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T. Fex · SciRah

Researcher profile · Semantic Scholar

T. Fex

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T. Fex — researcher profile on SciRah

h-index: 15
Works: 44
Citations: 917

Most-cited papers

Synthesis and biological evaluation of new 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for treatment of autoimmune disorders: structure-activity relationship.
Stig Jönsson, G. Andersson, T. Fex, T. Fristedt +9 more
2004Journal of Medicinal Chemistry148 citations
Semantic Scholar
Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli
A. Svensson, A. Larsson, H. Emtenäs, M. Hedenström +5 more
2001ChemBioChem136 citations
Semantic Scholar
Weak affinity chromatography as a new approach for fragment screening in drug discovery.
Minh-Dao Duong-Thi, Elinor Meiby, M. Bergström, T. Fex +2 more
2011Analytical Biochemistry76 citations
Semantic Scholar
Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa.
M. Buchanan, A. Carroll, Deborah Wessling, M. Jobling +9 more
2008Journal of Medicinal Chemistry69 citations Open access
Semantic Scholar
Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins.
Tobias Tengel, T. Fex, Hans Emtenas, F. Almqvist +2 more
2004Organic and biomolecular chemistry52 citations
Semantic Scholar
Label-Free Primary Screening and Affinity Ranking of Fragment Libraries Using Parallel Analysis of Protein Panels
Markku D. Hämäläinen, A. Zhukov, Marie Ivarsson, T. Fex +3 more
2008Journal of biomolecular screening50 citations Open access
Semantic Scholar
Use of 19F NMR spectroscopy to evaluate reactions in solid phase organic synthesis
A. Svensson, T. Fex, J. Kihlberg
199641 citations
Semantic Scholar
Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction.
Lei-Feng Cheng, D. Pettersen, B. Ohlsson, P. Schell +14 more
2014ACS Medicinal Chemistry Letters37 citations Open access
Semantic Scholar
High-Throughput Fragment Screening by Affinity LC-MS
Minh-Dao Duong-Thi, M. Bergström, T. Fex, R. Isaksson +1 more
2013Journal of biomolecular screening35 citations Open access
Semantic Scholar
Compounds binding to the S2-S3 pockets of thrombin.
M. Nilsson, Markku D. Hämäläinen, Marie Ivarsson, J. Gottfries +4 more
2009Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Fungal extractives. 10. An alternative synthesis of the velleral skeleton
T. Fex, Jan Froborg, G. Magnusson, S. Thorén
197626 citations
Semantic Scholar
Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5.
Roine I. Olsson, I. Jacobson, Jonas Boström, T. Fex +19 more
2013Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Fluorinated linkers for monitoring solid-phase synthesis using gel-phase 19F NMR spectroscopy
A. Svensson, K. Bergquist, T. Fex, J. Kihlberg
199823 citations
Semantic Scholar
Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa.
S. Hanessian, A. Larsson, T. Fex, W. Knecht +1 more
2010Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Comparison of weak affinity chromatography and surface plasmon resonance in determining affinity of small molecules.
Minh-Dao Duong-Thi, G. Bergström, C. Mandenius, M. Bergström +2 more
2014Analytical Biochemistry16 citations
Semantic Scholar
Structures of cytochalasin k, l and m, isolated from chalara microspora
T. Fex
198115 citations
Semantic Scholar
3-Aminopiperidine-Based Peptide Analogues as the First Selective Noncovalent Inhibitors of the Bacterial Cysteine Protease IdeS
K. Berggren, Reine Vindebro, C. Bergström, Christian Spoerry +5 more
2012Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Screening for transient biological interactions as applied to albumin ligands: a new concept for drug discovery.
S. Ohlson, Siamak Shoravi, T. Fex, R. Isaksson
2006Analytical Biochemistry14 citations
Semantic Scholar
Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function
J. Sandmark, Anna Tigerström, Tomas Åkerud, M. Althage +30 more
2020Journal of Biological Chemistry10 citations Open access
Semantic Scholar
STRUCTURE OF CHALOXONE, ISOLATED FROM A CHALARA SP
T. Fex, B. Wickberg, P. Krogsgaard‐Larsen, G. Pacifici +1 more
198110 citations Open access
Semantic Scholar
Weak Affinity Chromatography for Evaluation of Stereoisomers in Early Drug Discovery
Minh-Dao Duong-Thi, M. Bergström, T. Fex, Susanne Svensson +2 more
2013Journal of biomolecular screening9 citations Open access
Semantic Scholar
Synthesis and biological evaluation of reversible inhibitors of IdeS, a bacterial cysteine protease and virulence determinant.
Kristina Berggren, Björn P. Johansson, T. Fex, J. Kihlberg +2 more
2009Bioorganic & Medicinal Chemistry9 citations
Semantic Scholar
Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli.
A. Svensson, A. Larsson, Hans Emtenaes, M. Hedenstroem +5 more
20028 citations
Semantic Scholar
Toward high-throughput drug screening on a chip-based parallel affinity separation platform.
S. Ohlson, Minh-Dao Duong-Thi, M. Bergström, T. Fex +4 more
2010Journal of Separation Science7 citations
Semantic Scholar
STRUCTURE AND SYNTHESIS OF THE METHYL ESTER OF 3,4-ANHYDROSHIKIMIC ACID, ISOLATED FROM A CHALARA SP
T. Fex, J. Trofast, B. Wickberg, B. Olsson +1 more
19817 citations Open access
Semantic Scholar
New Hits as Antagonists of GPR103 Identified by HTS.
Anneli Nordqvist, Lisbeth Kristensson, Kjell E Johansson, Krystle Isaksson da Silva +4 more
2014ACS Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
Chalmicrin, a mannitol ether of methylated monocyclofarnesol, from Chalara microspora
T. Fex
19826 citations
Semantic Scholar
Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold.
D. Blomberg, T. Fex, Ya-Feng Xue, K. Brickmann +1 more
2007Organic and biomolecular chemistry4 citations
Semantic Scholar
A serendipitously identified novel small molecule procoagulant compound giving rise to a high-throughput screening assay based on human plasma.
D. Gustafsson, S. Nielsen, J. McPheat, F. Wågberg +6 more
2013Thrombosis Research3 citations
Semantic Scholar
A stereospecific synthesis of chaloxone
T. Fex
19813 citations
Semantic Scholar
Screening for Transient Biological Interactions: A New Concept for Drug Discovery
S. Ohlson, Siamak Shoravi, T. Fex, R. Isaksson
20052 citations
Semantic Scholar
X-Ray Study of Cytochalasin M, a Secondary Metabolite from the Fungus Chalara microspora.
J. Albertsson, T. Fex, C. Svensson
19812 citations Open access
Semantic Scholar
Plasminogen binding inhibitors demonstrate unwanted activities on GABAA and glycine receptors in human iPSC derived neurons.
Lisbeth Kristensson, Anders Lundin, D. Gustafsson, J. Fryklund +3 more
2018Neuroscience Letters1 citations Open access
Semantic Scholar
Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.
J. Sandmark, M. Althage, G. Andersson, T. Antonsson +29 more
20140 citations
Semantic Scholar
Protein Panels Label-Free Primary Screening and Affinity Ranking of Fragment Libraries Using Parallel Analysis of
Markku D. Hämäläinen, A. Zhukov, Marie Ivarsson, T. Fex +3 more
20130 citations
Semantic Scholar
Methods using weak interaction chromatography to separate and determine affinities of stereoisomers
S. Ohlson, Minh-Dao Duong-Thi, Elinor Meiby, R. Isaksson +1 more
20120 citations
Semantic Scholar
Derives de quinoline
A. Björk, Stig Jönsson, T. Fex, G. Hedlund
19990 citations
Semantic Scholar
Process for the preparation of novel therapeutically useful bisfenyylialkyylipiperatsiinijohdannaisten
T. Fex, K. Olsson, Aina Lisbeth Abramo, E. Christensson +1 more
19880 citations
Semantic Scholar
4- (bis-fluorphenylbutyl) -1- (pyridyl or pyrimidinyl) piperazine or 1,4-diazabicycloheptanforbindelser, process for their preparation, pharmaceutical compositions containing them and the use of the compounds
T. Fex, K. Olsson, Aina Lisbeth Abramo, E. Christensson +1 more
19880 citations
Semantic Scholar
Bisphenylalkylpiperazin derivatives, methods for production and drug preparation.
T. Fex, K. Olsson, Aina Lisbeth Abramo, E. Christensson +1 more
19880 citations
Semantic Scholar
Bisphenylalkylpiperazinderivater and process for production thereof
T. Fex, K. Olsson, Aina Lisbeth Abramo, E. Christensson +1 more
19880 citations
Semantic Scholar
Process for the preparation of substituted 1-piperazinecarboxamides and intermediates thereto
A. Bjoerk, Aina Lisbeth Abramo, T. Fex
19840 citations
Semantic Scholar
Metal Ion Oxidation. VIII. Oxidation of Organic Compounds by Copper(III).
L. Jönsson, T. Fex, C. Svensson
19810 citations Open access
Semantic Scholar
STRUCTURES OF CYTOCHALASIN K, L, AND M, ISOLATED FROM CHALARA MICROSPORA
T. Fex
19810 citations
Semantic Scholar

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