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R. Rustomjee · SciRah

Researcher profile · Semantic Scholar

R. Rustomjee

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R. Rustomjee — researcher profile on SciRah

h-index: 27
Works: 65
Citations: 6,878

Most-cited papers

Rapid Molecular Detection of Tuberculosis and Rifampin Resistance
C. Boehme, P. Nabeta, D. Hillemann, M. Nicol +15 more
2010New England Journal of Medicine2,437 citations Open access
Semantic Scholar
The diarylquinoline TMC207 for multidrug-resistant tuberculosis.
A. Diacon, A. Pym, M. Grobusch, R. Patientia +18 more
2009New England Journal of Medicine792 citations Open access
Semantic Scholar
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects
Alimuddin Zumla, Martin Rao, R. Wallis, S. Kaufmann +9 more
2016Lancet. Infectious Diseases (Print)370 citations Open access
Semantic Scholar
A four-month gatifloxacin-containing regimen for treating tuberculosis.
C. Merle, K. Fielding, O. Sow, A. N’Diaye +3 more
2015New England Journal of Medicine352 citations Open access
Semantic Scholar
A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.
R. Rustomjee, C. Lienhardt, T. Kanyok, G. Davies +9 more
2008The International Journal of Tuberculosis and Lung Disease319 citations
Semantic Scholar
What We Know About Tuberculosis Transmission: An Overview
G. Churchyard, P. Kim, N. Shah, R. Rustomjee +5 more
2017Journal of Infectious Diseases289 citations Open access
Semantic Scholar
Early Bactericidal Activity and Pharmacokinetics of the Diarylquinoline TMC207 in Treatment of Pulmonary Tuberculosis
R. Rustomjee, A. Diacon, J. Allen, A. Venter +10 more
2008Antimicrobial Agents and Chemotherapy287 citations Open access
Semantic Scholar
Tuberculosis--advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers.
R. Wallis, M. Maeurer, P. Mwaba, J. Chakaya +8 more
2016Lancet. Infectious Diseases (Print)252 citations Open access
Semantic Scholar
Drivers of Tuberculosis Transmission
B. Mathema, J. Andrews, T. Cohen, M. Borgdorff +5 more
2017Journal of Infectious Diseases175 citations Open access
Semantic Scholar
Towards host-directed therapies for tuberculosis
Alimuddin Zumla, J. Chakaya, M. Hoelscher, F. Ntoumi +61 more
2015Nature reviews. Drug discovery129 citations Open access
Semantic Scholar
The early bactericidal activities of rifampin and rifapentine in pulmonary tuberculosis.
F. Sirgel, P. B. Fourie, Peter R. Donald, N. Padayatchi +6 more
2005American Journal of Respiratory and Critical Care Medicine112 citations
Semantic Scholar
Reduced Antituberculosis Drug Concentrations in HIV-Infected Patients Who Are Men or Have Low Weight: Implications for International Dosing Guidelines
H. McIlleron, R. Rustomjee, Mahnaz Vahedi, T. Mthiyane +6 more
2012Antimicrobial Agents and Chemotherapy108 citations Open access
Semantic Scholar
A Semimechanistic Pharmacokinetic-Enzyme Turnover Model for Rifampin Autoinduction in Adult Tuberculosis Patients
W. Smythe, Akash Khandelwal, C. Merle, R. Rustomjee +9 more
2012Antimicrobial Agents and Chemotherapy102 citations Open access
Semantic Scholar
Effect of Standard Tuberculosis Treatment on Plasma Cytokine Levels in Patients with Active Pulmonary Tuberculosis
C. Riou, Blas Perez Peixoto, L. Roberts, K. Ronacher +7 more
2012PLoS ONE97 citations Open access
Semantic Scholar
Early versus delayed initiation of highly active antiretroviral therapy for HIV-positive adults with newly diagnosed pulmonary tuberculosis (TB-HAART): a prospective, international, randomised, placebo-controlled trial.
S. Mfinanga, B. Kirenga, D. Chanda, B. Mutayoba +24 more
2014Lancet. Infectious Diseases (Print)92 citations
Semantic Scholar
A four-month gatifloxacin-containing regimen for treating tuberculosis.
C. Merle, K. Fielding, O. Sow, M. Gninafon +15 more
2014New England Journal of Medicine92 citations Open access
Semantic Scholar
Treatment of tuberculosis: present status and future prospects.
P. Onyebujoh, Alimuddin Zumla, Isabella Ribeiro, R. Rustomjee +3 more
2005Bulletin of the World Health Organization92 citations
Semantic Scholar
Model-Based Evaluation of Higher Doses of Rifampin Using a Semimechanistic Model Incorporating Autoinduction and Saturation of Hepatic Extraction
M. Chirehwa, R. Rustomjee, T. Mthiyane, P. Onyebujoh +3 more
2015Antimicrobial Agents and Chemotherapy85 citations Open access
Semantic Scholar
Transmission of drug-resistant tuberculosis in HIV-endemic settings
P. Khan, T. Yates, M. Osman, R. Warren +12 more
2018Lancet. Infectious Diseases (Print)66 citations Open access
Semantic Scholar
Phase 1 trial of nonoxynol-9 film among sex workers in South Africa.
R. Rustomjee, Q. Karim, S. A. Abdool Karim, M. Laga +1 more
1999AIDS (London)61 citations Open access
Semantic Scholar
Use of a WHO-recommended algorithm to reduce mortality in seriously ill patients with HIV infection and smear-negative pulmonary tuberculosis in South Africa: an observational cohort study.
T. Holtz, Gaëtan M. Kabera, T. Mthiyane, T. Zingoni +6 more
2011Lancet. Infectious Diseases (Print)55 citations
Semantic Scholar
An introduction to the Marburg virus vaccine consortium, MARVAC
R. Cross, I. Longini, S. Becker, K. Bok +41 more
2022PLoS Pathogens45 citations Open access
Semantic Scholar
High Rates of Potentially Infectious Tuberculosis and Multidrug-Resistant Tuberculosis (MDR-TB) among Hospital Inpatients in KwaZulu Natal, South Africa Indicate Risk of Nosocomial Transmission
N. Bantubani, Gaëtan M. Kabera, C. Connolly, R. Rustomjee +3 more
2014PLoS ONE44 citations Open access
Semantic Scholar
A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting.
R. Rustomjee, A. Kharsany, C. Connolly, S. A. Abdool Karim
2002Journal of Antimicrobial Chemotherapy42 citations
Semantic Scholar
Pharmacokinetics of Pyrazinamide and Optimal Dosing Regimens for Drug-Sensitive and -Resistant Tuberculosis
M. Chirehwa, H. McIlleron, R. Rustomjee, T. Mthiyane +3 more
2017Antimicrobial Agents and Chemotherapy41 citations Open access
Semantic Scholar
Advances in the science of Mycobacterium tuberculosis transmission in HIV-endemic settings
Julian S. Peters, J. Andrews, M. Hatherill, S. Hermans +6 more
2018Lancet. Infectious Diseases (Print)39 citations Open access
Semantic Scholar
A pivotal registration phase III, multicenter, randomized tuberculosis controlled trial: design issues and lessons learnt from the Gatifloxacin for TB (OFLOTUB) project
C. Merle, C. Sismanidis, O. Sow, M. Gninafon +11 more
2012Trials34 citations Open access
Semantic Scholar
N-Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N-Acetyl-Isoniazid Pharmacokinetics during Antituberculosis Treatment
T. Mthiyane, J. Millard, John H Adamson, Y. Balakrishna +6 more
2020Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
Moving toward Tuberculosis Elimination. Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection
S. Keshavjee, F. Amanullah, A. Cattamanchi, R. Chaisson +28 more
2019American Journal of Respiratory and Critical Care Medicine22 citations Open access
Semantic Scholar
Research Roadmap for Tuberculosis Transmission Science: Where Do We Go From Here and How Will We Know When We’re There?
S. Auld, Anne G. Kasmar, D. Dowdy, B. Mathema +4 more
2017Journal of Infectious Diseases22 citations Open access
Semantic Scholar
The evolving research agenda for paediatric tuberculosis infection.
J. Seddon, E. Whittaker, B. Kampmann, Deborah A. Lewinsohn +4 more
2019Lancet. Infectious Diseases (Print)21 citations Open access
Semantic Scholar
Evaluation of Initial and Steady-State Gatifloxacin Pharmacokinetics and Dose in Pulmonary Tuberculosis Patients by Using Monte Carlo Simulations
W. Smythe, C. Merle, R. Rustomjee, M. Gninafon +8 more
2013Antimicrobial Agents and Chemotherapy21 citations Open access
Semantic Scholar
Improving tuberculosis control: an interdisciplinary approach.
C. Lienhardt, R. Rustomjee
2006The Lancet21 citations
Semantic Scholar
Evaluation of directly observed therapy for tuberculosis in KwaZulu-Natal, South Africa.
S. P. Ntshanga, R. Rustomjee, M. Mabaso
2009Transactions of the Royal Society of Tropical Medicine and Hygiene19 citations
Semantic Scholar
Vaccine Licensure in the Absence of Human Efficacy Data
Courtney L. Finch, C. Martinez, E. Leffel, M. Skiadopoulos +6 more
2022Vaccines16 citations Open access
Semantic Scholar
Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa
Jennifer R. Lim, N. Gandhi, T. Mthiyane, K. Mlisana +7 more
2015PLoS ONE14 citations Open access
Semantic Scholar
Middle East Respiratory Syndrome - need for increased vigilance and watchful surveillance for MERS-CoV in sub-Saharan Africa
Alimuddin Zumla, R. Rustomjee, F. Ntoumi, P. Mwaba +4 more
2015International Journal of Infectious Diseases13 citations Open access
Semantic Scholar
Designing an adaptive phase II/III trial to evaluate efficacy, safety and immune correlates of new TB vaccines in young adults and adolescents.
R. Rustomjee, B. McClain, Michael J. Brennan, R. McLeod +10 more
2013Tuberculosis11 citations
Semantic Scholar
Bridging Animal and Human Data in Pursuit of Vaccine Licensure
Courtney L. Finch, W. Dowling, T. King, C. Martinez +7 more
2022Vaccines10 citations Open access
Semantic Scholar
Novel licensure pathways for expeditious introduction of new tuberculosis vaccines: a discussion of the adaptive licensure concept.
R. Rustomjee, S. Lockhart, J. E. Shea, P. B. Fourie +5 more
2014Tuberculosis10 citations Open access
Semantic Scholar
Urine lipoarabinomannan (LAM) and antimicrobial usage in seriously-ill HIV-infected patients with sputum smear-negative pulmonary tuberculosis.
T. Mthiyane, J. Peter, J. Allen, C. Connolly +5 more
2019Journal of Thoracic Disease9 citations Open access
Semantic Scholar
Longitudinal assessment of health related quality of life of HIV infected patients treated for tuberculosis and HIV in a high burden setting
T. Mthiyane, A. Pym, K. Dheda, R. Rustomjee +2 more
2016Quality of Life Research8 citations
Semantic Scholar
Microbicide Research and Development—Where To?
R. Rustomjee, Q. Abdool Karim
2001HIV Clinical Trials8 citations
Semantic Scholar
RESOURCE UTILIZATION FOR MULTIDRUG-RESISTANT TUBERCULOSIS HOUSEHOLD CONTACT INVESTIGATIONS (A5300/I2003)
S. Swindells, Amita Gupta, Soyeon Kim, M. Hughes +11 more
2018The International Journal of Tuberculosis and Lung Disease4 citations Open access
Semantic Scholar
Getting to Zero New Tuberculosis Infections: Insights From the National Institutes of Health/US Centers for Disease Control and Prevention/Bill & Melinda Gates Foundation Workshop on Research Needs for Halting Tuberculosis Transmission
N. Shah, P. Kim, B. Kana, R. Rustomjee
2017Journal of Infectious Diseases4 citations Open access
Semantic Scholar
Key issues in the clinical development and implementation of TB vaccines in South Africa.
R. Rustomjee, R. McLeod, W. Hanekom, G. Steel +15 more
2012Tuberculosis4 citations Open access
Semantic Scholar
Early bactericidal activity, tolerability, and pharmacokinetics of the investigational diarylquinoline TMC207
A. Diacon, R. Rustomjee, D. Mcneeley, R. Kerstens +2 more
20064 citations
Semantic Scholar
Pharmacokinetics of ethambutol and weight banded dosing in South African adults newly diagnosed with tuberculosis and HIV
B. Ndzamba, P. Denti, H. McIlleron, Peter C. Smith +4 more
2024Antimicrobial Agents and Chemotherapy3 citations Open access
Semantic Scholar
Erratum for Chirehwa et al., Model-Based Evaluation of Higher Doses of Rifampin Using a Semimechanistic Model Incorporating Autoinduction and Saturation of Hepatic Extraction
M. Chirehwa, R. Rustomjee, T. Mthiyane, P. Onyebujoh +3 more
2016Antimicrobial Agents and Chemotherapy3 citations Open access
Semantic Scholar
Safety, tolerability, immunogenicity, and plasmapheresis-based antibody collection in a phase 1b open label trial of two investigational monovalent chimpanzee adenoviral vectored filovirus vaccines, cAd3-Sudan and cAd3-Marburg, in healthy adults
Ekaterina Vert-Wong, Michael Stevenson, R. Rustomjee, Courtney L. Finch +2 more
2025EBioMedicine2 citations Open access
Semantic Scholar

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