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Jani Saksi · SciRah

Researcher profile · Semantic Scholar

Jani Saksi

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Jani Saksi — researcher profile on SciRah

h-index: 16
Works: 37
Citations: 1,143

Most-cited papers

NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.
Scott B. Widenmaier, Nicole A Snyder, Truc B Nguyen, A. Arduini +5 more
2017Cell214 citations Open access
Semantic Scholar
Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses
K. Prentice, Jani Saksi, Gökhan S. Hotamışlıgil
2019Journal of Lipid Research158 citations Open access
Semantic Scholar
Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke
T. Sairanen, Rita Szepesi, M. Karjalainen-Lindsberg, Jani Saksi +2 more
2009Acta Neuropathologica116 citations Open access
Semantic Scholar
Cerebral Mast Cells Mediate Blood-Brain Barrier Disruption in Acute Experimental Ischemic Stroke Through Perivascular Gelatinase Activation
O. Mattila, D. Strbian, Jani Saksi, Tero O Pikkarainen +3 more
2011Stroke97 citations Open access
Semantic Scholar
A hormone complex of FABP4 and nucleoside kinases regulates islet function
K. Prentice, Jani Saksi, L. Robertson, G. Y. Lee +11 more
2021Nature78 citations Open access
Semantic Scholar
Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties.
S. Lehti, S. Nguyen, I. Belevich, H. Vihinen +13 more
2017American Journal of Pathology73 citations Open access
Semantic Scholar
Microarray Analysis Reveals Overexpression of CD163 and HO-1 in Symptomatic Carotid Plaques
P. Ijäs, K. Nuotio, Jani Saksi, L. Soinne +8 more
2007Arteriosclerosis, Thrombosis and Vascular Biology57 citations Open access
Semantic Scholar
Adipophilin Expression Is Increased in Symptomatic Carotid Atherosclerosis: Correlation With Red Blood Cells and Cholesterol Crystals
K. Nuotio, Pia M. Isoviita, Jani Saksi, P. Ijäs +8 more
2007Stroke48 citations Open access
Semantic Scholar
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events.
P. Ijäs, Jani Saksi, L. Soinne, J. Tuimala +7 more
2013Atherosclerosis42 citations
Semantic Scholar
CoQ imbalance drives reverse electron transport to disrupt liver metabolism
Renata L. S. Goncalves, Zeqiu B. Wang, Jillian K. Riveros, Güneş Parlakgül +11 more
2025Nature35 citations Open access
Semantic Scholar
Low-Expression Variant of Fatty Acid–Binding Protein 4 Favors Reduced Manifestations of Atherosclerotic Disease and Increased Plaque Stability
Jani Saksi, P. Ijäs, M. Mäyränpää, K. Nuotio +15 more
2014Circulation: Cardiovascular Genetics35 citations
Semantic Scholar
Gene expression differences between stroke-associated and asymptomatic carotid plaques
Jani Saksi, P. Ijäs, K. Nuotio, Riitta Sonninen +8 more
2011Journal of molecular medicine32 citations Open access
Semantic Scholar
Is coproporphyrin III a copper-acquisition compound in Paracoccus denitrificans?
Jani V. Anttila, Petri Heinonen, Timo Nenonen, A. Pino +7 more
2011Biochimica et Biophysica Acta30 citations Open access
Semantic Scholar
The Low-Expression Variant of FABP4 Is Associated With Cardiovascular Disease in Type 1 Diabetes
E. Dahlström, Jani Saksi, C. Forsblom, Nicoline Uglebjerg +8 more
2021Diabetes22 citations Open access
Semantic Scholar
An Imbalance Between CD36 and ABCA1 Protein Expression Favors Lipid Accumulation in Stroke-Prone Ulcerated Carotid Plaques
Pia M. Isoviita, K. Nuotio, Jani Saksi, R. Turunen +6 more
2010Stroke21 citations Open access
Semantic Scholar
Haptoglobin Hp2 Variant Promotes Premature Cardiovascular Death in Stroke Survivors
P. Ijäs, S. Melkas, Jani Saksi, A. Jula +7 more
2017Stroke17 citations Open access
Semantic Scholar
Evolution of Intracerebral Hemorrhage after Intravenous Tpa: Reversal of Harmful Effects with Mast Cell Stabilization
I. Marinković, O. Mattila, D. Strbian, A. Meretoja +6 more
2014Journal of Cerebral Blood Flow and Metabolism15 citations Open access
Semantic Scholar
Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques – Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2)
K. Nuotio, P. Ijäs, H. Heikkilä, S. Koskinen +12 more
2018Annals medicus14 citations Open access
Semantic Scholar
Life-Threatening Coronary Disease is Prevalent in Patients with Stenosing Carotid Artery Disease
K. Nuotio, L. Soinne, H. Hänninen, Jani Saksi +6 more
2015International Journal of Stroke13 citations
Semantic Scholar
Glutamine synthetase in human carotid plaque macrophages associates with features of plaque vulnerability: An immunohistological study.
P. Sorto, M. Mäyränpää, Jani Saksi, K. Nuotio +6 more
2022Atherosclerosis10 citations Open access
Semantic Scholar
Warfarin Treatment Is Associated to Increased Internal Carotid Artery Calcification
K. Nuotio, S. Koskinen, L. Mäkitie, J. Tuimala +13 more
2021Frontiers in Neurology10 citations Open access
Semantic Scholar
Endothelial Apoptosis Does Not Determine Symptom Status in Carotid Artery Disease
K. Nuotio, M. Mäyränpää, Jani Saksi, P. Ijäs +9 more
2006Cerebrovascular Diseases6 citations
Semantic Scholar
Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity
Renata L. S. Goncalves, Zeqiu B. Wang, Karen E. Inouye, G. Y. Lee +10 more
2023bioRxiv2 citations Open access
Semantic Scholar
26-A-18859-ACC LIVER-TARGETED ASO AGAINST ANGIOTENSINOGEN BLUNTS CORTICOSTEROID-INDUCED SYSTEMIC BLOOD PRESSURE INCREASES IN RATS: POTENTIAL IMPLICATIONS FOR AGT MODULATION IN ACUTE SEVERE HYPERTENSION
G. Geist, Jani Saksi, C. Zambataro, Hannah M Kleppe +5 more
2026JACC0 citations
Semantic Scholar
Transmembrane protein 176B (TMEM176B) as a potential statin target gene in carotid artery disease
H. Heikkila, Jani Saksi, P. Ijäs, K. Nuotio +7 more
2021Atherosclerosis0 citations
Semantic Scholar
Evidence for enhanced de novo lipogenesis and uncoupling of obesity from type 2 diabetes risk in the low-expression variant carriers of fatty acid-binding protein 4
Jani Saksi, P. Ijäs, A. Jula, H. Heikkilä +7 more
20160 citations
Semantic Scholar
Abstract TP158: Haptoglobin Hp2 Variant Associates With an Increased Risk of Ischemic Cardiovascular Death After First-ever Stroke
P. Ijäs, S. Melkas, Jani Saksi, A. Jula +6 more
2016Stroke0 citations
Semantic Scholar
Workflow for automated quantification of cerebromicrovascular gelatinase activity.
O. Mattila, Ville Rantanen, Jani Saksi, D. Strbian +3 more
2015Microvascular Research0 citations
Semantic Scholar
Stroke-Associated Carotid Atherosclerosis - A Role for FABP4 in Atheroma Vulnerability and Cardiometabolic Risk
Jani Saksi
20150 citations
Semantic Scholar
Long alleles of the heme oxygenase 1 (HMOX1) promotor polymorphism associate with ulcerative carotid plaque and future tromboembolic events
P. Ijäs, K. Nuotio, N. Lim, Jani Saksi +4 more
20150 citations
Semantic Scholar
The low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability
Jani Saksi, P. Ijäs, M. Mäyränpää, K. Nuotio +13 more
20140 citations
Semantic Scholar
The low-expression variant of fatty acid-binding protein 4 (FABP4) associates with asymptomatic carotid atherosclerosis
Jani Saksi, P. Ijäs, M. Mäyränpää, K. Nuotio +5 more
20140 citations
Semantic Scholar
Abstract 2646: Haptoglobin 2 Allele Associates with Symptomatic Carotid Stenosis and Major Cardiovascular Events
P. Ijäs, P. Luoma, Jani Saksi, J. Tuimala +6 more
2012Stroke0 citations
Semantic Scholar
PO19-567 SERUM ADIPONECTIN LEVELS ASSOCIATE WITH TISSUE-TYPE PLASMINOGEN ACTIVATOR ACTIVITY IN PATIENTS WITH ADVANCED CAROTID ATHEROSCLEROSIS
Jani Saksi, P. Ijäs, L. Soinne, R. Lassila +5 more
20070 citations
Semantic Scholar
Tu-P7:278 Gene expression in unstable atherosclerotic carotid artery plaques
Jani Saksi, P. Ijäs, K. Nuotio, M. Mäyränpää +3 more
20060 citations
Semantic Scholar
Overexpression of CD 163 and HO-1 in Symptomatic Carotid
O. Salonen, S. Sarna, J. Tuimala, P. Kovanen +5 more
20060 citations
Semantic Scholar
Mo-P2:216 Adidophilin expression in carotid atherosclerosis
Pia M. Isoviita, K. Nuotio, Jani Saksi, P. Ijäs +4 more
20060 citations
Semantic Scholar

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