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T. Falzone · SciRah

Researcher profile · Semantic Scholar

T. Falzone

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T. Falzone — researcher profile on SciRah

h-index: 21
Works: 47
Citations: 3,290

Most-cited papers

Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease
G. Stokin, C. Lillo, T. Falzone, R. Brusch +7 more
2005Science1,229 citations
Semantic Scholar
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.
M. Rubinstein, T. Phillips, J. Bunzow, T. Falzone +11 more
1997Cell496 citations Open access
Semantic Scholar
Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?
Victorio Martin Pozo Devoto, T. Falzone
2017Disease Models & Mechanisms162 citations Open access
Semantic Scholar
Dopamine D4 Receptor-Deficient Mice Display Cortical Hyperexcitability
M. Rubinstein, C. Cepeda, R. S. Hurst, J. Flores-Hernández +8 more
2001Journal of Neuroscience141 citations Open access
Semantic Scholar
Mouse sperm begin to undergo acrosomal exocytosis in the upper isthmus of the oviduct
Florenza A. La Spina, Lis C. Puga Molina, Ana Romarowski, A. Vitale +4 more
2016Developmental Biology122 citations Open access
Semantic Scholar
Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear
T. Falzone, D. Gelman, Juan I. Young, D. Grandy +2 more
2002European Journal of Neuroscience109 citations Open access
Semantic Scholar
Axonal Stress Kinase Activation and Tau Misbehavior Induced by Kinesin-1 Transport Defects
T. Falzone, G. Stokin, C. Lillo, E. M. Rodrigues +3 more
2009Journal of Neuroscience102 citations Open access
Semantic Scholar
Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons
V. Lacovich, S. Espíndola, M. Alloatti, Victorio Martin Pozo Devoto +8 more
2017Journal of Neuroscience90 citations Open access
Semantic Scholar
αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson’s disease
Victorio Martin Pozo Devoto, N. Dimopoulos, M. Alloatti, M. B. Pardi +9 more
2017Scientific Reports89 citations Open access
Semantic Scholar
Role of neuronal activity and kinesin on tract tracing by manganese-enhanced MRI (MEMRI).
E. Bearer, T. Falzone, Xiaowei Zhang, O. Biris +2 more
2007NeuroImage88 citations Open access
Semantic Scholar
Authentic Cell-Specific and Developmentally Regulated Expression of Pro-Opiomelanocortin Genomic Fragments in Hypothalamic and Hindbrain Neurons of Transgenic Mice
Juan I. Young, Verónica Otero, Marcelo G. Cerdán, T. Falzone +3 more
1998Journal of Neuroscience85 citations Open access
Semantic Scholar
Differential mitochondrial roles for α-synuclein in DRP1-dependent fission and PINK1/Parkin-mediated oxidation
Thomas J. Krzystek, Rupkatha Banerjee, Layne Thurston, Jian-Qiao Huang +4 more
2021Cell Death and Disease64 citations Open access
Semantic Scholar
Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides.
G. Stokin, A. Almenar-Queralt, Shermali Gunawardena, E. M. Rodrigues +8 more
2008Human Molecular Genetics64 citations Open access
Semantic Scholar
Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies.
T. Falzone, Shermali Gunawardena, David F. McCleary, G. Reis +1 more
2010Human Molecular Genetics63 citations Open access
Semantic Scholar
Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function
M. G. Otero, M. Alloatti, L. Cromberg, A. Almenar-Queralt +5 more
2014Journal of Cell Science51 citations Open access
Semantic Scholar
Enhanced expression of dopamine D1 and glutamate NMDA receptors in dopamine D4 receptor knockout mice
Lu Gan, T. Falzone, Ke-Hong Zhang, M. Rubinstein +2 more
2007Journal of Molecular Neuroscience47 citations Open access
Semantic Scholar
Quantitative analysis of the dopamine D4 receptor in the mouse brain
M. Defagot, T. Falzone, Malcolm J. Low, D. Grandy +2 more
2000Journal of Neuroscience Research41 citations
Semantic Scholar
UV Irradiation Accelerates Amyloid Precursor Protein (APP) Processing and Disrupts APP Axonal Transport
A. Almenar-Queralt, T. Falzone, Zhou-Xin Shen, C. Lillo +8 more
2014Journal of Neuroscience31 citations Open access
Semantic Scholar
Accurate spatial and temporal transgene expression driven by a 3.8‐kilobase promoter of the bovine β‐casein gene in the lactating mouse mammary gland
Marcelo G. Cerdán, Juan I. Young, Esilda Zino, T. Falzone +3 more
1998Molecular Reproduction and Development28 citations
Semantic Scholar
Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance
T. Saez, Iván Fernandez Bessone, María S. Rodriguez, M. Alloatti +8 more
2020Development25 citations Open access
Semantic Scholar
Mitochondrial vulnerability to oxidation in human brain organoids modelling Alzheimer's disease.
M. Holubiec, M. Alloatti, B. Julieta, Greloni Francisco +5 more
2023Free Radical Biology & Medicine21 citations Open access
Semantic Scholar
Neuronal KIF5b deletion induces striatum‐dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
L. Cromberg, T. Saez, M. G. Otero, E. Tomasella +7 more
2019Journal of Neurochemistry16 citations Open access
Semantic Scholar
Hyperglycemia-induced mitochondrial abnormalities in autonomic neurons via the RAGE axis
Maria G. Otero, Nicolas Henao-Romero, Trevor M Krysak, M. Vu-Lu +5 more
2025Scientific Reports15 citations Open access
Semantic Scholar
Hippocampal to basal forebrain transport of Mn2+ is impaired by deletion of KLC1, a subunit of the conventional kinesin microtubule-based motor
C. S. Medina, O. Biris, T. Falzone, Xiaowei Zhang +2 more
2016NeuroImage15 citations Open access
Semantic Scholar
Modeling Alzheimer's Disease Using Human Brain Organoids.
Karina Karmirian, M. Holubiec, L. Goto-Silva, Ivan Fernandez Bessone +6 more
2023Methods in molecular biology14 citations
Semantic Scholar
DYRK1A Regulates the Bidirectional Axonal Transport of APP in Human-Derived Neurons
Iván Fernandez Bessone, Jordi Navarro, E. Martínez, Karina Karmirian +10 more
2022Journal of Neuroscience14 citations Open access
Semantic Scholar
Proteasome stress leads to APP axonal transport defects by promoting its amyloidogenic processing in lysosomes
M. G. Otero, Ivan Fernandez Bessone, A. Hallberg, L. Cromberg +5 more
2018Journal of Cell Science14 citations Open access
Semantic Scholar
Imaging amyloid precursor protein in vivo: an axonal transport assay.
T. Falzone, G. Stokin
2012Methods in molecular biology13 citations Open access
Semantic Scholar
SOX‐11 regulates LINE‐1 retrotransposon activity during neuronal differentiation
Andrés J. Orqueda, C. R. Gatti, M. F. Ogara, T. Falzone
2018FEBS Letters12 citations Open access
Semantic Scholar
Swedish Alzheimer’s disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways
Monica Feole, Victorio Martin Pozo Devoto, N. Dragišić, Cayetana Arnaiz +7 more
2024Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Tau reduction with artificial microRNAs modulates neuronal physiology and improves tauopathy phenotypes in mice
C. Facal, Iván Fernández Bessone, J. Muñiz, A. Pereyra +12 more
2024Molecular Therapy6 citations Open access
Semantic Scholar
Tetraspanin1 promotes NGF signaling by controlling TrkA receptor proteostasis
Facundo Ferrero Restelli, P. Fontanet, Ana Paula De Vincenti, T. Falzone +2 more
2019Cellular and Molecular Life Sciences5 citations Open access
Semantic Scholar
Early Unguided Human Brain Organoid Neurovascular Niche Modeling into the Permissive Chick Embryo Chorioallantoic Membrane.
Luciano Fiore, Jan Arderiu, Andrea Martí-Sarrias, Isabel Turpín +8 more
2024Journal of Visualized Experiments3 citations Open access
Semantic Scholar
Tau conditional reduction in human‐derived neurons exposes novel tau‐associated functions in electrical activity and axonal transport
Ivan Fernandez Bessone, Ana Damianich, Olivia Pedroncini, M. Holubiec +4 more
2021Alzheimer's & Dementia2 citations
Semantic Scholar
Methods for Quantitative Analysis of Axonal Cargo Transport.
M. Alloatti, L. Bruno, T. Falzone
2018Methods in molecular biology2 citations Open access
Semantic Scholar
Tau isoforms imbalance impairs the axonal transport of the amyloid precursor protein in human neurons.
V. Lacovich, S. Espíndola, M. Alloatti, Victorio Martin Pozo Devoto +8 more
2016Journal of Neuroscience2 citations Open access
Semantic Scholar
Tau isoforms modulate the axon initial segment controlling axonal trafficking and neuronal excitability
Cayetana Arnaiz, Gonzalo Escalante, Lautaro Rodriguez Donghi, M. Holubiec +12 more
2026bioRxiv0 citations Open access
Semantic Scholar
Huntingtin is a cell-autonomous regulator of neuropeptide trafficking and clock output
Agustina Bruno-Vignolo, Cayetana Arnaiz, Florencia Fernández-Chiappe, Ana Ricciuti +10 more
2026bioRxiv0 citations
Semantic Scholar
Prospective Longitudinal Cohort of Argentinean Patients with Progressive Supranuclear Palsy: A Platform for Epidemiological and Translational Research
Blas Couto, María Jose Angel Pinto, M. Avale, T. Falzone +9 more
2025Alzheimer's & Dementia0 citations Open access
Semantic Scholar
APP mutations give rise to redox related mitochondrial alterations
M. Holubiec, Francisco Greloni, Julieta Bianchelli, Cayetana Arnaiz +2 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
DYRK1A role in microtubule-based axonal transport regulates the retrograde dynamics of APP vesicles in human neurons
I. Bessone, Karina Karmirian, L. Goto-Silva, M. Holubiec +5 more
2021bioRxiv0 citations Open access
Semantic Scholar
Most sperm undergo acrosomal exocytosis in the upper oviductal isthmus 1
Florenza A. La Spina, Ana Romarowski, Lis C. Puga Molina, T. Falzone +3 more
20160 citations
Semantic Scholar
P4‐013: Perturbation of 3R/4R tau ratio impairs app axonal transport in neurons derived from human embryonic stem cells (HESC)
V. Lacovich, M. Alloatti, M. Avale, S. Espíndola +6 more
20150 citations Open access
Semantic Scholar
O3‐04‐05: Coordinated proteasome and lysosome retrograde axonal transport is regulated by kinesin‐1 clustering at projection ends
M. G. Otero, L. Cromberg, T. Falzone
20120 citations
Semantic Scholar
Neonatal dopamine depletion in mice induces behavioral changes which involve the dopamine D4 receptor
M. Avale, S. Nemirovsky, T. Falzone, M. Rubinstein
20030 citations
Semantic Scholar
Normal Spatial Learning and Improved Spatial Working Memory in Mice () Lacking Dopamine D4 Receptors
T. Falzone, Elena M. Avale, D. Gelman, M. Rubinstein
20010 citations
Semantic Scholar
Normal Spatial Learning and Improved Spatial Working Memory in Mice (Mus musculus) Lacking Dopamine D4 Receptors
T. Falzone, Elena M. Avale, D. Gelman, M. Rubinstein
2001International Journal of Comparative Psychology0 citations Open access
Semantic Scholar

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M. Alloatti×12
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Victorio Martin Pozo Devoto×8
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L. Cromberg — researcher profile on SciRah

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T. Saez — researcher profile on SciRah

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M. Holubiec — researcher profile on SciRah

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D. Gelman — researcher profile on SciRah

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