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B. Posocco · SciRah

Researcher profile · Semantic Scholar

B. Posocco

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B. Posocco — researcher profile on SciRah

h-index: 17
Works: 50
Citations: 765

Most-cited papers

Polysaccharides for the Delivery of Antitumor Drugs
B. Posocco, Eva Dreussi, Jacopo de Santa, G. Toffoli +7 more
2015Materials111 citations Open access
Semantic Scholar
Nanocarriers in cancer clinical practice: a pharmacokinetic issue.
L. Giodini, Francesco Lo Re, Davide Campagnol, E. Marangon +3 more
2017Nanomedicine : nanotechnology, biology, and medicine62 citations
Semantic Scholar
Development and Validation of a High-Performance Liquid Chromatography–Tandem Mass Spectrometry Method for the Simultaneous Determination of Irinotecan and Its Main Metabolites in Human Plasma and Its Application in a Clinical Pharmacokinetic Study
E. Marangon, B. Posocco, E. Mazzega, G. Toffoli
2015PLoS ONE47 citations Open access
Semantic Scholar
Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/MS method for clinical application
B. Posocco, Mauro Buzzo, A. S. Poetto, Marco Orleni +9 more
2020PLoS ONE41 citations Open access
Semantic Scholar
Genotype-guided dosing study of FOLFIRI plus bevacizumab in metastatic colorectal cancer patients
G. Toffoli, Manish R. Sharma, E. Marangon, B. Posocco +7 more
2016Clinical Cancer Research41 citations Open access
Semantic Scholar
Dried Blood Spot Technique Applied in Therapeutic Drug Monitoring of Anticancer Drugs: a Review on Conversion Methods to Correlate Plasma and Dried Blood Spot Concentrations
Valentina Iacuzzi, B. Posocco, Martina Zanchetta, S. Gagno +3 more
2021Pharmaceutical Research37 citations Open access
Semantic Scholar
Clinical impact of body mass index on palbociclib treatment outcomes and effect on exposure.
R. Roncato, E. Peruzzi, L. Gerratana, B. Posocco +13 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie32 citations Open access
Semantic Scholar
Development and validation of LC-MS/MS method for imatinib and norimatinib monitoring by finger-prick DBS in gastrointestinal stromal tumor patients
Valentina Iacuzzi, B. Posocco, Martina Zanchetta, M. Montico +8 more
2019PLoS ONE29 citations Open access
Semantic Scholar
An Integrated Pharmacological Counselling Approach to Guide Decision-Making in the Treatment with CDK4/6 Inhibitors for Metastatic Breast Cancer
R. Roncato, L. Gerratana, L. Palmero, S. Gagno +11 more
2022Frontiers in Pharmacology28 citations Open access
Semantic Scholar
A new dried blood spot LC-MS/MS method for therapeutic drug monitoring of palbociclib, ribociclib, and letrozole in patients with cancer.
Ariana Soledad Poetto, B. Posocco, S. Gagno, Marco Orleni +12 more
2021Journal of chromatography. B, Analytical technologies in the biomedical and life sciences23 citations Open access
Semantic Scholar
Analytical aspects of sunitinib and its geometric isomerism towards therapeutic drug monitoring in clinical routine
B. Posocco, Mauro Buzzo, L. Giodini, S. Crotti +5 more
2018Journal of Pharmaceutical and Biomedical Analysis23 citations Open access
Semantic Scholar
Mass spectrometry in the pharmacokinetic studies of anticancer natural products.
S. Crotti, B. Posocco, E. Marangon, D. Nitti +2 more
2017Mass spectrometry reviews (Print)23 citations
Semantic Scholar
LC-MS/MS Method for the Quantification of PARP Inhibitors Olaparib, Rucaparib and Niraparib in Human Plasma and Dried Blood Spot: Development, Validation and Clinical Validation for Therapeutic Drug Monitoring
Giovanni Canil, Marco Orleni, B. Posocco, S. Gagno +6 more
2023Pharmaceutics19 citations Open access
Semantic Scholar
An SPR investigation into the therapeutic drug monitoring of the anticancer drug imatinib with selective aptamers operating in human plasma.
Stefano Tartaggia, A. Meneghello, Ottavia Bellotto, A. S. Poetto +5 more
2021In Analysis19 citations
Semantic Scholar
Impact of ABCG2 and ABCB1 Polymorphisms on Imatinib Plasmatic Exposure: An Original Work and Meta-Analysis
C. Dalle Fratte, J. Polesel, S. Gagno, B. Posocco +8 more
2023International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
A rapid, simple and sensitive LC-MS/MS method for lenvatinib quantification in human plasma for therapeutic drug monitoring
Martina Zanchetta, Valentina Iacuzzi, B. Posocco, Giorgia Bortolin +9 more
2021PLoS ONE17 citations Open access
Semantic Scholar
A new high-performance liquid chromatography-tandem mass spectrometry method for the determination of paclitaxel and 6α-hydroxy-paclitaxel in human plasma: Development, validation and application in a clinical pharmacokinetic study
B. Posocco, Mauro Buzzo, Andrea Follegot, L. Giodini +3 more
2018PLoS ONE17 citations Open access
Semantic Scholar
A LC-MS/MS method for therapeutic drug monitoring of sorafenib, regorafenib and their active metabolites in patients with hepatocellular carcinoma.
Valentina Iacuzzi, Martina Zanchetta, S. Gagno, A. S. Poetto +6 more
2020Journal of Pharmaceutical and Biomedical Analysis16 citations Open access
Semantic Scholar
Association of ADME gene polymorphisms on toxicity to CDK4/6 inhibitors in patients with HR+ HER2- metastatic breast cancer.
E. Peruzzi, L. Gerratana, M. Montico, B. Posocco +10 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie15 citations Open access
Semantic Scholar
Development and validation of a selective SPR aptasensor for the detection of anticancer drug irinotecan in human plasma samples
A. Puşcaşu, Martina Zanchetta, B. Posocco, D. Bunka +2 more
2021Analytical and Bioanalytical Chemistry14 citations Open access
Semantic Scholar
A new high-performance liquid chromatography-tandem mass spectrometry method for the determination of sunitinib and N-desethyl sunitinib in human plasma: Light-induced isomerism overtaking towards therapeutic drug monitoring in clinical routine.
E. Marangon, Mauro Buzzo, B. Posocco, S. Gagno +6 more
2019Journal of Pharmaceutical and Biomedical Analysis13 citations Open access
Semantic Scholar
CYP2D6 and CYP2C8 pharmacogenetics and pharmacological interactions to predict imatinib plasmatic exposure in GIST patients
C. Dalle Fratte, S. Gagno, R. Roncato, J. Polesel +11 more
2022British Journal of Clinical Pharmacology12 citations Open access
Semantic Scholar
Cross-validation of a mass spectrometric-based method for the therapeutic drug monitoring of irinotecan: implementation of matrix-assisted laser desorption/ionization mass spectrometry in pharmacokinetic measurements
E. Calandra, B. Posocco, S. Crotti, E. Marangon +5 more
2016Analytical and Bioanalytical Chemistry11 citations
Semantic Scholar
Population pharmacokinetic modelling of imatinib in healthy subjects receiving a single dose of 400 mg
Yi-Han Chien, G. Würthwein, P. Zubiaur, B. Posocco +5 more
2022Cancer Chemotherapy and Pharmacology10 citations Open access
Semantic Scholar
Bioanalytical Methods for Poly(ADP-Ribose) Polymerase Inhibitor Quantification: A Review for Therapeutic Drug Monitoring
Marco Orleni, Giovanni Canil, B. Posocco, S. Gagno +1 more
2023Therapeutic Drug Monitoring9 citations Open access
Semantic Scholar
Matrix-Assisted Laser Desorption/Ionization, Nanostructure-Assisted Laser Desorption/Ionization and Carbon Nanohorns in the Detection of Antineoplastic Drugs. 1. The Cases of Irinotecan, Sunitinib and 6-Alpha-Hydroxy Paclitaxel
P. Traldi, E. Calandra, S. Crotti, M. Agostini +5 more
2014European Journal of Mass Spectrometry9 citations
Semantic Scholar
The Role of Gender Pharmacogenetics in the Personalization of Drug Treatment
E. Cecchin, B. Posocco, Silvia Mezzalira, M. Appetecchia +1 more
2023Journal of Pharmacology and Experimental Therapeutics7 citations Open access
Semantic Scholar
"A new LC-MS/MS method for the simultaneous quantification of abemaciclib, its main active metabolites M2 and M20, and letrozole for therapeutic drug monitoring".
Ariana Soledad Poetto, B. Posocco, Martina Zanchetta, S. Gagno +5 more
2022Journal of chromatography. B, Analytical technologies in the biomedical and life sciences7 citations
Semantic Scholar
Increased plasma imatinib exposure and toxicity in chronically treated GIST patients with SARS-CoV-2 infection: a case series
S. Gagno, B. Posocco, Marco Orleni, Eleonora Cecchin +7 more
2024Frontiers in Immunology5 citations Open access
Semantic Scholar
Therapeutic Monitoring of Palbociclib, Ribociclib, Abemaciclib, M2, M20, and Letrozole in Human Plasma: A Novel LC-MS/MS Method
B. Posocco, Martina Zanchetta, Marco Orleni, S. Gagno +7 more
2024Therapeutic Drug Monitoring5 citations Open access
Semantic Scholar
Exploring pharmacokinetic variability of palbociclib in HR+/HER2- metastatic breast cancer: a focus on age, renal function, and drug–gene interactions
E. Peruzzi, B. Posocco, L. Gerratana, M. Nuti +7 more
2024Frontiers in Pharmacology5 citations Open access
Semantic Scholar
The use of therapeutic drug monitoring to highlight an over-looked drug-drug interaction leading to imatinib treatment failure
S. Gagno, A. Buonadonna, C. Dalle Fratte, M. Guardascione +7 more
2023DARU Journal of Pharmaceutical Sciences5 citations Open access
Semantic Scholar
A fast and validated LC-MS/MS method to quantify lenvatinib in dried blood spot.
Martina Zanchetta, B. Posocco, S. Gagno, A. S. Poetto +5 more
2023Journal of Pharmaceutical and Biomedical Analysis5 citations
Semantic Scholar
Exceptional Chemotherapy Response in Metastatic Colorectal Cancer Associated With Hyper-Indel–Hypermutated Cancer Genome and Comutation of POLD1 and MLH1
Manish R. Sharma, J. Auman, N. Patel, J. Grilley-Olson +11 more
2017JCO Precision Oncology5 citations Open access
Semantic Scholar
Field-Assisted Paper Spray Mass Spectrometry for the Quantitative Evaluation of Imatinib Levels in Plasma
Sara D'Aronco, E. Calandra, S. Crotti, G. Toffoli +4 more
2016European Journal of Mass Spectrometry5 citations
Semantic Scholar
The development of a matrix-assisted laser desorption/ionization (MALDI)-based analytical method for determination of irinotecan levels in human plasma: preliminary results.
E. Calandra, S. Crotti, D. Nitti, Marco Roverso +5 more
2015Journal of Mass Spectrometry5 citations
Semantic Scholar
Imatinib and norimatinib therapeutic monitoring using dried blood spots: Analytical and clinical validation, and performance comparison of volumetric collection devices.
Marco Orleni, S. Gagno, Eleonora Cecchin, Marcella Montico +7 more
2025Journal of chromatography. B, Analytical technologies in the biomedical and life sciences4 citations
Semantic Scholar
Therapeutic drug monitoring and pharmacogenetics to tune imatinib exposure in gastrointestinal stromal tumor patients: hurdles and perspectives for clinical implementation.
S. Gagno, C. D. Fratte, B. Posocco, A. Buonadonna +4 more
2023Pharmacogenomics (London)4 citations Open access
Semantic Scholar
Field-assisted paper spray mass spectrometry for therapeutic drug monitoring: 1. the case of imatinib in plasma.
Sara D'Aronco, M. Dall'Armi, S. Crotti, E. Calandra +9 more
2017Journal of Mass Spectrometry4 citations
Semantic Scholar
Quantification of Letrozole, Palbociclib, Ribociclib, Abemaciclib, and Metabolites in Volumetric Dried Blood Spots: Development and Validation of an LC-MS/MS Method for Therapeutic Drug Monitoring
Eleonora Cecchin, Marco Orleni, S. Gagno, Marcella Montico +8 more
2024International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
LC-MS/MS Method for Therapeutic Drug Monitoring of Abiraterone, Darolutamide, Apalutamide, Enzalutamide, and Metabolites in Prostate Cancer Patients
B. Posocco, Diletta Pasin, Nicoletta De Cesaro, Alice Pivetta +12 more
2026International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
Clinical Validity of Imatinib Therapeutic Drug Monitoring in a Real-World Italian Cohort of Gastrointestinal Stromal Tumors and the Role of Patients’ Sex
S. Gagno, A. Buonadonna, Eleonora Cecchin, A. Fumagalli +7 more
2026Pharmaceutics0 citations Open access
Semantic Scholar
DPYD c.85T>C, DPYD c.496A>G, and DPYD c.2194G>A and severe toxicity to fluoropyrimidines in PREPARE and Alpe-DPD trials. An original study and meta-analysis.
E. De Mattia, J. Polesel, M. van der Lee, S. Bohringer +14 more
2026Pharmacological Research0 citations Open access
Semantic Scholar
IUC24414-80 Optimizing sunitinib therapy in mRCC through pharmacological counseling and early TDM integration
G. Bortolus, E. Cecchin, S. Gagno, B. Posocco +6 more
2025The Oncologist0 citations Open access
Semantic Scholar
78P The integration of TDM and PGx in patients with mRCC receiving sunitinib treatment
G. Bortolus, E. Cecchin, S. Gagno, B. Posocco +6 more
2025ESMO Open0 citations Open access
Semantic Scholar
P198 Applying TDM and PGx in mRCC patients treated with Sunitinib to customize drug dosing
G. Bortolus, E. Cecchin, S. Gagno, B. Posocco +5 more
2024European Urology Open Science0 citations Open access
Semantic Scholar
95P Implementation of TDM and PGx in mRCC patients treated with sunitinib to personalize drug dosing
G. Bortolus, E. Cecchin, S. Gagno, B. Posocco +5 more
2024ESMO Open0 citations Open access
Semantic Scholar
An alternative analytical method for the therapeutic drug monitoring of irinotecan : toward personalized medicine
B. Posocco, E. Calandra, E. Marangon, S. Crotti +3 more
20160 citations
Semantic Scholar
Mass Balance: An Old Concept for the New Challenges Proposed by Personalized Medicine
M. Grassi, Michela Abrami, R. Abbiati, B. Posocco +5 more
20150 citations
Semantic Scholar
R04Pharmacokinetic analysis of irinotecan administered in FOLFIRI regimen in combination with bevacizumab from patients enrolled in a genotype-driven phase I study
B. Posocco, A. Buonadonna, E. Marangon, L. Giodini +4 more
20150 citations Open access
Semantic Scholar

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G. Toffoli×33
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G. Toffoli — researcher profile on SciRah
S. Gagno×25
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S. Gagno — researcher profile on SciRah
F. Puglisi×22
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F. Puglisi — researcher profile on SciRah
E. Cecchin×19
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E. Cecchin — researcher profile on SciRah

×18

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E. Marangon — researcher profile on SciRah

Marco Orleni×18

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Marco Orleni — researcher profile on SciRah

Martina Zanchetta×15

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Martina Zanchetta — researcher profile on SciRah

M. Guardascione×15

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M. Guardascione — researcher profile on SciRah

Giovanni Canil×12

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Giovanni Canil — researcher profile on SciRah

A. Buonadonna×11

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A. Buonadonna — researcher profile on SciRah

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R. Roncato — researcher profile on SciRah

A. S. Poetto×9

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A. S. Poetto — researcher profile on SciRah