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T. Lemtalsi · SciRah

Researcher profile · Semantic Scholar

T. Lemtalsi

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T. Lemtalsi — researcher profile on SciRah

h-index: 17
Works: 64
Citations: 1,100

Most-cited papers

Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.
M. Al-Shabrawey, M. Bartoli, A. El-Remessy, Guo-Chuan Ma +4 more
2008Investigative Ophthalmology and Visual Science166 citations Open access
Semantic Scholar
Neuroprotection from retinal ischemia/reperfusion injury by NOX2 NADPH oxidase deletion.
H. Yokota, S. Narayanan, Wen-Bo Zhang, Hua Liu +8 more
2011Investigative Ophthalmology and Visual Science89 citations Open access
Semantic Scholar
Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1
E. Shosha, Zhimin Xu, S. Narayanan, T. Lemtalsi +6 more
2018International Journal of Molecular Sciences76 citations Open access
Semantic Scholar
NOX2-Induced Activation of Arginase and Diabetes-Induced Retinal Endothelial Cell Senescence
M. Rojas, T. Lemtalsi, H. Toque, Zhimin Xu +3 more
2017Antioxidants69 citations Open access
Semantic Scholar
Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism
S. Narayanan, Zhimin Xu, N. Putluri, A. Sreekumar +3 more
2012Cell Death and Disease69 citations Open access
Semantic Scholar
Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses
A. Fouda, Zhimin Xu, E. Shosha, T. Lemtalsi +11 more
2018Cell Death and Disease68 citations Open access
Semantic Scholar
Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury
M. Rojas, Wen-Bo Zhang, Zhimin Xu, T. Lemtalsi +4 more
2013PLoS ONE68 citations Open access
Semantic Scholar
Peroxynitrite increases VEGF expression in vascular endothelial cells via STAT3.
D. Platt, M. Bartoli, A. El-Remessy, M. Al-Shabrawey +3 more
2005Free Radical Biology & Medicine65 citations
Semantic Scholar
Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma
Y. Ha, H. Liu, Z. Xu, H. Yokota +6 more
2015Cell Death and Disease64 citations Open access
Semantic Scholar
Arginase as a Mediator of Diabetic Retinopathy
C. Patel, M. Rojas, S. Narayanan, Wen-Bo Zhang +5 more
2013Frontiers in Immunology52 citations Open access
Semantic Scholar
NAD(P)H Oxidase-Dependent Regulation of CCL2 Production during Retinal Inflammation
Wen-Bo Zhang, M. Rojas, B. Lilly, Nai-tse Tsai +4 more
2009Investigative Ophthalmology and Visual Science43 citations Open access
Semantic Scholar
Endothelial arginase 2 mediates retinal ischemia/reperfusion injury by inducing mitochondrial dysfunction
E. Shosha, A. Fouda, T. Lemtalsi, Stephen B. Haigh +5 more
2021Molecular Metabolism36 citations Open access
Semantic Scholar
Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2
Zhimin Xu, A. Fouda, T. Lemtalsi, E. Shosha +6 more
2018Frontiers in Neuroscience36 citations Open access
Semantic Scholar
Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway
Sally L Elshaer, Abdulrahman Alwhaibi, Riyaz Mohamed, T. Lemtalsi +3 more
2019Diabetologia34 citations Open access
Semantic Scholar
Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
A. Fouda, Zhimin Xu, J. Suwanpradid, M. Rojas +11 more
2022Cell Death and Disease27 citations Open access
Semantic Scholar
Role of Arginase 2 in Murine Retinopathy Associated with Western Diet-Induced Obesity
Reem T. Atawia, Katharine L. Bunch, A. Fouda, T. Lemtalsi +7 more
2020Journal of Clinical Medicine23 citations Open access
Semantic Scholar
High Glucose-Mediated Tyrosine Nitration of PI3-Kinase: A Molecular Switch of Survival and Apoptosis in Endothelial Cells
Sally L Elshaer, T. Lemtalsi, A. El-Remessy
2018Antioxidants21 citations Open access
Semantic Scholar
Angiotensin II limits NO production by upregulating arginase through a p38 MAPK - ATF-2 pathway
Alia Shatanawi, T. Lemtalsi, Lin Yao, C. Patel +2 more
2014European Journal of Pharmacology17 citations Open access
Semantic Scholar
Preclinical investigation of pegylated arginase 1 as a treatment for retina and brain injury
Abdelrahman Y. Fouda, Wael Eldahshan, Zhimin Xu, T. Lemtalsi +7 more
2021Experimental Neurology16 citations Open access
Semantic Scholar
Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
E. Shosha, Luke G. Qin, T. Lemtalsi, Syed A. H. Zaidi +5 more
2022Frontiers in Cardiovascular Medicine12 citations Open access
Semantic Scholar
Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization
Syed A. H. Zaidi, T. Lemtalsi, Zhimin Xu, I. Santana +5 more
2023Journal of Neuroinflammation11 citations Open access
Semantic Scholar
Inducible overexpression of endothelial proNGF as a mouse model to study microvascular dysfunction
Riyaz Mohamed, Maha Coucha, Sally L Elshaer, S. Artham +2 more
2017Biochimica et Biophysica Acta - Molecular Basis of Disease10 citations Open access
Semantic Scholar
Arginine deprivation/citrulline augmentation with ADI-PEG20 as novel therapy for complications in type 2 diabetes
Ammar A. Abdelrahman, Porsche V. Sandow, Jing Wang, Zhimin Xu +5 more
2024Molecular Metabolism8 citations Open access
Semantic Scholar
Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
Syed A. H. Zaidi, Zhimin Xu, T. Lemtalsi, Porsche V. Sandow +10 more
2023Cell Death and Disease7 citations Open access
Semantic Scholar
Decreased Nitric Oxide Bioavailability in Diabetic Retinopathy: Involvement of Arginase Activity
Ruth B. Caldwell, Wen-Bo Zhang, M. Rojas, M. Bartoli +6 more
20094 citations
Semantic Scholar
IL-6/STAT3 Pathway is Critically Involved in TNF-Alpha Induced Retinal Vascular Inflammation
Wen-Bo Zhang, C. Patel, M. Rojas, Zhimin Xu +5 more
20102 citations
Semantic Scholar
Novel Role of AcylCoA:cholesterol acyltransferase 1 (ACAT1/SOAT1) in Diabetic Retinopathy
Syed A. H. Zaidi, T. Lemtalsi, Zhi-Min Xu, Mai Yamamoto +5 more
2025bioRxiv1 citations
Semantic Scholar
Neuroprotection from optic nerve trauma by deletion of arginase 2
Zhimin Xu, A. Fouda, T. Lemtalsi, E. Shosha +5 more
2019The FASEB Journal1 citations
Semantic Scholar
Arginase 2 Overexpression Aggravates Ischemic Injury in Retinal Vascular Endothelial Cells
E. Shosha, T. Lemtalsi, A. Fouda, Stephen B. Haigh +4 more
2019The FASEB Journal1 citations
Semantic Scholar
Mechanisms of Retinal Ischemia/Reperfusion Injury: Arginase and the Mitochondria
E. Shosha, A. Fouda, T. Lemtalsi, Zhimin Xu +3 more
20181 citations
Semantic Scholar
Role of Arginase 1 in Diabetes‐Induced Senescence of Endothelial Cells and Macrophages
Zhimin Xu, E. Shosha, S. Narayanan, T. Lemtalsi +3 more
20151 citations
Semantic Scholar
Endoplasmic Reticulum Stress-regulated CXCL10/CXCR3 pathway mediates inflammation and neuronal injury after retinal ischemia
Y. Ha, Hua Liu, Zhimin Xu, H. Yokota +6 more
20141 citations
Semantic Scholar
Preservation of the Blood Retinal Barrier (BRB) in Diabetes by Deletion of gp91phox or Inhibition of NAD(P)H Oxidase
M. Al-Shabrawey, M. Rojas, M. Bartoli, A. El-Remessy +5 more
20061 citations
Semantic Scholar
Molecular Mechanisms of Oxidative Stress‐induced STAT3 Activation in Endothelial Cells
M. Bartoli, D. Platt, T. Lemtalsi, Azza El Remessy +3 more
20061 citations
Semantic Scholar
Abstract Wed172: Ornithine Decarboxylase Contributes to Endothelial Senescence and Vascular Barrier Dysfunction in a Mouse Model of Pathological Neovascularization
Syed A. H. Zaidi, Mai Yamamoto, Yusra Zaidi, T. Lemtalsi +6 more
2026Circulation Research0 citations
Semantic Scholar
PEG-Arginase 1: A Novel Therapy for Optic Nerve Injury
Mai Yamamoto, Syed A. H. Zaidi, T. Lemtalsi, Zhi-Min Xu +4 more
2026bioRxiv0 citations Open access
Semantic Scholar
Novel Role of AcylCoA: Cholesterol Acyltransferase 1/Sterol O-Acyltransferase 1 (ACAT1/SOAT1) in Diabetic Retinopathy
Syed A. H. Zaidi, T. Lemtalsi, Zhi-Min Xu, Mai Yamamoto +7 more
2026Investigative Ophthalmology and Visual Science0 citations Open access
Semantic Scholar
Modulation of TREM-1, Arginase and Nitric Oxide Levels under Diabetic Conditions in Macrophages
Alia Shatanawi, E. Alzayadneh, T. Lemtalsi, A. Fouda +2 more
2022Metabolism0 citations
Semantic Scholar
Study on Modulation of the p75 Neurotrophin Receptor Using LM11A-31 Prevents Diabetes-induced Retinal Vascular Permeability in Mice via Inhibition of Inflammation and the RhoA Kinase Pathway
Sally L Elshaer, Abdulrahman Alwhaibi, Riyaz Mohamed, T. Lemtalsi +3 more
20210 citations
Semantic Scholar
Advanced Glycated End Products or High Glucose/Palmitate treatment modulate TREM‐1, Arginase and Nitric Oxide Levels in Macrophages.
Alia Shatanawi, E. Alzayadneh, T. Lemtalsi, A. Fouda +2 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
Retinal Ischemia Reperfusion: Role of Arginase 2
E. Shosha, A. Fouda, A. Ibrahim, M. Al-Shabrawey +5 more
20170 citations
Semantic Scholar
Arginase 2 deletion prevents optic nerve crush-induced retinal degeneration
R. Caldwell, Zhimin Xu, S. Narayanan, T. Lemtalsi +3 more
20170 citations
Semantic Scholar
Abstract 21290: Adipose Tissue Factors and the Adipokine Resistin-Induce Vascular Endothelial Dysfunction via Arginase Upregulation
Reem T. Atawia, Ji-Jun Chen, H. Toque, T. Lemtalsi +2 more
2017Circulation0 citations
Semantic Scholar
Blockade of NOX2 or arginase prevents diabetes-induced retinal endothelial cell senescence by restoring NO bioavailability
M. Rojas, T. Lemtalsi, H. Toque, Zhimin Xu +4 more
20160 citations
Semantic Scholar
Polyamine oxidase: a novel mediator of hyperoxia-induced retinal neuro-vascular injury
C. Patel, Ji Xing, Zhimin Xu, T. Lemtalsi +4 more
20150 citations
Semantic Scholar
Mechanisms of Neurovascular protection in Retinal Ischemia Reperfusion Injury: Role of Arginase
E. Shosha, Zhimin Xu, T. Lemtalsi, S. Narayanan +1 more
20150 citations
Semantic Scholar
Diabetes induced-injury in retina and bone marrow cells involves NOX2-induced activation of arginase
M. Rojas, S. Narayanan, H. Toque, T. Lemtalsi +4 more
20140 citations
Semantic Scholar
Mechanistic role of arginase in inducing endothelial cell senescence in diabetic retinopathy
E. Shosha, T. Lemtalsi, Zhimin Xu, R. Caldwell +2 more
20140 citations
Semantic Scholar
Inhibition of polyamine oxidase reduces hyperoxia-mediated retinal neuro-vascular injury in a model of retinopathy of prematurity
S. Narayanan, Zhimin Xu, T. Lemtalsi, R. Caldwell +1 more
20140 citations
Semantic Scholar
Overactive Arginase Causes Mitochondrial Dysfunction and Premature Endothelial Cell Senescence during Diabetic Retinopathy
R. Caldwell, S. Narayanan, M. Rojas, T. Lemtalsi +5 more
20130 citations
Semantic Scholar

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Zhimin Xu×29
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R. Caldwell×23
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Ruth B. Caldwell

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