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J. Laragh · SciRah

Researcher profile · Semantic Scholar

J. Laragh

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J. Laragh — researcher profile on SciRah

h-index: 120
Works: 821
Citations: 61K

Most-cited papers

Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
S. Julius, S. Kjeldsen, M. Weber, H. Brunner +10 more
2004The Lancet2,566 citations
Semantic Scholar
Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial.
M. Weber, S. Julius, S. Kjeldsen, Hans R. Brunner +10 more
2004The Lancet615 citations
Semantic Scholar
Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: an analysis of findings from the VALUE trial
A. Zanchetti, S. Julius, S. Kjeldsen, G. Mcinnes +14 more
2006Journal of Hypertension175 citations
Semantic Scholar
Role of the Kidney in Congestive Heart Failure
S. Ljungman, J. Laragh, R. Cody
2012Drugs155 citations
Semantic Scholar
Aliskiren, the first renin inhibitor for treating hypertension: reactive renin secretion may limit its effectiveness.
J. Sealey, J. Laragh
2007American Journal of Hypertension155 citations
Semantic Scholar
The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) Trial: Outcomes in Patients Receiving Monotherapy
S. Julius, M. Weber, S. Kjeldsen, G. McInnes +16 more
2006HYPERTENSION153 citations Open access
Semantic Scholar
The plasma renin test reveals the contribution of body sodium-volume content (V) and renin-angiotensin (R) vasoconstriction to long-term blood pressure.
J. Laragh, J. Sealey
2011American Journal of Hypertension135 citations Open access
Semantic Scholar
Plasma Renin test-guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trial.
B. Egan, J. Basile, S. Rehman, P. B. Davis +7 more
2009American Journal of Hypertension126 citations
Semantic Scholar
Left ventricular mass change during treatment and outcome in patients with essential hypertension.
M. Koren, Roy J. Ulin, A. Koren, J. Laragh +1 more
2002American Journal of Hypertension125 citations Open access
Semantic Scholar
Plasma renin activity levels in hypertensive persons: their wide range and lack of suppression in diabetic and in most elderly patients.
M. Alderman, H. Cohen, J. Sealey, J. Laragh
2004American Journal of Hypertension124 citations Open access
Semantic Scholar
Management of hypertensive crises: the scientific basis for treatment decisions.
J. Blumenfeld, J. Laragh
2001American Journal of Hypertension117 citations Open access
Semantic Scholar
Frontiers in Hypertension Research
J. Laragh, F. Bühler, D. Seldin, Usv Laboratories
2011Springer: New York91 citations Open access
Semantic Scholar
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.
J. Laragh
2001American Journal of Hypertension91 citations
Semantic Scholar
Characteristics of 15314 Hypertensive Patients at High Coronary Risk. The VALUE Trial
S. Kjeldsen, S. Julius, H. Brunner, L. Hansson +7 more
200190 citations Open access
Semantic Scholar
Possible role of increased blood viscosity in the hemodynamics of systemic hypertension.
R. B. Devereux, D. Case, M. Alderman, T. Pickering +2 more
2000American Journal of Cardiology90 citations Open access
Semantic Scholar
Relevance of the plasma renin hormonal control system that regulates blood pressure and sodium balance for correctly treating hypertension and for evaluating ALLHAT.
J. Laragh, J. Sealey
2003American Journal of Hypertension87 citations
Semantic Scholar
VALUE trial: Long-term blood pressure trends in 13,449 patients with hypertension and high cardiovascular risk.
S. Julius, S. Kjeldsen, H. Brunner, L. Hansson +8 more
2003American Journal of Hypertension78 citations
Semantic Scholar
Beyond hypertension: Toward guidelines for cardiovascular risk reduction
M. Volpe, M. Alderman, C. Furberg, R. Jackson +4 more
200467 citations
Semantic Scholar
Aliskiren fails to lower blood pressure in patients who have either low PRA levels or whose PRA falls insufficiently or reactively rises.
J. Sealey, J. Laragh
2009American Journal of Hypertension62 citations
Semantic Scholar
Pressor responses to antihypertensive drug types.
M. Alderman, H. Cohen, J. Sealey, J. Laragh
2010American Journal of Hypertension61 citations
Semantic Scholar
ETHACRYNIC ACID 48-hour period of drug administration to eight
P. Cannon, Henry 0. Heineniann, W. B. Stason, J. Laragh
200560 citations
Semantic Scholar
Value Trial: long-term blood pressure trends In 13449 patients with hypertension and high cardiovascular risk
S. Julius, S. E. Kjeisen, H. Brunner, L. Hansson +8 more
200456 citations Open access
Semantic Scholar
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.
J. Laragh
2001American Journal of Hypertension50 citations Open access
Semantic Scholar
Low renin hypertensive states: perspectives, unsolved problems, future research.
R. Gordon, J. Laragh, J. Funder
2005Trends in endocrinology and metabolism48 citations
Semantic Scholar
Abstract, closing summary, and table of contents for Laragh's 25 lessons in pathophysiology and 12 clinical pearls for treating hypertension.
J. Laragh
2001American Journal of Hypertension42 citations
Semantic Scholar
Enduring direct association of baseline plasma renin activity with all-cause and cardiovascular mortality in hypertensive patients.
Maday C Gonzalez, H. Cohen, J. Sealey, J. Laragh +1 more
2011American Journal of Hypertension37 citations
Semantic Scholar
K(+) depletion and the progression of hypertensive disease or heart failure. The pathogenic role of diuretic-induced aldosterone secretion.
J. Laragh, J. Sealey
2001HYPERTENSION36 citations
Semantic Scholar
Characteristics of 15,314 hypertensive patients at high coronary risk. The VALUE trial. The Valsartan Antihypertensive Long-term Use Evaluation.
S. Kjeldsen, S. Julius, H. Brunner, L. Hansson +7 more
2001Blood Pressure36 citations
Semantic Scholar
Hypertension guidelines: criteria that might make them more clinically useful: In reply:
M. Alderman, M. Volpe, C. Furberg, R. Jackson +4 more
200335 citations
Semantic Scholar
Renin-angiotensin system blockers may create more risk than reward for sodium-depleted cardiovascular patients with high plasma renin levels.
J. Sealey, M. Alderman, C. Furberg, J. Laragh
2013American Journal of Hypertension33 citations Open access
Semantic Scholar
Effects of angiotensin receptor blockers on ambulatory plasma Renin activity in healthy, normal subjects during unrestricted sodium intake.
Michael Jones, J. Sealey, J. Laragh
2007American Journal of Hypertension32 citations Open access
Semantic Scholar
Plasma renin activity in the emergency department and its independent association with acute myocardial infarction.
J. Blumenfeld, J. Sealey, M. Alderman, H. Cohen +3 more
2000American Journal of Hypertension32 citations
Semantic Scholar
Plasma renin activity (PRA) levels and antihypertensive drug use in a large healthcare system.
J. Sim, S. Bhandari, Jia-Xiao M. Shi, K. Kalantar-Zadeh +3 more
2012American Journal of Hypertension31 citations Open access
Semantic Scholar
A Feasibility Study of Bevacizumab Plus Dose-Dense Doxorubicin–Cyclophosphamide (AC) Followed by Nanoparticle Albumin–Bound Paclitaxel in Early-Stage Breast Cancer
H. McArthur, H. Rugo, B. Nulsen, Laura Hawks +29 more
2011Clinical Cancer Research29 citations Open access
Semantic Scholar
Hemodynamic Responses
M. Volpe, S. Atlas, R. Sosa, D. Marion +3 more
200529 citations
Semantic Scholar
The VALUE Trial
S. Julius, S. Kjeldsen, H. Brunner, Steffan Enkman +8 more
200528 citations
Semantic Scholar
Myocardial function and geometry in hypertensive subjects with low levels of afterload.
G. Aurigemma, R. Devereux, G. de Simone, M. Roman +4 more
2002American Heart Journal28 citations
Semantic Scholar
Optimal resources for the examination and endovascular treatment of the peripheral and visceral vascular systems. AHA Intercouncil Report on Peripheral and Visceral Angiographic and Interventional Laboratories.
J. Cardella, W. Casarella, J. Deweese, G. Dorros +9 more
2003Journal of Vascular and Interventional Radiology27 citations
Semantic Scholar
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.
J. Laragh
2001American Journal of Hypertension24 citations
Semantic Scholar
Laragh's Lessons in Renin System Pathophysiology for Treating Hypertension and Its Fatal Cardiovascular Consequences
J. Laragh
200223 citations
Semantic Scholar
"Effective" plasma renin activity: a derived measure for assessing residual plasma renin activity in patients taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers.
J. Sealey, D. Parra, Robert S. Rosenstein, J. Laragh
2010HYPERTENSION20 citations Open access
Semantic Scholar
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.
J. Laragh
2001American Journal of Hypertension19 citations
Semantic Scholar
Nitric oxide synthase inhibition accelerates the pressor response to low-dose angiotensin II, exacerbates target organ damage, and induces renin escape.
Lu-Fei Hu, J. Sealey, Rong Chen, Ying Zhou +4 more
2004American Journal of Hypertension17 citations
Semantic Scholar
Acute vascular effects of the angiotensin II receptor antagonist olmesartan in normal subjects: relation to the renin-aldosterone system.
L. Resnick, D. Catanzaro, J. Sealey, J. Laragh
2004American Journal of Hypertension16 citations Open access
Semantic Scholar
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.
J. Laragh
2001American Journal of Hypertension16 citations
Semantic Scholar
Prorenin cryoactivation as a possible cause of normal renin levels in patients with primary aldosteronism.
J. Sealey, J. Blumenfeld, J. Laragh
2005Journal of Hypertension15 citations
Semantic Scholar
Primary and Secondary Hypertension
J. Blumenfeld, Frank Liu, J. Laragh
201211 citations
Semantic Scholar
Sodium depletion in patients in clinical trials may account for the increased cardiovascular risk of dual blockade of the renin-angiotensin system
J. Laragh, J. Sealey
2013British medical journal6 citations
Semantic Scholar
The renin system and atrial natriuretic hormone in congestive heart failure.
J. Laragh, Robert J. Cody, Andrew B. Covit, S. A. Atlas
2009Acta medica Scandinavica. Supplementum6 citations
Semantic Scholar
Review course: continuedLaragh’s lessons in pathophysiology and clinical pearls for treating hypertension1
J. Laragh
20016 citations
Semantic Scholar

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J. Sealey×19
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S. Julius×9
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A. Zanchetti×9
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M. Alderman×9
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M. Weber — researcher profile on SciRah

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H. Brunner — researcher profile on SciRah

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S. Ekman — researcher profile on SciRah

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L. Hansson — researcher profile on SciRah

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S. Kjeldsen — researcher profile on SciRah

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G. Mcinnes — researcher profile on SciRah

Beverly A. Smith×5

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Beverly A. Smith — researcher profile on SciRah

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