Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Fagerholm · SciRah

Researcher profile · Semantic Scholar

S. Fagerholm

Share profile

S. Fagerholm — researcher profile on SciRah

h-index: 25
Works: 57
Citations: 3,466

Most-cited papers

Cell Adhesion Molecules and Their Roles and Regulation in the Immune and Tumor Microenvironment
Heidi Harjunpää, Marc Llort Asens, Carla Guenther, S. Fagerholm
2019Frontiers in Immunology633 citations Open access
Semantic Scholar
Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
Amy R. Cameron, V. Morrison, Daniel Levin, M. Mohan +12 more
2016Circulation Research617 citations Open access
Semantic Scholar
Regulation of integrin activity and signalling
C. Gahmberg, S. Fagerholm, Susanna M. Nurmi, T. Chavakis +2 more
2009Biochimica et Biophysica Acta235 citations Open access
Semantic Scholar
Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding.
H. Takala, Elisa M. Nurminen, Susanna M. Nurmi, M. Aatonen +6 more
2008Blood181 citations Open access
Semantic Scholar
Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency Disease
S. Fagerholm, Carla Guenther, Marc Llort Asens, T. Savinko +1 more
2019Frontiers in Immunology138 citations Open access
Semantic Scholar
alpha-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation.
S. Fagerholm, M. Varis, Michael Stefanidakis, Tiina J. Hilden +1 more
2006Blood123 citations
Semantic Scholar
Phosphorylation of the Cytoplasmic Domain of the Integrin CD18 Chain by Protein Kinase C Isoforms in Leukocytes*
S. Fagerholm, N. Morrice, C. Gahmberg, P. Cohen
2002Journal of Biological Chemistry121 citations Open access
Semantic Scholar
Leukocyte integrins and inflammation
C. Gahmberg, L. Valmu, S. Fagerholm, P. Kotovuori +3 more
1998Cellular and Molecular Life Sciences (CMLS)114 citations Open access
Semantic Scholar
Specific integrin α and β chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms
S. Fagerholm, Tiina J. Hilden, Susanna M. Nurmi, C. Gahmberg
2005Journal of Cell Biology108 citations Open access
Semantic Scholar
β2 Integrin Signaling Cascade in Neutrophils: More Than a Single Function
Panagiota Bouti, Steven D. S. Webbers, S. Fagerholm, R. Alon +3 more
2021Frontiers in Immunology88 citations Open access
Semantic Scholar
A Systemic Lupus Erythematosus-associated R77H Substitution in the CD11b Chain of the Mac-1 Integrin Compromises Leukocyte Adhesion and Phagocytosis*
M. MacPherson, H. S. Lek, A. Prescott, S. Fagerholm
2011Journal of Biological Chemistry88 citations Open access
Semantic Scholar
P marks the spot: site-specific integrin phosphorylation regulates molecular interactions.
S. Fagerholm, Tiina J. Hilden, C. Gahmberg
2004TIBS -Trends in Biochemical Sciences. Regular ed82 citations
Semantic Scholar
A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells
P. Cook, H. Owen, A. Deaton, J. Borger +21 more
2015Nature Communications72 citations Open access
Semantic Scholar
The β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo.
V. Morrison, M. MacPherson, T. Savinko, H. S. Lek +2 more
2013Blood72 citations Open access
Semantic Scholar
The CD11b-integrin (ITGAM) and systemic lupus erythematosus
S. Fagerholm, M. MacPherson, M. James, C. Sevier-Guy +1 more
2013Lupus69 citations
Semantic Scholar
Phosphorylation of the LFA-1 Integrin β2-Chain on Thr-758 Leads to Adhesion, Rac-1/Cdc42 Activation, and Stimulation of CD69 Expression in Human T Cells*
Susanna M. Nurmi, M. Autero, Anna K. Raunio, C. Gahmberg +1 more
2007Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Loss of beta2-integrin-mediated cytoskeletal linkage reprograms dendritic cells to a mature migratory phenotype
V. Morrison, Martyn J. James, Katarzyna M. Grzes, P. Cook +8 more
2014Nature Communications65 citations Open access
Semantic Scholar
Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins.
E. Choi, V. Orlova, S. Fagerholm, Susanna M. Nurmi +4 more
2008Blood60 citations Open access
Semantic Scholar
The cytoskeletal association of CD11/CD18 leukocyte integrins in phorbol ester‐activated cells correlates with CD18 phosphorylation
L. Valmu, S. Fagerholm, H. Suila, C. Gahmberg
1999European Journal of Immunology59 citations Open access
Semantic Scholar
Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms
S. Fagerholm, Tiina J. Hilden, Susanna M. Nurmi, C. Gahmberg
200557 citations
Semantic Scholar
Lck tyrosine kinase is important for activation of the CD11a/CD18‐integrins in human T lymphocytes
S. Fagerholm, Tiina J. Hilden, C. Gahmberg
2002European Journal of Immunology44 citations Open access
Semantic Scholar
A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells
Christian Gawden-Bone, M. A. West, V. Morrison, A. Edgar +6 more
2014Journal of Cell Science39 citations Open access
Semantic Scholar
Filamin A Is Required for Optimal T Cell Integrin-Mediated Force Transmission, Flow Adhesion, and T Cell Trafficking
T. Savinko, Carla Guenther, L. Uotila, Marc Llort Asens +3 more
2018Journal of Immunology35 citations Open access
Semantic Scholar
The Spontaneously Adhesive Leukocyte Function-associated Antigen-1 (LFA-1) Integrin in Effector T Cells Mediates Rapid Actin- and Calmodulin-dependent Adhesion Strengthening to Ligand under Shear Flow*
H. S. Lek, V. Morrison, Michael J. Conneely, Paul A. Campbell +5 more
2013Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Kindlin-3 in the immune system.
S. Fagerholm, H. S. Lek, V. Morrison
2014American Journal of Clinical and Experimental Immunology33 citations
Semantic Scholar
A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation
Carla Guenther, Imrul Faisal, L. Uotila, M. L. Asens +8 more
2019Frontiers in Immunology29 citations Open access
Semantic Scholar
Filamin A Regulates Neutrophil Adhesion, Production of Reactive Oxygen Species, and Neutrophil Extracellular Trap Release
L. Uotila, Carla Guenther, T. Savinko, Timo A. Lehti +1 more
2017Journal of Immunology25 citations Open access
Semantic Scholar
β2-Integrin Adhesion Regulates Dendritic Cell Epigenetic and Transcriptional Landscapes to Restrict Dendritic Cell Maturation and Tumor Rejection
Carla Guenther, Imrul Faisal, Manlio Fusciello, M. Sokolova +8 more
2021Cancer immunology research23 citations Open access
Semantic Scholar
Optimal T Cell Activation and B Cell Antibody Responses In Vivo Require the Interaction between Leukocyte Function–Associated Antigen-1 and Kindlin-3
V. Morrison, L. Uotila, Marc Llort Asens, T. Savinko +1 more
2015Journal of Immunology20 citations Open access
Semantic Scholar
An essential role for calmodulin in regulating human T cell aggregation
S. Fagerholm, A. Prescott, Philip R. Cohen, C. Gahmberg
2001FEBS Letters20 citations
Semantic Scholar
Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in preeclampsia: a genetic and functional study
A. Lokki, L. Teirilä, M. Triebwasser, E. Daly +12 more
2021BJOG: an International Journal of Obstetrics and Gynaecology19 citations Open access
Semantic Scholar
Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation
P. Meakin, V. Morrison, C. Sneddon, T. Savinko +6 more
2015PLoS ONE19 citations Open access
Semantic Scholar
Interfering with leukocyte integrin activation—a novel concept in the development of anti‐inflammatory drugs
Tiina J. Hilden, Susanna M. Nurmi, S. Fagerholm, C. Gahmberg
2006Annals medicus19 citations Open access
Semantic Scholar
Functional Beta2-Integrins Restrict Skin Inflammation In Vivo.
T. Savinko, V. Morrison, L. Uotila, C. H. J. Wolff +2 more
2015Journal of Investigative Dermatology18 citations Open access
Semantic Scholar
Caveolin-1 influences LFA-1 redistribution upon TCR stimulation in CD8 T cells
J. Borger, V. Morrison, A. Filby, Céline Garcia +4 more
2017Journal of Immunology16 citations Open access
Semantic Scholar
14‐3‐3 Proteins Bind Both Filamin and αLβ2 Integrin in Activated T Cells
Susanna M. Nurmi, C. Gahmberg, S. Fagerholm
2006Annals of the New York Academy of Sciences16 citations
Semantic Scholar
Filamin and filamin-binding proteins in integrin-regulation and adhesion. Focus on: "FilaminA is required for vimentin-mediated cell adhesion and spreading".
M. MacPherson, S. Fagerholm
2010American Journal of Physiology - Cell Physiology15 citations Open access
Semantic Scholar
Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting—Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases
Evelien G. G. Sprenkeler, Carla Guenther, Imrul Faisal, T. Kuijpers +1 more
2021Frontiers in Immunology14 citations Open access
Semantic Scholar
Leukocyte Beta2-Integrins; Genes and Disease
M. MacPherson, H. S. Lek, Morrison, S. Fagerholm
201314 citations Open access
Semantic Scholar
Integrins in Health and Disease.
S. Fagerholm
2022New England Journal of Medicine13 citations Open access
Semantic Scholar
Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues
Sharon A. Matthews, Hwee San Lek, V. Morrison, M. G. Mackenzie +3 more
2012European Journal of Immunology13 citations Open access
Semantic Scholar
Leukocyte Adhesion—an Integrated Molecular Process at the Leukocyte Plasma Membrane
C. Gahmberg, L. Valmu, A. Kotovuori, P. Kotovuori +6 more
1999Bioscience Reports12 citations
Semantic Scholar
Leukocyte adhesion--a fundamental process in leukocyte physiology.
C. Gahmberg, Leena Valmu, Tian Li, Pekka Kotovuori +4 more
1999Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas10 citations Open access
Semantic Scholar
Editorial: Leukocyte Trafficking in Homeostasis and Disease
J. Teixidó, A. Hidalgo, S. Fagerholm
2019Frontiers in Immunology6 citations Open access
Semantic Scholar
Activation of Leukocyte β2‐integrins
C. Gahmberg, S. Fagerholm
20023 citations
Semantic Scholar
Examining the Effect of Kindlin-3 Binding Site Mutation on LFA-1-ICAM-1 Bonds by Force Measuring Optical Tweezers
Craig M. McDonald, V. Morrison, D. Mcgloin, S. Fagerholm
2022Frontiers in Immunology2 citations Open access
Semantic Scholar
dispensable for T-cell activation in vivo kindlin-3 interaction is essential for T-cell homing but - 2 integrin β The
S. Fagerholm, V. Morrison, M. MacPherson, T. Savinko +2 more
20132 citations
Semantic Scholar
Activation of leukocyte beta2-integrins.
C. Gahmberg, S. Fagerholm
2002Vox Sanguinis2 citations
Semantic Scholar
extravasation in vivo integrin is pivotal for integrin activation to bind ICAMs and leukocyte -chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) α
S. Fagerholm, M. Varis, Michael Stefanidakis, Tiina J. Hilden +1 more
20131 citations
Semantic Scholar
This information is current as Neutrophil Extracellular Trap Release Production of Reactive Oxygen Species , and Filamin A Regulates Neutrophil Adhesion , Lehti and
L. Uotila, Carla Guenther, T. Savinko, Timo A. Lehti +1 more
20170 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

C. Gahmberg×20
Invite
C. Gahmberg — researcher profile on SciRah
V. Morrison×14
Invite
V. Morrison — researcher profile on SciRah
T. Savinko×12
Invite
T. Savinko — researcher profile on SciRah
L. Uotila×10
Invite
L. Uotila — researcher profile on SciRah

Tiina J. Hilden

×9

Invite

Tiina J. Hilden — researcher profile on SciRah

Carla Guenther×8

Invite

Carla Guenther — researcher profile on SciRah

Susanna M. Nurmi×8

Invite

Susanna M. Nurmi — researcher profile on SciRah

Invite

H. S. Lek — researcher profile on SciRah

M. MacPherson×6

Invite

M. MacPherson — researcher profile on SciRah

Invite

A. Prescott — researcher profile on SciRah

Heidi Harjunpää×3

Invite

Heidi Harjunpää — researcher profile on SciRah

Marc Llort Asens×3