Researcher profile · Semantic Scholar

T. Karoli

h-index: 16
Works: 29
Citations: 1,086

Most-cited papers

PI-88 and novel heparan sulfate mimetics inhibit angiogenesis.
V. Ferro, K. Dredge, Li-Gong Liu, E. Hammond +7 more
2007Seminars in Thrombosis and Hemostasis144 citations
Semantic Scholar
Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria
M. Blaskovich, Karl A. Hansford, Yujing Gong, M. Butler +28 more
2018Nature Communications129 citations Open access
Semantic Scholar
Discovery of PG545: a highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis.
V. Ferro, Li-Gong Liu, K. Johnstone, Norbert Wimmer +10 more
2012Journal of Medicinal Chemistry118 citations Open access
Semantic Scholar
Clostridium difficile Drug Pipeline: Challenges in Discovery and Development of New Agents
Angie M. Jarrad, T. Karoli, M. Blaskovich, D. Lyras +1 more
2015Journal of Medicinal Chemistry89 citations Open access
Semantic Scholar
Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88).
T. Karoli, Li-Gong Liu, Jon K. Fairweather, E. Hammond +6 more
2005Journal of Medicinal Chemistry89 citations Open access
Semantic Scholar
Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.
K. Johnstone, T. Karoli, Li-Gong Liu, K. Dredge +13 more
2010Journal of Medicinal Chemistry71 citations Open access
Semantic Scholar
A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virus.
Maria Ekblad, B. Adamiak, T. Bergstrom, K. Johnstone +4 more
2010Antiviral Research67 citations
Semantic Scholar
Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis
Angie M. Jarrad, A. Debnath, Y. Miyamoto, Karl A. Hansford +7 more
2016European journal of medicinal chemistry57 citations Open access
Semantic Scholar
Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites
Angie M. Jarrad, T. Karoli, A. Debnath, Yen-Tay Chin +10 more
2015European journal of medicinal chemistry48 citations Open access
Semantic Scholar
Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors
E. Hammond, N. Haynes, C. Cullinane, T. Brennan +7 more
2018Journal of Immunotherapy for Cancer42 citations Open access
Semantic Scholar
Identification of antitubercular benzothiazinone compounds by ligand-based design.
T. Karoli, B. Becker, J. Zuegg, U. Möllmann +3 more
2012Journal of Medicinal Chemistry42 citations
Semantic Scholar
Structure aided design of chimeric antibiotics.
T. Karoli, S. Mamidyala, J. Zuegg, S. Fry +7 more
2012Bioorganic & Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Synthesis of essramycin and comparison of its antibacterial activity.
Ernest H L Tee, T. Karoli, Soumya Ramu, Johnny X. Huang +2 more
2010Journal of Natural Products29 citations
Semantic Scholar
Detection and Investigation of Eagle Effect Resistance to Vancomycin in Clostridium difficile With an ATP-Bioluminescence Assay
Angie M. Jarrad, M. Blaskovich, A. Prasetyoputri, T. Karoli +2 more
2018Frontiers in Microbiology25 citations Open access
Semantic Scholar
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity
Angie M. Jarrad, Wei-Ang Chee, A. Debnath, Hye Jee Hahn +11 more
2018Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Improved Immunoassay Sensitivity in Serum as a Result of Polymer-Entrapped Quantum Dots: 'Papaya Particles'.
A. Ranzoni, Anniek den Hamer, T. Karoli, Joseph A. Buechler +1 more
2015Analytical Chemistry17 citations
Semantic Scholar
The synthesis of phosphorylated disaccharide components of the extracellular phosphomannan of Pichia (Hansenula) holstii NRRL Y-2448.
Jon K. Fairweather, T. Karoli, V. Ferro
2004Bioorganic & Medicinal Chemistry15 citations
Semantic Scholar
Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides.
Li-Gong Liu, Ian Bytheway, T. Karoli, Jon K. Fairweather +3 more
2008Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Synthesis and activity of analogues of the isoleucyl tRNA synthetase inhibitor SB-203207.
C. Crasto, A. K. Forrest, T. Karoli, D. March +7 more
2003Bioorganic & Medicinal Chemistry12 citations
Semantic Scholar
Synthesis of Disaccharides Containing 6-Deoxy-α-L-talose as Potential Heparan Sulfate Mimetics
Jon K. Fairweather, Li-Gong Liu, T. Karoli, V. Ferro
2012Molecules8 citations Open access
Semantic Scholar
Synthesis of a heparan sulfate mimetic disaccharide with a conformationally locked residue from a common intermediate.
Jon K. Fairweather, T. Karoli, Li-Gong Liu, Ian Bytheway +1 more
2009Carbohydrate Research6 citations Open access
Semantic Scholar
2-Hydroxy-4-oxohenicosan-1-yl Acetate. Its Presence in Avocado and its Simple Chemistry
R. Carman, A. R. Duffield, P. Handley, T. Karoli
20004 citations
Semantic Scholar
A further synthesis of an analogue of the antifungal/antiherbivore lipid from avocado
R. Carman, T. Karoli
19984 citations
Semantic Scholar
Halogenated Terpenoids. XXIX The 1-Bromo 1-Bromomethyl Cyclohexyl System
Douglas J. Brecknell, R. Carman, R. Edwards, Karl A. Hansford +2 more
19972 citations
Semantic Scholar
Preparation of sulfated oligosaccharide derivatives as inhibitors of heparan sulfate-binding proteins
V. Ferro, T. Karoli, Li-Gong Liu, P. Handley +3 more
20090 citations
Semantic Scholar
Multi‐Component Assembly of the Bicyclic Core Associated with the tRNA Synthetase Inhibitors SB‐203207 and SB‐203208. Application to the Synthesis of Biologically Active Analogues.
M. Banwell, C. Crasto, C. Easton, T. Karoli +6 more
20020 citations
Semantic Scholar
A Further Synthesis of an Analogue of the Antifungal/Antiherbivore Lipid from Avocado.
R. Carman, T. Karoli
19990 citations
Semantic Scholar
Halogenated Terpenoids. XXX. The Bromocamphorenic Acids and the Dibromocampholides, and their Fomation from α,α-Dibromocamphor
R. Carman, T. Karoli, Brian N. Venzke
19980 citations
Semantic Scholar
The chemistry of the avocado antifungal
T. Karoli
19970 citations
Semantic Scholar

×6

Cai-Ping Li×5

Soumya Ramu×5