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I. Bertolini · SciRah

Researcher profile · Semantic Scholar

I. Bertolini

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I. Bertolini — researcher profile on SciRah

h-index: 12
Works: 34
Citations: 642

Most-cited papers

MITOCHONDRIAL Akt REGULATION OF HYPOXIC TUMOR REPROGRAMMING
Y. Chae, V. Vaira, M. C. Caino, Hsin-Yao Tang +15 more
2016Cancer Cell194 citations Open access
Semantic Scholar
The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
Jie Li, E. Agarwal, I. Bertolini, J. Seo +9 more
2020Science Signaling80 citations Open access
Semantic Scholar
The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma
A. Di Cristofori, S. Ferrero, I. Bertolini, G. Gaudioso +9 more
2015OncoTarget72 citations Open access
Semantic Scholar
A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes
I. Bertolini, A. Terrasi, C. Martelli, G. Gaudioso +10 more
2019EBioMedicine44 citations Open access
Semantic Scholar
SMALL EXTRACELLULAR VESICLE REGULATION OF MITOCHONDRIAL DYNAMICS REPROGRAMS A HYPOXIC TUMOR MICROENVIRONMENT
I. Bertolini, J. C. Ghosh, A. Kossenkov, Sudheer Mulugu +6 more
2020Developmental Cell41 citations Open access
Semantic Scholar
Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis
E. Agarwal, B. Altman, Jae Ho Seo, I. Bertolini +8 more
2019Molecular and Cellular Biology34 citations Open access
Semantic Scholar
IDH2 reprograms mitochondrial dynamics in cancer through a HIF‐1α‐regulated pseudohypoxic state
Yuan Wang, E. Agarwal, I. Bertolini, J. C. Ghosh +2 more
2019The FASEB Journal29 citations Open access
Semantic Scholar
Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability
J. C. Ghosh, Michela Perego, E. Agarwal, I. Bertolini +17 more
2022Proceedings of the National Academy of Sciences of the United States of America28 citations Open access
Semantic Scholar
Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo
A. Terrasi, I. Bertolini, C. Martelli, G. Gaudioso +8 more
2019EBioMedicine28 citations Open access
Semantic Scholar
Syntaphilin regulates neutrophil migration in cancer
Shuyu Fu, Hui Deng, I. Bertolini, Michela Perego +13 more
2022Cancer immunology research17 citations Open access
Semantic Scholar
Intercellular hif1α reprograms mammary progenitors and myeloid immune evasion to drive high-risk breast lesions
I. Bertolini, Michela Perego, Y. Nefedova, Cindy Lin +5 more
2023Journal of Clinical Investigation15 citations Open access
Semantic Scholar
NFκB ACTIVATION BY HYPOXIC SMALL EXTRACELLULAR VESICLES DRIVES ONCOGENIC REPROGRAMMING IN A BREAST CANCER MICROENVIRONMENT
I. Bertolini, Michela Perego, J. C. Ghosh, A. Kossenkov +1 more
2022Oncogene12 citations Open access
Semantic Scholar
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
M. Formica, A. Storaci, I. Bertolini, Francesca Carminati +3 more
2020bioRxiv11 citations Open access
Semantic Scholar
Parkin activates innate immunity and promotes antitumor immune responses
Michela Perego, Minjeong Yeon, E. Agarwal, Andrew T. Milcarek +11 more
2024Journal of Clinical Investigation8 citations Open access
Semantic Scholar
Protocol for assessing real-time changes in mitochondrial morphology, fission and fusion events in live cells using confocal microscopy
I. Bertolini, Frederick Keeney, D. Altieri
2021STAR Protocols8 citations Open access
Semantic Scholar
Parkin Induces Ubiquitination and Large Extracellular Vesicle Release of HMGB1 to Activate Antitumor Immunity
Minjeong Yeon, Michela Perego, Khaled M. Elokely, M. Abou-Gharbia +10 more
2025Cancer Research7 citations
Semantic Scholar
Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression
Minjeong Yeon, I. Bertolini, E. Agarwal, J. C. Ghosh +11 more
2023Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Interplay between V-ATPase G1 and small EV-miRNAs modulates ERK1/2 activation in GBM stem cells and non-neoplastic milieu
I. Bertolini, A. Storaci, A. Terrasi, A. Di Cristofori +5 more
2020Molecular Cancer Research5 citations Open access
Semantic Scholar
Advancements in extracellular vesicle research
Bing-Rui Li, V. S. Kalluri, Alissa M. Weaver, I. Bertolini +61 more
2026Extracellular Vesicle2 citations Open access
Semantic Scholar
Abstract PR003: Microglia derived extracellular vesicles in the crosstalk between glioblastoma and the periphery
I. Bertolini, Isabela Albuja Ron, M. Pulido
2026Cancer Research1 citations
Semantic Scholar
Speci ﬁ c V-ATPase expression sub-classi ﬁ es IDHwt lower-grade gliomas and impacts glioma growth in vivo
A. Terrasi, I. Bertolini, C. Martelli, G. Gaudioso +8 more
1 citations
Semantic Scholar
Microglia-derived Small Extracellular Vesicles Promote Bone Marrow Monocyte Expansion and Recruitment in Glioblastoma
Isabela Albuja, Miguel Quiralte, Neeharika Panda, Abigail Macaraeg +5 more
2026bioRxiv0 citations Open access
Semantic Scholar
IMMU-01. Microglia derived extracellular vesicles in the crosstalk between glioblastoma and infiltrating immune cells
I. Bertolini, M. Pulido, Isabela Albuja Ron
2025Neuro-Oncology0 citations
Semantic Scholar
3179eP Integrating vaccination into oncology care: A safe and feasible model in a real-world outpatient setting
M. Pino, I. Bertolini, M. Perna, C. Bacci +15 more
2025Annals of Oncology0 citations Open access
Semantic Scholar
Abstract 1276: Kindlin-2: a novel target of Parkin regulating cancer metastasis
Minjeong Yeon, I. Bertolini, Dario C. Altieri
2024Cancer Research0 citations
Semantic Scholar
Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment
I. Bertolini, Michela Perego, J. C. Ghosh, A. Kossenkov +1 more
2023Oncogene0 citations Open access
Semantic Scholar
Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment
I. Bertolini, Michela Perego, J. C. Ghosh, A. Kossenkov +1 more
2023Oncogene0 citations Open access
Semantic Scholar
The Communication of Extracellular Vesicles in Breast Cancer Progression
I. Bertolini
2020Oncology Times0 citations Open access
Semantic Scholar
NOTCH SIGNALLING PATHWAY PLAYS A CRUCIAL ROLE IN MAINTAINING THE CANCER STEM CELL POPULATION IN LUNG AND COLORECTAL CANCER
I. Bertolini, M. Caroli, S. Ferrero, V. Vaira +6 more
20190 citations
Semantic Scholar
Cancer Initiating Cells – Cancer Stem Cells PO -
I. Bertolini, M. Caroli, S. Ferrero, V. Vaira +5 more
20190 citations
Semantic Scholar
Abstract 791: V-ATPase in glioma stem cells: V1G1 subunit expression correlates with metabolic behavior and mitochondria activity
A. Storaci, I. Bertolini, M. Caroli, S. Ferrero +1 more
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
EXOSOMES SIGNALLING IN HUMAN GLIOMA STEM CELLS: THE CENTRAL ROLE OF V-ATPASE PROTON PUMP ACTIVITY
I. Bertolini
20180 citations
Semantic Scholar
PO-080 V-ATPase G1 expression in human glioma stem cells correlates with ERK activation
A. Storaci, I. Bertolini, M. Caroli, S. Ferrero +1 more
2018ESMO Open0 citations Open access
Semantic Scholar
Abstract 2889: V-ATPase control of EV signaling in glioma stem cells
I. Bertolini, A. Terrasi, A. Di Cristofori, S. Bosari +1 more
20170 citations Open access
Semantic Scholar

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D. Altieri×13
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D. Altieri — researcher profile on SciRah
V. Vaira×12
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V. Vaira — researcher profile on SciRah
J. C. Ghosh×12
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A. Kossenkov×11
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Michela Perego — researcher profile on SciRah

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