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J. Kieswich · SciRah

Researcher profile · Semantic Scholar

J. Kieswich

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J. Kieswich — researcher profile on SciRah

h-index: 22
Works: 44
Citations: 2,178

Most-cited papers

Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.
E. Sharples, N. Patel, P. Brown, K. Stewart +8 more
2004Journal of the American Society of Nephrology425 citations Open access
Semantic Scholar
Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5.
P. Caton, N. Nayuni, J. Kieswich, N. Khan +2 more
2010Journal of Endocrinology211 citations
Semantic Scholar
Estrogen protects the blood-brain barrier from inflammation-induced disruption and increased lymphocyte trafficking.
E. Maggioli, S. McArthur, C. Mauro, J. Kieswich +4 more
2016Brain, behavior, and immunity166 citations Open access
Semantic Scholar
Generation of endogenous hydrogen sulfide by cystathionine γ-lyase limits renal ischemia/reperfusion injury and dysfunction
Pinpat Tripatara, N. Patel, M. Collino, M. Gallicchio +8 more
2008Laboratory Investigation166 citations Open access
Semantic Scholar
Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function
P. Caton, J. Kieswich, M. Yaqoob, M. Holness +1 more
2011Diabetologia131 citations Open access
Semantic Scholar
Dexamethasone ameliorates renal ischemia-reperfusion injury.
Sanjeev Kumar, D. A. Allen, J. Kieswich, N. Patel +6 more
2009Journal of the American Society of Nephrology130 citations Open access
Semantic Scholar
Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients
P. Caton, S. Richardson, J. Kieswich, M. Bugliani +6 more
2013Diabetologia107 citations Open access
Semantic Scholar
Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically‐obese db/db mice
P. Caton, J. Kieswich, M. Yaqoob, M. Holness +1 more
2011Diabetes, obesity and metabolism100 citations
Semantic Scholar
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide
P. Andrikopoulos, J. Aron-Wisnewsky, R. Chakaroun, A. Myridakis +99 more
2023Nature Communications79 citations Open access
Semantic Scholar
Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor.
S. Coldewey, Areeg I. Khan, A. Kapoor, M. Collino +9 more
2013Kidney International77 citations Open access
Semantic Scholar
The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling.
P. Andrikopoulos, J. Kieswich, Sabrina Pacheco, L. Nadarajah +4 more
2018Journal of the American Society of Nephrology66 citations Open access
Semantic Scholar
Ischemic Conditioning Protects the Uremic Heart in a Rodent Model of Myocardial Infarction
Conor J. Byrne, K. McCafferty, J. Kieswich, S. Harwood +4 more
2012Circulation60 citations Open access
Semantic Scholar
IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.
Jian-Min Chen, J. Kieswich, F. Chiazza, A. Moyes +9 more
2017Journal of the American Society of Nephrology56 citations Open access
Semantic Scholar
Monomeric eNAMPT in the development of experimental diabetes in mice: a potential target for type 2 diabetes treatment
J. Kieswich, Sophie R. Sayers, M. Silvestre, S. Harwood +2 more
2016Diabetologia52 citations Open access
Semantic Scholar
Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues
Madeeha H. Sheikh, M. Errede, A. d'Amati, N. Khan +18 more
2021The FASEB Journal44 citations Open access
Semantic Scholar
A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5
S. Tudhope, Chung‐Chi Wang, John L. Petrie, L. Potts +6 more
2011Diabetes43 citations Open access
Semantic Scholar
Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation
Marta Bagnati, B. Ogunkolade, Catriona J. Marshall, C. Tucci +11 more
2016Cell Death and Disease41 citations Open access
Semantic Scholar
Endothelial Angiogenesis and Barrier Function in Response to Thrombin Require Ca2+ Influx through the Na+/Ca2+ Exchanger*
P. Andrikopoulos, J. Kieswich, S. Harwood, A. Baba +5 more
2015Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia
A. Chapagain, P. Caton, J. Kieswich, P. Andrikopoulos +10 more
2014Proceedings of the National Academy of Sciences of the United States of America36 citations Open access
Semantic Scholar
Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter
John L. Petrie, Z. Al-Oanzi, C. Arden, S. Tudhope +5 more
2012Molecular and Cellular Biology35 citations Open access
Semantic Scholar
Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale
David W. Randall, J. Kieswich, J. Swann, K. McCafferty +4 more
2019Microbiome27 citations Open access
Semantic Scholar
A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain
J. Kieswich, Jianmin Chen, Samira Alliouachene, P. Caton +3 more
2018BMC Nephrology25 citations Open access
Semantic Scholar
Albumin stimulates cell growth, l-arginine transport, and metabolism to polyamines in human proximal tubular cells.
N. Ashman, S. Harwood, J. Kieswich, D. A. Allen +3 more
2005Kidney International17 citations Open access
Semantic Scholar
A Possible Explanation for Anemia in Patients Treated With Mycophenolic Acid
Taryn Pile, J. Kieswich, S. Harwood, M. Yaqoob
2011Transplantation14 citations Open access
Semantic Scholar
Gut Dysbiosis in Experimental Kidney Disease: A Meta-Analysis of Rodent Repository Data
David W. Randall, J. Kieswich, L. Hoyles, K. McCafferty +2 more
2023Journal of the American Society of Nephrology11 citations Open access
Semantic Scholar
Oral dysbiosis initiates periodontal disease in experimental kidney disease
David W. Randall, A. Alsam, J. Kieswich, Susan Joseph +8 more
2024Nephrology, Dialysis and Transplantation7 citations Open access
Semantic Scholar
A Key Role for Interferon Regulatory Factors in Mediating Early-Life Metabolic Defects in Male Offspring of Maternal Protein Restricted Rats
M. Silvestre, J. Kieswich, Mohammad Yaqoob, M. Holness +2 more
2014Hormone and Metabolic Research4 citations Open access
Semantic Scholar
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide with implications for heart and kidney disorders.
P. Andrikopoulos, J. Aron-Wisnewsky, R. Chakaroun, A. Myridakis +38 more
2022medRxiv3 citations Open access
Semantic Scholar
Immunohistochemistry of Kidney a-SMA, Collagen 1, and Collagen 3, in A Novel Mouse Model of Reno-cardiac Syndrome.
J. Kieswich, Jian-Min Chen, Samira Alliouachene, P. Caton +3 more
2020Bio-protocol3 citations Open access
Semantic Scholar
Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia
G. Dreyer, J. Kieswich, S. Harwood, A. Ahluwalia +1 more
2019Bioscience Reports2 citations Open access
Semantic Scholar
Divergent roles of skeletal muscle 11β-HSD1 in age-related and chronic kidney disease-associated sarcopenia.
M. Sagmeister, A. Crastin, Bradley W. Welsh, Louise Firkins +15 more
2026European Journal of Endocrinology1 citations Open access
Semantic Scholar
Artesunate alleviates kidney fibrosis by restoring klotho protein and suppressing Wnt/β-catenin signalling pathway
Goran H. Mohammad, J. Kieswich, Abhishek Kumar, Kieran McCafferty +3 more
2025Frontiers in Cell and Developmental Biology1 citations
Semantic Scholar
Uremia causes dysbiosis-mediated periodontal disease
D. Randall, A. Alsam, J. Kieswich, S. Joseph +9 more
20211 citations Open access
Semantic Scholar
Role of reverse-mode NCX in thrombin EC signalling
P. Andrikopoulos, J. Kieswich, S. Harwood, A. Baba +6 more
20151 citations
Semantic Scholar
Artesunate Alleviate Kidney Fibrosis by Restoring Klotho Protein and Suppressing Wnt/β-Catenin Signalling Pathway
G. Mohammad, J. Kieswich, Abhishek Kumar, Kieran McCafferty +3 more
2025bioRxiv0 citations
Semantic Scholar
Uninephrectomy and class II PI3K‐C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice
Samira Alliouachene, J. Kieswich, B. Bilanges, K. McCafferty +3 more
2020American Journal of Transplantation0 citations Open access
Semantic Scholar
FP473DOES PERITONEAL DIALYSIS VINTAGE AFFECT RELATIVE LEUCOCYTE TELOMERE LENGTH; A NOVEL BIOMARKER OF AGEING?
V. Muthuppalaniappan, J. Kieswich, K. McCafferty, M. Yaqoob
20180 citations Open access
Semantic Scholar
TITLE: eNAMPT-monomer plays an important role in development of experimental diabetes in mice and represents a potential target for treatment of type 2 diabetes
J. Kieswich, Sophie R. Sayers, M. Silvestre, S. Harwood +3 more
20160 citations
Semantic Scholar
eNAMPT-monomer plays a critical role in pathophysiology of experimental diabetes and represents a novel target for treatment of type 2 diabetes
J. Kieswich, M. Silvestre, S. Harwood, M. Yaqoob +1 more
20150 citations
Semantic Scholar
The effect of uraemia on the duration of arrhythmias in the context of cardioprotective ischaemic conditioning strategies
K. McCafferty, Conor J. Byrne, J. Kieswich, M. Raftery +2 more
2014Heart Asia0 citations Open access
Semantic Scholar
Response to Letter Regarding Article, “Ischemic Conditioning Protects the Uremic Heart in a Rodent Model of Myocardial Infarction”
K. McCafferty, Conor J. Byrne, J. Kieswich, S. Harwood +4 more
20120 citations Open access
Semantic Scholar
Thiamine protects the kidney against the injury and dysfunction caused by ischaemia reperfusion by multiple mechanisms
S. Memon, J. Kieswich, D. A. Allen, A. James +10 more
20100 citations
Semantic Scholar
Abstract 4841: The Impact of Chronic Uremia on Ichemic Preconditioning of the Myocardium
K. McCafferty, Conor J. Byrne, J. Kieswich, Magdi M. Yaqoob
2009Circulation0 citations
Semantic Scholar
IκB kinase inhibitor attenuates sepsis-induced cardiac dysfunction in mice with chronic kidney disease
Jian-Min Chen, J. Kieswich, F. Chiazza, A. Moyes +11 more
0 citations
Semantic Scholar

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