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D. A. Rodrigues · SciRah

Researcher profile · Semantic Scholar

D. A. Rodrigues

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D. A. Rodrigues — researcher profile on SciRah

h-index: 14
Works: 26
Citations: 1,111

Most-cited papers

Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?
Sreekanth Thota, D. A. Rodrigues, D. Crans, E. Barreiro
2018Journal of Medicinal Chemistry393 citations
Semantic Scholar
N-Acylhydrazones as drugs.
Sreekanth Thota, D. A. Rodrigues, Pedro de Sena Murteira Pinheiro, L. M. Lima +2 more
2018Bioorganic & Medicinal Chemistry Letters187 citations Open access
Semantic Scholar
Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors.
D. A. Rodrigues, Guilherme A. Ferreira-Silva, Ana C. S. Ferreira, R. A. Fernandes +4 more
2016Journal of Medicinal Chemistry95 citations Open access
Semantic Scholar
Duvelisib: A 2018 Novel FDA-Approved Small Molecule Inhibiting Phosphoinositide 3-Kinases
D. A. Rodrigues, F. S. Sagrillo, C. A. M. Fraga
2019Pharmaceuticals71 citations Open access
Semantic Scholar
The Use of Conformational Restriction in Medicinal Chemistry.
Pedro de Sena M Pinheiro, D. A. Rodrigues, Rodolfo Do Couto Maia, Sreekanth Thota +1 more
2019Current Topics in Medicinal Chemistry57 citations
Semantic Scholar
Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities
D. A. Rodrigues, Pedro de S. M. Pinheiro, F. S. Sagrillo, M. Bolognesi +1 more
2020Medicinal research reviews (Print)48 citations
Semantic Scholar
Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors
D. A. Rodrigues, F. Guerra, F. S. Sagrillo, Pedro S. M. Pinheiro +6 more
2020ChemMedChem38 citations
Semantic Scholar
The path to venetoclax resistance is paved with mutations, metabolism, and more
Graeme P. Sullivan, Lyndsey Flanagan, D. A. Rodrigues, Tríona Ní Chonghaile
2022Science Translational Medicine36 citations
Semantic Scholar
Synthesis, characterization, DNA binding, DNA cleavage, protein binding and cytotoxic activities of Ru(II) complexes.
Sreekanth Thota, Srujana Vallala, Rajeshwar Yerra, D. A. Rodrigues +2 more
2016International Journal of Biological Macromolecules35 citations Open access
Semantic Scholar
Beyond the Selective Inhibition of Histone Deacetylase 6.
D. A. Rodrigues, Sreekanth Thota, C. A. M. Fraga
2016Mini-Reviews in Medical Chemistry21 citations
Semantic Scholar
Advances in the Design and Development of PROTAC-mediated HDAC degradation.
D. A. Rodrigues, A. Roe, D. Griffith, T. Chonghaile
2021Current Topics in Medicinal Chemistry19 citations Open access
Semantic Scholar
Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and Future Prospects
D. A. Rodrigues, Pedro S. M. Pinheiro, C. A. M. Fraga
2020ChemMedChem19 citations
Semantic Scholar
An Unusual Intramolecular Halogen Bond Guides Conformational Selection.
R. Tesch, C. Becker, M. Müller, M. E. Beck +13 more
2018Angewandte Chemie15 citations
Semantic Scholar
Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.
Tatiana F. Gomes, Thais E. T. Pompeu, D. A. Rodrigues, F. Noël +11 more
2013European journal of medicinal chemistry15 citations Open access
Semantic Scholar
Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40)
D. A. Rodrigues, Pedro de Sena Murteira Pinheiro, Thayssa Tavares da Silva Cunha Ferreira, Sreekanth Thota +1 more
2018Chemical Biology and Drug Design13 citations
Semantic Scholar
Theoretical and experimental characterization of 1,4-N⋯S σ-hole intramolecular interactions in bioactive N-acylhydrazone derivatives
Pedro de Sena Murteira Pinheiro, D. A. Rodrigues, M. A. Alves, L. Tinoco +3 more
201812 citations
Semantic Scholar
Novel Single Inhibitor of HDAC6/8 and Dual Inhibitor of PI3K/HDAC6 as Potential Alternative Treatments for Prostate Cancer
F. Guerra, D. A. Rodrigues, C. A. M. Fraga, P. Fernandes
2021Pharmaceuticals11 citations Open access
Semantic Scholar
Recent Advances in Development of Polyphenols as Anticancer Agents.
Sreekanth Thota, D. A. Rodrigues, E. Barreiro
2018Mini-Reviews in Medical Chemistry11 citations
Semantic Scholar
Modeling zinc-oxygen coordination in histone deacetylase: A comparison of semiempirical methods performance
Pedro de Sena Murteira Pinheiro, D. A. Rodrigues, C. Sant'anna, C. A. Fraga
2018International Journal of Quantum Chemistry8 citations
Semantic Scholar
Structure–property relationship studies of 3-acyl-substituted furans: the serendipitous identification and characterization of a new non-classical hydrogen bond donor moiety
D. A. Rodrigues, Pedro de Sena M. Pinheiro, Fernanda S. Sagrillo, M. Freitas +6 more
2020New Journal of Chemistry4 citations
Semantic Scholar
Recent Advances in the Use of Multitarget Therapeutics.
D. A. Rodrigues
2022Current Topics in Medicinal Chemistry3 citations
Semantic Scholar
Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases
Thayssa Tavares da Silva Cunha, R. Silva, D. A. Rodrigues, Pedro de Sena Murteira Pinheiro +4 more
2022Biomolecules2 citations Open access
Semantic Scholar
Numerical Simulation of High-Concentration Slurry Flow in Squared T-Junctions
E. David, D. A. Rodrigues, A. P. Silva Freire
2023Proceeding of 10th International Symposium on Turbulence, Heat and Mass Transfer, THMT-23, Rome, Italy, 11-15 September 20230 citations
Semantic Scholar
Eine ungewöhnliche intramolekulare Halogenbindung führt zu konformationeller Selektion
Roberta Tesch, C. Becker, M. Müller, M. Beck +13 more
2018Angewandte Chemie0 citations
Semantic Scholar
CCDC 1848022: Experimental Crystal Structure Determination
R. Tesch, C. Becker, M. Müller, M. E. Beck +13 more
20180 citations
Semantic Scholar
Design, synthesis, structural characterization and in vitro cytotoxic activity of mononuclear Ru(II)complexes
Sreekanth Thota, Srujana Vallala, Rajeshwar Yerra, D. A. Rodrigues +1 more
2016Medicinal Chemistry Research0 citations
Semantic Scholar

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Sreekanth Thota×10
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Sreekanth Thota — researcher profile on SciRah
C. A. M. Fraga×10
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C. A. M. Fraga — researcher profile on SciRah
C. Sant'anna×9
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Pedro de Sena Murteira Pinheiro×8
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F. S. Sagrillo×3

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