Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

T. Dalton · SciRah

Researcher profile · Semantic Scholar

T. Dalton

Share profile

T. Dalton — researcher profile on SciRah

h-index: 53
Works: 95
Citations: 13K

Most-cited papers

Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer*
D. Nebert, T. Dalton, A. Okey, F. Gonzalez
2004Journal of Biological Chemistry1,185 citations Open access
Semantic Scholar
Regulation of gene expression by reactive oxygen.
T. Dalton, H. Shertzer, A. Puga
1999Annual Review of Pharmacology and Toxicology1,159 citations
Semantic Scholar
Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis.
D. Nebert, A. Roe, Matthew Z. Dieter, W. Solis +2 more
2000Biochemical Pharmacology1,014 citations
Semantic Scholar
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
D. Nebert, T. Dalton
2006Nature Reviews. Cancer946 citations
Semantic Scholar
ZIP8, Member of the Solute-Carrier-39 (SLC39) Metal-Transporter Family: Characterization of Transporter Properties
Lei He, Kuppuswami Girijashanker, T. Dalton, Jodie M. Reed +3 more
2006Molecular Pharmacology346 citations
Semantic Scholar
Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter
Kuppuswami Girijashanker, Lei He, M. Soleimani, Jodie M. Reed +5 more
2008Molecular Pharmacology342 citations Open access
Semantic Scholar
Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.
Shigeyuki Uno, T. Dalton, Sandrine Derkenne, C. Curran +3 more
2004Molecular Pharmacology336 citations
Semantic Scholar
Aromatic Hydrocarbon Receptor Interaction with the Retinoblastoma Protein Potentiates Repression of E2F-dependent Transcription and Cell Cycle Arrest*
A. Puga, S. Barnes, T. Dalton, Ching-Yi Chang +2 more
2000Journal of Biological Chemistry327 citations Open access
Semantic Scholar
Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway
J. Maher, Matthew Z. Dieter, L. Aleksunes, Angela L. Slitt +9 more
2007Hepatology322 citations Open access
Semantic Scholar
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis.
T. Dalton, Lei He, Bin Wang, Marian L. Miller +5 more
2005Proceedings of the National Academy of Sciences of the United States of America298 citations Open access
Semantic Scholar
Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3*
Ling Gao, Jia-Kun Wang, K. Sekhar, Huiyong Yin +8 more
2007Journal of Biological Chemistry292 citations Open access
Semantic Scholar
Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde.
A. Senft, T. Dalton, H. Shertzer
2000Analytical Biochemistry292 citations
Semantic Scholar
Genetically altered mice to evaluate glutathione homeostasis in health and disease.
T. Dalton, Ying Chen, Scott N. Schneider, D. Nebert +1 more
2004Free Radical Biology & Medicine286 citations
Semantic Scholar
Initial Characterization of the Glutamate-Cysteine Ligase Modifier Subunit Gclm(−/−) Knockout Mouse
Yi Yang, Matthew Z. Dieter, Ying Chen, H. Shertzer +2 more
2002Journal of Biological Chemistry271 citations Open access
Semantic Scholar
Oxidative Stress Activates Metal-responsive Transcription Factor-1 Binding Activity
T. Dalton, Qing X. Li, D. Bittel, Luchuan Liang +1 more
1996Journal of Biological Chemistry242 citations Open access
Semantic Scholar
Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.
T. Dalton, Matthew Z. Dieter, Yi Yang, H. Shertzer +1 more
2000Biochemical and Biophysical Research Communications - BBRC237 citations
Semantic Scholar
Oral Benzo[a]pyrene in Cyp1 Knockout Mouse Lines: CYP1A1 Important in Detoxication, CYP1B1 Metabolism Required for Immune Damage Independent of Total-Body Burden and Clearance Rate
Shigeyuki Uno, T. Dalton, Nadine Dragin, C. Curran +5 more
2006Molecular Pharmacology235 citations
Semantic Scholar
Redox Dysregulation Affects the Ventral But Not Dorsal Hippocampus: Impairment of Parvalbumin Neurons, Gamma Oscillations, and Related Behaviors
P. Steullet, J. Cabungcal, Anita Kulak, R. Kraftsik +4 more
2010Journal of Neuroscience207 citations Open access
Semantic Scholar
Induction of cellular oxidative stress by aryl hydrocarbon receptor activation.
T. Dalton, A. Puga, H. Shertzer
2002Chemico-Biological Interactions181 citations
Semantic Scholar
Dioxin causes a sustained oxidative stress response in the mouse.
H. Shertzer, D. Nebert, A. Puga, Michelle Ary +5 more
1998Biochemical and Biophysical Research Communications - BBRC166 citations
Semantic Scholar
Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.
A. Senft, T. Dalton, D. Nebert, Mary Beth Genter +5 more
2002Free Radical Biology & Medicine157 citations
Semantic Scholar
Cd2+ versus Zn2+ uptake by the ZIP8 HCO3--dependent symporter: kinetics, electrogenicity and trafficking.
Zhiwei Liu, Hong C. Li, M. Soleimani, Kuppuswami Girijashanker +4 more
2008Biochemical and Biophysical Research Communications - BBRC151 citations Open access
Semantic Scholar
Glutathione Redox State Regulates Mitochondrial Reactive Oxygen Production*
Dongxiao Shen, T. Dalton, D. Nebert, H. Shertzer
2005Journal of Biological Chemistry149 citations Open access
Semantic Scholar
Hepatocyte‐specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure
Ying Chen, Yi Yang, Marian L. Miller, Dongxiao Shen +6 more
2007Hepatology142 citations Open access
Semantic Scholar
Glutamate Cysteine Ligase Catalysis
Ying Chen, H. Shertzer, Scott N. Schneider, D. Nebert +1 more
2005Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Dioxin exposure is an environmental risk factor for ischemic heart disease
T. Dalton, J. Kerzee, Bin Wang, Marian L. Miller +5 more
2007Cardiovascular Toxicology127 citations
Semantic Scholar
Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.
Shigeyuki Uno, T. Dalton, P. Sinclair, N. Gorman +5 more
2004Toxicology and Applied Pharmacology125 citations
Semantic Scholar
Dioxin increases reactive oxygen production in mouse liver mitochondria.
A. Senft, T. Dalton, D. Nebert, M. Genter +2 more
2002Toxicology and Applied Pharmacology124 citations
Semantic Scholar
Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.
T. Dalton, Matthew Z. Dieter, Robin S. Matlib, Nicole L. Childs +3 more
2000Biochemical and Biophysical Research Communications - BBRC118 citations
Semantic Scholar
Transgenic Zebrafish as Sentinels for Aquatic Pollution
M. Carvan, T. Dalton, G. Stuart, D. Nebert
2000Annals of the New York Academy of Sciences116 citations
Semantic Scholar
Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.
Bin Wang, Scott N. Schneider, Nadine Dragin, Kuppuswami Girijashanker +7 more
2007American Journal of Physiology - Cell Physiology113 citations
Semantic Scholar
Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels.
Shigeyuki Uno, T. Dalton, H. Shertzer, Mary Beth Genter +3 more
2001Biochemical and Biophysical Research Communications - BBRC113 citations
Semantic Scholar
Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress.
W. Solis, T. Dalton, Matthew Z. Dieter, S. Freshwater +4 more
2002Biochemical Pharmacology111 citations
Semantic Scholar
Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit
S. Lavoie, Ying Chen, T. Dalton, R. Gysin +3 more
2009Journal of Neurochemistry109 citations
Semantic Scholar
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.
C. Cheung, Xiaochao Ma, K. Krausz, S. Kimura +5 more
2005Chemical Research in Toxicology102 citations
Semantic Scholar
Isolation and sequence of cDNA clones encoding rat phosphatidylinositol transfer protein.
S. Dickeson, C. Lim, G. T. Schuyler, T. Dalton +2 more
1989Journal of Biological Chemistry95 citations
Semantic Scholar
Protection of the Cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Andrew G. Smith, B. Clothier, Philip Carthew, Nicole L. Childs +3 more
2001Toxicology and Applied Pharmacology92 citations
Semantic Scholar
TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F(0)F(1)-ATP synthase and ubiquinone.
H. Shertzer, M. Genter, Dongxiao Shen, D. Nebert +2 more
2006Toxicology and Applied Pharmacology90 citations Open access
Semantic Scholar
Temporalspatial patterns of expression of metallothionein-I and -III and other stress related genes in rat brain after kainic acid-induced seizures.
T. Dalton, T. Pazdernik, J. Wagner, F. Samson +1 more
1995Neurochemistry International84 citations
Semantic Scholar
Toward the evaluation of function in genetic variability: Characterizing human SNP frequencies and establishing BAC‐transgenic mice carrying the human CYP1A1_CYP1A2 locus
Zheng-Wen Jiang, T. Dalton, Li Jin, Bin Wang +4 more
2005Human Mutation82 citations Open access
Semantic Scholar
Uroporphyria produced in mice by iron and 5-aminolaevulinic acid does not occur in Cyp1a2(-/-) null mutant mice.
P. Sinclair, N. Gorman, T. Dalton, Heidi S. Walton +4 more
1998Biochemical Journal81 citations Open access
Semantic Scholar
4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice.
Y. Tsuneoka, T. Dalton, Marian L. Miller, C. Clay +4 more
2003Journal of the National Cancer Institute74 citations
Semantic Scholar
Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.
Shigeyuki Uno, Nadine Dragin, Marian L. Miller, T. Dalton +2 more
2008Free Radical Biology & Medicine72 citations Open access
Semantic Scholar
Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line.
Nadine Dragin, Shigeyuki Uno, Bin Wang, T. Dalton +1 more
2007Biochemical and Biophysical Research Communications - BBRC69 citations Open access
Semantic Scholar
Disruption of dioxin‐inducible phase I and phase II gene expression patterns by cadmium, chromium, and arsenic
A. Maier, T. Dalton, A. Puga
2000Molecular Carcinogenesis68 citations
Semantic Scholar
CYP1A2 is essential in murine uroporphyria caused by hexachlorobenzene and iron.
Peter R. Sinclair, N. Gorman, Heidi S. Walton, W. Bement +4 more
2000Toxicology and Applied Pharmacology62 citations Open access
Semantic Scholar
Uncoupling-mediated generation of reactive oxygen by halogenated aromatic hydrocarbons in mouse liver microsomes.
H. Shertzer, C. Clay, M. Genter, Mark C. Chames +4 more
2004Free Radical Biology & Medicine60 citations
Semantic Scholar
Characterization of the MTF-1 transcription factor from zebrafish and trout cells.
T. Dalton, Willy A. Solis, D. Nebert, M. Carvan
2000Comparative Biochemistry and Physiology Part B Comparative Biochemistry60 citations
Semantic Scholar
Dose-response: an International Journal Induction of Oxidative Stress Responses by Dioxin and Other Ligands of the Aryl Hydrocarbon Receptor Recommended Citation Induction of Oxidative Stress Responses by Dioxin and Other Ligands of the Aryl Hydrocarbon Receptor
J. Reichard, T. Dalton, H. Shertzer, A. Puga
59 citations
Semantic Scholar
Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones.
H. Shertzer, Alvaro Puga, Ching-Yi Chang, Paul W. Smith +3 more
1999Chemico-Biological Interactions58 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

D. Nebert×37
Invite
D. Nebert — researcher profile on SciRah
H. Shertzer×25
Invite
H. Shertzer — researcher profile on SciRah
Marian L. Miller×9
Invite
Marian L. Miller — researcher profile on SciRah
A. Puga×8
Invite
A. Puga — researcher profile on SciRah

×8

Invite

Bin Wang — researcher profile on SciRah

Invite

Ying Chen — researcher profile on SciRah

Shigeyuki Uno×7

Invite

Shigeyuki Uno — researcher profile on SciRah

Matthew Z. Dieter×6

Invite

Matthew Z. Dieter — researcher profile on SciRah

Scott N. Schneider×6

Invite

Scott N. Schneider — researcher profile on SciRah

Invite

Lei He — researcher profile on SciRah

Invite

F. Gonzalez — researcher profile on SciRah

Invite

Yi Yang — researcher profile on SciRah