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G. Fedele · SciRah

Researcher profile · Semantic Scholar

G. Fedele

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G. Fedele — researcher profile on SciRah

h-index: 33
Works: 102
Citations: 3,246

Most-cited papers

The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia
D. Brusa, Sara Serra, M. Coscia, D. Rossi +8 more
2012Haematologica230 citations Open access
Semantic Scholar
Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines
S. Esposito, P. Stefanelli, N. Fry, G. Fedele +12 more
2019Frontiers in Immunology168 citations Open access
Semantic Scholar
CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells.
L. Frasca, G. Fedele, S. Deaglio, Cristina Capuano +4 more
2006Blood143 citations
Semantic Scholar
CD38 is expressed on human mature monocyte‐derived dendritic cells and is functionally involved in CD83 expression and IL‐12 induction
G. Fedele, L. Frasca, R. Palazzo, E. Ferrero +2 more
2004European Journal of Immunology109 citations Open access
Semantic Scholar
A Drosophila RNAi collection is subject to dominant phenotypic effects
Edward W. Green, G. Fedele, F. Giorgini, C. Kyriacou
2014Nature Methods108 citations
Semantic Scholar
Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells.
C. Ausiello, M. Cerquetti, G. Fedele, F. Spensieri +4 more
2006Microbes and infection107 citations Open access
Semantic Scholar
An electromagnetic field disrupts negative geotaxis in Drosophila via a CRY-dependent pathway
G. Fedele, Edward W. Green, E. Rosato, C. Kyriacou
2014Nature Communications105 citations Open access
Semantic Scholar
CD38 and CD157 as Receptors of the Immune System: A Bridge Between Innate and Adaptive Immunity
F. Malavasi, S. Deaglio, E. Ferrero, A. Funaro +12 more
2006Molecular Medicine101 citations Open access
Semantic Scholar
Lipopolysaccharides from Bordetella pertussis and Bordetella parapertussis Differently Modulate Human Dendritic Cell Functions Resulting in Divergent Prevalence of Th17-Polarized Responses1
G. Fedele, Maria Nasso, F. Spensieri, R. Palazzo +3 more
2008Journal of Immunology95 citations Open access
Semantic Scholar
Genetic Analysis of Circadian Responses to Low Frequency Electromagnetic Fields in Drosophila melanogaster
G. Fedele, Mathew D. Edwards, Supriya Bhutani, John M. Hares +6 more
2014PLoS Genetics93 citations Open access
Semantic Scholar
Bordetella pertussis Commits Human Dendritic Cells to Promote a Th1/Th17 Response through the Activity of Adenylate Cyclase Toxin and MAPK-Pathways
G. Fedele, F. Spensieri, R. Palazzo, Maria Nasso +3 more
2010PLoS ONE84 citations Open access
Semantic Scholar
Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses.
C. Ausiello, G. Fedele, F. Urbani, R. Lande +2 more
2002Journal of Infectious Diseases84 citations Open access
Semantic Scholar
Bordetella pertussis-Infected Human Monocyte-Derived Dendritic Cells Undergo Maturation and Induce Th1 Polarization and Interleukin-23 Expression
G. Fedele, P. Stefanelli, F. Spensieri, C. Fazio +2 more
2005Infection and Immunity81 citations Open access
Semantic Scholar
IFN-γ Arms Human Dendritic Cells to Perform Multiple Effector Functions1
L. Frasca, Maria Nasso, F. Spensieri, G. Fedele +3 more
2008Journal of Immunology79 citations Open access
Semantic Scholar
Bordetella pertussis Inhibition of Interleukin-12 (IL-12) p70 in Human Monocyte-Derived Dendritic Cells Blocks IL-12 p35 through Adenylate Cyclase Toxin-Dependent Cyclic AMP Induction
F. Spensieri, G. Fedele, C. Fazio, Maria Nasso +3 more
2006Infection and Immunity79 citations
Semantic Scholar
Genetically Detoxified Pertussis Toxin Induces Th1/Th17 Immune Response through MAPKs and IL-10-Dependent Mechanisms1
Maria Nasso, G. Fedele, F. Spensieri, R. Palazzo +3 more
2009Journal of Immunology70 citations Open access
Semantic Scholar
Essential elements of radical pair magnetosensitivity in Drosophila
Adam A. Bradlaugh, G. Fedele, Anna L. Munro, C. Hansen +6 more
2021bioRxiv59 citations Open access
Semantic Scholar
Attenuated Bordetella pertussis Vaccine Candidate BPZE1 Promotes Human Dendritic Cell CCL21-Induced Migration and Drives a Th1/Th17 Response
G. Fedele, Manuela Bianco, A. Debrie, C. Locht +1 more
2011Journal of Immunology59 citations Open access
Semantic Scholar
Nitric oxide interacts with monoamine oxidase to modulate aggression and anxiety-like behaviour.
Héctor Carreño Gutiérrez, A. O'Leary, F. Freudenberg, G. Fedele +5 more
2017European Neuropsychopharmacology58 citations Open access
Semantic Scholar
Hepatitis B specific T cell immunity induced by primary vaccination persists independently of the protective serum antibody level.
M. Carollo, R. Palazzo, Manuela Bianco, E. Pandolfi +6 more
2013Vaccine55 citations Open access
Semantic Scholar
Prevalence of SARS-CoV-2 IgG antibodies in an area of northeastern Italy with a high incidence of COVID-19 cases: a population-based study
P. Stefanelli, A. Bella, G. Fedele, S. Pancheri +18 more
2020Clinical Microbiology and Infection52 citations Open access
Semantic Scholar
Immunomodulatory activities of surface-layer proteins obtained from epidemic and hypervirulent Clostridium difficile strains.
Manuela Bianco, G. Fedele, A. Quattrini, P. Spigaglia +3 more
2011Journal of Medical Microbiology50 citations Open access
Semantic Scholar
T-cell immune responses to Bordetella pertussis infection and vaccination.
G. Fedele, Antonio Cassone, C. Ausiello
2015Pathogens and Disease46 citations
Semantic Scholar
60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells.
C. Ausiello, G. Fedele, R. Palazzo, F. Spensieri +2 more
2006Microbes and infection46 citations Open access
Semantic Scholar
The Virulence Factors of Bordetella pertussis: Talented Modulators of Host Immune Response
G. Fedele, Manuela Bianco, C. Ausiello
2013Archivum Immunologiae et Therapiae Experimentalis44 citations
Semantic Scholar
IFN-gamma arms human dendritic cells to perform multiple effector functions.
L. Frasca, Maria Nasso, F. Spensieri, G. Fedele +3 more
2008Journal of Immunology44 citations
Semantic Scholar
Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease
Yi-Zhou Yu, G. Fedele, I. Celardo, S. H. Loh +1 more
2021Cell Death and Disease43 citations Open access
Semantic Scholar
Evidence of increased circulation of Bordetella pertussis in the Italian adult population from seroprevalence data (2012-2013).
R. Palazzo, M. Carollo, G. Fedele, C. Rizzo +4 more
2016Journal of Medical Microbiology42 citations Open access
Semantic Scholar
Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity
G. Fedele, Ilaria Schiavoni, I. Adkins, Nela Klimova +1 more
2017Toxins39 citations Open access
Semantic Scholar
Parents as source of pertussis transmission in hospitalized young infants
G. Fedele, M. Carollo, R. Palazzo, P. Stefanelli +22 more
2017Infection38 citations
Semantic Scholar
Evaluation of humoral and cellular response to four vaccines against COVID-19 in different age groups: A longitudinal study
G. Fedele, F. Trentini, Ilaria Schiavoni, S. Abrignani +27 more
2022Frontiers in Immunology36 citations Open access
Semantic Scholar
A natural pertactin deficient strain of Bordetella pertussis shows improved entry in human monocyte-derived dendritic cells.
P. Stefanelli, C. Fazio, G. Fedele, F. Spensieri +2 more
2009The New Microbiologica35 citations
Semantic Scholar
Lipooligosaccharide from Bordetella pertussis induces mature human monocyte-derived dendritic cells and drives a Th2 biased response.
G. Fedele, I. Celestino, F. Spensieri, L. Frasca +6 more
2007Microbes and infection33 citations Open access
Semantic Scholar
Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells
V. Marcellini, Eva Piano Mortari, G. Fedele, F. Gesualdo +6 more
2017Frontiers in Immunology32 citations Open access
Semantic Scholar
Analysis of the immune response in infants hospitalized with viral bronchiolitis shows different Th1/Th2 profiles associated with respiratory syncytial virus and human rhinovirus
G. Fedele, Ilaria Schiavoni, R. Nenna, A. Pierangeli +5 more
2018Pediatric Allergy and Immunology31 citations
Semantic Scholar
Relative effectiveness of monovalent and bivalent mRNA boosters in preventing severe COVID-19 due to omicron BA.5 infection up to 4 months post-administration in people aged 60 years or older in Italy: a retrospective matched cohort study.
A. Mateo-Urdiales, C. Sacco, E. Fotakis, M. Del Manso +13 more
2023Lancet. Infectious Diseases (Print)30 citations Open access
Semantic Scholar
Geographical analysis of diapause inducibility in European Drosophila melanogaster populations.
M. Pegoraro, Valeria Zonato, Elizabeth R Tyler, G. Fedele +2 more
2017Journal of insect physiology30 citations Open access
Semantic Scholar
Use of Whole-Blood Samples in In-House Bulk and Single-Cell Antigen-Specific Gamma Interferon Assays for Surveillance of Mycobacterium tuberculosis Infections
R. Palazzo, F. Spensieri, M. Massari, G. Fedele +4 more
2007Clinical and Vaccine Immunology29 citations Open access
Semantic Scholar
CD38 modulates respiratory syncytial virus‐driven proinflammatory processes in human monocyte‐derived dendritic cells
Ilaria Schiavoni, C. Scagnolari, A. Horenstein, P. Leone +4 more
2018Immunology28 citations Open access
Semantic Scholar
Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization
P. Stefanelli, G. Buttinelli, P. Vacca, A. Tozzi +5 more
2017Human Vaccines & Immunotherapeutics27 citations Open access
Semantic Scholar
Identity and ranking of colonic mesenchymal stromal cells
M. Signore, Anna Maria Cerio, A. Boe, A. Pagliuca +10 more
2012Journal of Cellular Physiology26 citations
Semantic Scholar
Paracetamol Is Associated with a Lower Risk of COVID-19 Infection and Decreased ACE2 Protein Expression: A Retrospective Analysis
N. S. Leal, Yi-Jung Yu, Yuwen Chen, G. Fedele +1 more
2021COVID24 citations Open access
Semantic Scholar
Suppression of intestinal dysfunction in a Drosophila model of Parkinson’s disease is neuroprotective
G. Fedele, Samantha H. Y. Loh, I. Celardo, N. S. Leal +3 more
2022Nature Aging23 citations Open access
Semantic Scholar
The second exon-encoded factor XII region is involved in the interaction of factor XII with factor XI and does not contribute to the binding site for negatively charged surfaces.
F. Citarella, G. Fedele, D. Roem, A. Fantoni +1 more
1998Blood23 citations
Semantic Scholar
Protection against severe COVID-19 after second booster dose of adapted bivalent (original/Omicron BA.4-5) mRNA vaccine in persons ≥ 60 years, by time since infection, Italy, 12 September to 11 December 2022
M. Fabiani, A. Mateo-Urdiales, C. Sacco, E. Fotakis +13 more
2023Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin22 citations Open access
Semantic Scholar
Diabetes Affects Antibody Response to SARS-CoV-2 Vaccination in Older Residents of Long-Term Care Facilities: Data From the GeroCovid Vax Study.
Enrico Virgilio, C. Trevisan, A. Abbatecola, A. Malara +9 more
2022Diabetes Care21 citations Open access
Semantic Scholar
Does Breastfeeding Protect Young Infants From Pertussis? Case-control Study and Immunologic Evaluation
E. Pandolfi, F. Gesualdo, E. Carloni, A. Villani +5 more
2017The Pediatric Infectious Disease Journal21 citations
Semantic Scholar
60-kDa heat shock protein of Chlamydia pneumoniae is a target of T-cell immune response.
C. Ausiello, R. Palazzo, F. Spensieri, G. Fedele +4 more
2005Journal of Biological Regulators and Homeostatic Agents19 citations
Semantic Scholar
Prevalence of SARS-CoV-2 infection in Italian pediatric population: a regional seroepidemiological study
M. Comar, Simone Benvenuto, M. Lazzerini, G. Fedele +7 more
2021Italian Journal of Pediatrics17 citations Open access
Semantic Scholar
Persistence of T-cell immune response induced by two acellular pertussis vaccines in children five years after primary vaccination.
R. Palazzo, M. Carollo, Manuela Bianco, G. Fedele +6 more
2016The New Microbiologica17 citations
Semantic Scholar

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