. Pensa +3 more
2004Molecular human reproduction60 citations
Semantic Scholar
Factor XI is a substrate for oxidoreductases: enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.
B. Giannakopoulos, Lu Gao, M. Qi, Jason W. H. Wong +8 more
2012Journal of Autoimmunity53 citations
Semantic Scholar
Human Tryptase ε (PRSS22), a New Member of the Chromosome 16p13.3 Family of Human Serine Proteases Expressed in Airway Epithelial Cells*
G. W. Wong, S. Yasuda, M. Madhusudhan, Li-Xin Li +4 more
2001Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Ro 60 functions as a receptor for beta(2)-glycoprotein I on apoptotic cells.
Joanne H. Reed, B. Giannakopoulos, Michael W. Jackson, S. Krilis +1 more
2009Arthritis & Rheumatism46 citations
Semantic Scholar
Dapsone hypersensitivity syndrome causing disseminated intravascular coagulation
M. Figtree, S. Miyakis, Kumiko Tanaka, L. Martin +2 more
2009BMJ Case Reports44 citations Open access
Semantic Scholar
IL-16 Regulation of Human Mast Cells/Basophils and Their Susceptibility to HIV-11
Jian C. Qi, R. Stevens, R. Wadley, A. Collins +8 more
2002Journal of Immunology38 citations Open access
Semantic Scholar
Laboratory tests for the antiphospholipid syndrome: current concepts.
F. Passam, S. Krilis
2004Pathology (Sydney)37 citations
Semantic Scholar
Antibodies to β2-Glycoprotein-I: Urea Resistance, Binding Specificity, and Association with Thrombosis
P. Vlachoyiannopoulos, C. Petrovas, M. Tektonidou, S. Krilis +1 more
1998Journal of Clinical Immunology36 citations
Semantic Scholar
Beta2-glycoprotein I binds thrombin via exosite I and exosite II: anti-beta2-glycoprotein I antibodies potentiate the inhibitory effect of beta2-glycoprotein I on thrombin-mediated factor XIa generation.
S. Rahgozar, Qiu-Xia Yang, B. Giannakopoulos, Xiao-yu Yan +2 more
2007Arthritis & Rheumatism35 citations
Semantic Scholar
Anti-beta 2-glycoprotein I autoantibodies from patients with the "antiphospholipid" syndrome bind to beta 2-glycoprotein I with low affinity: dimerization of beta 2-glycoprotein I induces a significant increase in anti-beta 2-glycoprotein I antibody affinity.
Y. Sheng, D. Kandiah, S. Krilis
1998Journal of Immunology35 citations
Semantic Scholar
Beta-2 glycoprotein I and its role in antiphospholipid syndrome-lessons from knockout mice.
S. Miyakis, S. Robertson, S. Krilis
2004Clinical Immunology33 citations
Semantic Scholar
Tryptase 4, a New Member of the Chromosome 17 Family of Mouse Serine Proteases*
G. Wong, Li-Xin Li, M. Madhusudhan, S. Krilis +4 more
2001Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22.
S. Yasuda, N. Morokawa, G. W. Wong, A. Rossi +7 more
2005Blood32 citations Open access
Semantic Scholar
Testing for and Clinical Significance of Anticardiolipin Antibodies
S. Reddel, S. Krilis
1999Clinical Diagnostic Laboratory Immunology32 citations Open access
Semantic Scholar
Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells.
G. W. Wong, S. Yasuda, M. Madhusudhan, L. Li +4 more
2001Journal of Biological Chemistry29 citations
Semantic Scholar
Laboratory methods to detect antiphospholipid antibodies.
S. Krilis, B. Giannakopoulos
2014Hematology. American Society of Hematology. Education Program26 citations Open access
Semantic Scholar
New Insights into the Biology and Pathobiology of Beta2-Glycoprotein I
B. Giannakopoulos, Peyman Mirarabshahi, S. Krilis
2011Current Rheumatology Reports26 citations
Semantic Scholar
Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: potentiation of this effect in the presence of anti-beta2-glycoprotein I autoantibodies.
S. Rahgozar, B. Giannakopoulos, Xiao-yu Yan, Jiewei Wei +3 more
2008Arthritis & Rheumatism26 citations
Semantic Scholar
Ras Guanine Nucleotide-releasing Protein-4 (RasGRP4) Involvement in Experimental Arthritis and Colitis*
Roberto Adachi, S. Krilis, P. Nigrovic, M. Hamilton +5 more
2012Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Anti-β2-glycoprotein I antibodies and the antiphospholipid syndrome
Zhe Li, S. Krilis
200325 citations
Semantic Scholar
Gram Negative Bacterial Inflammation Ameliorated by the Plasma Protein Beta 2-Glycoprotein I
Saijun Zhou, Gang Chen, M. Qi, F. El‐Assaad +8 more
2016Scientific Reports24 citations Open access
Semantic Scholar
Posttranslational forms of beta 2-glycoprotein I in the pathogenesis of the antiphospholipid syndrome
F. El‐Assaad, S. Krilis, B. Giannakopoulos
2016Thrombosis Journal21 citations Open access
Semantic Scholar
The Diacylglycerol-dependent Translocation of Ras Guanine Nucleotide-releasing Protein 4 inside a Human Mast Cell Line Results in Substantial Phenotypic Changes, Including Expression of Interleukin 13 Receptor α2*
G. Katsoulotos, M. Qi, Jian C. Qi, Kumiko E. Tanaka +5 more
2008Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome.
J. Weaver, S. Krilis, B. Giannakopoulos
2018Free Radical Biology & Medicine17 citations
Semantic Scholar
Βeta-2-glycoprotein I exerts antithrombotic function through its domain V in mice.
F. Passam, Gang Chen, V. Chen, M. Qi +2 more
2021Journal of Autoimmunity15 citations
Semantic Scholar
Do Beta 2-Glycoprotein I Disulfide Bonds Protect the Human Retina in the Setting of Age-Related Macular Degeneration?
M. Qi, Mahmoud Abdelatti, M. Krilis, M. Madigan +7 more
2015Antioxidants and Redox Signaling15 citations
Semantic Scholar
Heterogeneity of Lupus Anticoagulant (LA) Antibodies: LA Activity in Dilute Russell’s Viper Venom Time and Dilute Kaolin Clotting Time Detect Different Populations of Antibodies in Patients with the “Antiphospholipid” Syndrome
D. Kandiah, S. Krilis
1998Thrombosis and Haemostasis15 citations
Semantic Scholar

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R. Stevens×14
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Jian C. Qi×8
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Jian C. Qi — researcher profile on SciRah
G. W. Wong×7
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Li-Xin Li — researcher profile on SciRah

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S. Miyakis — researcher profile on SciRah