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R. Tasneen · SciRah

Researcher profile · Semantic Scholar

R. Tasneen

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R. Tasneen — researcher profile on SciRah

h-index: 24
Works: 48
Citations: 2,286

Most-cited papers

Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions.
J. Harper, Ciaran Skerry, S. Davis, R. Tasneen +6 more
2012Journal of Infectious Diseases256 citations Open access
Semantic Scholar
Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model
Kathy N. Williams, Charles K. Stover, T. Zhu, R. Tasneen +3 more
2008Antimicrobial Agents and Chemotherapy197 citations Open access
Semantic Scholar
Powerful Bactericidal and Sterilizing Activity of a Regimen Containing PA-824, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis
E. Nuermberger, S. Tyagi, R. Tasneen, Kathy N. Williams +3 more
2008Antimicrobial Agents and Chemotherapy189 citations Open access
Semantic Scholar
Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis
R. Tasneen, Si-Yang Li, C. Peloquin, Dinesh Taylor +4 more
2011Antimicrobial Agents and Chemotherapy186 citations Open access
Semantic Scholar
Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis
I. Rosenthal, R. Tasneen, C. Peloquin, Ming Zhang +5 more
2012Antimicrobial Agents and Chemotherapy148 citations Open access
Semantic Scholar
Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis.
Kathy N. Williams, S. J. Brickner, C. Stover, T. Zhu +5 more
2009American Journal of Respiratory and Critical Care Medicine130 citations
Semantic Scholar
Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis
R. Tasneen, Fabrice Betoudji, S. Tyagi, Si-Yang Li +7 more
2015Antimicrobial Agents and Chemotherapy123 citations Open access
Semantic Scholar
Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis
Jian Xu, Si-Yang Li, D. Almeida, R. Tasneen +6 more
2019Antimicrobial Agents and Chemotherapy99 citations Open access
Semantic Scholar
Enhanced Bactericidal Activity of Rifampin and/or Pyrazinamide When Combined with PA-824 in a Murine Model of Tuberculosis
R. Tasneen, S. Tyagi, Kathy N. Williams, J. Grosset +1 more
2008Antimicrobial Agents and Chemotherapy97 citations Open access
Semantic Scholar
Paradoxical Effect of Isoniazid on the Activity of Rifampin-Pyrazinamide Combination in a Mouse Model of Tuberculosis
D. Almeida, E. Nuermberger, R. Tasneen, I. Rosenthal +4 more
2009Antimicrobial Agents and Chemotherapy95 citations Open access
Semantic Scholar
Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis
Si-Yang Li, R. Tasneen, S. Tyagi, H. Soni +3 more
2017Antimicrobial Agents and Chemotherapy88 citations Open access
Semantic Scholar
Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9
A. Ordonez, R. Tasneen, Supriya Pokkali, Ziyue Xu +5 more
2016Disease Models & Mechanisms67 citations Open access
Semantic Scholar
Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis
R. Tasneen, Kathy N. Williams, O. Amoabeng, Austin Minkowski +3 more
2014Antimicrobial Agents and Chemotherapy62 citations Open access
Semantic Scholar
Comparison of the ‘Denver regimen’ against acute tuberculosis in the mouse and guinea pig
Z. Ahmad, E. Nuermberger, R. Tasneen, M. Pinn +4 more
2010Journal of Antimicrobial Chemotherapy53 citations Open access
Semantic Scholar
GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment
E. Nuermberger, María S. Martínez-Martínez, O. Sanz, Beatriz Urones +27 more
2022bioRxiv45 citations Open access
Semantic Scholar
Verapamil Increases the Bioavailability and Efficacy of Bedaquiline but Not Clofazimine in a Murine Model of Tuberculosis
Jian Xu, R. Tasneen, C. Peloquin, D. Almeida +4 more
2017Antimicrobial Agents and Chemotherapy43 citations Open access
Semantic Scholar
Impact of Clofazimine Dosing on Treatment Shortening of the First-Line Regimen in a Mouse Model of Tuberculosis
Nicole C. Ammerman, Rosemary V. Swanson, Elaine Bautista, D. Almeida +17 more
2018Antimicrobial Agents and Chemotherapy40 citations Open access
Semantic Scholar
In Vivo-Selected Pyrazinoic Acid-Resistant Mycobacterium tuberculosis Strains Harbor Missense Mutations in the Aspartate Decarboxylase PanD and the Unfoldase ClpC1
Pooja Gopal, R. Tasneen, Michelle Yee, J. Lanoix +6 more
2017ACS Infectious Diseases37 citations Open access
Semantic Scholar
In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis
A. Kaushik, Nicole C. Ammerman, R. Tasneen, Elizabeth Story-Roller +4 more
2017Journal of Antimicrobial Chemotherapy34 citations Open access
Semantic Scholar
Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models
R. Tasneen, Andrew Garcia, P. Converse, M. Zimmerman +7 more
2021bioRxiv27 citations Open access
Semantic Scholar
Mechanistic Modeling of Mycobacterium tuberculosis Infection in Murine Models for Drug and Vaccine Efficacy Studies
Nan Zhang, Natasha Strydom, S. Tyagi, H. Soni +3 more
2020Antimicrobial Agents and Chemotherapy26 citations Open access
Semantic Scholar
Preserved Efficacy and Reduced Toxicity with Intermittent Linezolid Dosing in Combination with Bedaquiline and Pretomanid in a Murine Tuberculosis Model
Kristina M. Bigelow, R. Tasneen, Yong S. Chang, K. Dooley +1 more
2020Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
Telacebec for Ultrashort Treatment of Buruli Ulcer in a Mouse Model
D. Almeida, P. Converse, T. Omansen, S. Tyagi +3 more
2020Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer
P. Converse, D. Almeida, R. Tasneen, V. Saini +7 more
2018PLoS Neglected Tropical Diseases25 citations Open access
Semantic Scholar
Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments
Christian Dide-Agossou, A. A. Bauman, M. E. Ramey, K. Rossmassler +11 more
2021bioRxiv24 citations Open access
Semantic Scholar
Treatment-Shortening Effect of a Novel Regimen Combining Clofazimine and High-Dose Rifapentine in Pathologically Distinct Mouse Models of Tuberculosis
V. Saini, Nicole C. Ammerman, Yong S. Chang, R. Tasneen +4 more
2019Antimicrobial Agents and Chemotherapy23 citations Open access
Semantic Scholar
High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis
JP. Lanoix, R. Tasneen, P. O’Brien, J. Sarathy +5 more
2016Antimicrobial Agents and Chemotherapy21 citations Open access
Semantic Scholar
Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis
R. Tasneen, D. Mortensen, P. Converse, Michael E. Urbanowski +4 more
2021bioRxiv17 citations Open access
Semantic Scholar
Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen
N. Strydom, Jacqueline P. Ernest, Marjorie Imperial, B. Solans +14 more
2024Nature Communications15 citations Open access
Semantic Scholar
Efficacy of Long-Acting Bedaquiline Regimens in a Mouse Model of Tuberculosis Preventive Therapy.
A. Kaushik, Nicole C. Ammerman, R. Tasneen, S. Lachau-Durand +2 more
2021American Journal of Respiratory and Critical Care Medicine15 citations
Semantic Scholar
Advancing the Therapeutic Potential of Indoleamides for Tuberculosis
S. Lun, R. Tasneen, Tridib Chaira, J. Stec +9 more
2019Antimicrobial Agents and Chemotherapy15 citations Open access
Semantic Scholar
An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis
S. Karanika, James T. Gordy, Pranita Neupane, Theodoros Karantanos +14 more
2022bioRxiv14 citations Open access
Semantic Scholar
Contribution of direct InhA inhibitors to novel drug regimens in a mouse model of tuberculosis
L. Encinas, Si-Yang Li, Joaquin Rullas-Trincado, R. Tasneen +15 more
2024Antimicrobial Agents and Chemotherapy5 citations Open access
Semantic Scholar
Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment
S. Karanika, Tianyin Wang, A. Yilma, Jennie Ruelas Castillo +20 more
2024bioRxiv4 citations Open access
Semantic Scholar
Long-term Effects of Prenatal Arsenic Exposure from Gestational Day 9 to Birth on Lung, Heart, and Immune Outcomes in the C57BL/6 Mouse Model
K. A. Rychlik, E. Illingworth, I. Sanchez, S.E. Attreed +10 more
2023Toxicology Letters4 citations Open access
Semantic Scholar
Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model
Kristina M. Bigelow, R. Tasneen, Yong S. Chang, K. Dooley +1 more
2020bioRxiv4 citations Open access
Semantic Scholar
Immunodeficiency and Intermittent Dosing Promote Acquired Rifamycin Monoresistance in Murine Tuberculosis
Sang-Won Park, R. Tasneen, P. Converse, E. Nuermberger
2017Antimicrobial Agents and Chemotherapy3 citations Open access
Semantic Scholar
Reply to “Contradictory Results with High-Dosage Rifamycin in Mice and Humans”
E. Nuermberger, I. Rosenthal, R. Tasneen, C. Peloquin +3 more
2013Antimicrobial Agents and Chemotherapy3 citations Open access
Semantic Scholar
High concentration of recombinant murine interferon-beta enhances the growth of Orientia (formerly Rickettsia) tsutsugamushi Gilliam in mouse L929 cells.
R. Tasneen, K. Yoshiie, T. Ohkawa, H. Oda
1997Acta virologica3 citations
Semantic Scholar
Hyaluronidase impacts exposures of long-acting injectable paliperidone palmitate in rodent models
H. Pertinez, Amit Kaushik, P. Curley, Usman Arshad +12 more
2024bioRxiv2 citations Open access
Semantic Scholar
A Guinea Pig Model of TB Chemotherapy.
Z. Ahmad, M. Pinn, R. Tasneen, Kathy N. Williams +3 more
2009Asian Test Symposium1 citations
Semantic Scholar
Immunotherapy targeting drug-tolerant Mycobacterium tuberculosis persisters accelerates tuberculosis cure in preclinical models
S. Karanika, Tianyin Wang, A. Yilma, Jennie Ruelas Castillo +22 more
2026Journal of Clinical Investigation0 citations Open access
Semantic Scholar
Direct inhibitors of InhA with efficacy similar or superior to isoniazid in novel drug regimens for tuberculosis
L. Encinas, Si-Yang Li, Joaquin Rullas-Trincado, R. Tasneen +15 more
2024bioRxiv0 citations Open access
Semantic Scholar
S17-02 The Long-term Impact of Perinatal Exposures on Susceptibility to Immune-mediated Diseases
K. A. Rychlik, E. J. Illingworth, S. E. Attreed, S. S. Sanchez +15 more
2023Toxicology Letters0 citations
Semantic Scholar
The Antagonistic Effect Of Isoniazid On Rifampin-Pyrazinamide In Experimental Murine Tuberculosis (TB) Requires Functional Bacterial Catalase-Peroxidase (KatG)
R. Tasneen, D. Almeida, Kathy N. Williams, J. Grosset +1 more
2010Asian Test Symposium0 citations
Semantic Scholar
PA-824, moxifloxacin and pyrazinamide in the murine model of
E. Nuermberger, S. Tyagi, R. Tasneen, Kathy N. Williams +3 more
20080 citations
Semantic Scholar
High concentration of recombinant murine interferon-β enhances the growth of Orientia(formerly Rickettsia)tsutsugamushi Gilliam in mouse L929 cells(高濃度のリコンビナントマウスインターフェロンーβはマウス由来L929細胞におけるOrientia(旧名Rickettsia)tsutsugamushiの増殖を促進する)
R. Tasneen
19970 citations
Semantic Scholar
1 Novel regimens of bedaquiline-pyrazinamide combined with moxifloxacin, rifabutin, 1 delamanid and/or OPC-167832 in murine tuberculosis models
R. Tasneen, Andrew Garcia, P. Converse, Matthew D. Zimmerman +9 more
0 citations
Semantic Scholar

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E. Nuermberger×44
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S. Tyagi×14
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S. Tyagi — researcher profile on SciRah
J. Grosset×14
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P. Converse×14
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Kathy N. Williams

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K. Mdluli — researcher profile on SciRah

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D. Almeida — researcher profile on SciRah

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H. Soni — researcher profile on SciRah

Nicole C. Ammerman×6

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Nicole C. Ammerman — researcher profile on SciRah

I. Rosenthal×5

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I. Rosenthal — researcher profile on SciRah