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S. Bigner · SciRah

Researcher profile · Semantic Scholar

S. Bigner

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S. Bigner — researcher profile on SciRah

h-index: 60
Works: 197
Citations: 20K

Most-cited papers

PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
Jing Li, Clifford Yen, D. Liaw, K. Podsypanina +13 more
1997Science5,210 citations
Semantic Scholar
Structural alterations of the epidermal growth factor receptor gene in human gliomas.
A. Wong, J. Ruppert, S. Bigner, Carl H. Grzeschik +3 more
1992Proceedings of the National Academy of Sciences of the United States of America900 citations Open access
Semantic Scholar
Deletion of p16 and p15 genes in brain tumors.
J. Jen, J. Harper, S. Bigner, D. Bigner +5 more
1994Cancer Research467 citations
Semantic Scholar
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.
H. Friedman, R. McLendon, T. Kerby, M. Dugan +17 more
1998Journal of Clinical Oncology434 citations Open access
Semantic Scholar
PTEN gene mutations are seen in high-grade but not in low-grade gliomas.
B. A. Ahmed Rasheed, T. Stenzel, R. McLendon, R. Parsons +4 more
1997Cancer Research407 citations
Semantic Scholar
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
P. A. Humphrey, A. Wong, B. Vogelstein, M. Zalutsky +6 more
1990Proceedings of the National Academy of Sciences of the United States of America400 citations Open access
Semantic Scholar
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.
S. Bigner, P. Humphrey, A. Wong, B. Vogelstein +3 more
1990Cancer Research341 citations
Semantic Scholar
Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization.
S. Bigner, M. Matthews, B. Rasheed, R. Wiltshire +6 more
1999American Journal of Pathology274 citations Open access
Semantic Scholar
Alterations of the TP53 gene in human gliomas.
B. A. Ahmed Rasheed, R. McLendon, J. Herndon, H. Friedman +3 more
1994Cancer Research270 citations
Semantic Scholar
Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro.
Morten Lund-Johansen, R. Bjerkvig, P. A. Humphrey, S. Bigner +2 more
1990Cancer Research244 citations
Semantic Scholar
Molecular pathogenesis of malignant gliomas.
B. A. Ahmed Rasheed, R. Wiltshire, S. Bigner, D. Bigner
1999Current Opinion in Oncology228 citations
Semantic Scholar
Infrequent p53 gene mutations in medulloblastomas.
R. Saylors, D. Sidransky, H. Friedman, S. Bigner +3 more
1991Cancer Research213 citations
Semantic Scholar
Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.
B. Rasheed, R. McLendon, Henry S. Friedman, A. Friedman +3 more
1995Oncogene211 citations
Semantic Scholar
Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results.
D. Bigner, Mark T. Brown, A. Friedman, R. Coleman +14 more
1998Journal of Clinical Oncology201 citations
Semantic Scholar
MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group.
Naji Aldosari, S. Bigner, P. Burger, L. Becker +3 more
2002Archives of Pathology & Laboratory Medicine185 citations
Semantic Scholar
Cytogenetics and Molecular Genetics of Malignant Gliomas and Medulloblastoma
S. Bigner, B. Vogelstein
1990Brain Pathology161 citations Open access
Semantic Scholar
Multicenter Masked Evaluation of AutoCyte PREP Thin Layers with Matched Conventional Smears
John W. Bishop, S. Bigner, T. Colgan, M. Husain +4 more
1998Acta Cytologica141 citations
Semantic Scholar
Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft.
Henry S. Friedman, Stewart P. Johnson, Qing Dong, S. Schold +12 more
1997Cancer Research138 citations
Semantic Scholar
Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas.
I. Cokgor, G. Akabani, Chien-Tsun Kuan, Henry S. Friedman +13 more
2000Journal of Clinical Oncology137 citations
Semantic Scholar
Patterns of the early, gross chromosomal changes in malignant human gliomas.
S. Bigner, Joachim Mark, M. Mahaley, D. Bigner
2008Hereditas136 citations Open access
Semantic Scholar
Oncogene amplification in pediatric brain tumors.
J. Wasson, R. Saylors, P. Zeltzer, Henry S. Friedman +6 more
1990Cancer Research134 citations
Semantic Scholar
Chromosomal characteristics of childhood brain tumors.
S. Bigner, R. McLendon, H. Fuchs, P. E. McKeever +1 more
1997Cancer Genetics and Cytogenetics129 citations
Semantic Scholar
Loss of heterozygosity for 10q loci in human gliomas
B. A. Ahmed Rasheed, G. Fuller, A. Friedman, D. Bigner +1 more
1992Genes, Chromosomes and Cancer128 citations
Semantic Scholar
Amplified cellular oncogenes in neoplasms of the human central nervous system.
Gregory N. Fuller, S. Bigner
1992Mutation research123 citations
Semantic Scholar
Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study.
J. L. Slack, D. C. Arthur, D. Lawrence, K. Mrózek +9 more
1997Journal of Clinical Oncology114 citations
Semantic Scholar
Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results.
M. Brown, R. Coleman, A. Friedman, H. Friedman +15 more
1996Clinical Cancer Research100 citations
Semantic Scholar
Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.
Xuan-Min He, C. Wikstrand, H. Friedman, S. Bigner +3 more
1991Laboratory investigation; a journal of technical methods and pathology99 citations
Semantic Scholar
Prognostic implications of chromosome 17p deletions in human medulloblastomas
S. Batra, R. McLendon, J. Koo, Shobha Castelino‐Prabhu +5 more
2005Journal of Neuro-Oncology91 citations
Semantic Scholar
Identification and characterization of neogenin, a DCC-related gene
J. Meyerhardt, A. Look, S. Bigner, E. Fearon
1997Oncogene91 citations Open access
Semantic Scholar
Gliomas of the optic nerve: histological, immunohistochemical (MIB-1 and p53), and MRI analysis
T. Cummings, J. Provenzale, S. Hunter, A. Friedman +3 more
2000Acta Neuropathologica90 citations
Semantic Scholar
Phase I studies of treatment of malignant gliomas and neoplastic meningitis with131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab′)2-a preliminary report
D. Bigner, Mark T. Brown, R. E. Coleman, A. Friedman +8 more
2005Journal of Neuro-Oncology80 citations
Semantic Scholar
Morphologic and molecular genetic aspects of oligodendroglial neoplasms.
S. Bigner, B. A. Ahmed Rasheed, Rodney N. Wiltshire, R. McLendon
1999Neuro-Oncology64 citations Open access
Semantic Scholar
MYCC and MYCN Oncogene Amplification in Medulloblastoma
Naji Aldosari, S. Bigner, P. Burger, L. Becker +3 more
200961 citations
Semantic Scholar
Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA): Design of a Prospective, Multicenter Trial of Diagnostic Tests
N. Mturi, K. Alcock, J. Carter, C. Newton +72 more
2004Neuroepidemiology60 citations
Semantic Scholar
Glioma-associated Antigen Expression in Oligodendroglial Neoplasms: Tenascin and Epidermal Growth Factor Receptor
R. McLendon, C. Wikstrand, M. Matthews, Raid Al-Baradei +2 more
2000Journal of Histochemistry and Cytochemistry59 citations Open access
Semantic Scholar
Comparative genetic patterns of glioblastoma multiforme: potential diagnostic tool for tumor classification.
Rodney N. Wiltshire, B. A. Ahmed Rasheed, Henry S. Friedman, A. Friedman +1 more
2000Neuro-Oncology59 citations Open access
Semantic Scholar
Cerebrospinal Fluid (CSF) Cytology: Current Status and Diagnostic Applications
S. Bigner
1992Journal of Neuropathology and Experimental Neurology59 citations
Semantic Scholar
Molecular markers of prognosis in astrocytic tumors
A. Rasheed, James E. Herndon, T. Stenzel, Jacqueline G. M. Raetz +6 more
2002Cancer58 citations Open access
Semantic Scholar
Distribution and dosimetry of I-123-labeled monoclonal antibody 81C6 in patients with anaplastic glioma.
S. Schold, Michael R. Zalutsky, R. Coleman, M. Glantz +4 more
1993Investigative Radiology55 citations
Semantic Scholar
Microsatellite analysis of childhood brain tumors
H. Blaeker, B. A. Ahmed Rasheed, R. McLendon, H. Friedman +3 more
1996Genes, Chromosomes and Cancer54 citations
Semantic Scholar
DCC expression is altered by multiple mechanisms in brain tumours.
Bradley C. Ekstrand, T. Mansfield, S. Bigner, Eric R. Fearon
1995Oncogene49 citations
Semantic Scholar
Disialoganglioside GD2 in human neuroectodermal tumor cell lines and gliomas
D. Longee, C. Wikstrand, J. Mnsson, X. He +5 more
1991Acta Neuropathologica46 citations
Semantic Scholar
Consistency of Primary Brain Tumor Diagnoses and Codes in Cancer Surveillance Systems
Monette S. Castillo, F. Davis, T. Surawicz, J. Bruner +3 more
2004Neuroepidemiology45 citations
Semantic Scholar
Comparative genomic hybridization analysis of astrocytomas: prognostic and diagnostic implications.
R. Wiltshire, J. Herndon, A. Lloyd, H. Friedman +3 more
2004Journal of Molecular Diagnostics44 citations Open access
Semantic Scholar
Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft.
Naji Aldosari, R. Wiltshire, A. Dutra, E. Schrock +4 more
2002Neuro-Oncology44 citations Open access
Semantic Scholar
Oncogenes and anti-oncogenes in human central nervous system tumors.
S. Batra, B. Rasheed, S. Bigner, D. Bigner
1994Laboratory investigation; a journal of technical methods and pathology44 citations
Semantic Scholar
Neural cell adhesion molecule (CD56)-positive acute myelogenous leukemia and myelodysplastic and myeloproliferative syndromes.
K. Mann, C. de Castro, J. Liu, J. Moore +2 more
1997American Journal of Clinical Pathology43 citations Open access
Semantic Scholar
Evaluation of an automated technique for assessment of marrow engraftment after allogeneic bone marrow transplantation using a commercially available kit.
J. Nuckols, B. Rasheed, Ronald C. McGlennen, S. Bigner +1 more
2000American Journal of Clinical Pathology41 citations
Semantic Scholar
Occurrence of Lacto Series Gangliosides 3'-isoLM1 and 3',6'-isoLD1 in Human Gliomas in vitro and in vivo
C. Wikstrand, Xuan-Min He, G. Fuller, S. Bigner +3 more
1991Journal of Neuropathology and Experimental Neurology39 citations
Semantic Scholar
Lack of association of human polyomaviruses with human brain tumors
R. Arthur, S. Grossman, B. Ronnett, S. Bigner +2 more
2005Journal of Neuro-Oncology38 citations
Semantic Scholar

Frequent co-authors

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R. McLendon×20
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R. McLendon — researcher profile on SciRah
D. Bigner×20
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D. Bigner — researcher profile on SciRah
H. Friedman×17
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H. Friedman — researcher profile on SciRah
A. Friedman×12
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A. Friedman — researcher profile on SciRah

×8

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D. Bigner — researcher profile on SciRah

B. A. Ahmed Rasheed×8

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B. A. Ahmed Rasheed — researcher profile on SciRah

C. Wikstrand×8

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C. Wikstrand — researcher profile on SciRah

B. Vogelstein×7

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B. Vogelstein — researcher profile on SciRah

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T. Stenzel — researcher profile on SciRah

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G. Fuller — researcher profile on SciRah

R. Wiltshire×4

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R. Wiltshire — researcher profile on SciRah

Xiao-Guang Zhao×4

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Xiao-Guang Zhao — researcher profile on SciRah