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T. Hansel · SciRah

Researcher profile · Semantic Scholar

T. Hansel

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T. Hansel — researcher profile on SciRah

h-index: 47
Works: 156
Citations: 10K

Most-cited papers

The safety and side effects of monoclonal antibodies
T. Hansel, H. Kropshofer, T. Singer, J. Mitchell +1 more
2010Nature reviews. Drug discovery1,098 citations
Semantic Scholar
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.
P. Flood-Page, C. Swenson, I. Faiferman, J. Matthews +7 more
2007American Journal of Respiratory and Critical Care Medicine733 citations
Semantic Scholar
Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
R. Pettipher, T. Hansel, R. Armer
2007Nature reviews. Drug discovery324 citations
Semantic Scholar
COPD-related morbidity and mortality after smoking cessation: status of the evidence
N. Godtfredsen, Tai-Hing Lam, T. Hansel, M. Leon +5 more
2008European Respiratory Journal290 citations Open access
Semantic Scholar
The Effects of a Monoclonal Antibody Directed against Tumor Necrosis Factor-α in Asthma
E. Erin, B. Leaker, G. C. Nicholson, A. J. Tan +8 more
2006247 citations
Semantic Scholar
Biomarkers for Acute Respiratory Distress syndrome and prospects for personalised medicine
S. Spadaro, Mirae Park, C. Turrini, Tanushree Tunstall +7 more
2019Journal of Inflammation228 citations Open access
Semantic Scholar
Airway eosinophilia in children with severe asthma: predictive values of noninvasive tests.
C. Lex, F. Ferreira, A. Zacharasiewicz, A. Nicholson +5 more
2006American Journal of Respiratory and Critical Care Medicine170 citations
Semantic Scholar
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection
M. Habibi, R. Thwaites, Meiping Chang, A. Jóźwik +13 more
2020Science167 citations Open access
Semantic Scholar
Microbes and mucosal immune responses in asthma.
T. Hansel, S. Johnston, P. Openshaw
2013The Lancet152 citations Open access
Semantic Scholar
The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma.
E. Erin, B. Leaker, G. C. Nicholson, A. J. Tan +8 more
2006American Journal of Respiratory and Critical Care Medicine131 citations
Semantic Scholar
Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza
J. Dunning, Simon Blankley, Long-Ho T. Ang, M. Cox +48 more
2018Nature Immunology128 citations Open access
Semantic Scholar
A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)
T. Hansel, Tanushree Tunstall, M. Trujillo‐Torralbo, B. Shamji +22 more
2017EBioMedicine121 citations Open access
Semantic Scholar
New drugs for exacerbations of chronic obstructive pulmonary disease.
T. Hansel, P. Barnes
2009The Lancet113 citations
Semantic Scholar
Reduced Nasal Viral Load and IFN Responses in Infants with Respiratory Syncytial Virus Bronchiolitis and Respiratory Failure
R. Thwaites, M. Coates, K. Ito, M. Ghazaly +9 more
2018American Journal of Respiratory and Critical Care Medicine107 citations Open access
Semantic Scholar
Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes.
G. Scadding, M. Calderón, V. Bellido, G. K. Koed +8 more
2012JIM - Journal of Immunological Methods98 citations
Semantic Scholar
Safety of regadenoson, an adenosine A2A receptor agonist for myocardial perfusion imaging, in mild asthma and moderate asthma patients: A randomized, double-blind, placebo-controlled trial
B. Leaker, B. Oconnor, T. Hansel, P. Barnes +3 more
2008Journal of Nuclear Cardiology92 citations
Semantic Scholar
Mucosal Type 2 Innate Lymphoid Cells Are a Key Component of the Allergic Response to Aeroallergens
J. Dhariwal, A. Cameron, M. Trujillo‐Torralbo, A. del Rosario +9 more
2017American Journal of Respiratory and Critical Care Medicine78 citations Open access
Semantic Scholar
The nasal mucosal late allergic reaction to grass pollen involves type 2 inflammation (IL-5 and IL-13), the inflammasome (IL-1β), and complement
B. Leaker, V. Malkov, R. Mogg, M. Ruddy +10 more
2016Mucosal Immunology72 citations Open access
Semantic Scholar
A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid.
B. Chawes, M. Edwards, B. Shamji, C. Walker +6 more
2010Journal of Allergy and Clinical Immunology67 citations
Semantic Scholar
Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
R. Thwaites, Hannah C. Jarvis, Nehmat Singh, Akhilesh Jha +8 more
2018Journal of Visualized Experiments64 citations Open access
Semantic Scholar
Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy.
N. Følsgaard, B. Chawes, M. Rasmussen, A. L. Bischoff +7 more
2012American Journal of Respiratory and Critical Care Medicine64 citations
Semantic Scholar
Smoking‐related emphysema is associated with idiopathic pulmonary fibrosis and rheumatoid lung
K. M. Antoniou, S. Walsh, D. Hansell, Michael Rubens +7 more
2013Respirology (Carlton South. Print)63 citations
Semantic Scholar
Non-specific interstitial pneumonia in cigarette smokers: a CT study
K. Marten, D. Milne, K. Antoniou, A. Nicholson +4 more
2009European Radiology62 citations Open access
Semantic Scholar
Time to diagnosis of tuberculosis is greater in older patients: a retrospective cohort review
A. Abbara, S. Collin, O. Kon, K. Buell +7 more
2019ERJ Open Research60 citations Open access
Semantic Scholar
A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist.
G. C. Nicholson, Rachel C. Tennant, D. Carpenter, H. Sarau +6 more
2007Pulmonary Pharmacology & Therapeutics57 citations
Semantic Scholar
IL-15 complexes induce NK cell and T cell responses independent of type I IFN signalling during rhinovirus infection
Annabelle Jayaraman, D. Jackson, S. Message, R. Pearson +11 more
2014Mucosal Immunology55 citations Open access
Semantic Scholar
The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge.
G. C. Nicholson, H. Kariyawasam, A. J. Tan, J. Hohlfeld +9 more
2011Journal of Allergy and Clinical Immunology55 citations
Semantic Scholar
Does sputum eosinophilia predict the response to systemic corticosteroids in children with difficult asthma?
C. Lex, G. Jenkins, N. Wilson, A. Zacharasiewicz +4 more
2007Pediatric Pulmonology43 citations
Semantic Scholar
Nasosorption as a Minimally Invasive Sampling Procedure: Mucosal Viral Load and Inflammation in Primary RSV Bronchiolitis
R. Thwaites, K. Ito, Jasmine M. S. Chingono, M. Coates +8 more
2017Journal of Infectious Diseases42 citations Open access
Semantic Scholar
A multinational, 12-week, randomized study comparing the efficacy and tolerability of ciclesonide and budesonide in patients with asthma.
T. Hansel, O. Bénézet, H. Kafé, H. Ponitz +3 more
2006Clinical Therapeutics42 citations
Semantic Scholar
Antagonists of the prostaglandin D2 receptor CRTH2.
R. Pettipher, T. Hansel
2008Drug News and Perspectives40 citations
Semantic Scholar
Medical Swab Analysis Using Desorption Electrospray Ionization Mass Spectrometry: A Noninvasive Approach for Mucosal Diagnostics.
Pamela Pruski, D. MacIntyre, H. Lewis, P. Inglese +5 more
2017Analytical Chemistry39 citations
Semantic Scholar
Variability of bronchial inflammation in chronic obstructive pulmonary disease: implications for study design
E. Gamble, Y. Qiu, Duo-Lao Wang, Jie Zhu +8 more
2006European Respiratory Journal39 citations Open access
Semantic Scholar
Effects of a reversible β‐tryptase and trypsin inhibitor (RWJ‐58643) on nasal allergic responses
E. Erin, B. R. Leaker, A. Zacharasiewicz, L. A. Higgins +7 more
2006Clinical and Experimental Allergy39 citations
Semantic Scholar
Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants.
E. Erin, G. Jenkins, O. Kon, A. Zacharasiewicz +9 more
2008American Journal of Respiratory and Critical Care Medicine37 citations
Semantic Scholar
Increased nasal mucosal interferon and CCL13 response to a TLR7/8 agonist in asthma and allergic rhinitis.
Akhilesh Jha, R. Thwaites, Tanushree Tunstall, O. Kon +3 more
2020Journal of Allergy and Clinical Immunology36 citations Open access
Semantic Scholar
Smoking cessation in COPD causes a transient improvement in spirometry and decreases micronodules on high-resolution CT imaging.
J. Dhariwal, Rachel C. Tennant, D. Hansell, J. Westwick +6 more
2014Chest34 citations Open access
Semantic Scholar
Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study.
E. Erin, A. Zacharasiewicz, G. C. Nicholson, A. J. Tan +6 more
2008Chest34 citations
Semantic Scholar
Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza
Akhilesh Jha, J. Dunning, Tanushree Tunstall, R. Thwaites +5 more
2019European Respiratory Journal31 citations Open access
Semantic Scholar
Pulmonary Innate Lymphoid Cell Responses during Rhinovirus-induced Asthma Exacerbations In Vivo: A Clinical Trial.
J. Dhariwal, A. Cameron, Ernie H. C. Wong, M. Paulsen +17 more
2021American Journal of Respiratory and Critical Care Medicine30 citations Open access
Semantic Scholar
Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates.
H. Wolsk, N. Følsgaard, Sune Birch, S. Brix +6 more
2016Journal of Infectious Diseases24 citations Open access
Semantic Scholar
An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics
D. M. Reed, K. Paschalaki, R. Starke, N. Mohamed +11 more
2015The FASEB Journal24 citations
Semantic Scholar
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (vol 19, pg 625, 2018)
J. Dunning, Simon Blankley, Long-Ho T. Ang, M. Cox +49 more
201919 citations
Semantic Scholar
Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness
J. Dhariwal, J. Kitson, R.E. Jones, G. C. Nicholson +9 more
2015PLoS ONE17 citations Open access
Semantic Scholar
A simple whole blood bioassay detects cytokine responses to anti-CD28SA and anti-CD52 antibodies.
Lucy K. Bailey, Laura Moreno, T. Manigold, Sebastian Krasniqi +6 more
2013Journal of pharmacological and toxicological methods17 citations
Semantic Scholar
Effect of Different Interferonα2 Preparations on IP10 and ET-1 Release from Human Lung Cells
R. Badiger, J. Mitchell, H. Gashaw, Neil A. Galloway-Phillipps +5 more
2012PLoS ONE17 citations Open access
Semantic Scholar
Oxidative/nitrosative stress selectively altered A2B adenosine receptors in chronic obstructive pulmonary disease
K. Varani, G. Caramori, F. Vincenzi, A. Tosi +12 more
2010The FASEB Journal17 citations
Semantic Scholar
New drug therapies for COPD.
Clare L Ross, T. Hansel
2014Clinics in Chest Medicine15 citations
Semantic Scholar
Induction of innate cytokine responses by respiratory mucosal challenge with R848 in zebrafish, mice, and humans
F. Progatzky, Akhilesh Jha, Madina Wane, R. Thwaites +7 more
2019Journal of Allergy and Clinical Immunology14 citations Open access
Semantic Scholar
Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance
G. Scaramuzzo, F. Nucera, Alessio Asmundo, R. Messina +15 more
2023Journal of Inflammation13 citations Open access
Semantic Scholar

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O. Kon×16
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R. Thwaites×10
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Tanushree Tunstall×9

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S. Johnston — researcher profile on SciRah

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E. Erin — researcher profile on SciRah

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A. Zacharasiewicz×5

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A. Zacharasiewicz — researcher profile on SciRah

Rachel C. Tennant×5

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Rachel C. Tennant — researcher profile on SciRah