Researcher profile · Semantic Scholar

R. Iwakawa

h-index: 25
Works: 33
Citations: 5,907

Most-cited papers

Comprehensive genomic profiles of small cell lung cancer
J. George, Jing S. Lim, S. Jang, Yupeng Cun +92 more
2015Nature2,113 citations Open access
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Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas.
H. Okayama, T. Kohno, Y. Ishii, Yoko Shimada +17 more
2012Cancer Research845 citations Open access
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KIF5B-RET fusions in lung adenocarcinoma
T. Kohno, H. Ichikawa, Y. Totoki, K. Yasuda +25 more
2012Nature Medicine820 citations Open access
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Prevalence and specificity of LKB1 genetic alterations in lung cancers
S. Matsumoto, R. Iwakawa, Kenji Takahashi, T. Kohno +7 more
2007Oncogene282 citations Open access
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Frequent EGFR mutations in brain metastases of lung adenocarcinoma
S. Matsumoto, Kenji Takahashi, R. Iwakawa, Y. Matsuno +4 more
2006International Journal of Cancer203 citations
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Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis
S. Umemura, S. Mimaki, H. Makinoshima, S. Tada +17 more
2014Journal of Thoracic Oncology169 citations Open access
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MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.
Octavio A. Romero, M. Torres-Diz, E. Pros, S. Savola +9 more
2014Cancer Discovery165 citations
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A Gene-Alteration Profile of Human Lung Cancer Cell Lines
R. Blanco, R. Iwakawa, M. Tang, T. Kohno +6 more
2009Human Mutation127 citations Open access
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Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer
R. Iwakawa, M. Takenaka, T. Kohno, Yoko Shimada +8 more
2013Genes, Chromosomes and Cancer122 citations Open access
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Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer
J. George, M. Saito, K. Tsuta, R. Iwakawa +14 more
2016Clinical Cancer Research102 citations Open access
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A Catalog of Genes Homozygously Deleted in Human Lung Cancer and the Candidacy of PTPRD as a Tumor Suppressor Gene
T. Kohno, A. Otsuka, L. Girard, Masanori Sato +5 more
2010Genes, Chromosomes and Cancer97 citations Open access
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Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells.
B. Roy, T. Kohno, R. Iwakawa, T. Moriguchi +5 more
2010Lung Cancer96 citations
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MYC Amplification as a Prognostic Marker of Early-Stage Lung Adenocarcinoma Identified by Whole Genome Copy Number Analysis
R. Iwakawa, T. Kohno, Motohiro Kato, K. Shiraishi +4 more
2010Clinical Cancer Research92 citations
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KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.
Laia Simó-Riudalbas, Montserrat Pérez-Salvia, F. Setien, A. Villanueva +24 more
2015Cancer Research76 citations Open access
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Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing.
R. Iwakawa, T. Kohno, Y. Totoki, T. Shibata +14 more
2015Carcinogenesis76 citations Open access
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Oncogenic Ras/ERK Signaling Activates CDCP1 to Promote Tumor Invasion and Metastasis
Takamasa Uekita, S. Fujii, Yuri Miyazawa, R. Iwakawa +7 more
2014Molecular Cancer Research72 citations
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Overexpression of the DNA sensor proteins, absent in melanoma 2 and interferon‐inducible 16, contributes to tumorigenesis of oral squamous cell carcinoma with p53 inactivation
Yuudai Kondo, Kentaro Nagai, S. Nakahata, Y. Saito +9 more
2012Cancer Science72 citations Open access
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HPV-associated lung cancers: an international pooled analysis.
C. Ragin, Monisola Obikoya-Malomo, Sungjin Kim, Zheng-Jia Chen +36 more
2014Carcinogenesis71 citations Open access
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Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer.
H. Akça, A. Demiray, A. Yaren, F. Bir +4 more
2013Cancer Genetics48 citations
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Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma
S. Matsumoto, R. Iwakawa, T. Kohno, Kenji Suzuki +5 more
2006International Journal of Cancer47 citations Open access
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TSPAN2 is involved in cell invasion and motility during lung cancer progression.
Chihiro Otsubo, Ryo Otomo, M. Miyazaki, Y. Matsushima-Hibiya +12 more
2014Cell Reports37 citations Open access
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Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma
R. Iwakawa, T. Kohno, M. Enari, T. Kiyono +1 more
2010Cancer Science36 citations Open access
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Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas.
H. Nakanishi, S. Matsumoto, R. Iwakawa, T. Kohno +6 more
2009Cancer Research34 citations Open access
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Association of p16 Homozygous Deletions with Clinicopathologic Characteristics and EGFR/KRAS/p53 Mutations in Lung Adenocarcinoma
R. Iwakawa, T. Kohno, Y. Anami, M. Noguchi +6 more
2008Clinical Cancer Research34 citations Open access
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ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma
Y. Murata, Y. Minami, R. Iwakawa, J. Yokota +7 more
2014Cancer Science31 citations Open access
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Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.
M. Takenaka, M. Saito, R. Iwakawa, N. Yanaihara +7 more
2015International Journal of Oncology21 citations Open access
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Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma
R. Iwakawa, H. Okayama, T. Kohno, A. Sato-Otsubo +2 more
2012Genes, Chromosomes and Cancer21 citations
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KAT 6 B Is a Tumor Suppressor Histone H 3 Lysine 23 Acetyltransferase UndergoingGenomic Loss in Small Cell Lung Cancer
Laia Sim, o-Riudalbas, erez-Salvia, F. Setien +24 more
20154 citations
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Peer Review #2 of "A tropomyosin receptor kinase family protein, NTRK2 is a potential predictive biomarker for lung adenocarcinoma (v0.1)"
Xiang Wang, Zhi-Jie Xu, Xi Chen, Xin-Xin Ren +413 more
20190 citations Open access
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ECT2 serves as a new biomarker for early‐stage lung adenocarcinoma. A FISH image for a tumor showing high ECT2 amplification. Red signal shows the ECT2 gene, and green signal shows chromosome 3 enumeration.
Y. Murata, Y. Minami, R. Iwakawa, J. Yokota +7 more
20140 citations Open access
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Oncogenes and Tumor Suppressors Oncogenic Ras / ERK Signaling Activates CDCP 1 to Promote Tumor Invasion and Metastasis
Takamasa Uekita, S. Fujii, Yuri Miyazawa, R. Iwakawa +7 more
20140 citations
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Abstract B93: Gene fusions detected by whole transcriptome sequencing of lung adenocarcinoma.
T. Kohno, H. Ichikawa, Y. Totoki, K. Yasuda +16 more
20110 citations
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Association of P16 Homozygous Deletions with Clinicopathologic Characteristics and Egfr/kras/p53 Mutations in Lung Adenocarcinoma Human Cancer Biology Grant Support: Grants-in-aid from the Ministry of Health, Labor and Welfare for Thethird-term Comprehensive 10-year Strategy for Cancer Control and f
R. Iwakawa, T. Kohno
0 citations
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K. Shiraishi

×6

T. Shibata×6

M. Sanchez-Cespedes×5

H. Okayama×5

S. Ogawa×5

Y. Matsuno×5

T. Kiyono×5

Yoko Shimada×4