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M. Hedger · SciRah

Researcher profile · Semantic Scholar

M. Hedger

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M. Hedger — researcher profile on SciRah

h-index: 50
Works: 209
Citations: 8,125

Most-cited papers

Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia
K. Jones, A. Mansell, S. Patella, B. Scott +3 more
2007Proceedings of the National Academy of Sciences of the United States of America280 citations Open access
Semantic Scholar
Immunological, paracrine and endocrine aspects of testicular immune privilege.
A. Meinhardt, M. Hedger
2011Molecular and Cellular Endocrinology250 citations
Semantic Scholar
Infectious, inflammatory and ‘autoimmune’ male factor infertility: how do rodent models inform clinical practice?
M. Fijak, A. Pilatz, M. Hedger, Nour Nicolas +5 more
2018Human Reproduction Update243 citations Open access
Semantic Scholar
Immunophysiology and Pathology of Inflammation in the Testis and Epididymis
M. Hedger
2011Journal of Andrology227 citations Open access
Semantic Scholar
Correlation between Blood Activin Levels and Clinical Parameters of Type 2 Diabetes
Hui Wu, Michael Wu, Yi Chen, C. Allan +2 more
2012International Journal of Experimental Diabetes Research189 citations Open access
Semantic Scholar
Cytokines in Male Fertility and Reproductive Pathologies: Immunoregulation and Beyond
K. Loveland, B. Klein, D. Pueschl, S. Indumathy +4 more
2017Frontiers in Endocrinology186 citations Open access
Semantic Scholar
The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair.
D. de Kretser, Robyn E. O'Hehir, C. L. Hardy, M. Hedger
2012Molecular and Cellular Endocrinology176 citations
Semantic Scholar
The regulation and functions of activin and follistatin in inflammation and immunity.
M. Hedger, W. Winnall, D. J. Phillips, D. de Kretser
2011Vitamins and hormones170 citations
Semantic Scholar
Activin and related proteins in inflammation: not just interested bystanders.
D. J. Phillips, D. de Kretser, M. Hedger
2009Cytokine & growth factor reviews164 citations
Semantic Scholar
The activins and their binding protein, follistatin-Diagnostic and therapeutic targets in inflammatory disease and fibrosis.
M. Hedger, D. de Kretser
2013Cytokine & growth factor reviews138 citations
Semantic Scholar
Rat resident testicular macrophages have an alternatively activated phenotype and constitutively produce interleukin‐10 in vitro
W. Winnall, J. Muir, M. Hedger
2011Journal of Leukocyte Biology138 citations
Semantic Scholar
Specific immune cell and cytokine characteristics of human testicular germ cell neoplasia.
B. Klein, T. Haggeney, D. Fietz, S. Indumathy +6 more
2016Human Reproduction96 citations Open access
Semantic Scholar
Toll-like receptors and signalling in spermatogenesis and testicular responses to inflammation—a perspective
M. Hedger
2011Journal of Reproductive Immunology95 citations Open access
Semantic Scholar
Regulation of activin and inhibin in the adult testis and the evidence for functional roles in spermatogenesis and immunoregulation.
M. Hedger, W. Winnall
2012Molecular and Cellular Endocrinology92 citations
Semantic Scholar
Phenotypic and functional heterogeneity of the testicular macrophage population: a new regulatory model.
W. Winnall, M. Hedger
2013Journal of Reproductive Immunology76 citations
Semantic Scholar
The human dimension of climate adaptation: the importance of local and institutional issues.
I. Christoplos, S. Anderson, M. Arnold, V. Galaz +3 more
200975 citations
Semantic Scholar
Epididymitis: revelations at the convergence of clinical and basic sciences
V. Michel, A. Pilatz, M. Hedger, A. Meinhardt
2015Asian Journal of Andrology72 citations Open access
Semantic Scholar
Differential responses of epithelial Sertoli cells of the rat testis to Toll-like receptor 2 and 4 ligands: Implications for studies of testicular inflammation using bacterial lipopolysaccharides
W. Winnall, J. Muir, M. Hedger
2011Innate Immunity70 citations Open access
Semantic Scholar
Inflammatory networks in the control of spermatogenesis : chronic inflammation in an immunologically privileged tissue?
M. O'Bryan, M. Hedger
2008Advances in Experimental Medicine and Biology68 citations
Semantic Scholar
Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging.
A. Lepletier, M. Hun, M. Hammett, Kahlia Wong +4 more
2019Cell Reports54 citations Open access
Semantic Scholar
Epididymal cysteine-rich secretory proteins are required for epididymal sperm maturation and optimal sperm function
Jing-Hua Hu, D. J. Merriner, A. O'Connor, B. Houston +3 more
2018Molecular human reproduction49 citations
Semantic Scholar
Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo–orchitis in mice
Nour Nicolas, V. Michel, S. Bhushan, E. Wahle +8 more
2017Scientific Reports48 citations Open access
Semantic Scholar
The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection
M. Shehu-Xhilaga, S. Kent, Jane Batten, S. Ellis +5 more
2007Retrovirology46 citations Open access
Semantic Scholar
Differential tissue-specific damage caused by bacterial epididymo-orchitis in the mouse
B. Klein, S. Bhushan, Stefan Günther, R. Middendorff +3 more
2020Molecular human reproduction41 citations Open access
Semantic Scholar
The Immunophysiology of Male Reproduction
M. Hedger
2014Knobil and Neill's Physiology of Reproduction39 citations
Semantic Scholar
Hyperglycemia is associated with reduced testicular function and activin dysregulation in the Ins2Akita+/- mouse model of type 1 diabetes.
Constanze C. Maresch, Dina C. Stute, H. Ludlow, H. Hammes +3 more
2017Molecular and Cellular Endocrinology38 citations
Semantic Scholar
Serum activin A and B levels predict outcome in patients with acute respiratory failure: a prospective cohort study
D. de Kretser, J. Bensley, V. Pettilä, R. Linko +6 more
2013Critical Care38 citations Open access
Semantic Scholar
Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study
B. Lidbury, Badia Kita, D. Lewis, S. Hayward +3 more
2017Journal of Translational Medicine35 citations Open access
Semantic Scholar
The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology
C. L. Hardy, S. King, N. Mifsud, M. Hedger +6 more
2015Immunology and Cell Biology33 citations Open access
Semantic Scholar
Acute regulation of activin A and its binding protein, follistatin, in serum and tissues following lipopolysaccharide treatment of adult male mice.
Hui Wu, Yi Chen, W. Winnall, D. J. Phillips +1 more
2012American Journal of Physiology. Regulatory Integrative and Comparative Physiology33 citations
Semantic Scholar
Prepubertal Di-n-Butyl Phthalate Exposure Alters Sertoli and Leydig Cell Function and Lowers Bone Density in Adult Male Mice.
Amanda Bielanowicz, Rachelle W. Johnson, Hoey Goh, S. Moody +6 more
2016Endocrinology32 citations Open access
Semantic Scholar
Regulation and actions of activin A and follistatin in myocardial ischaemia-reperfusion injury.
Yi Chen, C. Rothnie, Denise J. Spring, E. Verrier +5 more
2014Cytokine32 citations
Semantic Scholar
Characterisation of macaque testicular leucocyte populations and T-lymphocyte immunity.
R. De Rose, C. Fernandez, M. Hedger, S. Kent +1 more
2013Journal of Reproductive Immunology32 citations Open access
Semantic Scholar
Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats.
W. Winnall, J. Muir, S. Liew, J. Hirst +2 more
2009International Journal of Andrology30 citations Open access
Semantic Scholar
The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis
C. Pleuger, D. Ai, Minea Hoppe, Laura Winter +13 more
2022bioRxiv29 citations Open access
Semantic Scholar
Expression patterns of activin, inhibin and follistatin variants in the adult male mouse reproductive tract suggest important roles in the epididymis and vas deferens.
W. Winnall, Hui Wu, M. A. Sarraj, P. Rogers +3 more
2013Reproduction, Fertility and Development29 citations
Semantic Scholar
Activin A and CCR2 regulate macrophage function in testicular fibrosis caused by experimental autoimmune orchitis
W. Peng, Artem Kepsch, Till O. Kracht, Hiba Hasan +15 more
2022Cellular and Molecular Life Sciences28 citations Open access
Semantic Scholar
Relationships among body composition, circulating concentrations of leptin and follistatin, and the onset of puberty and fertility in young female sheep.
César A Rosales Nieto, A. Thompson, C. Macleay, J. Briegel +3 more
2014Animal Reproduction Science28 citations
Semantic Scholar
Induction of experimental autoimmune orchitis in mice: responses to elevated circulating levels of the activin-binding protein, follistatin.
Nour Nicolas, J. Muir, S. Hayward, Justin L. Chen +8 more
2017Reproduction25 citations
Semantic Scholar
Acute heat-treatment disrupts inhibin-related protein production and gene expression in the adult rat testis.
R. A. Aldahhan, P. Stanton, H. Ludlow, D. de Kretser +1 more
2019Molecular and Cellular Endocrinology24 citations
Semantic Scholar
Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection
R. Linko, M. Hedger, V. Pettilä, E. Ruokonen +3 more
2014BMC Infectious Diseases24 citations Open access
Semantic Scholar
An RNA spiking method demonstrates that 18S rRNA is regulated by progesterone in the mouse uterus.
R. G. Craythorn, J. Girling, M. Hedger, Peter A. W. Rogers +1 more
2009Molecular human reproduction24 citations
Semantic Scholar
The testicular transcriptome associated with spermatogonia differentiation initiated by gonadotrophin stimulation in the juvenile rhesus monkey (Macaca mulatta)
S. Ramaswamy, W. Walker, P. Aliberti, Rahil Sethi +7 more
2017Human Reproduction23 citations Open access
Semantic Scholar
Regulation of Sertoli cell activin A and inhibin B by tumour necrosis factor α and interleukin 1α: interaction with follicle-stimulating hormone/adenosine 3',5'-cyclic phosphate signalling.
K. Saito, W. Winnall, J. Muir, M. Hedger
2011Molecular and Cellular Endocrinology22 citations
Semantic Scholar
Region-specific immune responses to autoimmune epididymitis in the murine reproductive tract
R. Wijayarathna, Alen Pasalic, Nour Nicolas, Sneha Biniwale +7 more
2020Cell and Tissue Research21 citations
Semantic Scholar
Investigation of activin A in inflammatory responses of the testis and its role in the development of testicular fibrosis.
A. C. Kauerhof, Nour Nicolas, S. Bhushan, E. Wahle +10 more
2019Human Reproduction21 citations
Semantic Scholar
Regulation of activin A release from murine bone marrow-derived neutrophil precursors by tumour necrosis factor-α and insulin.
Hui Wu, Yi Chen, W. Winnall, D. J. Phillips +1 more
2013Cytokine19 citations
Semantic Scholar
Rethinking ME/CFS Diagnostic Reference Intervals via Machine Learning, and the Utility of Activin B for Defining Symptom Severity
B. Lidbury, Badia Kita, A. Richardson, D. Lewis +4 more
2019Diagnostics16 citations Open access
Semantic Scholar
Dexamethasone improves therapeutic outcomes in a preclinical bacterial epididymitis mouse model.
B. Klein, S. Pant, S. Bhushan, Julia Kautz +8 more
2019Human Reproduction16 citations Open access
Semantic Scholar
Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection
A. Richardson, D. Lewis, Badia Kita, H. Ludlow +4 more
2018Journal of Translational Medicine16 citations Open access
Semantic Scholar

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D. J. Phillips — researcher profile on SciRah

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