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E. M. Kennedy · SciRah

Researcher profile · Semantic Scholar

E. M. Kennedy

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E. M. Kennedy — researcher profile on SciRah

h-index: 32
Works: 58
Citations: 3,910

Most-cited papers

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection
Nandan S. Gokhale, Alexa B. R. McIntyre, M. J. McFadden, A. Roder +15 more
2016Cell Host and Microbe437 citations Open access
Semantic Scholar
Post-transcriptional m6A editing of HIV-1 mRNAs enhances viral gene expression
E. M. Kennedy, H. Bogerd, A. Kornepati, Dong Kang +7 more
2016Cell Host and Microbe339 citations Open access
Semantic Scholar
Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications
Ari E. Friedland, Reshica Baral, Pankhuri Singhal, Katherine Loveluck +12 more
2015Genome Biology273 citations Open access
Semantic Scholar
Inactivation of the Human Papillomavirus E6 or E7 Gene in Cervical Carcinoma Cells by Using a Bacterial CRISPR/Cas RNA-Guided Endonuclease
E. M. Kennedy, A. Kornepati, Michael Goldstein, H. Bogerd +4 more
2014Journal of Virology273 citations Open access
Semantic Scholar
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease
E. M. Kennedy, L. Bassit, Henrik Mueller, A. Kornepati +6 more
2014Virology226 citations Open access
Semantic Scholar
Epitranscriptomic enhancement of influenza A virus gene expression and replication
D. Courtney, E. M. Kennedy, Rebekah E. Dumm, H. Bogerd +3 more
2017Cell Host and Microbe209 citations Open access
Semantic Scholar
Epitranscriptomic addition of m5C to HIV-1 transcripts regulates viral gene expression
D. Courtney, K. Tsai, H. Bogerd, E. M. Kennedy +5 more
2019Cell Host and Microbe173 citations Open access
Semantic Scholar
Replication of Many Human Viruses Is Refractory to Inhibition by Endogenous Cellular MicroRNAs
H. Bogerd, Rebecca L. Skalsky, E. M. Kennedy, Y. Furuse +10 more
2014Journal of Virology142 citations Open access
Semantic Scholar
A CRISPR activation screen identifies a pan-avian influenza virus inhibitory host factor
Brook E. Heaton, E. M. Kennedy, Rebekah E. Dumm, Alfred T. Harding +3 more
2017Cell Reports136 citations Open access
Semantic Scholar
Differential RISC association of endogenous human microRNAs predicts their inhibitory potential
O. Flores, E. M. Kennedy, Rebecca L. Skalsky, B. Cullen
2014Nucleic Acids Research122 citations Open access
Semantic Scholar
Derivation and characterization of Dicer- and microRNA-deficient human cells
H. Bogerd, Adam W. Whisnant, E. M. Kennedy, O. Flores +1 more
2014RNA: A publication of the RNA Society116 citations Open access
Semantic Scholar
Human epistatic interaction controls IL7R splicing and increases Multiple Sclerosis risk
Gaddiel Galarza-Muñoz, Farren B. S. Briggs, Irina Y Evsyukova, Geraldine Schott-Lerner +11 more
2017Cell105 citations Open access
Semantic Scholar
Ribonucleoside Triphosphates as Substrate of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Human Macrophages
E. M. Kennedy, C. Gavegnano, L. Nguyen, R. Slater +4 more
2010Journal of Biological Chemistry102 citations Open access
Semantic Scholar
Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression
E. M. Kennedy, H. Bogerd, A. Kornepati, Dong Kang +7 more
2017Cell Host and Microbe91 citations Open access
Semantic Scholar
SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells
Serena Bonifati, M. B. Daly, C. StGelais, S. H. Kim +7 more
2016Virology90 citations Open access
Semantic Scholar
Targeting hepatitis B virus cccDNA using CRISPR/Cas9.
E. M. Kennedy, A. Kornepati, B. Cullen
2015Antiviral Research87 citations
Semantic Scholar
Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer
E. M. Kennedy, Adam W. Whisnant, A. Kornepati, Joy B. Marshall +2 more
2015Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
Functional analysis of NsrR, a nitric oxide sensing Rrf2 repressor in Neisseria gonorrhoeae
Vincent M. Isabella, John D. Lapek, E. M. Kennedy, V. Clark
2009Molecular Microbiology75 citations Open access
Semantic Scholar
Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment
E. M. Kennedy, B. Cullen
2015Virology66 citations Open access
Semantic Scholar
Viral Epitranscriptomics
E. M. Kennedy, D. Courtney, K. Tsai, B. Cullen
2017Journal of Virology65 citations Open access
Semantic Scholar
Expression of CRISPR/Cas single guide RNAs using small tRNA promoters
Adam L Mefferd, A. Kornepati, H. Bogerd, E. M. Kennedy +1 more
2015RNA: A publication of the RNA Society65 citations Open access
Semantic Scholar
Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression
D. Courtney, Andrea Chalem, H. Bogerd, Brittany A. Law +3 more
2019mBio64 citations Open access
Semantic Scholar
ONCR-177, an Oncolytic HSV-1 Designed to Potently Activate Systemic Antitumor Immunity
B. Haines, A. Denslow, Peter Grzesik, Jennifer S. Lee +15 more
2020Cancer immunology research63 citations
Semantic Scholar
Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators
H. Bogerd, A. Kornepati, Joy B. Marshall, E. M. Kennedy +1 more
2015Proceedings of the National Academy of Sciences of the United States of America57 citations Open access
Semantic Scholar
Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing
K. Tsai, H. Bogerd, E. M. Kennedy, A. Emery +2 more
2021bioRxiv56 citations Open access
Semantic Scholar
Frequent Incorporation of Ribonucleotides during HIV-1 Reverse Transcription and Their Attenuated Repair in Macrophages*
E. M. Kennedy, Sarah M. Amie, R. Bambara, Baek Kim
2012Journal of Biological Chemistry48 citations Open access
Semantic Scholar
The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents
C. Gavegnano, E. M. Kennedy, Baek Kim, R. Schinazi
2012Molecular Biology International44 citations Open access
Semantic Scholar
Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer
E. M. Kennedy, A. Denslow, J. Hewett, Ling-Xin Kong +21 more
2021Nature Communications40 citations Open access
Semantic Scholar
Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication
K. Tsai, D. Courtney, E. M. Kennedy, B. Cullen
2018RNA: A publication of the RNA Society34 citations Open access
Semantic Scholar
Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo
David S. Hsu, A. Kornepati, Wayne J. Glover, E. M. Kennedy +1 more
2018Future Virology34 citations Open access
Semantic Scholar
Gene Editing: A New Tool for Viral Disease.
E. M. Kennedy, B. Cullen
2017Annual Review of Medicine34 citations
Semantic Scholar
Abundant Non-canonical dUTP Found in Primary Human Macrophages Drives Its Frequent Incorporation by HIV-1 Reverse Transcriptase*
E. M. Kennedy, Waaqo Daddacha, R. Slater, C. Gavegnano +3 more
2011Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability
E. M. Kennedy, Terry Farkaly, Peter Grzesik, Jennifer S. Lee +15 more
2020Molecular Therapy: Oncolytics24 citations Open access
Semantic Scholar
Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic
E. M. Kennedy, A. Kornepati, Adam L Mefferd, Joy B. Marshall +3 more
2015Methods20 citations Open access
Semantic Scholar
A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs
B. Poling, K. Tsai, Dong Kang, Linda Ren +2 more
2017RNA Biology16 citations Open access
Semantic Scholar
Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity
H. Bogerd, E. M. Kennedy, Adam W. Whisnant, B. Cullen
2017mBio16 citations Open access
Semantic Scholar
The Mechanistic Architecture of the Thermostable Pyrococcus Furiosus Family B DNA Polymerase Motif A and its Interaction with dNTP Substrate
E. M. Kennedy, C. Hergott, S. Dewhurst, Baek Kim
2009Biochemistry16 citations Open access
Semantic Scholar
The impact of molecular manipulation in residue 114 of Human Immunodeficiency Virus Type-1 reverse transcriptase on dNTP substrate binding and viral replication
Sarah K. Van Cor-Hosmer, Waaqo Daddacha, Z. Kelly, Amy Tsurumi +2 more
2011Virology14 citations Open access
Semantic Scholar
Effect of Ribonucleotides Embedded in a DNA Template on HIV-1 Reverse Transcription Kinetics and Fidelity*
Waaqo Daddacha, E. Noble, L. Nguyen, E. M. Kennedy +1 more
2013Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Partial reconstitution of the RNAi response in human cells using Drosophila gene products
E. M. Kennedy, A. Kornepati, H. Bogerd, B. Cullen
2017RNA: A publication of the RNA Society6 citations Open access
Semantic Scholar
Abstract 1455: Design of ONCR-177 base vector, a next generation oncolytic herpes simplex virus type-1, optimized for robust oncolysis, transgene expression and tumor-selective replication
E. M. Kennedy, Terry Farkaly, P. Behera, Allison M. Colthart +14 more
2019Immunology4 citations
Semantic Scholar
Pre-steady State Kinetic Analysis of HIV-1 Reverse Transcriptase for Non-canonical Ribonucleoside Triphosphate Incorporation and DNA Synthesis from Ribonucleoside-containing DNA Template
L. Nguyen, Robert A. Domaoal, E. M. Kennedy, Dong-Hyun Kim +2 more
2014Antiviral Research4 citations Open access
Semantic Scholar
Seneca Valley virus replicons are packaged in trans and have the capacity to overcome the limitations of viral transgene expression
Jeffrey D. Bryant, Jennifer S. Lee, Ana Helena de Almeida, Judy Jacques +5 more
2023Molecular Therapy: Oncolytics3 citations Open access
Semantic Scholar
Epitranscriptomic Regulation of HIV-1 Gene Expression by m 5C and the Novel m 5C Reader MBD2
D. Courtney, K. Tsai, H. Bogerd, E. M. Kennedy +5 more
2019Social Science Research Network2 citations Open access
Semantic Scholar
Abstract 4773: Development of ONCR-NEP, a lipid nanoparticle delivered oncolytic virus capable of robust in situ amplification resulting in tumor lysis and regression
E. M. Kennedy, Jennifer S. Lee, Judy Jacques, Terry Farkaly +9 more
2019Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Overexpression of recombinant domain III envelope protein of Zika virus
S. Andrew, E. M. Kennedy, M. S. H. Sum
20181 citations Open access
Semantic Scholar
Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health,
H. Bogerd, Rebecca L. Skalsky, E. M. Kennedy, Y. Furuse +10 more
20141 citations
Semantic Scholar
Abstract B74: Dual mechanism of ONCR-177 enhances antitumor immunogenicity
Melissa W. Hayes, Agnieska Denslow, Jacqueline Gurshaw, Daniel M. Wambua +12 more
20200 citations
Semantic Scholar
Abstract B23: microRNA attenuated oHSV-1 armed with multiple immunomodulatory payloads mediates robust and selective antitumor immune response in preclinical tumor models
L. Lerner, E. M. Kennedy, Terry Farkaly, Allison M. Colthart +18 more
2020Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract 4572: mONCR-177 oncolytic virotherapy stimulates anti-tumor and anti-viral immunogenicity
Melissa W. Hayes, A. Denslow, J. Hewett, Daniel M. Wambua +10 more
2020Immunology0 citations
Semantic Scholar

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A. Kornepati×12
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