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I. Lomakin · SciRah

Researcher profile · Semantic Scholar

I. Lomakin

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I. Lomakin — researcher profile on SciRah

h-index: 25
Works: 75
Citations: 4,263

Most-cited papers

Molecular mechanisms of translation initiation in eukaryotes
T. Pestova, V. Kolupaeva, I. Lomakin, E. Pilipenko +3 more
2001Proceedings of the National Academy of Sciences of the United States of America779 citations Open access
Semantic Scholar
The joining of ribosomal subunits in eukaryotes requires eIF5B
T. Pestova, I. Lomakin, Joon-Hwa Lee, Sang K. Choi +2 more
2000Nature428 citations
Semantic Scholar
Dendritic BC1 RNA: Functional Role in Regulation of Translation Initiation
Huidong Wang, Anna Iacoangeli, S. Popp, I. Muslimov +4 more
2002Journal of Neuroscience231 citations Open access
Semantic Scholar
A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.
J. Marcotrigiano, I. Lomakin, N. Sonenberg, T. Pestova +2 more
2001Molecules and Cells228 citations Open access
Semantic Scholar
The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together.
I. Lomakin, Yong Xiong, T. Steitz
2007Cell227 citations Open access
Semantic Scholar
Physical Association of Eukaryotic Initiation Factor 4G (eIF4G) with eIF4A Strongly Enhances Binding of eIF4G to the Internal Ribosomal Entry Site of Encephalomyocarditis Virus and Is Required for Internal Initiation of Translation
I. Lomakin, C. Hellen, T. Pestova
2000Molecular and Cellular Biology217 citations Open access
Semantic Scholar
Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase
O. Laptenko, JooKyung Lee, I. Lomakin, S. Borukhov
2003EMBO Journal202 citations Open access
Semantic Scholar
The Mechanism of Inhibition of Protein Synthesis by the Proline-Rich Peptide Oncocin
R. Roy, I. Lomakin, M. Gagnon, T. Steitz
2015Nature Structural &Molecular Biology178 citations Open access
Semantic Scholar
Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA
Shuai Yuan, Lei Peng, Jonathan J. Park, Ying-Xia Hu +7 more
2020bioRxiv176 citations Open access
Semantic Scholar
Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition
M. Gagnon, R. Roy, I. Lomakin, T. Florin +2 more
2016Nucleic Acids Research170 citations Open access
Semantic Scholar
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing.
I. Lomakin, V. Kolupaeva, A. Marintchev, G. Wagner +1 more
2003Genes & Development157 citations Open access
Semantic Scholar
Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association.
V. Kolupaeva, A. Unbehaun, I. Lomakin, C. Hellen +1 more
2005RNA: A publication of the RNA Society142 citations Open access
Semantic Scholar
The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH
I. Lomakin, Nikolay E. Shirokikh, M. Yusupov, C. Hellen +1 more
2006EMBO Journal126 citations Open access
Semantic Scholar
Position of the CrPV IRES on the 40S subunit and factor dependence of IRES/80S ribosome assembly
T. Pestova, I. Lomakin, C. Hellen
2004EMBO Reports117 citations Open access
Semantic Scholar
Eukaryotic Initiation Factors 4G and 4A Mediate Conformational Changes Downstream of the Initiation Codon of the Encephalomyocarditis Virus Internal Ribosomal Entry Site
V. Kolupaeva, I. Lomakin, T. Pestova, C. Hellen
2003Molecular and Cellular Biology113 citations Open access
Semantic Scholar
The initiation of mammalian protein synthesis and the mechanism of scanning
I. Lomakin, T. Steitz
2013Nature111 citations Open access
Semantic Scholar
Recent insight into intermediate filament structure
S. Eldirany, I. Lomakin, Minh Ho, C. Bunick
2020Current Opinion in Cell Biology85 citations Open access
Semantic Scholar
EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas.
D. Etemadmoghadam, Walid J Azar, Ying Lei, T. Moujaber +24 more
2017Cancer Research81 citations
Semantic Scholar
Coronavirus Nsp1: Immune Response Suppression and Protein Expression Inhibition
Shuai Yuan, S. Balaji, I. Lomakin, Yong Xiong
2021Frontiers in Microbiology62 citations Open access
Semantic Scholar
Crystal structure of the human ribosome in complex with DENR-MCT-1
I. Lomakin, E. Stolboushkina, A. Vaidya, Chen-Guang Zhao +3 more
2017Cell Reports53 citations Open access
Semantic Scholar
Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing
A. Unbehaun, A. Marintchev, I. Lomakin, T. Didenko +3 more
2007EMBO Journal53 citations Open access
Semantic Scholar
Human keratin 1/10‐1B tetramer structures reveal a knob‐pocket mechanism in intermediate filament assembly
S. Eldirany, Minh Ho, Alexander J Hinbest, I. Lomakin +1 more
2019EMBO Journal47 citations Open access
Semantic Scholar
Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome
Z. Batool, I. Lomakin, Y. Polikanov, C. Bunick
2020Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease
M. K. Armillei, I. Lomakin, J. D. Del Rosso, A. Grada +1 more
2024Antibiotics37 citations Open access
Semantic Scholar
Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism
I. Lomakin, S. Devarkar, Shivali Patel, A. Grada +1 more
2023Nucleic Acids Research28 citations Open access
Semantic Scholar
Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation
I. Lomakin, S. Dmitriev, T. Steitz
2018Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Visualizing the translation landscape in human cells at high resolution
Wei Zheng, Yuekang Zhang, Jimin Wang, Shuhui Wang +11 more
2025Nature Communications18 citations Open access
Semantic Scholar
Crystal Structure of the C-terminal Domain of Human eIF2D and its Implications on Eukaryotic Translation Initiation
A. Vaidya, I. Lomakin, Newlyn N. Joseph, S. Dmitriev +1 more
2017Journal of Molecular Biology16 citations Open access
Semantic Scholar
Visualizing the translation landscape in human cells at high resolution
Wei Zheng, Yuekang Zhang, Jimin Wang, Shuhui Wang +10 more
2024bioRxiv15 citations
Semantic Scholar
Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses
S. Devarkar, Michael B. Vetick, Shravani Balaji, I. Lomakin +5 more
2023Cell Reports14 citations Open access
Semantic Scholar
Clindamycin: A Comprehensive Status Report with Emphasis on Use in Dermatology.
J. D. Del Rosso, M. K. Armillei, I. Lomakin, A. Grada +1 more
2024˜The œJournal of clinical and aesthetic dermatology12 citations
Semantic Scholar
Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1.
Ji-Min Wang, A. Sachpatzidis, Thomas D. Christian, I. Lomakin +2 more
2022Biochemistry11 citations
Semantic Scholar
Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin.
I. Lomakin, S. Devarkar, A. Grada, C. Bunick
2024Journal of Investigative Dermatology8 citations Open access
Semantic Scholar
Crystal structure of the heterocomplex between coil 2B domains of wild-type keratin 1 (KRT1) and keratin 10 (KRT10) containing mutation Cys401Ala
I. Lomakin, C. Bunick
20198 citations
Semantic Scholar
Antimicrobial peptides targeting bacterial ribosome
I. Lomakin, M. Gagnon, T. Steitz
2015OncoTarget8 citations Open access
Semantic Scholar
A triple-action inhibitory mechanism of allosteric TYK2-specific inhibitors.
Ji-Min Wang, I. Lomakin, Victor S. Batista, C. Bunick
2025Journal of Investigative Dermatology5 citations Open access
Semantic Scholar
Crystal Structure of Keratin 1/10(C401A) 2B Heterodimer Demonstrates a Proclivity for the C-Terminus of Helix 2B to Form Higher Order Molecular Contacts
I. Lomakin, Alexander J Hinbest, Minh Ho, S. Eldirany +1 more
2020The Yale Journal of Biology and Medicine5 citations
Semantic Scholar
Structural properties of target binding by profilaggrin A and B domains and other S100 fused-type calcium-binding proteins
Alexander J Hinbest, S. Kim, S. Eldirany, I. Lomakin +3 more
2020Journal of dermatological science (Amsterdam)5 citations Open access
Semantic Scholar
Unveiling the secrets of vimentin filament architecture relevant to human disease
I. Lomakin, Minh Ho, C. Bunick
2024Nature Structural & Molecular Biology4 citations
Semantic Scholar
713 The crystal structure of keratin 1/10(Cys401Ala) helix 2B heterodimer determined at 2.0 Å resolution
I. Lomakin, Alexander J Hinbest, C. Bunick
20184 citations Open access
Semantic Scholar
Peptidyl transferase inhibitors arrest the ribosome at specific amino acid codons: insights from an integrated approach
K. A. Akulich, Pavel G. Sinitcyn, I. Lomakin, D. Andreev +5 more
20174 citations
Semantic Scholar
576 Crystal structure of sarecycline bound to the 70S bacterial ribosome reveals structural differences from other tetracyclines at atomic resolution
Z. Batool, I. Lomakin, Y. Polikanov, C. Bunick
2020Journal of Investigative Dermatology3 citations Open access
Semantic Scholar
[Cloning of the cDNA coding for human prointerleukin-1 alpha and prointerleukin-1 beta].
S. Kotenko, M. T. Bulenkov, V. Veiko, S. M. Epishin +1 more
1989Doklady Akademii nauk SSSR3 citations
Semantic Scholar
Dual site targeting of the bacterial 70S ribosome by tetracyclines
S. Devarkar, I. Lomakin, Jimin Wang, A. Grada +1 more
2026Nature Communications2 citations Open access
Semantic Scholar
Autosomal dominant SLURP1 variants cause palmoplantar keratoderma and progressive symmetric erythrokeratoderma
Xingyuan Jiang, R. Mortlock, I. Lomakin, Jing Zhou +4 more
2025British Journal of Dermatology2 citations Open access
Semantic Scholar
Structures redefine the mechanism of action for tetracyclines
S. Devarkar, I. Lomakin, Ji-Min Wang, A. Grada +1 more
2025bioRxiv1 citations Open access
Semantic Scholar
Practical Guide for Implementing Cryo-Electron Microscopy Structure Determination in Dermatology Research
I. Lomakin, S. Devarkar, Christian Freniere, C. Bunick
2024Journal of Investigative Dermatology1 citations Open access
Semantic Scholar
Crystal structure of the C-terminal domain of DENR
I. Lomakin, S. De, Ji-Min Wang, Aditi N. Borkar +1 more
2020Computational and Structural Biotechnology Journal1 citations Open access
Semantic Scholar
689 The x-ray crystal structure of human keratin 1 with S233L mutation demonstrates mechanism of pathogenic tonotubular keratin formation leading to epidermolytic palmoplantar keratoderma
S. Eldirany, Alexander J Hinbest, I. Lomakin, C. Bunick
20181 citations Open access
Semantic Scholar
[Biosynthesis of human recombinant interleukin-8 in Escherichia coli].
I. Lomakin, S. V. Mashko, S. M. Epishin, S. A. Ketlinskiĭ +3 more
1993Doklady Akademii Nauk1 citations
Semantic Scholar

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