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D. Musson · SciRah

Researcher profile · Semantic Scholar

D. Musson

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D. Musson — researcher profile on SciRah

h-index: 27
Works: 84
Citations: 2,462

Most-cited papers

Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double‐blind, placebo‐controlled studies with single oral doses
G. Herman, C. Stevens, K. van Dyck, A. Bergman +14 more
2005Clinical pharmacology and therapy543 citations
Semantic Scholar
Pharmacokinetics and bioavailability of Sinemet CR: a summary of human studies.
Kuang C. Yeh, T. August, D. Bush, K. Lasseter +4 more
1989Neurology182 citations
Semantic Scholar
Phase 1 Trial of Subcutaneous rAvPAL-PEG in Subjects with Phenylketonuria
N. Longo, C. Harding, B. Burton, D. Grange +8 more
2014The Lancet144 citations Open access
Semantic Scholar
Determination of sitagliptin in human urine and hemodialysate using turbulent flow online extraction and tandem mass spectrometry.
W. Zeng, D. Musson, A. Fisher, Li Chen +3 more
2008Journal of Pharmaceutical and Biomedical Analysis96 citations
Semantic Scholar
In Vitro and in Vivo Properties of 3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA Receptor α5 Subtype-Selective Inverse Agonist
J. Atack, K. Maubach, K. Wafford, D. O'Connor +20 more
2009Journal of Pharmacology and Experimental Therapeutics67 citations
Semantic Scholar
Determination of imipenem (N-formimidoyl thienamycin) in human plasma and urine by high-performance liquid chromatography, comparison with microbiological methodology and stability.
D. Gravallese, D. Musson, L. T. Pauliukonis, W. Bayne
1984Journal of Chromatography A64 citations
Semantic Scholar
Immunogenicity of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients With Morquio A Syndrome: Results From MOR-004, a Phase III Trial.
Becky Schweighardt, T. Tompkins, Kelly Lau, Lynne A. Jesaitis +7 more
2015Clinical Therapeutics61 citations
Semantic Scholar
Occurrence of beta-hydroxylated asparagine residues in non-vitamin K-dependent proteins containing epidermal growth factor-like domains.
Craig T. Przysiecki, J. Staggers, H. Ramjit, D. Musson +3 more
1987Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Application of a novel ultra-low elution volume 96-well solid-phase extraction method to the LC/MS/MS determination of simvastatin and simvastatin acid in human plasma.
A. Yang, Li Sun, D. Musson, Jamie J. Zhao
2005Journal of Pharmaceutical and Biomedical Analysis59 citations
Semantic Scholar
Nonclinical evaluation of CNS-administered TPP1 enzyme replacement in canine CLN2 neuronal ceroid lipofuscinosis.
Brian R. Vuillemenot, Derek Kennedy, J. Cooper, Andrew M. S. Wong +14 more
2015Molecular Genetics and Metabolism55 citations
Semantic Scholar
High turbulence liquid chromatography online extraction and tandem mass spectrometry for the simultaneous determination of suberoylanilide hydroxamic acid and its two metabolites in human serum.
L. Du, D. Musson, A. Q. Wang
2005Rapid Communications in Mass Spectrometry47 citations
Semantic Scholar
The disposition and metabolism of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in human subjects.
R. A. Halpin, A. Porras, L. Geer, M. Davis +10 more
2002Drug Metabolism And Disposition46 citations
Semantic Scholar
Pharmacokinetics of Total and Unbound Ertapenem in Healthy Elderly Subjects
D. Musson, A. Majumdar, S. Holland, K. Birk +6 more
2004Antimicrobial Agents and Chemotherapy45 citations Open access
Semantic Scholar
Stability studies of vorinostat and its two metabolites in human plasma, serum and urine.
L. Du, D. Musson, A. Q. Wang
2006Journal of Pharmaceutical and Biomedical Analysis42 citations
Semantic Scholar
A semi-automated 96-well protein precipitation method for the determination of montelukast in human plasma using high performance liquid chromatography/fluorescence detection.
C. Kitchen, A. Q. Wang, D. Musson, A. Yang +1 more
2003Journal of Pharmaceutical and Biomedical Analysis42 citations
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Evaluation of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients with Morquio A Syndrome
Yu-Lan Qi, D. Musson, Becky Schweighardt, T. Tompkins +4 more
2014Clinical Pharmacokinetics41 citations Open access
Semantic Scholar
Investigation of high-throughput ultrafiltration for the determination of an unbound compound in human plasma using liquid chromatography and tandem mass spectrometry with electrospray ionization.
Jin Zhang, D. Musson
2006Journal of chromatography. B, Analytical technologies in the biomedical and life sciences41 citations
Semantic Scholar
A new approach for evaluating carryover and its influence on quantitation in high-performance liquid chromatography and tandem mass spectrometry assay.
W. Zeng, D. Musson, A. Fisher, A. Q. Wang
2006Rapid Communications in Mass Spectrometry40 citations
Semantic Scholar
Concerns in the development of an assay for determination of a highly conjugated adsorption-prone compound in human urine.
Yang Xu, L. Du, M. Rose, I. Fu +2 more
2005Journal of chromatography. B, Analytical technologies in the biomedical and life sciences39 citations
Semantic Scholar
Assay methodology for the quantitation of unbound ertapenem, a new carbapenem antibiotic, in human plasma.
D. Musson, K. Birk, C. Kitchen, Jin Zhang +4 more
2003Journal of chromatography. B, Analytical technologies in the biomedical and life sciences39 citations
Semantic Scholar
Recombinant human tripeptidyl peptidase-1 infusion to the monkey CNS: safety, pharmacokinetics, and distribution.
Brian R. Vuillemenot, Derek Kennedy, Randall P. Reed, R. Boyd +6 more
2014Toxicology and Applied Pharmacology36 citations
Semantic Scholar
Quantitation of norfloxacin, a new antibacterial agent in human plasma and urine by ion-pair reverse-phase chromatography.
L. T. Pauliukonis, D. Musson, W. Bayne
1984Journal of Pharmacy and Science36 citations
Semantic Scholar
A rapid and sensitive liquid chromatography/negative ion tandem mass spectrometry method for the determination of an indolocarbazole in human plasma using 96-well diatomaceous earth plates for solid-liquid extraction [correction of using internal standard (IS) 96-well diatomaceous earth plates for s
A. Q. Wang, W. Zeng, D. Musson, J. Rogers +1 more
2002Rapid Communications in Mass Spectrometry35 citations
Semantic Scholar
Assay methodology for quantification of the ester and ether glucuronide conjugates of diflunisal in human urine.
D. Musson, J. Lin, K. Lyon, D. Tocco +1 more
1985Journal of Chromatography A34 citations
Semantic Scholar
Pharmacokinetics of Intramuscularly Administered Ertapenem
D. Musson, A. Majumdar, K. Birk, S. Holland +8 more
2003Antimicrobial Agents and Chemotherapy32 citations Open access
Semantic Scholar
Simultaneous high-performance liquid chromatographic analysis of carbidopa, levodopa and 3-O-methyldopa in plasma and carbidopa, levodopa and dopamine in urine using electrochemical detection.
D. Titus, T. August, Kuang C. Yeh, R. Eisenhandler +2 more
1990Journal of Chromatography A30 citations
Semantic Scholar
High-throughput liquid chromatography for drug analysis in biological fluids: investigation of extraction column life.
W. Zeng, A. Fisher, D. Musson, A. Q. Wang
2004Journal of chromatography. B, Analytical technologies in the biomedical and life sciences29 citations
Semantic Scholar
Determination of MK-0431 in human plasma using high turbulence liquid chromatography online extraction and tandem mass spectrometry.
W. Zeng, D. Musson, A. Fisher, A. Q. Wang
2006Rapid Communications in Mass Spectrometry27 citations
Semantic Scholar
Relative bioavailability of sapropterin from intact and dissolved sapropterin dihydrochloride tablets and the effects of food: a randomized, open-label, crossover study in healthy adults.
D. Musson, W. Kramer, E. Foehr, F. Bieberdorf +3 more
2010Clinical Therapeutics21 citations
Semantic Scholar
Sensitive method for the quantitative determination of gemfibrozil in dog plasma by liquid-liquid cartridge extraction and liquid chromatography-tandem mass spectrometry.
B. Roadcap, D. Musson, J. Rogers, Jamie J. Zhao
2003Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20 citations
Semantic Scholar
Bioequivalence of an ezetimibe/simvastatin combination tablet and coadministration of ezetimibe and simvastatin as separate tablets in healthy subjects.
E. Migoya, A. Bergman, D. Hreniuk, N. Matthews +17 more
2006International journal of clinical pharmacology and therapeutics19 citations
Semantic Scholar
Column-switching technique for the sensitive determination of ertapenem in human cerebrospinal fluid using liquid chromatography and ultraviolet absorbance detection.
C. Kitchen, D. Musson, A. Fisher
2004Journal of chromatography. B, Analytical technologies in the biomedical and life sciences19 citations
Semantic Scholar
Strategies on efficient method development of on-line extraction assays for determination of MK-0974 in human plasma and urine using turbulent-flow chromatography and tandem mass spectrometry.
Yang Xu, K. Willson, D. Musson
2008Journal of chromatography. B, Analytical technologies in the biomedical and life sciences18 citations
Semantic Scholar
An in vivo microdialysis coupled with liquid chromatography/tandem mass spectrometry study of cortisol metabolism in monkey adipose tissue.
Li Sun, J. Stenken, J. Brunner, K. Michel +4 more
2008Analytical Biochemistry17 citations
Semantic Scholar
Genetic variation in aryl N-acetyltransferase results in significant differences in the pharmacokinetic and safety profiles of amifampridine (3,4-diaminopyridine) phosphate
P. Haroldsen, M. Garovoy, D. Musson, Huiyu Zhou +3 more
2014Pharmacology Research & Perspectives16 citations Open access
Semantic Scholar
A direct injection high-throughput liquid chromatography tandem mass spectrometry method for the determination of a new orally active alphavbeta3 antagonist in human urine and dialysate.
W. Zeng, A. Q. Wang, A. Fisher, D. Musson
2003Rapid Communications in Mass Spectrometry16 citations
Semantic Scholar
Conversion of arylhydroxylamines to electrochemically-active derivatives suitable for high-performance liquid chromatographic analysis with amperometric detection
D. Musson, L. Sternson
198016 citations
Semantic Scholar
High-performance liquid chromatographic analysis of emetine after oxidative activation to a fluorescent product.
S. J. Bannister, J. G. Stevens, D. Musson, L. Sternson
1979Journal of Chromatography A16 citations
Semantic Scholar
Determination of M+4 stable isotope labeled cortisone and cortisol in human plasma by microElution solid-phase extraction and liquid chromatography/tandem mass spectrometry.
A. Yang, Li Sun, D. Musson, Jamie J. Zhao
2006Rapid Communications in Mass Spectrometry15 citations
Semantic Scholar
Elimination of diastereomer interference to determine Telcagepant (MK-0974) in human plasma using on-line turbulent-flow technology and off-line solid-phase extraction coupled with liquid chromatography/tandem mass spectrometry.
Yang Xu, K. Willson, M. Anderson, D. Musson +2 more
2009Journal of chromatography. B, Analytical technologies in the biomedical and life sciences14 citations
Semantic Scholar
Modified high-performance liquid chromatographic method for the determination of ertapenem in human urine: enhanced selectivity and automation.
D. Musson, C. Kitchen, J. Hsieh, K. Birk
2002Journal of chromatography. B, Analytical technologies in the biomedical and life sciences13 citations
Semantic Scholar
Simultaneous quantification of cycloserine and its prodrug acetylacetonylcycloserine in plasma and urine by high-performance liquid chromatography using ultraviolet absorbance and fluorescence after post-column derivatization.
D. Musson, S. M. Maglietto, S. Hwang, D. Gravellese +1 more
1987Journal of Chromatography A13 citations
Semantic Scholar
High-throughput sample preparation procedures for the quantitation of a new bone integrin ανβ3 antagonist in human plasma and urine using liquid chromatography–tandem mass spectrometry
Jin Zhang, W. Zeng, C. Kitchen, A. Q. Wang +1 more
200412 citations
Semantic Scholar
Determination of a beta(3)-agonist in human plasma by LC/MS/MS with semi-automated 48-well diatomaceous earth plate.
A. Q. Wang, A. Fisher, J. Hsieh, A. Cairns +2 more
2001Journal of Pharmaceutical and Biomedical Analysis12 citations
Semantic Scholar
High-performance liquid chromatographic determination of cilastatin in biological fluids.
J. Demetriades, P. R. Souder, L. Entwistle, W. Vincek +2 more
1986Journal of Chromatography A12 citations
Semantic Scholar
Synthetic and preliminary hemodynamic and whole animal toxicity studies on (R,S)-, (R)-, and (S)-2-methyl-3-(2,4,5-trihydroxyphenyl)alanine.
D. Musson, D. Karashima, H. Rubiero, K. Melmon +2 more
1980Journal of Medicinal Chemistry12 citations
Semantic Scholar
Dose selection for intracerebroventricular cerliponase alfa in children with CLN2 disease, translation from animal to human in a rare genetic disease
K. Hammon, G. D. de Hart, Brian R. Vuillemenot, Derek Kennedy +4 more
2021Clinical and Translational Science11 citations Open access
Semantic Scholar
Maternal phenylketonuria syndrome: studies in mice suggest a potential approach to a continuing problem
W. L. Zeile, H. McCune, D. Musson, Brian O’Donnell +4 more
2018Pediatric Research11 citations Open access
Semantic Scholar
Reversed-phase chiral liquid chromatography on polysaccharide-based stationary phase coupled with tandem mass spectrometry for simultaneous determination of four stereoisomers of MK-0974 in human plasma.
Yang Xu, D. Musson
2008Journal of chromatography. B, Analytical technologies in the biomedical and life sciences11 citations
Semantic Scholar
Acetylator Status Impacts Amifampridine Phosphate (Firdapse™) Pharmacokinetics and Exposure to a Greater Extent Than Renal Function.
P. Haroldsen, Z. Sisic, J. Datt, D. Musson +1 more
2017Clinical Therapeutics10 citations Open access
Semantic Scholar

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