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T. Nishikimi · SciRah

Researcher profile · Semantic Scholar

T. Nishikimi

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T. Nishikimi — researcher profile on SciRah

h-index: 46
Works: 251
Citations: 9,380

Most-cited papers

Atrial and brain natriuretic peptides: Hormones secreted from the heart.
Y. Nakagawa, T. Nishikimi, K. Kuwahara
2019Peptides220 citations Open access
Semantic Scholar
Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides.
T. Nishikimi, K. Kuwahara, K. Nakao
2011Journal of Cardiology212 citations Open access
Semantic Scholar
Reciprocal expression of MRTF‐A and myocardin is crucial for pathological vascular remodelling in mice
Takeya Minami, K. Kuwahara, Y. Nakagawa, M. Takaoka +18 more
2012EMBO Journal102 citations Open access
Semantic Scholar
Transcriptional regulation of the fetal cardiac gene program.
K. Kuwahara, T. Nishikimi, K. Nakao
2012Journal of Pharmacological Sciences99 citations Open access
Semantic Scholar
Greater expression of inflammatory cytokines, adrenomedullin, and natriuretic peptide receptor-C in epicardial adipose tissue in coronary artery disease.
I. Shibasaki, T. Nishikimi, Y. Mochizuki, Y. Yamada +7 more
2010Regulatory Peptides75 citations
Semantic Scholar
Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts
Yoshihiro Kuwabara, K. Kuwahara, M. Takano, Hideyuki Kinoshita +13 more
2013Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease73 citations Open access
Semantic Scholar
Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity
K. Nakao, K. Kuwahara, T. Nishikimi, Y. Nakagawa +15 more
2017HYPERTENSION68 citations Open access
Semantic Scholar
Potential pitfalls when interpreting plasma BNP levels in heart failure practice.
T. Nishikimi, Y. Nakagawa
2021Journal of Cardiology64 citations Open access
Semantic Scholar
Direct Immunochemiluminescent Assay for proBNP and Total BNP in Human Plasma proBNP and Total BNP Levels in Normal and Heart Failure
T. Nishikimi, Hiroyuki Okamoto, M. Nakamura, Naoko Ogawa +13 more
2013PLoS ONE64 citations Open access
Semantic Scholar
The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure
T. Nishikimi, M. Ikeda, Y. Takeda, T. Ishimitsu +6 more
2011Heart63 citations
Semantic Scholar
MiR30‐GALNT1/2 Axis‐Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts
Y. Nakagawa, T. Nishikimi, K. Kuwahara, Aoi Fujishima +17 more
2017Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease57 citations Open access
Semantic Scholar
Adrenomedullin as a Biomarker of Heart Failure.
T. Nishikimi, Y. Nakagawa
2018Heart Failure Clinics44 citations
Semantic Scholar
Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites.
T. Nishikimi, Y. Nakagawa, N. Minamino, M. Ikeda +14 more
2015American Journal of Physiology. Regulatory Integrative and Comparative Physiology44 citations
Semantic Scholar
Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice.
T. Nishikimi, Chikako Inaba-Iemura, Kimihiko Ishimura, Kazuyoshi Tadokoro +8 more
2009Regulatory Peptides44 citations
Semantic Scholar
Adrenomedullin in cardiovascular disease: a useful biomarker, its pathological roles and therapeutic application.
T. Nishikimi, K. Kuwahara, Y. Nakagawa, K. Kangawa +1 more
2013Current protein and peptide science40 citations
Semantic Scholar
B-Type Natriuretic Peptide (BNP) Revisited—Is BNP Still a Biomarker for Heart Failure in the Angiotensin Receptor/Neprilysin Inhibitor Era?
T. Nishikimi, Y. Nakagawa
2022Biology34 citations Open access
Semantic Scholar
CNP, the Third Natriuretic Peptide: Its Biology and Significance to the Cardiovascular System
Y. Nakagawa, T. Nishikimi
2022Biology29 citations Open access
Semantic Scholar
Cutting Edge of Brain Natriuretic Peptide (BNP) Research - The Diversity of BNP Immunoreactivity and Its Clinical Relevance.
K. Kuwahara, Y. Nakagawa, T. Nishikimi
2018Circulation Journal29 citations Open access
Semantic Scholar
Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy
S. Yasuno, K. Kuwahara, Hideyuki Kinoshita, Chinatsu Yamada +7 more
2013British Journal of Pharmacology29 citations Open access
Semantic Scholar
Beneficial effects of a combination of Rho-kinase inhibitor and ACE inhibitor on tubulointerstitial fibrosis induced by unilateral ureteral obstruction
Y. Takeda, T. Nishikimi, K. Akimoto, H. Matsuoka +1 more
2010Hypertension Research28 citations Open access
Semantic Scholar
Japanese-Western consensus meeting on biomarkers.
A. Maisel, K. Nakao, P. Ponikowski, W. Peacock +11 more
2011International Heart Journal25 citations Open access
Semantic Scholar
Change in the NT‐proBNP/Mature BNP Molar Ratio Precedes Worsening Renal Function in Patients With Acute Heart Failure: A Novel Predictor Candidate for Cardiorenal Syndrome
Hiroyuki Takahama, T. Nishikimi, S. Takashio, Tomohiro Hayashi +16 more
2019Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease24 citations Open access
Semantic Scholar
Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure.
Yuko Yamada, Hideyuki Kinoshita, K. Kuwahara, Y. Nakagawa +17 more
2014Cardiovascular Research24 citations Open access
Semantic Scholar
MANGANESE deficiency.
M. Oette, M. Stone, H. Scholl, P. Issa +175 more
2022Journal of the American Veterinary Medical Association20 citations Open access
Semantic Scholar
Complexity of molecular forms of B-type natriuretic peptide in heart failure
T. Nishikimi, K. Kuwahara, Y. Nakagawa, K. Kangawa +2 more
2012Heart20 citations
Semantic Scholar
Abstract 052: Epicardial-derived Adrenomedullin Drives Cardiac Hyperplasia During Embryogenesis
S. Wetzel-Strong, Man-Yu Li, T. Nishikimi, K. Caron
201319 citations
Semantic Scholar
Effect of heart failure and malnutrition, alone and in combination, on rehabilitation effectiveness in patients with hip fracture.
Y. Tamamura, M. Matsuura, Sumiko Shiba, T. Nishikimi
2021Clinical Nutrition ESPEN17 citations Open access
Semantic Scholar
Ratio of pro-B-type natriuretic peptide (BNP) to total BNP is decreased in mild, but not severe, acute decompensated heart failure patients: A novel compensatory mechanism for acute heart failure.
Hiroyuki Takahama, S. Takashio, T. Nishikimi, Tomohiro Hayashi +11 more
2018International Journal of Cardiology17 citations
Semantic Scholar
The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy.
Chinatsu Yamada, K. Kuwahara, M. Yamazaki, Y. Nakagawa +13 more
2016Cardiovascular Research16 citations Open access
Semantic Scholar
Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes.
L. Hata, Masao Murakami, K. Kuwahara, Y. Nakagawa +12 more
2011Journal of Molecular and Cellular Cardiology14 citations
Semantic Scholar
Heart failure assessed based on plasma B-type natriuretic peptide (BNP) levels negatively impacts activity of daily living in patients with hip fracture
Y. Tamamura, M. Matsuura, Sumiko Shiba, T. Nishikimi
2020PLoS ONE12 citations Open access
Semantic Scholar
NRSF-GNAO1 Pathway Contributes to the Regulation of Cardiac Ca2+ Homeostasis
H. Inazumi, K. Kuwahara, Y. Nakagawa, Yoshihiro Kuwabara +18 more
2021Circulation Research11 citations
Semantic Scholar
Diverse Molecular Forms of Plasma B-Type Natriuretic Peptide in Heart Failure
T. Nishikimi, N. Minamino, K. Nakao
2011Current Heart Failure Reports9 citations Open access
Semantic Scholar
Cardiac Peptides—Current Physiology, Pathophysiology, Biochemistry, Molecular Biology, and Clinical Application
T. Nishikimi, J. Kato
2022Biology7 citations Open access
Semantic Scholar
The Effects of Super-Flux (High Performance) Dialyzer on Plasma Glycosylated Pro-B-Type Natriuretic Peptide (proBNP) and Glycosylated N-Terminal proBNP in End-Stage Renal Disease Patients on Dialysis
Y. Nakagawa, T. Nishikimi, K. Kuwahara, S. Yasuno +13 more
2013BMC Pharmacology and Toxicology7 citations Open access
Semantic Scholar
Do plasma levels of brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) increase in diastolic dysfunction as well as in systolic dysfunction?
T. Nishikimi
2012Circulation Journal7 citations Open access
Semantic Scholar
The Relationship between the Severity of Constipation and Exercise Status in the Japanese Population according to Questionnaire Survey
Sumiko Shiba, Takuro Masunaga, Y. Tamamura, M. Matsuura +1 more
2022GastroHep6 citations Open access
Semantic Scholar
Does impaired processing of pro-B-type (or brain) natriuretic peptide cause decreased plasma BNP levels in obese heart failure patients?
T. Nishikimi, Y. Nakagawa
2019Annals of Translational Medicine6 citations Open access
Semantic Scholar
Longitudinal changes in late systolic cardiac load and serum NT-proBNP levels in healthy middle-aged Japanese men.
H. Tomiyama, T. Nishikimi, C. Matsumoto, K. Kimura +3 more
2015American Journal of Hypertension6 citations
Semantic Scholar
Effects of Banafine® , a fermented green banana-derived acidic glycoconjugate, on influenza vaccine antibody titer in elderly patients receiving gastrostomy tube feeding.
K. Horie, Md. Saddam Hossain, Yugweng Kim, Akiko Ishida +5 more
2021Journal of Food Science5 citations
Semantic Scholar
Superiority of proatrial natriuretic peptide in the prognostic power in patients with acute decompensated heart failure on hospital admission: comparison with B-type natriuretic peptide and other natriuretic peptide forms
S. Takashio, Hiroyuki Takahama, T. Nishikimi, Tomohiro Hayashi +14 more
2019Open Heart5 citations Open access
Semantic Scholar
Molecular ratio of mature B‐type natriuretic peptide in acute heart failure: an indicator for ventricular contractile recovery
Akihisa Kimura, Hiroyuki Takahama, T. Nishikimi, S. Takashio +7 more
2021ESC Heart Failure4 citations Open access
Semantic Scholar
TRPC3/6 as Potentially Novel Therapeutic Targets for The Treatment of Pulmonary Arterial Hypertension
Hideyuki Kinoshita, K. Kuwahara, Shigeki Kiyonaka, Y. Mori +6 more
20114 citations
Semantic Scholar
Effect of short-duration, limited rehabilitation on maintenance of the activities of daily living in patients with acute phase of COVID-19
Y. Tamamura, H. Yoshikawa, M. Matsuura, Makoto Kashio +3 more
2022Journal of Physical Therapy Science3 citations Open access
Semantic Scholar
[Clinical significance of BNP as a biomarker for cardiac disease--from a viewpoint of basic science and clinical aspect].
T. Nishikimi
2012Nihon rinsho. Japanese journal of clinical medicine3 citations
Semantic Scholar
Special Japanese-Western Consensus Meeting on Biomarkers Executive Summary
A. Maisel, K. Nakao, P. Ponikowski, W. Peacock +11 more
20113 citations
Semantic Scholar
Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report.
Y. Nakagawa, T. Nishikimi, Hiroshi Sakai, S. Ohno +6 more
2017Clinical Biochemistry2 citations
Semantic Scholar
Chapter 192 – Natriuretic Peptides
N. Minamino, T. Nishikimi
20132 citations
Semantic Scholar
The effects of super-flux (high performance) dialyzer on the plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-terminal proBNP in end-stage renal disease patients on dialysis
Y. Nakagawa, T. Nishikimi, N. Minamino, Chinatsu Yamada +9 more
2013BMC Pharmacology and Toxicology2 citations Open access
Semantic Scholar
Adrenomedullin in Heart Failure: Molecular Mechanism and Therapeutic Implication
T. Nishikimi, K. Nakao, K. Kangawa
20112 citations
Semantic Scholar

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Y. Nakagawa×29
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K. Kuwahara×22
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Hideyuki Kinoshita×16
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Yoshihiro Kuwabara

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