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T. Ohta · SciRah

Researcher profile · Semantic Scholar

T. Ohta

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T. Ohta — researcher profile on SciRah

h-index: 26
Works: 85
Citations: 3,102

Most-cited papers

Purification and Characterization of the Human Interleukin-18 Receptor*
K. Torigoe, S. Ushio, T. Okura, Susumu Kobayashi +10 more
1997Journal of Biological Chemistry531 citations Open access
Semantic Scholar
Synergy of IL-12 and IL-18 for IFN-γ Gene Expression: IL-12-Induced STAT4 Contributes to IFN-γ Promoter Activation by Up-Regulating the Binding Activity of IL-18-Induced Activator Protein 11
M. Nakahira, H. Ahn, W. Park, P. Gao +6 more
2002Journal of Immunology231 citations
Semantic Scholar
A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons.
H. Sakamoto, Hideo Yasukawa, M. Masuhara, Shyu Tanimura +10 more
1998Blood197 citations
Semantic Scholar
Interleukin-18 Activates NF-κB in Murine T Helper Type 1 Cells
S. Matsumoto, K. Tsuji‐Takayama, Y. Aizawa, K. Koide +3 more
1997193 citations
Semantic Scholar
Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells.
H. Kojima, M. Takeuchi, T. Ohta, Y. Nishida +4 more
1998Biochemical and Biophysical Research Communications - BBRC147 citations
Semantic Scholar
Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1.
M. Nakahira, H. Ahn, W. Park, P. Gao +6 more
2002Journal of Immunology142 citations
Semantic Scholar
Isolation and identification of compounds from Brazilian propolis which enhance macrophage spreading and mobility.
T. Tatefuji, N. Izumi, T. Ohta, Shigeyuki Arai +2 more
1996Biological and Pharmaceutical Bulletin125 citations Open access
Semantic Scholar
Immunohistochemical and immuno-electron-microscopic detection of interferon-γ-inducing factor (”interleukin-18”) in mouse intestinal epithelial cells
M. Takeuchi, Yasushi Nishizaki, O. Sano, T. Ohta +2 more
1997Cell and Tissue Research119 citations
Semantic Scholar
An Essential Role for NF-κB in IL-18-Induced IFN-γ Expression in KG-1 Cells
H. Kojima, Y. Aizawa, Y. Yanai, K. Nagaoka +5 more
1999Journal of Immunology106 citations Open access
Semantic Scholar
Regulation of glucose transporters in LLC-PK1 cells: effects of D-glucose and monosaccharides
T. Ohta, K. Isselbacher, David B. Rhoads
1990Molecular and Cellular Biology100 citations Open access
Semantic Scholar
Creation and X-ray Structure Analysis of the Tumor Necrosis Factor Receptor-1-selective Mutant of a Tumor Necrosis Factor-α Antagonist*
H. Shibata, Y. Yoshioka, A. Ohkawa, Kyoko Minowa +23 more
2008Journal of Biological Chemistry94 citations Open access
Semantic Scholar
An Absolute Requirement for STAT4 and a Role for IFN-γ as an Amplifying Factor in IL-12 Induction of the Functional IL-18 Receptor Complex1
M. Nakahira, M. Tomura, M. Iwasaki, H. Ahn +5 more
2001Journal of Immunology79 citations Open access
Semantic Scholar
Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant.
Y. Mukai, H. Shibata, Teruya Nakamura, Y. Yoshioka +10 more
2009Journal of Molecular Biology73 citations
Semantic Scholar
Intracellular production of interleukin-18 in human epithelial-like cell lines is enhanced by hyperosmotic stress in vitro
M. Takeuchi, T. Okura, T. Mori, K. Akita +4 more
1999Cell and Tissue Research68 citations
Semantic Scholar
Interleukin-18 activates NF-kappaB in murine T helper type 1 cells.
S. Matsumoto, K. Tsuji‐Takayama, Y. Aizawa, K. Koide +3 more
1997Biochemical and Biophysical Research Communications - BBRC61 citations
Semantic Scholar
The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF.
H. Shibata, Y. Yoshioka, Y. Abe, A. Ohkawa +9 more
2009Biomaterials56 citations
Semantic Scholar
Interleukin-18 induces activation and association of p56(lck) and MAPK in a murine TH1 clone.
Kazue Tsuji-Takayama, S. Matsumoto, K. Koide, M. Takeuchi +3 more
1997Biochemical and Biophysical Research Communications - BBRC56 citations
Semantic Scholar
Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.
T. Nomura, Y. Abe, H. Kamada, H. Shibata +17 more
2011Journal of Controlled Release52 citations
Semantic Scholar
The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models.
H. Shibata, Y. Yoshioka, A. Ohkawa, Y. Abe +9 more
2008Cytokine52 citations
Semantic Scholar
An essential role for NF-kappa B in IL-18-induced IFN-gamma expression in KG-1 cells.
H. Kojima, Y. Aizawa, Y. Yanai, K. Nagaoka +5 more
1999Journal of Immunology49 citations
Semantic Scholar
Cholesteryl Pullulan Encapsulated TNF-α Nanoparticles Are an Effective Mucosal Vaccine Adjuvant against Influenza Virus
Daiki Nagatomo, M. Taniai, Harumi Ariyasu, Mutsuko Taniguchi +4 more
2015BioMed Research International46 citations Open access
Semantic Scholar
Molecular Biology of Mammalian Glucose Transporters.
T. Ohta
199244 citations Open access
Semantic Scholar
Enhanced antioxidant defense due to extracellular catalase activity in Syrian hamster during arousal from hibernation.
Hitomi Ohta, Iwao Okamoto, T. Hanaya, Shigeyuki Arai +2 more
2006Comparative biochemistry and physiology. Toxicology & pharmacology : CBP41 citations
Semantic Scholar
Interleukin-18 Induces Interferon-γ Production through NF-κB and NFAT Activation in Murine T Helper Type 1 Cells
K. Tsuji‐Takayama, Y. Aizawa, I. Okamoto, H. Kojima +5 more
199941 citations
Semantic Scholar
Differentiation-dependent expression of the Na+/glucose cotransporter (SGLT1) in LLC-PK1 cells: role of protein kinase C activation and ongoing transcription.
Toshihiro Shioda, T. Ohta, K. Isselbacher, David B. Rhoads
1994Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Natural Human Interferon‐γ Derived from Lipopolysaccharide‐stimulated Human Myelomonocytic HBL‐38 Cells
S. Ando, T. Ohta, T. Tanimoto, O. Sano +4 more
1988Japanese journal of cancer research : Gann28 citations Open access
Semantic Scholar
Metastasis‐Promoting Activity of a Novel Molecule, Ag 243‐5, Derived from Mycoplasma, and the Complete Nucleotide Sequence
S. Ushio, K. Iwaki, M. Taniai, T. Ohta +3 more
1995Microbiology and immunology25 citations
Semantic Scholar
Neurotrophic Effects of a Cyanine Dye via the PI3K-Akt Pathway: Attenuation of Motor Discoordination and Neurodegeneration in an Ataxic Animal Model
Hitomi Ohta, Shigeyuki Arai, K. Akita, T. Ohta +1 more
2011PLoS ONE21 citations Open access
Semantic Scholar
Interleukin-18 induces interferon-gamma production through NF-kappaB and NFAT activation in murine T helper type 1 cells.
K. Tsuji‐Takayama, Y. Aizawa, I. Okamoto, H. Kojima +5 more
1999Cellular Immunology20 citations
Semantic Scholar
Proteasome-dependent degradation of cytosolic chaperonin CCT.
Shin-ichi Yokota, Tohru Kayano, T. Ohta, M. Kurimoto +3 more
2000Biochemical and Biophysical Research Communications - BBRC18 citations
Semantic Scholar
Cytochalasin D inhibits the progression from the Go to S phase at the mid-prereplicative stage in GC-7 cells stimulated with serum.
T. Ohta, Tsuyoshi Takasuka, Sadahiko Ishibashi, Toshinori Idei
1985Cell Structure and Function18 citations Open access
Semantic Scholar
Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists.
Y. Mukai, Teruya Nakamura, Y. Yoshioka, H. Shibata +9 more
2009Journal of Biochemistry (Tokyo)17 citations
Semantic Scholar
Regulation of Candida albicans morphogenesis by tumor necrosis factor-alpha and potential for treatment of oral candidiasis.
Hitomi Ohta, T. Tanimoto, M. Taniai, Mutsuko Taniguchi +4 more
2007In Vivo17 citations
Semantic Scholar
Interferon-γ Enhances Megakaryocyte Colony-Stimulating Activity in Murine Bone Marrow Cells
K. Tsuji‐Takayama, H. Tahata, A. Harashima, Y. Nishida +4 more
199617 citations
Semantic Scholar
Effects of NK-4 in a Transgenic Mouse Model of Alzheimer's Disease
Hitomi Ohta, Shigeyuki Arai, K. Akita, T. Ohta +1 more
2012PLoS ONE16 citations Open access
Semantic Scholar
Establishment of the cells useful for murine interleukin-18 bioassay by introducing murine interleukin-18 receptor cDNA into human myelomonocytic KG-1 cells.
Mutsuko Taniguchi, K. Nagaoka, S. Ushio, Yoshiyuki Nukada +6 more
1998JIM - Journal of Immunological Methods15 citations
Semantic Scholar
Cyanine dyes attenuate cerebral ischemia and reperfusion injury in rats.
Satomi Koya-Miyata, Hitomi Ohta, K. Akita, Shigeyuki Arai +3 more
2010Biological and Pharmaceutical Bulletin11 citations Open access
Semantic Scholar
Purification, identification, characterization, and cDNA cloning of a high molecular weight extracellular superoxide dismutase of hamster that transiently increases in plasma during arousal from hibernation.
K. Akita, T. Hanaya, Shigeyuki Arai, T. Ohta +2 more
2007Comparative biochemistry and physiology. Part A, Molecular & integrative physiology11 citations
Semantic Scholar
Suppressive effects of a cyanine dye against herpes simplex virus (HSV)-1 infection.
Chie Ushio, Harumi Ariyasu, T. Ariyasu, Shigeyuki Arai +2 more
2009Biomedical research10 citations Open access
Semantic Scholar
Role of p53 in the inhibitory effects of interferon-alpha subtypes on proliferation of hepatocellular carcinoma cells.
N. Fujioka, T. Ariyasu, Norie Arai, Harumi Ariyasu +7 more
2006Biomedical research9 citations Open access
Semantic Scholar
Generation of a monoclonal antibody that inhibits the procoagulant activity of various cancer cell lines
H. Inufusa, T. Adachi, Motoyuki Suzuki, O. Ando +5 more
1998Cancer9 citations Open access
Semantic Scholar
The cyanine Dye NK-4 improves scopolamine-induced memory impairments in mice.
S. Uchida, Shin Endo, K. Akita, T. Ohta +1 more
2012Biological and Pharmaceutical Bulletin8 citations Open access
Semantic Scholar
Novel protein engineering strategy for creating highly receptor-selective mutant TNFs.
T. Nomura, Y. Abe, H. Kamada, M. Inoue +15 more
2009Biochemical and Biophysical Research Communications - BBRC8 citations
Semantic Scholar
Creation of Interferon-α8 Mutants with Amino Acid Substitutions Against Interferon-α Receptor-2 Binding Sites Using Phage Display System and Evaluation of Their Biologic Properties
Kouzo Yamamoto, M. Taniai, K. Torigoe, Shigeto Yamamoto +16 more
2009Journal of Interferon and Cytokine Research8 citations
Semantic Scholar
SUPPRESSED NNA1 GENE EXPRESSION IN THE BRAIN OF ATAXIC SYRIAN HAMSTERS
K. Akita, Shigeyuki Arai, T. Ohta, T. Hanaya +1 more
2007Journal of neurogenetics8 citations
Semantic Scholar
Ley glycolipid acts as a co‐factor for tumor procoagulant activity
Motoyuki Suzuki, H. Inufusa, Shigeto Yamamoto, Tsuyoshi Hamada +5 more
1997International Journal of Cancer8 citations Open access
Semantic Scholar
Differential effects of N-acetyl-l-cysteine on IL-2- vs IL-12-driven proliferation of a T cell clone: implications for distinct signalling pathways.
C. Park, W. Park, N. Sugimoto, M. Nakahira +5 more
2000Cytokine7 citations
Semantic Scholar
Ingredients such as trehalose and hesperidin taken as supplements or foods reverse alterations in human T cells, reducing asbestos exposure-induced antitumor immunity
Shoko Yamamoto, Su-Ni Lee, T. Ariyasu, Shin Endo +11 more
2021International Journal of Oncology6 citations Open access
Semantic Scholar
Identification of the novel membrane-associated protein AgK114 on hamster keratinocytes recognized by a monoclonal antibody K114.
T. Tatefuji, Chikako Arai, T. Okura, Tohru Kayano +5 more
2004Biological and Pharmaceutical Bulletin6 citations Open access
Semantic Scholar
High expression of glycosphingolipids involved in procoagulant activity of cancer cells.
Motoyuki Suzuki, O. Ando, T. Ohta, H. Inufusa +3 more
1999Oncology Report6 citations
Semantic Scholar

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S. Fukuda×14
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M. Taniai×12
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M. Taniai — researcher profile on SciRah
M. Takeuchi×11
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M. Takeuchi — researcher profile on SciRah

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M. Ikeda — researcher profile on SciRah

Shigeyuki Arai×9

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H. Ikegami — researcher profile on SciRah

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H. Shibata — researcher profile on SciRah

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Y. Yoshioka — researcher profile on SciRah

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Y. Mukai — researcher profile on SciRah

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Y. Abe — researcher profile on SciRah

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T. Nomura — researcher profile on SciRah