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F. Simabuco · SciRah

Researcher profile · Semantic Scholar

F. Simabuco

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F. Simabuco — researcher profile on SciRah

h-index: 24
Works: 129
Citations: 2,183

Most-cited papers

The Hallmarks of Flavonoids in Cancer
Luis Gustavo Saboia Ponte, I. Pavan, M. Mancini, Luiz Guilherme Salvino da Silva +4 more
2021Molecules150 citations Open access
Semantic Scholar
p53 and metabolism: from mechanism to therapeutics
F. Simabuco, M. Morale, I. Pavan, A. Morelli +2 more
2018OncoTarget131 citations Open access
Semantic Scholar
Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice.
S. C. Nakandakari, V. Muñoz, G. K. Kuga, R. C. Gaspar +10 more
2019Brain, behavior, and immunity119 citations
Semantic Scholar
Aerobic Exercise Training Induces the Mitonuclear Imbalance and UPRmt in the Skeletal Muscle of Aged Mice.
André V. Cordeiro, Rafael S. Brícola, R. Braga, Luciene Lenhare +10 more
2020The journals of gerontology. Series A, Biological sciences and medical sciences54 citations
Semantic Scholar
Pomegranate Juice and Peel Extracts are Able to Inhibit Proliferation, Migration and Colony Formation of Prostate Cancer Cell Lines and Modulate the Akt/mTOR/S6K Signaling Pathway
F. M. Chaves, I. Pavan, Luiz Guilherme Salvino da Silva, L. D. de Freitas +4 more
2019Plant Foods for Human Nutrition54 citations
Semantic Scholar
Survival, metabolic status and cellular morphology of probiotics in dairy products and dietary supplement after simulated digestion
Vivian Cristina da Cruz Rodrigues, Luiz Guilherme Salvino da Silva, F. Simabuco, K. Venema +1 more
2019Journal of Functional Foods52 citations Open access
Semantic Scholar
On Broken Ne(c)ks and Broken DNA: The Role of Human NEKs in the DNA Damage Response
I. Pavan, Andressa Peres de Oliveira, P. Dias, F. L. Basei +8 more
2021Cells44 citations Open access
Semantic Scholar
High-intensity exercise training induces mitonuclear imbalance and activates the mitochondrial unfolded protein response in the skeletal muscle of aged mice
André V. Cordeiro, Guilherme Francisco Peruca, R. Braga, Rafael S. Brícola +12 more
2020GeroScience40 citations Open access
Semantic Scholar
Maternal high-fat diet stimulates proinflammatory pathway and increases the expression of Tryptophan Hydroxylase 2 (TPH2) and brain-derived neurotrophic factor (BDNF) in adolescent mice hippocampus.
Clarissa Tavares Dias, Haidar Tafner Curi, T. Payolla, S. F. Lemes +5 more
2020Neurochemistry International35 citations Open access
Semantic Scholar
Characterization of pomegranate peel extracts obtained using different solvents and their effects on cell cycle and apoptosis in leukemia cells
L. Tamborlin, B. R. Sumere, M. C. de Souza, Nathalie Fortes Pestana +5 more
2020Food Science & Nutrition32 citations Open access
Semantic Scholar
Exhaustive acute exercise-induced ER stress is attenuated in IL-6-knockout mice.
A. P. Pinto, A. D. da Rocha, Eike B. Kohama, R. C. Gaspar +8 more
2019Journal of Endocrinology26 citations Open access
Semantic Scholar
Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism
C. Katashima, Thayana de Oliveira Micheletti, R. Braga, R. Gaspar +27 more
2022Science Advances25 citations Open access
Semantic Scholar
Beetroot and leaf extracts present protective effects against prostate cancer cells, inhibiting cell proliferation, migration, and growth signaling pathways
M. Mancini, Luis Gustavo Saboia Ponte, C. Silva, Isabella Fagundes +7 more
2021Phytotherapy Research25 citations
Semantic Scholar
Evaluation of some in vitro bioactivities of sunflower phenolic compounds
Thaís Dolfini Alexandrino, M. G. da Silva, R. Ferrari, Ana Lúcia Tasca Gois Ruiz +4 more
2021Current Research in Food Science25 citations Open access
Semantic Scholar
STAT3 contributes to cisplatin resistance, modulating EMT markers, and the mTOR signaling in lung adenocarcinoma
A. Morelli, T. Tortelli, M. Mancini, I. Pavan +13 more
2021Neoplasia24 citations Open access
Semantic Scholar
Protective effects of beet (Beta vulgaris) leaves extract against oxidative stress in endothelial cells in vitro
Luiz Guilherme Salvino Silva, A. Morelli, I. Pavan, M. Tavares +4 more
2020Phytotherapy Research24 citations
Semantic Scholar
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways
A. Morelli, T. Tortelli, I. Pavan, F. R. Silva +9 more
2021International Journal of Oncology23 citations Open access
Semantic Scholar
Modulation of the intestinal microbiota and the metabolites produced by the administration of ice cream and a dietary supplement containing the same probiotics
Vivian Cristina da Cruz Rodrigues, A. L. R. F. Duque, Luciana de Carvalho Fino, F. Simabuco +5 more
2020British Journal of Nutrition23 citations Open access
Semantic Scholar
Knockout of NRF2 triggers prostate cancer cells death through ROS modulation and sensitizes to cisplatin
M. Mancini, A. Morelli, M. B. Severino, I. Pavan +8 more
2022Journal of Cellular Biochemistry21 citations
Semantic Scholar
Exercise Counterbalances Rho/ROCK2 Signaling Impairment in the Skeletal Muscle and Ameliorates Insulin Sensitivity in Obese Mice
V. Muñoz, R. C. Gaspar, M. B. Severino, A. P. A. Macêdo +6 more
2021Frontiers in Immunology18 citations Open access
Semantic Scholar
High-intensity-exercise-induced intestinal damage is protected by fermented milk supplemented with whey protein, probiotic and pomegranate (Punica granatum L.)
F. M. Chaves, I. Baptista, F. Simabuco, Paula G. F. Quaresma +6 more
2018British Journal of Nutrition18 citations Open access
Semantic Scholar
Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells
C. D. Do Amaral, Ísis de Cássia Alves Martins, A. Veras, F. Simabuco +6 more
2022Cells17 citations Open access
Semantic Scholar
In vitro inhibition of glucose gastro-intestinal enzymes and antioxidant activity of hydrolyzed collagen peptides from different species.
Ana Laís Andrade Gaspardi, D. D. da Silva, Luis Gustavo Saboia Ponte, F. Galland +4 more
2022Journal of food biochemistry17 citations Open access
Semantic Scholar
Anticancer effects of root and beet leaf extracts (Beta vulgaris L.) in cervical cancer cells (HeLa)
S. A. Romero, I. Pavan, A. Morelli, M. Mancini +7 more
2021Phytotherapy Research17 citations
Semantic Scholar
Exercise alters the circadian rhythm of REV-ERB-α and downregulates autophagy-related genes in peripheral and central tissues
A. D. da Rocha, A. P. Pinto, B. Bedo, G. P. Morais +9 more
2022Scientific Reports16 citations Open access
Semantic Scholar
Tlr4 participates in the responses of markers of apoptosis, inflammation, and ER stress to different acute exercise intensities in mice hearts.
L. G. de Vicente, A. P. Pinto, V. Muñoz, Rafael L. Rovina +10 more
2019Life Science16 citations Open access
Semantic Scholar
NEK6 Regulates Redox Balance and DNA Damage Response in DU-145 Prostate Cancer Cells
I. Pavan, F. L. Basei, M. B. Severino, I. R. Silva +7 more
2023Cells15 citations Open access
Semantic Scholar
Combined physical exercise reverses the reduced expression of Bmal1 in the liver of aged mice.
A. P. Pinto, V. Muñoz, M. Tavares, J. R. Dos Santos +11 more
2022Life Science15 citations Open access
Semantic Scholar
Increased mTOR Signaling and Impaired Autophagic Flux Are Hallmarks of SARS-CoV-2 Infection
É. Zambalde, T. Dias, G. C. Maktura, M. R. Amorim +19 more
2022Current Issues in Molecular Biology15 citations Open access
Semantic Scholar
Regular swimming exercise prevented the acute and persistent mechanical muscle hyperalgesia by modulation of macrophages phenotypes and inflammatory cytokines via PPARγ receptors.
Graciana de Azambuja, C. O. Jorge, Beatriz B. Gomes, Hayla R Lourenço +2 more
2021Brain, behavior, and immunity15 citations
Semantic Scholar
The effects of aging on rho kinase and insulin signalling in skeletal muscle and white adipose tissue of rats.
V. Muñoz, R. C. Gaspar, G. K. Kuga, I. Pavan +6 more
2018The journals of gerontology. Series A, Biological sciences and medical sciences15 citations Open access
Semantic Scholar
Cdc2-like kinase 2 in the hypothalamus is necessary to maintain energy homeostasis
Paula G. F. Quaresma, L. Weissmann, T. M. Zanotto, A. C. Santos +7 more
2017International Journal of Obesity15 citations
Semantic Scholar
Molecular mechanisms and pharmacological interventions in the replication cycle of human coronaviruses
F. Simabuco, R. E. Tamura, I. Pavan, M. Morale +1 more
2020Genetics and Molecular Biology14 citations Open access
Semantic Scholar
Short-term strength exercise reduces the macrophage M1/M2 ratio in white adipose tissue of obese animals.
C. J. da Costa Fernandes, K. C. da Cruz Rodrigues, D. G. de Melo, T. D. P. de Campos +7 more
2023Life Science13 citations Open access
Semantic Scholar
Role of interleukin-6 in inhibiting hepatic autophagy markers in exercised mice.
A. P. Pinto, A. D. da Rocha, Elisa M. B. Cabrera, B. B. Marafon +9 more
2020Cytokine13 citations Open access
Semantic Scholar
Effect of a probiotic fermented milk supplementation on behavior and sleep
Samara M Freitas, B. Franco, G. Saragiotto, M. Morais +4 more
2023Nutritional neuroscience12 citations Open access
Semantic Scholar
Aqueous extract from Luehea divaricata Mart. leaves reduces nociception in rats with neuropathic pain.
A. Kroth, M. D. C. Q. Santos, Thaisla Cristiane Borella da Silva, E. M. S. Silveira +5 more
2020Journal of Ethnopharmacology12 citations
Semantic Scholar
Uncovering the bookshelves of CRISPR-based libraries: advances and applications in cancer studies.
Nathalia Quintero-Ruiz, Wesley de Lima Oliveira, M. V. Esteca, D. C. Granato +1 more
2024Critical reviews in oncology/hematology11 citations
Semantic Scholar
The respiratory syncytial virus M2-2 protein is targeted for proteasome degradation and inhibits translation and stress granules assembly
O. B. Scudero, V. F. Santiago, Giuseppe Palmisano, F. Simabuco +1 more
2023bioRxiv11 citations Open access
Semantic Scholar
IL-6 deletion decreased REV-ERBα protein and influenced autophagy and mitochondrial markers in the skeletal muscle after acute exercise
A. P. Pinto, V. Muñoz, A. D. da Rocha, Rafael L. Rovina +11 more
2022Frontiers in Immunology11 citations Open access
Semantic Scholar
Isolation and Sequencing of Cu-, Fe-, and Zn-Binding Whey Peptides for Potential Neuroprotective Applications as Multitargeted Compounds.
M. Caetano-Silva, F. Simabuco, R. Bezerra, D. D. da Silva +5 more
2020Journal of Agricultural and Food Chemistry11 citations
Semantic Scholar
Exhaustive exercise abolishes REV‐ERB‐α circadian rhythm and shifts the kynurenine pathway to a neurotoxic profile in mice
A. D. da Rocha, Ana Paula Pinto, I. V. de Sousa, V. Muñoz +10 more
2025Journal of Physiology10 citations
Semantic Scholar
Strength exercise reduces hepatic pyruvate carboxylase and gluconeogenesis in DIO mice.
R. M. Pereira, K. C. da Cruz Rodrigues, M. R. Sant'ana, Guilherme Francisco Peruca +7 more
2020Journal of Endocrinology10 citations Open access
Semantic Scholar
Point-of-Care Electrochemical Immunosensor Applied against Nosocomial Infection: Staphylococcus aureus Detection in Human Hand Skin.
H. A. de Godoy, A. M. Faria, N. Roza, L. Bach-Toledo +6 more
2024ACS Infectious Diseases9 citations
Semantic Scholar
Antioxidant and Neuroprotective Effects of the First Tryptophyllin Found in Snake Venom (Bothrops moojeni).
Anderson Dematei, S. Costa, D. Moreira, E. Barbosa +15 more
2022Journal of Natural Products9 citations Open access
Semantic Scholar
Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target
É. Zambalde, I. Pavan, M. Mancini, M. B. Severino +14 more
2022Frontiers in Cellular and Infection Microbiology9 citations Open access
Semantic Scholar
TLR4 deletion increases basal energy expenditure and attenuates heart apoptosis and ER stress but mitigates the training-induced cardiac function and performance improvement.
L. G. de Vicente, V. Muñoz, A. P. Pinto, Rafael L. Rovina +13 more
2021Life Science9 citations Open access
Semantic Scholar
Modulation of hypothalamic S6K1 and S6K2 alters feeding behavior and systemic glucose metabolism
M. Tavares, S. F. Lemes, Thaís de Fante, Cristina Saenz de Miera +6 more
2020Journal of Endocrinology9 citations Open access
Semantic Scholar
Correction: p53 and metabolism: from mechanism to therapeutics
F. Simabuco, M. Morale, I. Pavan, A. Morelli +2 more
2018OncoTarget9 citations Open access
Semantic Scholar
The role of interleukin-10 in mitigating endoplasmic reticulum stress in aged mice through exercise.
B. B. Marafon, Ana Paula Pinto, I. V. de Sousa, C. D. Da Luz +8 more
2024American Journal of Physiology. Endocrinology and Metabolism8 citations
Semantic Scholar

Frequent co-authors

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I. Pavan×18
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I. Pavan — researcher profile on SciRah
J. Pauli×18
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J. Pauli — researcher profile on SciRah
L. D. de Moura×16
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L. D. de Moura — researcher profile on SciRah
E. Ropelle×16
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E. Ropelle — researcher profile on SciRah

×15

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D. Cintra — researcher profile on SciRah

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R. Bezerra — researcher profile on SciRah

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A. Morelli — researcher profile on SciRah

A. S. D. da Silva×10

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A. S. D. da Silva — researcher profile on SciRah

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M. Mancini — researcher profile on SciRah

Luiz Guilherme Salvino da Silva×8

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Luiz Guilherme Salvino da Silva — researcher profile on SciRah

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V. Muñoz — researcher profile on SciRah

A. D. da Rocha×8

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A. D. da Rocha — researcher profile on SciRah