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D. Seldin · SciRah

Researcher profile · Semantic Scholar

D. Seldin

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D. Seldin — researcher profile on SciRah

h-index: 65
Works: 242
Citations: 14K

Most-cited papers

Repurposing Diflunisal for Familial Amyloid Polyneuropathy: A Randomized Clinical Trial
J. Berk, O. Suhr, L. Obici, Y. Sekijima +21 more
2013Journal of the American Medical Association (JAMA)680 citations Open access
Semantic Scholar
Amyloidosis: pathogenesis and new therapeutic options.
G. Merlini, D. Seldin, M. Gertz
2011Journal of Clinical Oncology477 citations Open access
Semantic Scholar
Heart Failure Due to Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study
L. Connors, F. Sam, M. Skinner, F. Salinaro +4 more
2015Circulation468 citations Open access
Semantic Scholar
Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis
R. Comenzo, D. Reece, G. Palladini, D. Seldin +13 more
2012Leukemia351 citations Open access
Semantic Scholar
Immunoglobulin light chain amyloidosis
G. Merlini, R. Comenzo, D. Seldin, A. Wechalekar +1 more
2014Expert Review of Hematology217 citations
Semantic Scholar
Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience
A. Cowan, M. Skinner, D. Seldin, J. Berk +4 more
2013Haematologica201 citations Open access
Semantic Scholar
First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction.
M. Gertz, H. Landau, R. Comenzo, D. Seldin +10 more
2016Journal of Clinical Oncology185 citations Open access
Semantic Scholar
Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish.
Shikha Mishra, J. Guan, E. Plovie, D. Seldin +5 more
2013American Journal of Physiology. Heart and Circulatory Physiology142 citations Open access
Semantic Scholar
Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis.
J. Ward, R. Ren, G. Toraldo, P. Soohoo +7 more
2011Blood139 citations Open access
Semantic Scholar
A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis.
V. Sanchorawala, G. Palladini, V. Kukreti, J. Zonder +11 more
2017Blood112 citations Open access
Semantic Scholar
Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity
J. Guan, Shikha Mishra, Yi-Ling Qiu, Jian-Ru Shi +9 more
2014EMBO Molecular Medicine112 citations Open access
Semantic Scholar
Kidney dysfunction during lenalidomide treatment for AL amyloidosis.
Richard Specter, V. Sanchorawala, D. Seldin, A. Shelton +4 more
2011Nephrology, Dialysis and Transplantation111 citations Open access
Semantic Scholar
The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells
E. Stanford, Zhong-Yan Wang, O. Novikov, F. Mulas +6 more
2016BMC Biology96 citations Open access
Semantic Scholar
Epithelial-to-Mesenchymal Transition Induced by TGF-β1 is Mediated by Blimp-1-Dependent Repression of BMP-5
M. Romagnoli, K. Belguise, Zi-Yang Yu, Xiao-Bo Wang +7 more
2012Cancer Research96 citations Open access
Semantic Scholar
END STAGE CARDIAC AMYLOIDOSIS: PREDICTORS OF SURVIVAL TO CARDIAC TRANSPLANTATION AND LONG TERM OUTCOMES
L. Gilstrap, Emily D. Niehaus, R. Malhotra, V. Ton +4 more
2013The Journal of Heart and Lung Transplantation76 citations Open access
Semantic Scholar
Longitudinal systolic strain, cardiac function improvement, and survival following treatment of light-chain (AL) cardiac amyloidosis
F. Salinaro, Hans K. Meier-Ewert, E. Miller, Shivda Pandey +4 more
2017European Heart Journal-Cardiovascular Imaging75 citations
Semantic Scholar
Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity
J. Guan, Shikha Mishra, Jian-Ru Shi, E. Plovie +16 more
2013Basic Research in Cardiology69 citations Open access
Semantic Scholar
Predictors of Mortality in Light Chain Cardiac Amyloidosis with Heart Failure
Usman Tahir, G. Doros, J. S. Kim, L. Connors +2 more
2019Scientific Reports56 citations Open access
Semantic Scholar
Myocardial infarction with “clean coronaries” caused by amyloid light-chain AL amyloidosis: a case report and literature review
S. Tsai, D. Seldin, Hao-Yiang Wu, C. O'Hara +2 more
2011Amyloid: Journal of Protein Folding Disorders50 citations
Semantic Scholar
Evidence for a functional role of the molecular chaperone clusterin in amyloidotic cardiomyopathy.
M. J. Greene, F. Sam, Pamela T. Soo Hoo, Rupesh S. Patel +2 more
2011American Journal of Pathology50 citations Open access
Semantic Scholar
Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial
V. Sanchorawala, J. Patel, J. Sloan, A. Shelton +2 more
2013Haematologica47 citations Open access
Semantic Scholar
Localized amyloidosis of the breast: a case series
M. Charlot, D. Seldin, C. O'Hara, M. Skinner +1 more
2011Amyloid: Journal of Protein Folding Disorders47 citations
Semantic Scholar
Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors
Xiaozhong Shi, D. Seldin, D. Garry
2012Biochemical Journal44 citations Open access
Semantic Scholar
Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity
J. Guan, Shikha Mishra, Yi-Ling Qiu, Jian-Ru Shi +9 more
2014EMBO Molecular Medicine40 citations Open access
Semantic Scholar
The patient’s perspective on the symptom and everyday life impact of AL amyloidosis
H. Lin, D. Seldin, A. Hui, D. Berg +2 more
2015Amyloid: Journal of Protein Folding Disorders39 citations
Semantic Scholar
CK2α is Essential for Embryonic Morphogenesis
I. Dominguez, I. Dégano, Kathleen Chea, J. Cha +2 more
2011Molecular and Cellular Biochemistry37 citations Open access
Semantic Scholar
Preclinical Development of siRNA Therapeutics for AL Amyloidosis
Beth M. Hovey, J. Ward, P. S. Hoo, C. O'Hara +2 more
2011Gene Therapy35 citations Open access
Semantic Scholar
Circulating Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Cardiac Amyloidosis
Komei Tanaka, Eric E. Essick, G. Doros, K. Tanriverdi +3 more
2013Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease34 citations Open access
Semantic Scholar
Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal
M. J. Greene, E. Klimtchuk, D. Seldin, J. Berk +1 more
2014Biochemistry32 citations Open access
Semantic Scholar
Lymphadenopathy as a manifestation of amyloidosis: a case series
Julie Fu, D. Seldin, J. Berk, F. Sun +3 more
2014Amyloid: Journal of Protein Folding Disorders29 citations
Semantic Scholar
Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis
K. Bever, Luke Masha, F. Sun, L. Stern +5 more
2016Haematologica26 citations Open access
Semantic Scholar
Clinical presentation and treatment responses in IgM-related AL amyloidosis*
M. Sissoko, V. Sanchorawala, D. Seldin, Brian Sworder +4 more
2015Amyloid: Journal of Protein Folding Disorders26 citations
Semantic Scholar
Developmental and growth defects in mice with combined deficiency of CK2 catalytic genes
E. Landesman-Bollag, Anna Belkina, Beth M. Hovey, Edward Connors +2 more
2011Molecular and Cellular Biochemistry25 citations Open access
Semantic Scholar
New hematologic response criteria predict survival in patients with immunoglobulin light chain amyloidosis treated with high-dose melphalan and autologous stem-cell transplantation.
S. Girnius, D. Seldin, M. Cibeira, V. Sanchorawala
2013Journal of Clinical Oncology24 citations Open access
Semantic Scholar
Depression and anxiety in patients with AL amyloidosis as assessed by the SF-36 questionnaire: experience in 1226 patients#
Janet E Shu, Stephen Lo, Margot Phillips, F. Sun +4 more
2016Amyloid: Journal of Protein Folding Disorders22 citations
Semantic Scholar
Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt)
J. L. Sikora, M. Logue, Gloria G Chan, Brian H. Spencer +4 more
2014Human Genetics22 citations Open access
Semantic Scholar
A new lysozyme tyr54asn mutation causing amyloidosis in a family of Swedish ancestry with gastrointestinal symptoms
S. Girnius, M. Skinner, Brian H. Spencer, T. Prokaeva +4 more
2012Amyloid: Journal of Protein Folding Disorders22 citations
Semantic Scholar
Overexpression of human amyloidogenic light chains causes heart failure in embryonic zebrafish: a preliminary report
Jordan T. Shin, J. Ward, P. A. Collins, Matthew Dai +3 more
2012Amyloid: Journal of Protein Folding Disorders22 citations
Semantic Scholar
Macroglossia – not always AL amyloidosis
A. Cowan, M. Skinner, J. Berk, J. Sloan +3 more
2011Amyloid: Journal of Protein Folding Disorders20 citations
Semantic Scholar
Amyloidotic Cardiomyopathy: Multidisciplinary Approach to Diagnosis and Treatment
D. Seldin, J. Berk, F. Sam, V. Sanchorawala
2011Heart Failure Clinics19 citations Open access
Semantic Scholar
CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells
Haiwei Lian, Dun Li, Yun Zhou, E. Landesman-Bollag +8 more
2017Haematologica18 citations Open access
Semantic Scholar
Plerixafor-augmented peripheral blood stem cell mobilization in AL amyloidosis with cardiac involvement: a case series
Steve Y. Lee, V. Sanchorawala, D. Seldin, J. Sloan +2 more
2014Amyloid: Journal of Protein Folding Disorders14 citations
Semantic Scholar
Amyloid Deposits in the Bone Marrow of Patients with AL Amyloidosis Do Not Impact Stem Cell Mobilization or Engraftment
A. Cowan, D. Seldin, M. Skinner, K. Quillen +5 more
2012Biology of Blood and Marrow Transplantation13 citations Open access
Semantic Scholar
Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes
María Valero Muñoz, Richard M. Wilson, Rosa Bretón Romero, Dominique Croteau +2 more
2020International Journal of Cardiology12 citations Open access
Semantic Scholar
Dysregulation of miRNAs in AL amyloidosis
Liangping Weng, Brian H. Spencer, Pamela T SoohHoo, L. Connors +2 more
2010Amyloid: Journal of Protein Folding Disorders12 citations Open access
Semantic Scholar
Cardiac and renal biomarker responses in a phase 1/2 study of NEOD001 in patients with AL amyloidosis and persistent organ dysfunction.
M. Gertz, H. Landau, R. Comenzo, D. Seldin +6 more
201511 citations
Semantic Scholar
The Oncogenic Potential of CK2
D. Seldin, E. Landesman-Bollag
201311 citations
Semantic Scholar
Immunoglobulin heavy light chain test quantifies clonal disease in patients with AL amyloidosis and normal serum free light chain ratio
T. Prokaeva, Brian H. Spencer, F. Sun, R. O'Hara +3 more
2016Amyloid: Journal of Protein Folding Disorders10 citations
Semantic Scholar
Lenalidomide and Dexamethasone in the Treatment of AL Amyloidosis: Final Results of A Phase II Trial
D. Nair, V. Sanchorawala, A. Shelton, Salli A. Fennessey +4 more
20128 citations
Semantic Scholar
Cancer-testis antigen expression and immunogenicity in AL amyloidosis
M. Rosenzweig, H. Landau, D. Seldin, C. O'Hara +10 more
2012Blood Cancer Journal8 citations Open access
Semantic Scholar

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M. Skinner — researcher profile on SciRah

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F. Sam — researcher profile on SciRah

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M. Gertz — researcher profile on SciRah

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F. Sun — researcher profile on SciRah

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R. Comenzo — researcher profile on SciRah

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R. Falk — researcher profile on SciRah

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J. Guan — researcher profile on SciRah