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S. Prudente · SciRah

Researcher profile · Semantic Scholar

S. Prudente

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S. Prudente — researcher profile on SciRah

h-index: 30
Works: 107
Citations: 2,920

Most-cited papers

Role of insulin resistance in kidney dysfunction: insights into the mechanism and epidemiological evidence.
S. D. De Cosmo, C. Menzaghi, S. Prudente, V. Trischitta
2013Nephrology, Dialysis and Transplantation202 citations
Semantic Scholar
Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus.
S. Prudente, Prapaporn Jungtrakoon, A. Marucci, O. Ludovico +20 more
2015American Journal of Human Genetics134 citations Open access
Semantic Scholar
Association Between a Genetic Variant Related to Glutamic Acid Metabolism and Coronary Heart Disease in Type 2 Diabetes
L. Qi, Q. Qi, S. Prudente, Christine Mendonça +18 more
2013Journal of the American Medical Association (JAMA)133 citations Open access
Semantic Scholar
The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction.
S. Bacci, O. Ludovico, S. Prudente, Yuan-yuan Zhang +13 more
2005Diabetes119 citations
Semantic Scholar
A Functional Variant of the Adipocyte Glycerol Channel Aquaporin 7 Gene Is Associated With Obesity and Related Metabolic Abnormalities
S. Prudente, E. Flex, E. Morini, F. Turchi +10 more
2007Diabetes117 citations
Semantic Scholar
The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy.
S. Prudente, M. Hribal, E. Flex, F. Turchi +9 more
2005Diabetes117 citations Open access
Semantic Scholar
Mutations Impairing GSK3-Mediated MAF Phosphorylation Cause Cataract, Deafness, Intellectual Disability, Seizures, and a Down Syndrome-like Facies
M. Niceta, E. Stellacci, K. Gripp, G. Zampino +27 more
2015American Journal of Human Genetics113 citations Open access
Semantic Scholar
The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases.
S. Prudente, G. Sesti, A. Pandolfi, F. Andreozzi +2 more
2012Endocrine reviews113 citations Open access
Semantic Scholar
The ENPP1 K121Q Polymorphism Is Associated With Type 2 Diabetes in European Populations
J. McAteer, S. Prudente, S. Bacci, H. Lyon +3 more
2008Diabetes104 citations
Semantic Scholar
The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy.
A. Bulotta, O. Ludovico, A. Coco, R. Di Paola +5 more
2005Journal of Clinical Endocrinology and Metabolism89 citations
Semantic Scholar
Serum Resistin, Cardiovascular Disease and All-Cause Mortality in Patients with Type 2 Diabetes
C. Menzaghi, S. Bacci, L. Salvemini, Christine Mendonça +16 more
2013PLoS ONE86 citations Open access
Semantic Scholar
Insulin signaling regulating genes: effect on T2DM and cardiovascular risk
S. Prudente, E. Morini, V. Trischitta
2009Nature Reviews Endocrinology86 citations
Semantic Scholar
The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.
S. Prudente, D. Scarpelli, M. Chandalia, Yuan-yuan Zhang +12 more
2009Journal of Clinical Endocrinology and Metabolism66 citations Open access
Semantic Scholar
TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells
F. Andreozzi, G. Formoso, S. Prudente, M. Hribal +6 more
2008Arteriosclerosis, Thrombosis and Vascular Biology57 citations Open access
Semantic Scholar
ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes
Domenico Delia, S. Mizutani, S. Panigone, E. Tagliabue +9 more
2000British Journal of Cancer57 citations Open access
Semantic Scholar
Interaction Between PPARγ2 Variants and Gender on the Modulation of Body Weight
E. Morini, V. Tassi, Daria Capponi, O. Ludovico +3 more
2008Obesity54 citations Open access
Semantic Scholar
ROCK2 and Its Alternatively Spliced Isoform ROCK2m Positively Control the Maturation of the Myogenic Program
M. Pelosi, F. Marampon, B. Zani, S. Prudente +8 more
2007Molecular and Cellular Biology53 citations Open access
Semantic Scholar
ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies
R. Di Paola, Nunzia Caporarello, A. Marucci, C. Dimatteo +11 more
2011PLoS ONE49 citations Open access
Semantic Scholar
ENPP1 gene, insulin resistance and related clinical outcomes
S. Bacci, S. D. De Cosmo, S. Prudente, V. Trischitta
2007Current opinion in clinical nutrition and metabolic care39 citations
Semantic Scholar
GALNT2 Expression Is Reduced in Patients with Type 2 Diabetes: Possible Role of Hyperglycemia
A. Marucci, L. di Mauro, C. Menzaghi, S. Prudente +5 more
2013PLoS ONE38 citations Open access
Semantic Scholar
Role of the ENPP1 K121Q Polymorphism in Glucose Homeostasis
R. Baratta, Paola Rossetti, S. Prudente, F. Barbetti +6 more
2008Diabetes37 citations Open access
Semantic Scholar
The Q121/Q121 Genotype of ENPP1/PC‐1 Is Associated with Lower BMI in Non‐diabetic Whites
S. Prudente, M. Chandalia, E. Morini, R. Baratta +4 more
2007Obesity36 citations
Semantic Scholar
PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid
M. Morieri, Hetal S. Shah, J. Sjaarda, P. Lenzini +23 more
2020Diabetes34 citations Open access
Semantic Scholar
The TRIB3 R84 variant is associated with increased carotid intima-media thickness in vivo and with enhanced MAPK signalling in human endothelial cells.
G. Formoso, P. Di Tomo, F. Andreozzi, E. Succurro +7 more
2011Cardiovascular Research33 citations Open access
Semantic Scholar
Impact of the PPAR-γ2 Pro12Ala Polymorphism and ACE Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: Evidence From BENEDICT
S. D. De Cosmo, N. Motterlini, S. Prudente, F. Pellegrini +5 more
2009Diabetes32 citations Open access
Semantic Scholar
Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes
S. Prudente, Hetal S. Shah, D. Bailetti, M. Pezzolesi +7 more
2015Diabetes31 citations Open access
Semantic Scholar
The IRS-1 G972R polymorphism and Type 2 Diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of “low frequency-low risk” variants
E. Morini, S. Prudente, E. Succurro, M. Chandalia +11 more
2009Diabetologia31 citations Open access
Semantic Scholar
The Type 2 Diabetes and Insulin-Resistance Locus Near IRS1 Is A Determinant of HDL Cholesterol and Triglycerides Levels Among Diabetic Subjects
Rajani Sharma, S. Prudente, F. Andreozzi, C. Powers +11 more
2011Atherosclerosis30 citations Open access
Semantic Scholar
Two new severe mutations causing guanidinoacetate methyltransferase deficiency.
C. Carducci, V. Leuzzi, C. Carducci, S. Prudente +2 more
2000Molecular Genetics and Metabolism30 citations
Semantic Scholar
PPARγ2 P12A polymorphism and albuminuria in patients with type 2 diabetes: a meta-analysis of case-control studies.
S. D. De Cosmo, S. Prudente, O. Lamacchia, Emanuela Lapice +8 more
2011Nephrology, Dialysis and Transplantation29 citations
Semantic Scholar
The ENPP1 Q121 Variant Predicts Major Cardiovascular Events in High-Risk Individuals
S. Bacci, S. Rizza, S. Prudente, B. Spoto +22 more
2011Diabetes29 citations Open access
Semantic Scholar
The K 121 Q Polymorphism of the ENPP 1 / PC1 Gene Is Associated With Insulin Resistance / Atherogenic Phenotypes , Including Earlier Onset of Type 2 Diabetes and Myocardial Infarction
S. Bacci, O. Ludovico, S. Prudente, Yuan-yuan Zhang +13 more
200529 citations
Semantic Scholar
Joint effect of insulin signalling genes on cardiovascular events and on whole body and endothelial insulin resistance
S. Bacci, S. Prudente, M. Copetti, B. Spoto +21 more
2012Atherosclerosis28 citations Open access
Semantic Scholar
Interaction of DIO2 T92A and PPARγ2 P12A Polymorphisms in the Modulation of Metabolic Syndrome
M. Fiorito, I. Torrente, S. D. De Cosmo, V. Guida +11 more
2007Obesity28 citations Open access
Semantic Scholar
Insights From Molecular Characterization of Adult Patients of Families With Multigenerational Diabetes
S. Pezzilli, O. Ludovico, T. Biagini, L. Mercuri +11 more
2017Diabetes26 citations
Semantic Scholar
The Pleiotropic Effect of the ENPP1 (PC-1) Gene on Insulin Resistance, Obesity, and Type 2 Diabetes
S. Prudente, V. Trischitta
200625 citations
Semantic Scholar
Unusual association of SCN2A epileptic encephalopathy with severe cortical dysplasia detected by prenatal MRI.
S. Bernardo, E. Marchionni, S. Prudente, P. De Liso +4 more
2017European journal of paediatric neurology24 citations
Semantic Scholar
Genetic characterization of suspected MODY patients in Tunisia by targeted next-generation sequencing
Hamza Dallali, S. Pezzilli, Meriem Hechmi, O. Sallem +16 more
2019Acta Diabetologica23 citations
Semantic Scholar
The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells
S. Prudente, E. Morini, J. Larmon, F. Andreozzi +16 more
2011Atherosclerosis23 citations Open access
Semantic Scholar
A genetic marker of hyperuricemia predicts cardiovascular events in a meta-analysis of three cohort studies in high risk patients.
A. Testa, S. Prudente, D. Leonardis, B. Spoto +8 more
2015NMCD. Nutrition Metabolism and Cardiovascular Diseases22 citations
Semantic Scholar
A Polymorphism at the IL6ST (gp130) Locus Is Associated With Traits of the Metabolic Syndrome
L. Gottardo, S. D. De Cosmo, Yuan-yuan Zhang, C. Powers +5 more
2008Obesity22 citations Open access
Semantic Scholar
Genetic prediction of common diseases. Still no help for the clinical diabetologist!
S. Prudente, B. Dallapiccola, F. Pellegrini, A. Doria +1 more
2012NMCD. Nutrition Metabolism and Cardiovascular Diseases21 citations Open access
Semantic Scholar
Association of the 1q25 Diabetes-Specific Coronary Heart Disease Locus With Alterations of the γ-Glutamyl Cycle and Increased Methylglyoxal Levels in Endothelial Cells
Ada Admin, Caterina Pipino, Hetal S. Shah, S. Prudente +7 more
2020Diabetes20 citations Open access
Semantic Scholar
Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation
Sara Haydar, F. Grigorescu, M. Vintilă, Yannick Cogne +36 more
2019PLoS ONE20 citations Open access
Semantic Scholar
IRS1 G972R Missense Polymorphism Is Associated With Failure to Oral Antidiabetes Drugs in White Patients With Type 2 Diabetes From Italy
S. Prudente, E. Morini, D. Lucchesi, O. Lamacchia +11 more
2014Diabetes20 citations Open access
Semantic Scholar
TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion
S. Prudente, R. Baratta, F. Andreozzi, E. Morini +12 more
2010Diabetologia20 citations Open access
Semantic Scholar
Association of osteocalcin, osteoprotegerin, and osteopontin with cardiovascular disease and retinopathy in type 2 diabetes
E. Maddaloni, L. Coraggio, Rocco Amendolara, M. G. Baroni +16 more
2023Diabetes/Metabolism Research Reviews19 citations Open access
Semantic Scholar
Identification and Clinical Characterization of Adult Patients with Multigenerational Diabetes Mellitus
O. Ludovico, M. Carella, L. Bisceglia, G. Basile +6 more
2015PLoS ONE18 citations Open access
Semantic Scholar
The allelic variant of LAR gene promoter –127 bp T→A is associated with reduced risk of obesity and other features related to insulin resistance
G. Miscio, V. Tassi, A. Coco, T. Soccio +10 more
2004Journal of molecular medicine18 citations
Semantic Scholar
Gain of function of Malate Dehydrogenase 2 (MDH2) and familial hyperglycemia.
Prapaporn Jungtrakoon Thamtarana, A. Marucci, Luca Pannone, A. Bonnefond +22 more
2021Journal of Clinical Endocrinology and Metabolism17 citations Open access
Semantic Scholar

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