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Binfeng Xia · SciRah

Researcher profile · Semantic Scholar

Binfeng Xia

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Binfeng Xia — researcher profile on SciRah

h-index: 13
Works: 25
Citations: 619

Most-cited papers

Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective
Tycho Heimbach, Yuan Chen, Jun Chen, Vaishali Dixit +15 more
2020Clinical pharmacology and therapy114 citations Open access
Semantic Scholar
Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies.
C. Tistaert, Tycho Heimbach, Binfeng Xia, N. Parrott +2 more
2019Journal of Pharmacy and Science69 citations Open access
Semantic Scholar
A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy
Binfeng Xia, Tycho Heimbach, Rakesh Gollen, Charvi Nanavati +1 more
2013AAPS Journal63 citations Open access
Semantic Scholar
Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data
Tycho Heimbach, Binfeng Xia, Tsu-Han Lin, Handan He
2012AAPS Journal53 citations Open access
Semantic Scholar
Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability
Binfeng Xia, Tycho Heimbach, Handan He, Tsu-Han Lin
2012Biopharmaceutics & drug disposition47 citations
Semantic Scholar
Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate
F. Kesisoglou, Binfeng Xia, N. Agrawal
2015AAPS Journal45 citations Open access
Semantic Scholar
Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect
He-Fei Zhang, Binfeng Xia, J. Sheng, Tycho Heimbach +5 more
2014AAPS PharmSciTech34 citations Open access
Semantic Scholar
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Amais Ahmad, X. Pepin, L. Aarons, Yuya Wang +65 more
2020European journal of pharmaceutics and biopharmaceutics32 citations Open access
Semantic Scholar
Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem
Binfeng Xia, Zhen Yang, Haiying Zhou, V. Lukacova +3 more
2015AAPS Journal29 citations Open access
Semantic Scholar
Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs.
Sanjaykumar Patel, Wei Zhu, Binfeng Xia, Navneet K. Sharma +4 more
2019Journal of Pharmacy and Science27 citations
Semantic Scholar
Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound
Binfeng Xia, Tycho Heimbach, Tsu-Han Lin, Shou-Feng Li +3 more
2013AAPS PharmSciTech26 citations Open access
Semantic Scholar
Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions
Binfeng Xia, Tycho Heimbach, Tsu-Han Lin, Handan He +2 more
2012Cancer Chemotherapy and Pharmacology23 citations
Semantic Scholar
Effect of TPGS surfactant on dissolution sensitivity of a poorly water-soluble drug using high-shear wet granulation
S. Sotthivirat, R. Ramesh, W. Wasylaschuk, Cory Bottone +5 more
202013 citations
Semantic Scholar
Pharmacokinetics of Subcutaneous Dupilumab Injection With an Autoinjector Device or Prefilled Syringe
Yehuda Z. Cohen, Xiaojiao Zhang, Binfeng Xia, M. Kosloski +4 more
2022Clinical pharmacology in drug development12 citations Open access
Semantic Scholar
Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir.
Binfeng Xia, A. Barve, Tycho Heimbach, Tao Zhang +9 more
2014European Journal of Pharmaceutical Sciences12 citations
Semantic Scholar
Atypical Kinetics of Valproic Acid Glucuronidation In vitro and In vivo inHumans
H. Wong, Binfeng Xia, V. Tong, Sanjeev Kumar +1 more
20126 citations Open access
Semantic Scholar
A canine biorelevant dissolution method for predicting in vivo performance of orally administered sustained release matrix tablets
Paul L. Walsh, J. Bothe, S. Bhardwaj, Mengwei Hu +5 more
2016Drug Development and Industrial Pharmacy5 citations
Semantic Scholar
Preclinical pharmacokinetics and metabolism of MNP001, a piperidine analog of 3‐carbamyl compounds
Binfeng Xia, De-Suo Wang, L. M. Fox
2011Biopharmaceutics & drug disposition3 citations
Semantic Scholar
Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem
Binfeng Xia, Zhen Yang, Haiying Zhou, V. Lukacova +3 more
2015AAPS Journal2 citations Open access
Semantic Scholar
Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data
Tycho Heimbach, Binfeng Xia, Tsu-Han Lin, Handan He
2012AAPS Journal2 citations Open access
Semantic Scholar
Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate
F. Kesisoglou, Binfeng Xia, N. Agrawal
2015AAPS Journal1 citations Open access
Semantic Scholar
HPLC/MS/MS analysis of 3-carbamyl-4-methylpyrrole analog MNP001, a highly potent antihypertensive agent, in rat plasma.
Binfeng Xia, Ting Wang, L. M. Fox, De-Suo Wang
2009Journal of chromatography. B, Analytical technologies in the biomedical and life sciences1 citations
Semantic Scholar
An open-label phase 1 study of DCC-2812 monotherapy in patients with advanced genitourinary cancers.
I. Rodriguez Rivera, Bicky Thapa, C. Psoinos, J. Jennings +7 more
2026Journal of Clinical Oncology0 citations
Semantic Scholar
A Physiologically Based Pharmacokinetic (PBPK) Model for Adults to Characterize BIVV001 Activity, a New Class of Factor VIII (FVIII) with High Sustained Factor Activity
Binfeng Xia, S. Katragadda, Donato Teutonico, S. Macha +2 more
2020Blood0 citations Open access
Semantic Scholar
Preclinical pharmacokinetics of the 3-carbamyl-4-methylpyrrole analog, MNP001, a novel antihypertensive agent
Binfeng Xia
20090 citations
Semantic Scholar

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Tycho Heimbach×11
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F. Kesisoglou×6
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