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Amit Budhraja · SciRah

Researcher profile · Semantic Scholar

Amit Budhraja

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Amit Budhraja — researcher profile on SciRah

h-index: 23
Works: 40
Citations: 2,155

Most-cited papers

Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways
P. Pratheeshkumar, Amit Budhraja, Young-Ok Son, Xin Wang +9 more
2012PLoS ONE282 citations Open access
Semantic Scholar
Cancer Prevention with Promising Natural Products: Mechanisms of Action and Molecular Targets
P. Pratheeshkumar, C. Sreekala, Zhuo Zhang, Amit Budhraja +8 more
2012Anti-Cancer Agents in Medicinal Chemistry167 citations Open access
Semantic Scholar
Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells
Young-Ok Son, Xin Wang, J. Hitron, Zhuo Zhang +5 more
2011Toxicology and Applied Pharmacology141 citations Open access
Semantic Scholar
Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study
Seth E. Karol, T. Alexander, Amit Budhraja, S. Pounds +13 more
2020The Lancet Oncology136 citations Open access
Semantic Scholar
Luteolin Inhibits Human Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis
P. Pratheeshkumar, Young-Ok Son, Amit Budhraja, Xin Wang +10 more
2012PLoS ONE128 citations Open access
Semantic Scholar
Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling
Young-Ok Son, Lei Wang, P. Poyil, Amit Budhraja +4 more
2012Toxicology and Applied Pharmacology124 citations Open access
Semantic Scholar
NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium.
Xin Wang, Young-Ok Son, Qingshan Chang, Lijuan Sun +7 more
2011Toxicological Sciences117 citations Open access
Semantic Scholar
Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways
N. Gao, Amit Budhraja, Sen-Ping Cheng, E-hu Liu +5 more
2011Cell Death and Disease104 citations Open access
Semantic Scholar
Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo via inactivation of Akt and activation of JNK
Amit Budhraja, N. Gao, Zhuo Zhang, Young-Ok Son +7 more
2011Molecular Cancer Therapeutics96 citations Open access
Semantic Scholar
Quercetin induces tumor-selective apoptosis through down-regulation of Mcl-1 and activation of Bax
Sen-Ping Cheng, N. Gao, Zhuo Zhang, Gang Chen +6 more
2010Clinical Cancer Research93 citations Open access
Semantic Scholar
Role of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cells
Zhuo Zhang, P. Pratheeshkumar, Amit Budhraja, Young-Ok Son +2 more
2014Biochemical and Biophysical Research Communications - BBRC65 citations Open access
Semantic Scholar
Reactive oxygen species mediate arsenic induced cell transformation and tumorigenesis through Wnt/β-catenin pathway in human colorectal adenocarcinoma DLD1 cells.
Zhuo Zhang, Xin Wang, Sen-Ping Cheng, Lijuan Sun +9 more
2011Toxicology and Applied Pharmacology63 citations
Semantic Scholar
Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer.
Taekyu Lee, P. Christov, Subrata Shaw, J. C. Tarr +23 more
2019Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis
Guo-Bing Li, Jing Zhou, Amit Budhraja, Xiao-ye Hu +7 more
2014OncoTarget61 citations Open access
Semantic Scholar
Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo
N. Gao, Amit Budhraja, Sen-Ping Cheng, E-hu Liu +6 more
2011Apoptosis61 citations
Semantic Scholar
Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti‐leukaemic activity in nude mice through the PKB pathway
N. Gao, Sen-Ping Cheng, Amit Budhraja, Ziyi Gao +9 more
2012British Journal of Pharmacology60 citations Open access
Semantic Scholar
Discovery and Biological Characterization of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors
Taekyu Lee, Zhiguo Bian, Bin Zhao, L. Hogdal +20 more
2016FEBS Letters56 citations Open access
Semantic Scholar
Epithelial-Mesenchymal Transition During Oncogenic Transformation Induced by Hexavalent Chromium Involves Reactive Oxygen Species-Dependent Mechanisms in Lung Epithelial Cells
Song-Ze Ding, Yu-Xiu Yang, Xiu-Ling Li, Audrey Michelli-Rivera +8 more
2013Toxicology and Applied Pharmacology49 citations Open access
Semantic Scholar
Induction of Apoptosis in Human Leukemia Cells by Grape Seed Extract Occurs via Activation of JNK
N. Gao, Amit Budhraja, Sen-Ping Cheng, Hua Yao +2 more
2009Clinical Cancer Research47 citations Open access
Semantic Scholar
Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines
B. Koss, J. Ryan, Amit Budhraja, Katherine B. Szarama +6 more
2016OncoTarget31 citations Open access
Semantic Scholar
Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells through hypoxia-inducible factor 1 alpha pathway.
Lei Wang, Young-Ok Son, Song-Ze Ding, Xin Wang +8 more
2012Toxicological Sciences31 citations Open access
Semantic Scholar
MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
Michelle S. Prew, Utsarga Adhikary, D. Choi, Erika P. Portero +7 more
2022Cell Reports30 citations Open access
Semantic Scholar
Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL+ B-Lineage Acute Lymphoblastic Leukemia
Amit Budhraja, Meghan E. Turnis, Michelle L. Churchman, Anisha Kothari +7 more
2017Clinical Cancer Research30 citations Open access
Semantic Scholar
3, 3′-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process
N. Gao, Sen-Ping Cheng, Amit Budhraja, E-hu Liu +6 more
2012PLoS ONE23 citations Open access
Semantic Scholar
The Heme-regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics
Kaitlyn H. Smith, Amit Budhraja, J. Lynch, K. Roberts +7 more
2020Molecular Cancer Research20 citations Open access
Semantic Scholar
Apigenin suppresses migration and invasion of transformed cells through down-regulation of C-X-C chemokine receptor 4 expression
Lei Wang, Lisha Kuang, J. Hitron, Young-Ok Son +8 more
2013Toxicology and Applied Pharmacology20 citations Open access
Semantic Scholar
The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells.
Young-Ok Son, J. Hitron, Sen-Ping Cheng, Amit Budhraja +4 more
2011Toxicological Sciences15 citations Open access
Semantic Scholar
Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models.
T. Ling, Walter H. Lang, J. E. Craig, Malia B. Potts +6 more
2019Journal of Natural Products10 citations
Semantic Scholar
Anti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cells
Yu-Xiu Yang, Xiu-Ling Li, Lei Wang, Shuang-Yin Han +9 more
2013International Journal of Oncology10 citations Open access
Semantic Scholar
Activity of Venetoclax Against Relapsed Acute Undifferentiated Leukemia
Kenneth J. Caldwell, Amit Budhraja, J. Opferman, C. Pui +2 more
2021Cancer7 citations Open access
Semantic Scholar
Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents.
T. Ling, Julie Maier, Sourav Das, Amit Budhraja +6 more
2019European journal of medicinal chemistry7 citations Open access
Semantic Scholar
Caffeine and theobromine identifications in post-race urines: threshold levels and regulatory significance of such identifications.
Amit Budhraja, F. Camargo, C. Hughes, A. Lehner +4 more
20077 citations
Semantic Scholar
Abstract 4593: Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in athymic nude mice
Amit Budhraja, N. Gao, Zhouhai Zhang, Young-Ok Son +4 more
20112 citations
Semantic Scholar
POSTER: ALL-594 Preclinical Assessment of Dual FLT3 and BCL-2 Inhibition in Lineage Ambiguous Leukemia
L. Montefiori, I. Iacobucci, Amit Budhraja, J. Moore +9 more
2023Clinical Lymphoma, Myeloma & Leukemia1 citations
Semantic Scholar
ALL-090 Highly Effective Combination of FLT3 and BCL2 Inhibitors in a Preclinical Model of Lineage Ambiguous Leukemia.
L. Montefiori, Ilaria Lacobucci, Amit Budhraja, J. Moore +11 more
2022Clinical Lymphoma, Myeloma & Leukemia1 citations
Semantic Scholar
Understanding How Cellular Metabolism Affects Clofarabine Treatment in Acute Myeloid Leukemia
A. Gray, Yuzo Fukuda, Lauren Brakefield, Amit Budhraja +2 more
2023ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology0 citations Open access
Semantic Scholar
Expression of Concern: "The Dual Roles of c-Jun NH2-Terminal Kinase Signaling in Cr(VI)-Induced Apoptosis in JB6 Cells".
Young-Ok Son, J. Hitron, Sen-Ping Cheng, Amit Budhraja +4 more
2020Toxicological Sciences0 citations Open access
Semantic Scholar
Retraction: "Ethanol Enhances Tumor Angiogenesis In Vitro Induced by Low-Dose Arsenic in Colon Cancer Cells Through Hypoxia-Inducible Factor 1 Alpha Pathway".
Lei Wang, Young-Ok Son, Song-Ze Ding, Xin Wang +8 more
2020Toxicological Sciences0 citations Open access
Semantic Scholar
Heme-Sensing Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics
Kaitlyn H. Smith, Amit Budhraja, J. Lynch, K. Roberts +7 more
2020bioRxiv0 citations Open access
Semantic Scholar
Molecular mechanism of apigenin induced apoptosis in leukemia
Amit Budhraja
20120 citations
Semantic Scholar

Frequent co-authors

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Xiang-Lin Shi×21
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Xiang-Lin Shi — researcher profile on SciRah
Zhuo Zhang×18
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Zhuo Zhang — researcher profile on SciRah
Young-Ok Son×16
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Young-Ok Son — researcher profile on SciRah
J. Opferman×14
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×12

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Xin Wang — researcher profile on SciRah

Sen-Ping Cheng×11

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Sen-Ping Cheng — researcher profile on SciRah

Jeong-Chae Lee×10

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Lei Wang — researcher profile on SciRah

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Jia Luo — researcher profile on SciRah

Song-Ze Ding×8

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Song-Ze Ding — researcher profile on SciRah

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J. Hitron — researcher profile on SciRah

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N. Gao — researcher profile on SciRah