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K. Morohashi · SciRah

Researcher profile · Semantic Scholar

K. Morohashi

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K. Morohashi — researcher profile on SciRah

h-index: 56
Works: 172
Citations: 11K

Most-cited papers

Foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with ad4 binding protein/steroidogenic factor 1.
De-Shou Wang, Tohru Kobayashi, Lin-Yan Zhou, B. Paul-Prasanth +5 more
2007Molecular Endocrinology489 citations
Semantic Scholar
Atrazine-Induced Aromatase Expression Is SF-1 Dependent: Implications for Endocrine Disruption in Wildlife and Reproductive Cancers in Humans
Wu-Qiang Fan, T. Yanase, Hidetaka Morinaga, Shigeki Gondo +7 more
2007Environmental Health Perspectives277 citations Open access
Semantic Scholar
Intrinsic Function of the Aryl Hydrocarbon (Dioxin) Receptor as a Key Factor in Female Reproduction
Takashi Baba, J. Mimura, Naohito Nakamura, N. Harada +3 more
2005Molecular and Cellular Biology252 citations Open access
Semantic Scholar
Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes.
Y. Shima, Kanako Miyabayashi, Shogo Haraguchi, Tatsuhiko Arakawa +8 more
2013Molecular Endocrinology236 citations Open access
Semantic Scholar
A critical time window of Sry action in gonadal sex determination in mice
R. Hiramatsu, S. Matoba, M. Kanai-Azuma, N. Tsunekawa +6 more
2009Development221 citations
Semantic Scholar
Generation of ovarian follicles from mouse pluripotent stem cells
Takashi Yoshino, Takahiro Suzuki, Go Nagamatsu, Haruka Yabukami +11 more
2021Science160 citations
Semantic Scholar
Corrigendum: Cxorf6 is a causative gene for hypospadias
M. Fukami, Y. Wada, Kanako Miyabayashi, I. Nishino +8 more
2007Nature Genetics144 citations Open access
Semantic Scholar
Two-Step Regulation of Ad4BP/SF-1 Gene Transcription during Fetal Adrenal Development: Initiation by a Hox-Pbx1-Prep1 Complex and Maintenance via Autoregulation by Ad4BP/SF-1
M. Zubair, S. Ishihara, Sanae Oka, K. Okumura +1 more
2006Molecular and Cellular Biology141 citations
Semantic Scholar
Cbx2, a polycomb group gene, is required for Sry gene expression in mice.
Y. Katoh-Fukui, Kanako Miyabayashi, T. Komatsu, A. Owaki +9 more
2012Endocrinology131 citations
Semantic Scholar
Developmental Links between the Fetal and Adult Zones of the Adrenal Cortex Revealed by Lineage Tracing
M. Zubair, K. Parker, K. Morohashi
2008Molecular and Cellular Biology122 citations Open access
Semantic Scholar
Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9.
T. Komatsu, H. Mizusaki, T. Mukai, Hidesato Ogawa +7 more
2004Molecular Endocrinology115 citations Open access
Semantic Scholar
Testicular dysgenesis without adrenal insufficiency in a 46,XY patient with a heterozygous inactive mutation of steroidogenic factor-1.
T. Hasegawa, M. Fukami, N. Sato, N. Katsumata +4 more
2004Journal of Clinical Endocrinology and Metabolism102 citations
Semantic Scholar
Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development.
Yuka Fujimoto, Satomi S. Tanaka, Yasuka L. Yamaguchi, Hiroki Kobayashi +7 more
2013Developmental Cell100 citations Open access
Semantic Scholar
Mechanism of asymmetric ovarian development in chick embryos
Yoshiyasu Ishimaru, T. Komatsu, M. Kasahara, Y. Katoh-Fukui +7 more
2008Development99 citations
Semantic Scholar
Mouse Polycomb M33 is required for splenic vascular and adrenal gland formation through regulating Ad4BP/SF1 expression.
Y. Katoh-Fukui, A. Owaki, Y. Toyama, Masatomo Kusaka +4 more
2005Blood97 citations Open access
Semantic Scholar
Loss of PGC-specific expression of the orphan nuclear receptor ERR-beta results in reduction of germ cell number in mouse embryos.
Kanae Mitsunaga, K. Araki, H. Mizusaki, K. Morohashi +5 more
2004Mechanisms of Development93 citations Open access
Semantic Scholar
PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.
T. Dumontet, I. Sahut-Barnola, A. Septier, N. Montanier +10 more
2018JCI Insight84 citations Open access
Semantic Scholar
Mastermind-like Domain-containing 1 (MAMLD1 or CXorf6) Transactivates the Hes3 Promoter, Augments Testosterone Production, and Contains the SF1 Target Sequence*
M. Fukami, Y. Wada, Michiyo Okada, Fumiko Kato +6 more
2008Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor (EGFR) expression induced in Emx2 KO embryonic gonads.
Masatomo Kusaka, Y. Katoh-Fukui, Hidesato Ogawa, Kanako Miyabayashi +12 more
2010Endocrinology80 citations Open access
Semantic Scholar
Aristaless Related Homeobox Gene, Arx, Is Implicated in Mouse Fetal Leydig Cell Differentiation Possibly through Expressing in the Progenitor Cells
Kanako Miyabayashi, Y. Katoh-Fukui, Hidesato Ogawa, Takashi Baba +4 more
2013PLoS ONE74 citations Open access
Semantic Scholar
Fetal Leydig Cells Persist as an Androgen-Independent Subpopulation in the Postnatal Testis.
Y. Shima, S. Matsuzaki, Kanako Miyabayashi, Hiroyuki Otake +4 more
2015Molecular Endocrinology67 citations Open access
Semantic Scholar
Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1
Takashi Baba, Hiroyuki Otake, Tetsuya Sato, Kanako Miyabayashi +15 more
2014Nature Communications63 citations Open access
Semantic Scholar
Transgenic expression of Ad4BP/SF-1 in fetal adrenal progenitor cells leads to ectopic adrenal formation.
M. Zubair, Sanae Oka, K. Parker, K. Morohashi
2009Molecular Endocrinology61 citations Open access
Semantic Scholar
DNA methylation of intronic enhancers directs tissue-specific expression of steroidogenic factor 1/adrenal 4 binding protein (SF-1/Ad4BP).
E. Hoivik, Trine E Bjanesoy, O. Mai, Shiki Okamoto +5 more
2011Endocrinology60 citations Open access
Semantic Scholar
Hypogonadotropic hypogonadism in an adult female with a heterozygous hypomorphic mutation of SOX2.
N. Sato, Y. Kamachi, H. Kondoh, Y. Shima +3 more
2007European Journal of Endocrinology55 citations Open access
Semantic Scholar
Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues
Maki Igarashi, K. Takasawa, Akiko Hakoda, Junko Kanno +12 more
2017Human Mutation54 citations Open access
Semantic Scholar
Identification of an enhancer in the Ad4BP/SF-1 gene specific for fetal Leydig cells.
Y. Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake +4 more
2012Endocrinology54 citations
Semantic Scholar
Leydig progenitor cells in fetal testis.
Y. Shima, K. Morohashi
2017Molecular and Cellular Endocrinology46 citations
Semantic Scholar
Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.
Miki Inoue, Y. Shima, Kanako Miyabayashi, K. Tokunaga +6 more
2016Endocrinology45 citations
Semantic Scholar
Ventromedial hypothalamic nucleus-specific enhancer of Ad4BP/SF-1 gene.
Y. Shima, M. Zubair, S. Ishihara, Y. Shinohara +6 more
2005Molecular Endocrinology45 citations
Semantic Scholar
Identification of Myelin Transcription Factor 1 (MyT1) as a Subunit of the Neural Cell Type-specific Lysine-specific Demethylase 1 (LSD1) Complex*
Atsushi Yokoyama, K. Igarashi, Tetsuya Sato, K. Takagi +8 more
2014Journal of Biological Chemistry43 citations Open access
Semantic Scholar
Differential gene dosage effects of Ad4BP/SF-1 on target tissue development.
Fatchiyah, M. Zubair, Y. Shima, Sanae Oka +3 more
2006Biochemical and Biophysical Research Communications - BBRC43 citations Open access
Semantic Scholar
SF-1 deficiency causes lipid accumulation in Leydig cells via suppression of STAR and CYP11A1
Megumi Hatano, T. Migita, T. Ohishi, Y. Shima +4 more
2016Endocrine41 citations
Semantic Scholar
Heterogeneity in sexual bipotentiality and plasticity of granulosa cells in developing mouse ovaries
Kyoko Harikae, Kento Miura, Mai Shinomura, S. Matoba +6 more
2013Journal of Cell Science39 citations Open access
Semantic Scholar
The fetal and adult adrenal cortex.
K. Morohashi, M. Zubair
2011Molecular and Cellular Endocrinology39 citations
Semantic Scholar
Pituitary homeobox 2 regulates adrenal4 binding protein/steroidogenic factor-1 gene transcription in the pituitary gonadotrope through interaction with the intronic enhancer.
Y. Shima, M. Zubair, T. Komatsu, Sanae Oka +5 more
2008Molecular Endocrinology39 citations Open access
Semantic Scholar
Heterogeneity of Ovarian Theca and Interstitial Gland Cells in Mice
Kanako Miyabayashi, K. Tokunaga, Hiroyuki Otake, Takashi Baba +2 more
2015PLoS ONE34 citations Open access
Semantic Scholar
Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos.
H. Yoshioka, Yoshiyasu Ishimaru, N. Sugiyama, N. Tsunekawa +3 more
2005Developmental Biology34 citations Open access
Semantic Scholar
Importance of forkhead transcription factor Fkhl18 for development of testicular vasculature
Yuko Sato, Takashi Baba, M. Zubair, Kanako Miyabayashi +8 more
2008Molecular Reproduction and Development31 citations
Semantic Scholar
Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development
Kanako Miyabayashi, Y. Shima, Miki Inoue, Tetsuya Sato +4 more
2016Sexual Development30 citations Open access
Semantic Scholar
Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development.
M. Miyado, Michiko Nakamura, K. Miyado, K. Morohashi +4 more
2012Endocrinology29 citations Open access
Semantic Scholar
Testicular dysgenesis/regression without campomelic dysplasia in patients carrying missense mutations and upstream deletion of SOX9
Y. Katoh-Fukui, Maki Igarashi, Keisuke Nagasaki, R. Horikawa +14 more
2015Molecular Genetics & Genomic Medicine28 citations Open access
Semantic Scholar
Recent progress in understanding the mechanisms of Leydig cell differentiation.
Miki Inoue, Takashi Baba, K. Morohashi
2018Molecular and Cellular Endocrinology26 citations
Semantic Scholar
Ad4BP/SF-1 regulates cholesterol synthesis to boost the production of steroids
Takashi Baba, Hiroyuki Otake, Miki Inoue, Tetsuya Sato +14 more
2018Communications Biology26 citations Open access
Semantic Scholar
Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated nuclear receptor Ad4BP/SF-1.
Hidesato Ogawa, T. Komatsu, Y. Hiraoka, K. Morohashi
2009Molecular Biology of the Cell26 citations Open access
Semantic Scholar
A novel isoform of Vinexin, Vinexin γ, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad
M. Matsuyama, H. Mizusaki, A. Shimono, T. Mukai +4 more
2005Genes to Cells25 citations Open access
Semantic Scholar
Nuclear structure-associated TIF2 recruits glucocorticoid receptor and its target DNA.
Hidesato Ogawa, Ruth T. Yu, T. Haraguchi, Y. Hiraoka +3 more
2004Biochemical and Biophysical Research Communications - BBRC25 citations
Semantic Scholar
Sex differences in metabolic pathways are regulated by Pfkfb3 and Pdk4 expression in rodent muscle
Antonius Christianto, Takashi Baba, Fumiya Takahashi, K. Inui +5 more
2021Communications Biology23 citations Open access
Semantic Scholar
Coordination of Multiple Cellular Processes by NR5A1/Nr5a1
K. Morohashi, Miki Inoue, Takashi Baba
2020Endocrinology and Metabolism23 citations Open access
Semantic Scholar
Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1
Ye-Wei Xing, K. Morohashi, H. Ingraham, G. Hammer
2017Development23 citations Open access
Semantic Scholar

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Takashi Baba×20
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Takashi Baba — researcher profile on SciRah
Y. Shima×19
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Y. Shima — researcher profile on SciRah
Kanako Miyabayashi×13
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Kanako Miyabayashi — researcher profile on SciRah
M. Zubair×10
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Hidesato Ogawa×8

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Miki Inoue — researcher profile on SciRah

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T. Ogata — researcher profile on SciRah

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Sanae Oka — researcher profile on SciRah