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Y. Cho · SciRah

Researcher profile · Semantic Scholar

Y. Cho

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Y. Cho — researcher profile on SciRah

h-index: 24
Works: 51
Citations: 2,044

Most-cited papers

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5
Konstantinos J. Mavrakis, E. Mcdonald, M. Schlabach, E. Billy +40 more
2016Science534 citations
Semantic Scholar
Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: a synthetic route to anticancer vaccine candidates.
G. Ragupathi, F. Koide, P. Livingston, Y. Cho +8 more
2006Journal of the American Chemical Society144 citations
Semantic Scholar
Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity.
J. T. Hunt, Charles Z. Ding, R. Batorsky, M. Bednarz +19 more
2000Journal of Medicinal Chemistry120 citations Open access
Semantic Scholar
Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor.
Y. Cho, Julian R. Levell, Gang Liu, T. Caferro +23 more
2017ACS Medicinal Chemistry Letters110 citations Open access
Semantic Scholar
Discovery of (E)-9,10-dehydroepothilones through chemical synthesis: on the emergence of 26-trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B as a promising anticancer drug candidate.
A. Rivkin, Fumihiko Yoshimura, Ana E. Gabarda, Y. Cho +3 more
2004Journal of the American Chemical Society87 citations
Semantic Scholar
4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
Y. Cho, Maria Borland, C. Brain, C. Chen +17 more
2010Journal of Medicinal Chemistry86 citations Open access
Semantic Scholar
Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity.
Xiaoling Xie, D. Baird, Kimberly Bowen, V. Cápka +19 more
2017Structure61 citations Open access
Semantic Scholar
Total synthesis of (+/-)-jiadifenin and studies directed to understanding its SAR: probing mechanistic and stereochemical issues in palladium-mediated allylation of enolate-like structures.
David A. Carcache, Y. Cho, Zihao Hua, Yuan Tian +2 more
2006Journal of the American Chemical Society61 citations
Semantic Scholar
Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
M. Shultz, Xue-Ying Cao, C. Chen, Y. Cho +33 more
2011Journal of Medicinal Chemistry59 citations Open access
Semantic Scholar
Design and total synthesis of a superior family of epothilone analogues, which eliminate xenograft tumors to a nonrelapsable state.
Ting-Chao Chou, Hua-Jin Dong, A. Rivkin, Fumihiko Yoshimura +4 more
2003Angewandte Chemie59 citations
Semantic Scholar
Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D.
Amos B. Smith, N. Kanoh, Haruaki Ishiyama, N. Minakawa +5 more
2003Journal of the American Chemical Society58 citations
Semantic Scholar
Application of ring-closing metathesis reactions in the synthesis of epothilones.
A. Rivkin, Y. Cho, Ana E. Gabarda, Fumihiko Yoshimura +1 more
2004Journal of Natural Products49 citations
Semantic Scholar
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1.
Julian R. Levell, T. Caferro, Gregg Chenail, I. Dix +24 more
2017ACS Medicinal Chemistry Letters45 citations Open access
Semantic Scholar
Total synthesis of (+/-)-jiadifenin, a non-peptidyl neurotrophic modulator.
Y. Cho, David A. Carcache, Yuan Tian, Yue-Ming Li +1 more
2004Journal of the American Chemical Society45 citations
Semantic Scholar
CONVENIENT WACKER OXIDATIONS WITH SUBSTOICHIOMETRIC CUPRIC ACETATE
Amos B. Smith, Y. Cho, G. Friestad
199845 citations Open access
Semantic Scholar
Usefulness of Eschar PCR for Diagnosis of Scrub Typhus
Seung-Hyun Lee, Dong-Min Kim, Y. Cho, S. Yoon +1 more
2006Journal of Clinical Microbiology43 citations Open access
Semantic Scholar
Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors.
Y. Cho, H. Angove, C. Brain, C. Chen +32 more
2012ACS Medicinal Chemistry Letters41 citations Open access
Semantic Scholar
Discovery and structure-activity relationships of imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase
Charles Z. Ding, R. Batorsky, R. Bhide, Hannguang J. Chao +19 more
1999Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo.
Kai-Da Wu, Y. Cho, J. Katz, V. Ponomarev +3 more
2005Proceedings of the National Academy of Sciences of the United States of America36 citations Open access
Semantic Scholar
Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824).
Y. Cho, L. Whitehead, Jian-Ke Li, C. Chen +16 more
2010Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Radical cyclization of β-alkoxyacrylates: Stereoselective synthesis of (−)-trans-Kumausyne
E. Lee, S. Yoo, Y. Cho, Hwan‐Sung Cheon +1 more
199730 citations
Semantic Scholar
Indole diterpene synthetic studies: development of a second-generation synthetic strategy for (+)-nodulisporic acids A and B.
Amos B. Smith, L. Kūrti, A. H. Davulcu, Y. Cho +1 more
2007Journal of Organic Chemistry29 citations
Semantic Scholar
Development of a Scalable Synthesis of a Common Eastern Tricyclic Lactone for Construction of the Nodulisporic Acids
Amos B. Smith, L. Kūrti, Akin H. Davulcu, Y. Cho
200729 citations
Semantic Scholar
Indole diterpene synthetic studies. Total synthesis of (+)-nodulisporic acid F and construction of the heptacyclic cores of (+)-nodulisporic acids A and B and (-)-nodulisporic acid D.
Amos B. Smith, A. H. Davulcu, Y. Cho, K. Ohmoto +2 more
2007Journal of Organic Chemistry27 citations Open access
Semantic Scholar
The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.
M. Shultz, Jianmei Fan, C. Chen, Y. Cho +19 more
2011Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Second generation epothilones: Discovery of fludelone and its extraordinary antitumor properties
Y. Cho, Kai-Da Wu, M. Moore, Ting-Chao Chou +1 more
2005Drugs of the future22 citations
Semantic Scholar
Nodulisporic acid A synthetic studies. 2. Construction of an eastern hemisphere subtarget.
Amos B. Smith, Y. Cho, Haruaki Ishiyama
2001Organic Letters22 citations
Semantic Scholar
Organic synthesis in pursuit of immunology: large-scale synthesis of peracetylated GM2 glycosylamino acid for preparation of a multiantigenic prostate cancer vaccine.
Y. Cho, Qian Wan, S. Danishefsky
2005Bioorganic & Medicinal Chemistry19 citations
Semantic Scholar
Design, synthesis, and evaluation of azepine-based cryptophycin mimetics
Amos B. Smith, Y. Cho, George R. Pettit, R. Hirschmann
200317 citations
Semantic Scholar
Nodulisporic acid A synthetic studies. 1. Overall strategy and construction of a western hemisphere subtarget.
Amos B. Smith, Haruaki Ishiyama, Y. Cho, K. Ohmoto
2001Organic Letters17 citations
Semantic Scholar
Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors.
U. Argikar, M. Blatter, D. Bednarczyk, Zhuoliang Chen +16 more
2022Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors.
Qian Zhao, J. R. Manning, J. Sutton, Abran Costales +21 more
2018ACS Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Spontaneous Pt Deposition on Defective Surfaces of In2O3 Nanocrystals Confined within Cavities of Hollow Silica Nanoshells: Pt Catalyst-Modified ITO Electrode with Enhanced ECL Performance.
Y. Cho, S. Kim, Youngwon Ju, Junghoon Kim +4 more
2017ACS Applied Materials and Interfaces10 citations
Semantic Scholar
Abstract LB-017: Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to marked dependence on PRMT5
Konstantinos J. Mavrakis, E. Mcdonald, M. Schlabach, E. Billy +32 more
20166 citations
Semantic Scholar
PQQ-dependent organic acid production and effect on common bean growth by Rhizobium tropici CIAT 899
Y. Cho, R. Park, Yong-Woong Kim, Hoon Hwangbo +5 more
20035 citations
Semantic Scholar
Abstract IA022: DYP688, a first-in-class PMEL17-targeted antibody drug conjugate delivering a Gq/11-specific inhibitor for the treatment of metastatic uveal melanoma
Josephzore Wk, Joseph A. D'Alessio, P. Yerramilli-Rao, J. Blankenship +23 more
2024Molecular Cancer Therapeutics3 citations
Semantic Scholar
Chemo- and regioselective halogenation of 4-(pyrazol-4-yl)-pyrimidines
Y. Cho, Ying Hou, C. Chen, M. Sung
20092 citations
Semantic Scholar
Indole Diterpene Synthetic Studies: Development of a Second‐Generation Synthetic Strategy for (+)‐Nodulisporic Acids A and B.
A. B. Iii Smith, Laszlo Kuerti, A. H. Davulcu, Y. Cho +1 more
20072 citations
Semantic Scholar
Application of Ring‐Closing Metathesis Reactions in the Synthesis of Epothilones
A. Rivkin, Y. Cho, Ana E. Gabarda, Fumihiko Yoshimura +1 more
20042 citations
Semantic Scholar
Total Synthesis of (.+-.)-Jiadifenin and Studies Directed to Understanding Its SAR: Probing Mechanistic and Stereochemical Issues in Palladium-Mediated Allylation of Enolate-Like Structures.
David A. Carcache, Y. Cho, Zihao Hua, Yuan Tian +2 more
20061 citations
Semantic Scholar
Radical Cyclization of β‐Alkoxyacrylates: Stereoselective Synthesis of (‐)‐trans‐Kumausyne.
E. Lee, S. Yoo, Y. Cho, Hwan‐Sung Cheon +1 more
19981 citations
Semantic Scholar
phospho-Akt after DNA damage and to a weaker accumulation of the pro-apoptotic protein PUMA as compared with those in MDMX-expressing
Konstantinos J. Mavrakis, E. Mcdonald, M. Schlabach, E. Billy +40 more
20160 citations
Semantic Scholar
Liganded X-ray crystal structure of cyclin dependent kinase 6 (CDK6)
Y. Cho, H. Angove, C. Brain, C. Chen +31 more
20130 citations
Semantic Scholar
B deacetylase inhibitors based hydroxamate
M. Shultz, C. Chen, Y. Cho, Lei Jiang +4 more
20090 citations
Semantic Scholar
Total Synthesis of (.+-.)-Jiadifenin, a Non-peptidyl Neurotrophic Modulator.
Y. Cho, David A. Carcache, Yuan Tian, Yue-Ming Li +1 more
20050 citations
Semantic Scholar
Synthesis of epothilones, intermediates thereof, analogs and their use
S. Danishefsky, A. Rivkin, Fumihiko Yoshimura, Ortega Ana Esther Gabarda +3 more
20030 citations
Semantic Scholar
Part I. First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues. Part II. Studies toward the total synthesis of (+)-nodulisporic acid A
Y. Cho
20020 citations
Semantic Scholar
Nodulisporic Acid A Synthetic Studies. Part 2. Construction of an Eastern Hemisphere Subtarget (I).
Amos B. Smith, Y. Cho, Haruaki Ishiyama
20020 citations
Semantic Scholar
Nodulisporic Acid A (I) Synthetic Studies. Part 1. Overall Strategy and Construction of a Western Hemisphere Subtarget (II).
Amos B. Smith, Haruaki Ishiyama, Y. Cho, K. Ohmoto
20020 citations
Semantic Scholar
Isolation and Identification of Phosphate Solubilizing Bacteria from Rhizosphere Soil and Organic Acid Production
Y. Cho, Kil-Yong Kim, B. Shon, R. Park +1 more
20000 citations
Semantic Scholar

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