G. Hunninghake

Most-cited papers

Respiratory Epithelial Cells Convert Inactive Vitamin D to its Active Form
Sif Hansdóttir, M. Monick, Sara L. Hinde, Nina Lovan +2 more
2008Journal of Immunology622 citations Open access
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Acute exacerbations of idiopathic pulmonary fibrosis.
H. Collard, B. Moore, K. Flaherty, K. Brown +26 more
2007American Journal of Respiratory and Critical Care Medicine564 citations Open access
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A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis
D. Zisman, M. Schwarz, K. Anstrom, H. Collard +2 more
2010New England Journal of Medicine559 citations Open access
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Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse.
Susan V. Szapiel, Norton A. Elson, J. D. Fulmer, G. Hunninghake +1 more
2015American Review of Respiratory Disease488 citations
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Vitamin D Decreases RSV Induction of NF-κB-linked Chemokines and Cytokines in Airway Epithelium While Maintaining the Antiviral State
Sif Hansdóttir, M. Monick, Nina Lovan, Linda S. Powers +2 more
2009Journal of Immunology344 citations Open access
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Radiologic findings are strongly associated with a pathologic diagnosis of usual interstitial pneumonia.
G. Hunninghake, D. Lynch, J. Galvin, B. H. Gross +8 more
2003Chest321 citations
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Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin*
M. Monick, T. Yarovinsky, Linda S. Powers, N. Butler +3 more
2003Journal of Biological Chemistry308 citations Open access
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Cigarette smoke induces cellular senescence.
Toru Nyunoya, M. Monick, A. Klingelhutz, T. Yarovinsky +2 more
2006American Journal of Respiratory Cell and Molecular Biology295 citations Open access
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Identification of an Autophagy Defect in Smokers’ Alveolar Macrophages
M. Monick, Linda S. Powers, K. Walters, Nina Lovan +4 more
2010Journal of Immunology251 citations Open access
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Characterization of the inflammatory and immune effector cells in the lung parenchyma of patients with interstitial lung disease.
G. Hunninghake, O. Kawanami, V. Ferrans, R. C. Young +2 more
2015American Review of Respiratory Disease216 citations
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Important roles for macrophage colony-stimulating factor, CC chemokine ligand 2, and mononuclear phagocytes in the pathogenesis of pulmonary fibrosis.
Christopher P. Baran, J. Opalek, S. McMaken, C. Newland +8 more
2007American Journal of Respiratory and Critical Care Medicine195 citations Open access
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Respiratory Syncytial Virus Induces TLR3 Protein and Protein Kinase R, Leading to Increased Double-Stranded RNA Responsiveness in Airway Epithelial Cells1
Dayna J. Groskreutz, M. Monick, Linda S. Powers, T. Yarovinsky +2 more
2006Journal of Immunology166 citations Open access
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Localization of the immune response in sarcoidosis.
G. Hunninghake, J. D. Fulmer, R. C. Young, J. Gadek +1 more
2015American Review of Respiratory Disease158 citations
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Role of interleukin-2 release by lung T-cells in active pulmonary sarcoidosis.
G. Hunninghake, G. Bedell, Donald C. Zavala, M. Monick +1 more
2015American Review of Respiratory Disease138 citations
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Specific inhibition of type I interferon signal transduction by respiratory syncytial virus.
Murali Ramaswamy, Lei Shi, M. Monick, G. Hunninghake +1 more
2004American Journal of Respiratory Cell and Molecular Biology132 citations
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Noninfectious Lung Pathology in Patients With Crohn's Disease
M. Casey, H. Tazelaar, J. Myers, G. Hunninghake +4 more
2003American Journal of Surgical Pathology120 citations
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Constitutive ERK MAPK Activity Regulates Macrophage ATP Production and Mitochondrial Integrity1
M. Monick, Linda S. Powers, Christopher W. Barrett, Sara L. Hinde +6 more
2008Journal of Immunology115 citations Open access
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Activation of the Epidermal Growth Factor Receptor by Respiratory Syncytial Virus Results in Increased Inflammation and Delayed Apoptosis*
M. Monick, K. Cameron, Janice M. Staber, Linda S. Powers +3 more
2005Journal of Biological Chemistry111 citations Open access
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Anti-inflammatory response is associated with mortality and severity of infection in sepsis.
A. Ashare, Linda S. Powers, N. Butler, K. Doerschug +2 more
2005American Journal of Physiology - Lung cellular and Molecular Physiology103 citations
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Antioxidant therapy for idiopathic pulmonary fibrosis.
G. Hunninghake
2005New England Journal of Medicine102 citations
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Hereditary emphysema in the tight-skin mouse. Evaluation of pathogenesis.
Giovanni A. Rossi, G. Hunninghake, J. Gadek, Susan V. Szapiel +3 more
2015American Review of Respiratory Disease85 citations
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Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.
Toru Nyunoya, M. Monick, Aloysius L Klingelhutz, H. Glaser +7 more
2009American Journal of Respiratory and Critical Care Medicine84 citations Open access
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Sphingosine kinase mediates activation of extracellular signal-related kinase and Akt by respiratory syncytial virus.
M. Monick, K. Cameron, Linda S. Powers, N. Butler +3 more
2004American Journal of Respiratory Cell and Molecular Biology84 citations
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Transcriptional Induction of the Pseudomonas aeruginosa Type III Secretion System by Low Ca2+ and Host Cell Contact Proceeds through Two Distinct Signaling Pathways
N. Dasgupta, A. Ashare, G. Hunninghake, T. Yahr
2006Infection and Immunity79 citations
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Human alveolar macrophages suppress interleukin-1 (IL-1) activity via the secretion of prostaglandin E2.
M. Monick, John Glazier, G. Hunninghake
2015American Review of Respiratory Disease72 citations
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High levels of catalase and glutathione peroxidase activity dampen H2O2 signaling in human alveolar macrophages.
A. B. Carter, L. Tephly, S. Venkataraman, L. Oberley +4 more
2004American Journal of Respiratory Cell and Molecular Biology72 citations Open access
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Regulation of the release of alveolar macrophage-derived neutrophil chemotactic factor.
J. Gadek, G. Hunninghake, R. L. Zimmerman, R. G. Crystal
2015American Review of Respiratory Disease71 citations
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Insulin-like growth factor-1 levels contribute to the development of bacterial translocation in sepsis.
G. Hunninghake, K. Doerschug, Amanda B. Nymon, G. Schmidt +2 more
2010American Journal of Respiratory and Critical Care Medicine61 citations Open access
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Active ERK Contributes to Protein Translation by Preventing JNK-Dependent Inhibition of Protein Phosphatase 11
M. Monick, Linda S. Powers, T. Gross, D. M. Flaherty +2 more
2006Journal of Immunology61 citations Open access
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Effect of intermittent high dose parenteral corticosteroids on the alveolitis of idiopathic pulmonary fibrosis.
B. A. Keogh, John Bernardo, G. Hunninghake, B. Line +2 more
2015American Review of Respiratory Disease60 citations
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Early Exposure to IL-4 Stabilizes IL-4 mRNA in CD4+ T Cells via RNA-Binding Protein HuR1
T. Yarovinsky, N. Butler, M. Monick, G. Hunninghake
2006Journal of Immunology60 citations Open access
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Inhibition of Rho Family GTPases Results in Increased TNF-α Production After Lipopolysaccharide Exposure 1
M. Monick, Linda S. Powers, N. Butler, G. Hunninghake
2003Journal of Immunology59 citations Open access
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Cigarette smoke alters respiratory syncytial virus-induced apoptosis and replication.
Dayna J. Groskreutz, M. Monick, E. Babor, Toru Nyunoya +3 more
2009American Journal of Respiratory Cell and Molecular Biology58 citations Open access
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Cooperative Prosurvival Activity by ERK and Akt in Human Alveolar Macrophages is Dependent on High Levels of Acid Ceramidase Activity1
M. Monick, R. Mallampalli, Mary A. Bradford, Diann M. McCoy +7 more
2004Journal of Immunology55 citations Open access
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Chronic Liver Disease Impairs Bacterial Clearance in a Human Model of Induced Bacteremia
A. Ashare, C. Stanford, P. Hancock, D. Stark +5 more
2009Clinical and Translational Science52 citations Open access
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Respiratory Syncytial Virus Limits α Subunit of Eukaryotic Translation Initiation Factor 2 (eIF2α) Phosphorylation to Maintain Translation and Viral Replication*
Dayna J. Groskreutz, E. Babor, M. Monick, S. Varga +1 more
2010Journal of Biological Chemistry51 citations Open access
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Respiratory Syncytial Virus Decreases p53 Protein to Prolong Survival of Airway Epithelial Cells1
Dayna J. Groskreutz, M. Monick, T. Yarovinsky, Linda S. Powers +4 more
2007Journal of Immunology49 citations Open access
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Immune interferon is a growth factor for human lung fibroblasts.
G. Hunninghake, Christine Hemken, M. Brady, M. Monick
2015American Review of Respiratory Disease46 citations
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Severe bacteremia results in a loss of hepatic bacterial clearance.
A. Ashare, M. Monick, Linda S. Powers, T. Yarovinsky +1 more
2006American Journal of Respiratory and Critical Care Medicine46 citations Open access
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Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance.
A. Ashare, Amanda B. Nymon, K. Doerschug, J. Morrison +2 more
2008American Journal of Respiratory and Critical Care Medicine44 citations Open access
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Respiratory Syncytial Virus Synergizes with Th2 Cytokines to Induce Optimal Levels of TARC/CCL171
M. Monick, Linda S. Powers, Ihab H. Hassan, Dayna J. Groskreutz +6 more
2007Journal of Immunology39 citations Open access
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Macrophages Survive Hyperoxia via Prolonged ERK Activation Due to Phosphatase Down-regulation*
Toru Nyunoya, M. Monick, Linda S. Powers, T. Yarovinsky +1 more
2005Journal of Biological Chemistry39 citations Open access
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Antibiotics delay but do not prevent bacteremia and lung injury in murine sepsis
K. Doerschug, Linda S. Powers, M. Monick, P. Thorne +1 more
2004Critical Care Medicine39 citations
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Second messenger pathways in pulmonary host defense.
M. Monick, G. Hunninghake
2003Annual Review of Physiology36 citations
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Pulmonary Involvement in the Collagen Vascular Diseases1,2
G. Hunninghake, A. Fauci
201533 citations
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Does current knowledge explain the pathogenesis of idiopathic pulmonary fibrosis? A perspective.
G. Hunninghake, M. Schwarz
2007Proceedings of the American Thoracic Society33 citations Open access
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Lung parenchymal injury induced by bleomycin.
P. Moseley, D. Shasby, M. Brady, G. Hunninghake
2015American Review of Respiratory Disease30 citations
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Adenovirus vectors activate survival pathways in lung epithelial cells.
D. M. Flaherty, Sara L. Hinde, M. Monick, Linda S. Powers +3 more
2004American Journal of Physiology - Lung cellular and Molecular Physiology30 citations
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Extracellular signal-regulated kinase activation delays hyperoxia-induced epithelial cell death in conditions of Akt downregulation.
Son V. Truong, M. Monick, T. Yarovinsky, Linda S. Powers +2 more
2004American Journal of Respiratory Cell and Molecular Biology30 citations
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Intracellular Thiols Contribute to Th2 Function via a Positive Role in IL-4 Production 1
M. Monick, L. Samavati, N. Butler, M. Mohning +4 more
2003Journal of Immunology26 citations Open access
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