Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

R. Poon · SciRah

Researcher profile · Semantic Scholar

R. Poon

Share profile

R. Poon — researcher profile on SciRah

h-index: 39
Works: 120
Citations: 4,594

Most-cited papers

Cyclin-Dependent Kinases and S Phase Control in Mammalian Cells
Richard A. Woo, R. Poon
2003Cell Cycle242 citations Open access
Semantic Scholar
A roller coaster ride with the mitotic cyclins.
Tsz-Kan Fung, R. Poon
2005Seminars in Cell and Developmental Biology200 citations
Semantic Scholar
How Many Mutant p53 Molecules Are Needed To Inactivate a Tetramer?
W. Chan, Wai-Yi Siu, A. Lau, R. Poon
2004Molecular and Cellular Biology181 citations Open access
Semantic Scholar
Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.
Richard A. Woo, R. Poon
2004Genes & Development136 citations Open access
Semantic Scholar
The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability.
Yue Chen, R. Poon
2008Frontiers in Bioscience124 citations
Semantic Scholar
How protein kinases co-ordinate mitosis in animal cells.
Hoi-Tang Ma, R. Poon
2011Biochemical Journal122 citations
Semantic Scholar
Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.
S. Xie, O. Mortusewicz, Hoi-Tang Ma, P. Herr +3 more
2015Molecules and Cells120 citations Open access
Semantic Scholar
DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis
F. Ye, E. Kang, Chuan Yu, Xu-Yu Qian +8 more
2017Neuron119 citations Open access
Semantic Scholar
Specialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factor.
Tsz-Kan Fung, Hoi-Tang Ma, R. Poon
2007Molecular Biology of the Cell109 citations Open access
Semantic Scholar
Synchronization of HeLa Cells.
Hoi-Tang Ma, R. Poon
2017Methods in molecular biology99 citations
Semantic Scholar
Differential Contribution of Inhibitory Phosphorylation of CDC2 and CDK2 for Unperturbed Cell Cycle Control and DNA Integrity Checkpoints*
J. P. H. Chow, Wai-Yi Siu, Horace T. B. Ho, Ken-Hoi-Tang Ma +2 more
2003Journal of Biological Chemistry93 citations Open access
Semantic Scholar
Cell Cycle Control: A System of Interlinking Oscillators.
R. Poon
2016Methods in molecular biology89 citations
Semantic Scholar
Cyclin F Is Degraded during G2-M by Mechanisms Fundamentally Different from Other Cyclins*
Tsz-Kan Fung, Wai-Yi Siu, Cain H. Yam, A. Lau +1 more
2002Journal of Biological Chemistry88 citations Open access
Semantic Scholar
TRIP13 Regulates Both the Activation and Inactivation of the Spindle-Assembly Checkpoint.
Hoi-Tang Ma, R. Poon
2016Cell Reports79 citations Open access
Semantic Scholar
Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells.
R. Graeser, J. Gannon, R. Poon, T. Dubois +2 more
2002Journal of Cell Science79 citations
Semantic Scholar
p53 deficiency enhances mitotic arrest and slippage induced by pharmacological inhibition of Aurora kinases
Miriam Marxer, Hoi-Tang Ma, Wing-Yu Man, R. Poon
2014Oncogene77 citations Open access
Semantic Scholar
Ubiquitination of p53 at Multiple Sites in the DNA-Binding Domain
W. Chan, Man-Chi Mak, Tsz-Kan Fung, A. Lau +2 more
2006Molecular Cancer Research73 citations Open access
Semantic Scholar
PARP1 Is Overexpressed in Nasopharyngeal Carcinoma and Its Inhibition Enhances Radiotherapy
J. P. H. Chow, Wing-Yu Man, Mao Mao, Han Chen +5 more
2013Molecular Cancer Therapeutics72 citations Open access
Semantic Scholar
Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.
Wai-Yi Siu, A. Lau, T. Arooz, J. P. H. Chow +2 more
2004Molecular Cancer Therapeutics66 citations Open access
Semantic Scholar
Cyclin A2-Cyclin-Dependent Kinase 2 Cooperates with the PLK1-SCFβ-TrCP1-EMI1-Anaphase-Promoting Complex/Cyclosome Axis To Promote Genome Reduplication in the Absence of Mitosis
Hoi-Tang Ma, Y. Tsang, Miriam Marxer, R. Poon
2009Molecular and Cellular Biology60 citations Open access
Semantic Scholar
Differential Mode of Regulation of the Checkpoint Kinases CHK1 and CHK2 by Their Regulatory Domains*
Chuen-Pei Ng, Hung-Chiu Lee, Chung-Wai Ho, T. Arooz +3 more
2004Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Inhibitory Phosphorylation of Cyclin-Dependent Kinase 1 as a Compensatory Mechanism for Mitosis Exit
J. P. H. Chow, R. Poon, Hoi-Tang Ma
2011Molecular and Cellular Biology57 citations Open access
Semantic Scholar
DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.
J. P. H. Chow, Wai-Yi Siu, Tsz-Kan Fung, W. Chan +5 more
2003Molecular Biology of the Cell53 citations Open access
Semantic Scholar
Aurora kinases and DNA damage response.
Hoi-Tang Ma, R. Poon
2020Mutation research52 citations
Semantic Scholar
Mitotic slippage is determined by p31comet and the weakening of the spindle-assembly checkpoint
Tsun-Ming Lok, Yang Wang, Wendy Kaichun Xu, S. Xie +2 more
2020Oncogene48 citations Open access
Semantic Scholar
TRIP13 Functions in the Establishment of the Spindle Assembly Checkpoint by Replenishing O-MAD2.
Hoi-Tang Ma, R. Poon
2018Cell Reports45 citations Open access
Semantic Scholar
CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis
Y. Chan, Hoi-Tang Ma, Winnie Wong, Chui-Chui Ho +2 more
2008Cell Cycle45 citations Open access
Semantic Scholar
The N-terminal Regulatory Domain of Cyclin A Contains Redundant Ubiquitination Targeting Sequences and Acceptor Sites
Tsz-Kan Fung, Cain H. Yam, R. Poon
2005Cell Cycle45 citations Open access
Semantic Scholar
Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01
K. On, Yue Chen, Hoi-Tang Ma, J. P. H. Chow +1 more
2011Molecular Cancer Therapeutics41 citations Open access
Semantic Scholar
MASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activation
Po-Yee Wong, Hoi-Tang Ma, Hyun-Jung Lee, R. Poon
2016Scientific Reports39 citations Open access
Semantic Scholar
Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.
Chui-Chui Ho, Wai-Yi Siu, A. Lau, W. Chan +2 more
2006Cancer Research39 citations Open access
Semantic Scholar
Synergism between ATM and PARP1 Inhibition Involves DNA Damage and Abrogating the G2 DNA Damage Checkpoint
J. P. Mak, Hoi-Tang Ma, R. Poon
2019Molecular Cancer Therapeutics38 citations Open access
Semantic Scholar
Stress-activated mitogen-activated protein kinases c-Jun NH2-terminal kinase and p38 target Cdc25B for degradation.
Sanae Uchida, K. Yoshioka, R. Kizu, H. Nakagama +4 more
2009Cancer Research38 citations Open access
Semantic Scholar
Synchronization of HeLa cells.
Hoi-Tang Ma, R. Poon
2011Methods in molecular biology37 citations
Semantic Scholar
The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint.
Chui-Chui Ho, Wai-Yi Siu, J. P. H. Chow, A. Lau +4 more
2005Experimental Cell Research37 citations
Semantic Scholar
Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells
J. P. Mak, Wing-Yu Man, J. P. H. Chow, Hoi-Tang Ma +1 more
2015OncoTarget36 citations Open access
Semantic Scholar
Orderly Inactivation of the Key Checkpoint Protein Mitotic Arrest Deficient 2 (MAD2) during Mitotic Progression*
Hoi-Tang Ma, R. Poon
2011Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe
Jingjing Li, Myung Jin Hong, J. P. H. Chow, Wing-Yu Man +3 more
2015OncoTarget33 citations Open access
Semantic Scholar
Pharmacological targeting the ATR–CHK1–WEE1 axis involves balancing cell growth stimulation and apoptosis
J. P. Mak, Wing-Yu Man, Hoi-Tang Ma, R. Poon
2014OncoTarget30 citations Open access
Semantic Scholar
Depletion of p31comet Protein Promotes Sensitivity to Antimitotic Drugs*
Hoi-Tang Ma, Y. Chan, Xiao Chen, K. On +1 more
2012Journal of Biological Chemistry30 citations Open access
Semantic Scholar
An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells
Hoi-Tang Ma, K. On, Y. Tsang, R. Poon
2007Nucleic Acids Research27 citations Open access
Semantic Scholar
Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe
Y. Chan, Y. Chen, R. Poon
2009Oncogene25 citations Open access
Semantic Scholar
Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells.
Hon-Wai Lau, Hoi-Tang Ma, Tsz-Kwan Yeung, Man-Yee Tam +3 more
2021Cell Reports24 citations Open access
Semantic Scholar
The Kinetics of p53 Activation Versus Cyclin E Accumulation Underlies the Relationship between the Spindle-assembly Checkpoint and the Postmitotic Checkpoint*
Y. Chan, K. On, W. Chan, Winnie Wong +3 more
2008Journal of Biological Chemistry24 citations Open access
Semantic Scholar
SCFβTrCP mediates stress-activated MAPK-induced Cdc25B degradation
Sanae Uchida, N. Watanabe, Y. Kudo, K. Yoshioka +5 more
2011Journal of Cell Science22 citations Open access
Semantic Scholar
Inhibition of Eg5 Acts Synergistically with Checkpoint Abrogation in Promoting Mitotic Catastrophe
Yue Chen, J. P. H. Chow, R. Poon
2012Molecular Cancer Research21 citations Open access
Semantic Scholar
DNA damage and polyploidization.
J. P. H. Chow, R. Poon
2010Advances in Experimental Medicine and Biology21 citations
Semantic Scholar
Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukaemia.
N. Cheung, Chi W. So, J. Yam, Cary K. C. So +3 more
2004Biochemical Journal19 citations Open access
Semantic Scholar
The p53 Isoform Deltap53 lacks intrinsic transcriptional activity and reveals the critical role of nuclear import in dominant-negative activity.
W. Chan, R. Poon
2007Cancer Research18 citations
Semantic Scholar
Conditional gene inactivation by combining tetracycline-mediated transcriptional repression and auxin-inducible degron-mediated degradation
Lau-Yan Ng, Hoi-Tang Ma, Julio C Y Liu, Xin-Er Huang +2 more
2019Cell Cycle17 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Hoi-Tang Ma×24
Invite
Hoi-Tang Ma — researcher profile on SciRah
J. P. H. Chow×11
Invite
J. P. H. Chow — researcher profile on SciRah
Wai-Yi Siu×9
Invite
Wai-Yi Siu — researcher profile on SciRah
A. Lau×8
Invite
A. Lau — researcher profile on SciRah

×6

Invite

Tsz-Kan Fung — researcher profile on SciRah

Invite

W. Chan — researcher profile on SciRah

Invite

Wing-Yu Man — researcher profile on SciRah

Invite

T. Arooz — researcher profile on SciRah

Invite

K. On — researcher profile on SciRah

Chui-Chui Ho×4

Invite

Chui-Chui Ho — researcher profile on SciRah

Invite

J. P. Mak — researcher profile on SciRah

Invite

Yue Chen — researcher profile on SciRah