Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

T. Halazonetis · SciRah

Researcher profile · Semantic Scholar

T. Halazonetis

Share profile

T. Halazonetis — researcher profile on SciRah

h-index: 60
Works: 162
Citations: 25K

Most-cited papers

Genomic instability — an evolving hallmark of cancer
Simona Negrini, V. Gorgoulis, T. Halazonetis
2010Nature reviews. Molecular cell biology2,325 citations Open access
Semantic Scholar
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
V. Gorgoulis, L. Vassiliou, Panagiotis Karakaidos, Panayotis Zacharatos +11 more
2005Nature2,119 citations
Semantic Scholar
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
J. Bártková, Nousin Rezaei, M. Liontos, Panagiotis Karakaidos +21 more
2006Nature2,058 citations
Semantic Scholar
An Oncogene-Induced DNA Damage Model for Cancer Development
T. Halazonetis, V. Gorgoulis, J. Bartek
2008Science1,906 citations
Semantic Scholar
DNA replication stress as a hallmark of cancer.
Morgane Macheret, T. Halazonetis
2015Annual Review of Pathology775 citations Open access
Semantic Scholar
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Lorenzo Costantino, S. Sotiriou, J. Rantala, S. Magin +6 more
2013Science439 citations Open access
Semantic Scholar
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
S. Nikolaev, D. Rimoldi, C. Iseli, A. Valsesia +15 more
2011Nature Genetics426 citations Open access
Semantic Scholar
Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress
Morgane Macheret, T. Halazonetis
2018Nature380 citations Open access
Semantic Scholar
Emerging common themes in regulation of PIKKs and PI3Ks
Harri Lempiäinen, T. Halazonetis
2009EMBO Journal318 citations Open access
Semantic Scholar
SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response.
A. Peschiaroli, N. V. Dorrello, D. Guardavaccaro, M. Venere +3 more
2006Molecules and Cells309 citations Open access
Semantic Scholar
Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks
S. Sotiriou, Irene Kamileri, Natalia Lugli, K. Evangelou +12 more
2016Molecules and Cells247 citations Open access
Semantic Scholar
Oncogene-induced senescence: the bright and dark side of the response.
V. Gorgoulis, T. Halazonetis
2010Current Opinion in Cell Biology237 citations Open access
Semantic Scholar
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.
M. Liontos, M. Koutsami, M. Sideridou, K. Evangelou +14 more
2007Cancer Research225 citations Open access
Semantic Scholar
Transcription–replication conflicts underlie sensitivity to PARP inhibitors
Michalis Petropoulos, A. Karamichali, G. Rossetti, Alena Freudenmann +4 more
2024Nature173 citations Open access
Semantic Scholar
Genomic instability in induced stem cells
C. Pasi, Aygül Dereli-Öz, Simona Negrini, M. Friedli +9 more
2011Cell Death and Differentiation163 citations Open access
Semantic Scholar
Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication
F. Roumelioti, S. Sotiriou, Vasiliki Katsini, Maria Chiourea +2 more
2016EMBO Reports157 citations Open access
Semantic Scholar
Ultraviolet-B-mediated induction of protein–protein interactions in mammalian cells
R. P. Crefcoeur, Ruo-He Yin, R. Ulm, T. Halazonetis
2013Nature Communications141 citations Open access
Semantic Scholar
Human LATS1 is a mitotic exit network kinase.
J. Bothos, R. L. Tuttle, M. Ottey, F. Luca +1 more
2005Cancer Research135 citations Open access
Semantic Scholar
Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2
G. Loforese, Thomas Malinka, A. Keogh, F. Baier +5 more
2016EMBO Molecular Medicine124 citations Open access
Semantic Scholar
An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks
O. Zgheib, K. Pataky, J. Brugger, T. Halazonetis
2008Molecular and Cellular Biology124 citations Open access
Semantic Scholar
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer
G. Velimezi, M. Liontos, K. Vougas, Theodoros Roumeliotis +19 more
2013Nature Cell Biology120 citations Open access
Semantic Scholar
An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity
T. Petty, Soheila Emamzadah, Lorenzo Costantino, I. Petkova +4 more
2011EMBO Journal115 citations Open access
Semantic Scholar
High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing
Morgane Macheret, Rahul Bhowmick, Katarzyna Sobkowiak, Laura Padayachy +3 more
2020Cell Research101 citations Open access
Semantic Scholar
TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
R. Cescutti, Simona Negrini, M. Kohzaki, T. Halazonetis
2010EMBO Journal100 citations Open access
Semantic Scholar
ATM signaling and 53BP1.
O. Zgheib, Y. Huyen, R. Di Tullio, Andrew R. Snyder +3 more
2005Radiotherapy and Oncology95 citations
Semantic Scholar
Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress
Aygül Dereli-Öz, Gwennaelle Versini, T. Halazonetis
2011Molecular Oncology76 citations Open access
Semantic Scholar
Valosin-containing protein phosphorylation at Ser784 in response to DNA damage.
M. Livingstone, H. Ruan, J. Weiner, K. Clauser +12 more
2005Cancer Research70 citations Open access
Semantic Scholar
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas.
S. Nikolaev, S. Sotiriou, I. Pateras, F. Santoni +9 more
2012Cancer Research68 citations Open access
Semantic Scholar
R‐spondin 1 and noggin facilitate expansion of resident stem cells from non‐damaged gallbladders
Natalia Lugli, Irene Kamileri, A. Keogh, Thomas Malinka +6 more
2016EMBO Reports66 citations Open access
Semantic Scholar
The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus
Matthew K. Summers, J. Bothos, T. Halazonetis
2005Oncogene66 citations
Semantic Scholar
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening
Christoph Gorgulla, K. M. Padmanabha Das, K. Leigh, M. Cespugli +33 more
2021iScience57 citations Open access
Semantic Scholar
Molecular and Cellular Pathobiology Cancer Research 14-3-3 Binding Sites in the Snail Protein Are Essential for Snail-Mediated Transcriptional Repression and Epithelial-Mesenchymal Differentiation
Zhaoyuan Hou, Hongzhuang Peng, David E. White, Pu Wang +3 more
201057 citations
Semantic Scholar
Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits
G. Rossetti, M. Ossorio, S. Rempel, A. Kratzel +9 more
2022Scientific Reports55 citations Open access
Semantic Scholar
Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response Element
Soheila Emamzadah, L. Tropia, T. Halazonetis
2011Molecular Cancer Research54 citations
Semantic Scholar
Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas.
M. Liontos, Katerina Niforou, G. Velimezi, K. Vougas +13 more
2009American Journal of Pathology53 citations Open access
Semantic Scholar
DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chicken
M. Kohzaki, K. Nishihara, K. Hirota, E. Sonoda +6 more
2010Journal of Cell Biology49 citations Open access
Semantic Scholar
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
Florian J. Groelly, Rebecca A. Dagg, Michalis Petropoulos, G. Rossetti +15 more
2022Molecules and Cells48 citations Open access
Semantic Scholar
DNA replication stress as an Achilles' heel of cancer
Caterina Da-Ré, T. Halazonetis
2014OncoTarget48 citations Open access
Semantic Scholar
POLD3 is haploinsufficient for DNA replication in mice
M. Murga, E. Lecona, Irene Kamileri, Marcos Díaz +6 more
2016Molecules and Cells46 citations Open access
Semantic Scholar
RAD51 protects human cells from transcription-replication conflicts.
Rahul Bhowmick, Mads Lerdrup, S. A. Gadi, G. Rossetti +4 more
2022Molecules and Cells45 citations Open access
Semantic Scholar
Reversal of the DNA-binding-induced loop L1 conformational switch in an engineered human p53 protein.
Soheila Emamzadah, L. Tropia, I. Vincenti, B. Falquet +1 more
2014Journal of Molecular Biology45 citations Open access
Semantic Scholar
A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response
T. Schepeler, P. Lamy, V. Hvidberg, J. R. Laurberg +10 more
2013Oncogene37 citations Open access
Semantic Scholar
Monitoring early S-phase origin firing and replication fork movement by sequencing nascent DNA from synchronized cells
Morgane Macheret, T. Halazonetis
2018Nature Protocols33 citations Open access
Semantic Scholar
The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation.
M. Kohzaki, Maria Chiourea, Gwennaelle Versini, N. Adachi +3 more
2012Carcinogenesis31 citations Open access
Semantic Scholar
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening
Christoph Gorgulla, Krishna PadmanabhaDas, K. Leigh, M. Cespugli +33 more
2020ChemRxiv30 citations Open access
Semantic Scholar
Phosphorylation of ATR-interacting protein on Ser239 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function.
M. Venere, Andrew R. Snyder, O. Zgheib, T. Halazonetis
2007Cancer Research30 citations Open access
Semantic Scholar
Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1
Taisuke Nishimura, G. Molinard, T. Petty, Larissa Broger +4 more
2012PLoS Genetics28 citations Open access
Semantic Scholar
Defective in Mitotic Arrest 1/Ring Finger 8 Is a Checkpoint Protein That Antagonizes the Human Mitotic Exit Network
R. L. Tuttle, J. Bothos, Matthew K. Summers, F. Luca +1 more
2007Molecular Cancer Research26 citations Open access
Semantic Scholar
The role of SMARCAL1 in replication fork stability and telomere maintenance.
Natalia Lugli, S. Sotiriou, T. Halazonetis
2017DNA Repair25 citations Open access
Semantic Scholar
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage
Michalis Petropoulos, Spyridon Champeris Tsaniras, S. Nikou, Stella Maxouri +15 more
2022Journal of Pathology22 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

V. Gorgoulis×12
Invite
V. Gorgoulis — researcher profile on SciRah
S. Sotiriou×6
Invite
S. Sotiriou — researcher profile on SciRah
M. Venere×5
Invite
M. Venere — researcher profile on SciRah
J. Bartek×5
Invite
J. Bartek — researcher profile on SciRah

×4

Invite

A. Kotsinas — researcher profile on SciRah

Invite

D. Kletsas — researcher profile on SciRah

Invite

C. Kittas — researcher profile on SciRah

J. Bártková×4

Invite

J. Bártková — researcher profile on SciRah

Invite

M. Liontos — researcher profile on SciRah

Vassilis C. Zoumpourlis×4

Invite

Vassilis C. Zoumpourlis — researcher profile on SciRah

Morgane Macheret×4

Invite

Morgane Macheret — researcher profile on SciRah

Natalia Lugli×4

Invite

Natalia Lugli — researcher profile on SciRah