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Laura F. Newell · SciRah

Researcher profile · Semantic Scholar

Laura F. Newell

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Laura F. Newell — researcher profile on SciRah

h-index: 21
Works: 93
Citations: 2,943

Most-cited papers

CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia
J. Lancet, Geoffrey L. Uy, J. Cortes, Laura F. Newell +17 more
2018Journal of Clinical Oncology838 citations Open access
Semantic Scholar
Advances in acute myeloid leukemia
Laura F. Newell, R. Cook
2021British medical journal411 citations Open access
Semantic Scholar
Identification of interleukin-1 by functional screening as a key mediator of cellular expansion and disease progression in acute myeloid leukemia
Alyssa Carey, David K. Edwards, C. Eide, Laura F. Newell +10 more
2017Cell Reports247 citations Open access
Semantic Scholar
BMPs signal alternately through a SMAD or FRAP–STAT pathway to regulate fate choice in CNS stem cells
P. Rajan, David M. Panchision, Laura F. Newell, R. Mckay
2003Journal of Cell Biology233 citations Open access
Semantic Scholar
CPX-351 versus 7+3 cytarabine and daunorubicin chemotherapy in older adults with newly diagnosed high-risk or secondary acute myeloid leukaemia: 5-year results of a randomised, open-label, multicentre, phase 3 trial.
J. Lancet, Geoffrey L. Uy, Laura F. Newell, Tara L. Lin +12 more
2021The Lancet Haematology194 citations
Semantic Scholar
Final results of a phase III randomized trial of CPX-351 versus 7+3 in older patients with newly diagnosed high risk (secondary) AML.
J. Lancet, Geoffrey L. Uy, J. Cortes, Laura F. Newell +16 more
2016146 citations
Semantic Scholar
Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia
C. Lachowiez, Nicola Long, Jennifer N. Saultz, A. Gandhi +14 more
2022Blood Advances94 citations Open access
Semantic Scholar
Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells.
A. Kariminia, S. Holtan, S. Ivison, J. Rozmus +27 more
2016Blood79 citations Open access
Semantic Scholar
Circulating Angiogenic Factors Associated with Response and Survival in Patients with Acute Graft-Versus-Host Disease: Results from BMT CTN 0302 and 0802
S. Holtan, M. Verneris, K. Schultz, Laura F. Newell +10 more
2015Biology of Blood and Marrow Transplantation59 citations Open access
Semantic Scholar
Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors.
S. Holtan, N. Khera, J. Levine, X. Chai +30 more
2016Blood54 citations Open access
Semantic Scholar
Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells.
G. Humphrey, Yong-Hong Wang, T. Hirai, R. Padmanabhan +4 more
2008Differentiation; research in biological diversity52 citations Open access
Semantic Scholar
Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802.
S. Holtan, T. Defor, A. Panoskaltsis-Mortari, N. Khera +33 more
2018Blood Advances41 citations Open access
Semantic Scholar
Dissection of the Human Multipotent Adult Progenitor Cell Secretome by Proteomic Analysis
G. Burrows, W. Van't Hof, Laura F. Newell, Ashok P. Reddy +7 more
2013Stem Cells Translational Medicine35 citations Open access
Semantic Scholar
Characteristics of Chronic GVHD after Cord Blood Transplantation
Laura F. Newell, M. E. Flowers, T. Gooley, F. Milano +3 more
2013Bone Marrow Transplantation34 citations Open access
Semantic Scholar
Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML
Geoffrey L. Uy, Laura F. Newell, Tara L. Lin, S. Goldberg +4 more
2022Blood Advances32 citations Open access
Semantic Scholar
Placental Growth Factor: What Hematologists Need to Know
Laura F. Newell, S. Holtan
2016Blood reviews32 citations Open access
Semantic Scholar
CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy.
J. Tuscano, J. Kato, D. Pearson, C. Xiong +4 more
2012Cancer Research29 citations Open access
Semantic Scholar
Adult adherent stromal cells in the management of graft-versus-host disease
Laura F. Newell, R. Deans, R. Maziarz
2014Expert Opinion on Biological Therapy28 citations
Semantic Scholar
Diurnal stability of cell-free DNA and cell-free RNA in human plasma samples
Josiah T. Wagner, Hyun Ji Kim, Katie Johnson-Camacho, Taylor Kelley +3 more
2020Scientific Reports25 citations Open access
Semantic Scholar
Engrafted donor-derived clonal hematopoiesis after allogenic hematopoietic cell transplantation is associated with chronic GVHD requiring immunosuppressive therapy, but no adverse impact on OS or relapse.
Laura F. Newell, Todd P. Williams, J. Liu, Yung-Dong Yu +14 more
2021Transplantation and Cellular Therapy22 citations Open access
Semantic Scholar
Survival Following Allogeneic Hematopoietic Cell Transplantation in Older High-Risk Acute Myeloid Leukemia Patients Initially Treated with CPX-351 Liposome Injection Versus Standard Cytarabine and Daunorubicin: Subgroup Analysis of a Large Phase III Trial
J. Lancet, A. Hoering, Geoffrey L. Uy, J. Cortes +16 more
201621 citations
Semantic Scholar
Early CD3 Peripheral Blood Chimerism Predicts the Long-Term Engrafting Unit Following Myeloablative Double Cord Blood Transplantation
Laura F. Newell, F. Milano, I. Nicoud, S. Pereira +3 more
2012Biology of Blood and Marrow Transplantation21 citations Open access
Semantic Scholar
Five-year final results of a phase III study of CPX-351 versus 7+3 in older adults with newly diagnosed high-risk/secondary AML.
J. Lancet, Geoffrey L. Uy, Laura F. Newell, Tara L. Lin +13 more
202018 citations
Semantic Scholar
A phase 2 study to assess the pharmacokinetics and pharmacodynamics of CPX-351 and its effects on cardiac repolarization in patients with acute leukemias
Tara L. Lin, Laura F. Newell, R. Stuart, L. Michaelis +9 more
2019Cancer Chemotherapy and Pharmacology18 citations Open access
Semantic Scholar
TNF Polymorphism Affects Transplant Outcome in Patients with MDS but not with CML, Independent of the Presence of HLA-DR15
Laura F. Newell, T. Gooley, J. A. Hansen, D. Stirewalt +2 more
2010Biology of Blood and Marrow Transplantation16 citations Open access
Semantic Scholar
Overall survival (OS) with CPX-351 versus 7+3 in older adults with newly diagnosed, therapy-related acute myeloid leukemia (tAML): Subgroup analysis of a phase III study.
J. Lancet, D. Rizzieri, G. Schiller, R. Stuart +9 more
201714 citations
Semantic Scholar
The Bispecific Anti-CD20/CD22 Antibody (Bs20x22) Has More Lymphomacidal Activity Than the Parent Antibodies Both Alone or In Combination
Laura F. Newell, J. Tuscano, Yunpeng Ma, Shiloh M. Martin +1 more
201012 citations
Semantic Scholar
Acute GVHD: think before you treat.
Laura F. Newell, S. Holtan
2021Hematology. American Society of Hematology. Education Program10 citations Open access
Semantic Scholar
Analysis of Efficacy By Age for Patients Aged 60-75 with Untreated Secondary Acute Myeloid Leukemia (AML) Treated with CPX-351 Liposome Injection Versus Conventional Cytarabine and Daunorubicin in a Phase III Trial
B. C. Medeiros, J. Lancet, J. Cortes, Laura F. Newell +16 more
201610 citations
Semantic Scholar
CPX-351 ((Cytarabine:Daunorubicin) Liposome Injection, (Vyxeos)) Does Not Prolong Qtcf Intervals, Requires No Dose Adjustment for Impaired Renal Function and Induces High Rates of Complete Remission in Acute Myeloid Leukemia
Tara L. Lin, Laura F. Newell, R. Stuart, L. Michaelis +6 more
201510 citations
Semantic Scholar
Efficacy and Safety of CPX-351 Versus 7+3 in Older Adults with Secondary Acute Myeloid Leukemia: Combined Subgroup Analysis of Phase 2 and Phase 3 Studies
J. Lancet, E. Ritchie, Geoffrey L. Uy, B. C. Medeiros +16 more
20178 citations
Semantic Scholar
Efficacy and Safety of CPX-351 Versus 7+3 in a Subgroup of Older Patients with Newly Diagnosed Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Enrolled in a Phase 3 Study
D. Ryan, Geoffrey L. Uy, J. Cortes, Laura F. Newell +14 more
2018Blood7 citations Open access
Semantic Scholar
Allogeneic transplantation outcomes amongst a contemporary cohort of high-risk myelodysplastic syndrome and acute myeloid leukemia patients aged ≥70 years.
C. Lachowiez, R. Cook, Brandon Hayes-Lattin, R. Maziarz +6 more
2019Hematology/Oncology and Stem Cell Therapy6 citations Open access
Semantic Scholar
Feasibility and Cost Analysis of Day 4 Granulocyte Colony-Stimulating Factor Mobilized Peripheral Blood Progenitor Cell Collection from HLA-Matched Sibling Donors
Laura F. Newell, Kelsea M. Shoop, R. Knight, S. Murray +10 more
2019Cytotherapy6 citations Open access
Semantic Scholar
Subanalysis of Patients with Secondary Acute Myeloid Leukemia (sAML) with Refractory Anemia with Excess of Blasts in Transformation (RAEB-T) Enrolled in a Phase 3 Study of CPX-351 Versus Conventional 7 + 3 Cytarabine and Daunorubicin
Tara L. Lin, Geoffrey L. Uy, M. Wieduwilt, Laura F. Newell +13 more
20186 citations Open access
Semantic Scholar
Donor and Recipient Plasma Follistatin Levels are Associated with Acute Graft-versus-Host Disease in Blood and Marrow Transplant Clinical Trials Network 0402
L. Turcotte, T. Defor, Laura F. Newell, C. Cutler +11 more
2017Bone Marrow Transplantation6 citations Open access
Semantic Scholar
CPX-351 Pharmacokinetics and Safety in Adults with Hematologic Malignancies and Renal Function Impairment: Phase 1 Trial
S. Solomon, Bayard L. Powell, Jamie L. Koprivnikar, Catherine Lai +9 more
2024Cancers5 citations Open access
Semantic Scholar
Follistatin and Soluble Endoglin Predict 1-year Non-Relapse Mortality after Allogeneic Hematopoietic Cell Transplant
Laura F. Newell, T. Defor, C. Cutler, M. Verneris +9 more
2019Biology of Blood and Marrow Transplantation5 citations Open access
Semantic Scholar
Overall survival (OS) and stem cell transplant (SCT) in patients with FLT3 mutations treated with CPX-351 versus 7+3: Subgroup analysis of a phase III study of older adults with newly diagnosed, high-risk acute myeloid leukemia (AML).
B. C. Medeiros, D. Hogge, Laura F. Newell, D. Bixby +10 more
20175 citations
Semantic Scholar
Analysis of Transplantation Rate and Overall Treatment Efficacy by Age for Patients Aged 60 to 75 with Untreated Secondary Acute Myeloid Leukemia (AML) Given CPX-351 Liposome Injection Versus Conventional Cytarabine and Daunorubicin in a Phase III Trial
J. Lancet, Geoffrey L. Uy, J. Cortes, Laura F. Newell +16 more
20175 citations Open access
Semantic Scholar
Stable Long-Term Pulmonary Function after Myeloablative Double Cord Blood Transplant
F. Milano, J. Chien, Ivy Riffkin, J. Gutman +3 more
2011Biology of Blood and Marrow Transplantation5 citations Open access
Semantic Scholar
Long-Term Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients Enrolled in CPX-351-301, a Randomized Phase 3 Study of CPX-351 Versus 7+3 in Older Adults with Newly Diagnosed, High-Risk and/or Secondary AML
Geoffrey L. Uy, Laura F. Newell, Tara L. Lin, S. Goldberg +4 more
2020Transplantation and Cellular Therapy4 citations Open access
Semantic Scholar
Outcomes in Patients with Therapy-Related Acute Myeloid Leukemia (t-AML) Who Achieved Remission with CPX-351 Versus 7+3: Phase 3 Exploratory Analysis
J. Lancet, D. Rizzieri, G. Schiller, S. Solomon +5 more
2019Biology of Blood and Marrow Transplantation4 citations Open access
Semantic Scholar
Dissection of the Human Multipotent Adult Progenitor Cell (MAPC) Secretome by Proteomic Analysis
R. Maziarz, Laura F. Newell, A. Bogaerts, J. Pinxteren +2 more
20134 citations Open access
Semantic Scholar
Outcomes in Patients with Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Who Achieved Remission with CPX-351 Versus 7+3: Phase 3 Exploratory Analysis
D. Ryan, Laura F. Newell, E. Ritchie, S. Strickland +8 more
2019Blood3 citations Open access
Semantic Scholar
Rates of Adverse Events per Patient-Year in a Randomized, Phase 3 Study of CPX-351 Versus 7+3 in Older Adults with Newly Diagnosed, Treatment-Related Acute Myeloid Leukemia (AML) or AML with Myelodysplasia-Related Changes
B. C. Medeiros, J. Lancet, J. Cortes, Laura F. Newell +15 more
20173 citations
Semantic Scholar
Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802
S. Holtan, T. Defor, J. Pidala, N. Khera +35 more
20173 citations Open access
Semantic Scholar
Angiogenic Factors, Inflammation, and Outcomes in Myeloablative Allogeneic Hematopoietic Cell Transplantation: A Biomarker Analysis of Gvhd Prophylaxis in Blood and Marrow Transplant Clinical Trials Network Protocol (BMT CTN) 0402
Laura F. Newell, M. Verneris, A. Panoskaltsis-Mortari, T. Defor +6 more
20163 citations Open access
Semantic Scholar
Tissue Expression of Placental Growth Factor in Acute Graft Versus Host Disease after Hematopoietic Stem Cell Transplantation
Jessica T. Leonard, Laura F. Newell, Guang Fan, S. Holtan
20143 citations
Semantic Scholar
Follistatin and Endoglin: Potential Biomarkers of Endothelial Damage and Non-Relapse Mortality after Myeloablative Allogeneic Hematopoietic Cell Transplantation in Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0402
Laura F. Newell, T. Defor, C. Cutler, M. Verneris +8 more
20162 citations Open access
Semantic Scholar

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J. Lancet×16
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Tara L. Lin×15
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Geoffrey L. Uy×14
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