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L. Ciudad · SciRah

Researcher profile · Semantic Scholar

L. Ciudad

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L. Ciudad — researcher profile on SciRah

h-index: 23
Works: 53
Citations: 1,521

Most-cited papers

Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.
L. Sánchez-Abarca, Silvia Gutierrez-Cosío, C. Santamaria, T. Caballero-Velázquez +12 more
2010Blood237 citations Open access
Semantic Scholar
Systemic RNAi of the cockroach vitellogenin receptor results in a phenotype similar to that of the Drosophila yolkless mutant
L. Ciudad, M. Piulachs, X. Belles
2006The FEBS Journal133 citations Open access
Semantic Scholar
Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition
Virginia C. Rodríguez-Cortez, L. Del Pino-Molina, J. Rodríguez-Ubreva, L. Ciudad +7 more
2015Nature Communications98 citations Open access
Semantic Scholar
Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis
C. Lorente-Sorolla, Antonio Garcia-Gomez, F. Català-Moll, V. Toledano +12 more
2019Genome Medicine84 citations Open access
Semantic Scholar
NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation
L. de la Rica, Antonio Garcia-Gomez, N. R. Comet, J. Rodríguez-Ubreva +7 more
2015Genome Biology84 citations Open access
Semantic Scholar
Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis
J. Rodríguez-Ubreva, Carlos de la Calle-Fabregat, Tian-Lu Li, L. Ciudad +11 more
2019Annals of the Rheumatic Diseases62 citations
Semantic Scholar
SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages
Tian-Lu Li, Antonio Garcia-Gomez, Octavio Morante-Palacios, L. Ciudad +5 more
2019Nucleic Acids Research61 citations Open access
Semantic Scholar
Conservation of fruitless’ role as master regulator of male courtship behaviour from cockroaches to flies
E. Clynen, L. Ciudad, X. Belles, M. Piulachs
2011Development, Genes and Evolution53 citations Open access
Semantic Scholar
Long-Range Epigenetic Silencing Associates with Deregulation of Ikaros Targets in Colorectal Cancer Cells
B. Javierre, J. Rodríguez-Ubreva, F. Al-Shahrour, Marina Corominas +11 more
2011Molecular Cancer Research51 citations Open access
Semantic Scholar
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease
Antonio Garcia-Gomez, Tian-Lu Li, Carlos de la Calle-Fabregat, J. Rodríguez-Ubreva +15 more
2021Nature Communications50 citations Open access
Semantic Scholar
Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells
Octavio Morante-Palacios, Gerard Godoy-Tena, Josep Calafell-Segura, L. Ciudad +3 more
2022Nucleic Acids Research46 citations Open access
Semantic Scholar
Vitamin D receptor, STAT3, and TET2 cooperate to establish tolerogenesis.
F. Català-Moll, A. G. Ferreté-Bonastre, Gerard Godoy-Tena, Octavio Morante-Palacios +7 more
2022Cell Reports45 citations Open access
Semantic Scholar
NF-κB and TET2 promote macrophage reprogramming in hypoxia that overrides the immunosuppressive effects of the tumor microenvironment
Carlos de la Calle-Fabregat, Josep Calafell-Segura, Margaux Gardet, G. Dunsmore +12 more
2024Science Advances44 citations Open access
Semantic Scholar
Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes
J. Rodríguez-Ubreva, L. Ciudad, D. Gómez-Cabrero, M. Parra +6 more
2011Nucleic Acids Research43 citations Open access
Semantic Scholar
Methylome and transcriptome profiling of giant cell arteritis monocytes reveals novel pathways involved in disease pathogenesis and molecular response to glucocorticoids
E. Estupiñán-Moreno, L. Ortiz-Fernández, Tian-Lu Li, J. Hernández-Rodríguez +9 more
2022Annals of the Rheumatic Diseases39 citations Open access
Semantic Scholar
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses
J. Rodríguez-Ubreva, A. Arutyunyan, M. Bonder, L. Del Pino-Molina +23 more
2022Nature Communications39 citations Open access
Semantic Scholar
C/EBPa-Mediated Activation of MicroRNAs 34a and 223 Inhibits Lef1 Expression To Achieve Efficient Reprogramming into Macrophages
J. Rodríguez-Ubreva, L. Ciudad, C. V. van Oevelen, M. Parra +2 more
2014Molecular and Cellular Biology37 citations Open access
Semantic Scholar
Epstein–Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation
Henar Hernando, A. Islam, J. Rodríguez-Ubreva, I. Forné +4 more
2013Nucleic Acids Research36 citations Open access
Semantic Scholar
Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells
Octavio Morante-Palacios, L. Ciudad, R. Micheroli, Carlos de la Calle-Fabregat +7 more
2021Nucleic Acids Research34 citations Open access
Semantic Scholar
Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci
Tian-Lu Li, L. Ortiz-Fernández, E. Andrés-León, L. Ciudad +6 more
2020Genome Medicine32 citations Open access
Semantic Scholar
Epigenetic alterations in autoimmune disease
E. Ballestar, B. Javierre, L. de la Rica, D. Gómez-Cabrero +8 more
2011Journal of Translational Medicine27 citations Open access
Semantic Scholar
Epilepsy progression is associated with cumulative DNA methylation changes in inflammatory genes.
R. Martins-Ferreira, B. Leal, J. Chaves, Tian-Lu Li +6 more
2021Progress in neurobiology26 citations
Semantic Scholar
Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines
Gerard Godoy-Tena, Anis Barmada, Octavio Morante-Palacios, Carlos de la Calle-Fabregat +10 more
2022Genome Medicine24 citations Open access
Semantic Scholar
Vitamin D Receptor, STAT3 and TET2 Cooperate to Establish Tolerogenesis
F. Català-Moll, A. G. Ferreté-Bonastre, Gerard Godoy-Tena, Octavio Morante-Palacios +7 more
2021Social Science Research Network22 citations Open access
Semantic Scholar
JAK2-STAT Epigenetically Regulates Tolerized Genes in Monocytes in the First Encounter With Gram-Negative Bacterial Endotoxins in Sepsis
Octavio Morante-Palacios, C. Lorente-Sorolla, L. Ciudad, Josep Calafell-Segura +8 more
2021Frontiers in Immunology19 citations Open access
Semantic Scholar
The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis
Carlos de la Calle-Fabregat, J. Rodríguez-Ubreva, L. Ciudad, J. Ramírez +12 more
2022JCI Insight18 citations Open access
Semantic Scholar
Epigenetic regulation of PRAME in acute myeloid leukemia is different compared to CD34+ cells from healthy donors: effect of 5-AZA treatment.
Silvia Gutierrez-Cosío, L. de la Rica, E. Ballestar, C. Santamaria +10 more
2012Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis17 citations
Semantic Scholar
Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy
R. Martins-Ferreira, B. Leal, J. Chaves, L. Ciudad +4 more
2022Clinical Epigenetics14 citations Open access
Semantic Scholar
Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites
Virginia C. Rodríguez-Cortez, Paloma Martinez-Redondo, F. Català-Moll, J. Rodríguez-Ubreva +11 more
2017Scientific Reports13 citations Open access
Semantic Scholar
Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction
F. Català-Moll, Anna G. Ferreté-Bonastre, Tian-Lu Li, D. Weichenhan +21 more
2019bioRxiv10 citations Open access
Semantic Scholar
COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation
J. Rodríguez-Ubreva, Josep Calafell-Segura, C. L. Calvillo, Baerbel Keller +14 more
2024Nature Communications8 citations Open access
Semantic Scholar
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection
Anis Barmada, Louis-François Handfield, Gerard Godoy-Tena, Carlos de la Calle-Fabregat +34 more
2023European Journal of Immunology7 citations Open access
Semantic Scholar
Purinergic exposure induces epigenomic and transcriptomic-mediated preconditioning resembling epilepsy-associated microglial states
R. Martins-Ferreira, Josep Calafell-Segura, João Chaves, L. Ciudad +4 more
2024iScience3 citations Open access
Semantic Scholar
Decoding CD4+ T cell transcriptome in giant cell arteritis: Novel pathways and altered cross-talk with monocytes.
E. Estupiñán-Moreno, J. Hernández-Rodríguez, Tianlu Li, L. Ciudad +9 more
2024Journal of Autoimmunity3 citations Open access
Semantic Scholar
Vitamin D receptor and STAT3 cooperate to establish TET2-mediated tolerogenesis
F. Català-Moll, Tian-Lu Li, L. Ciudad, J. Rodríguez-Ubreva +1 more
2020bioRxiv3 citations Open access
Semantic Scholar
Tinostamustine (EDO-S101), an Alkylating Deacetylase Inhibitor, Enhances the Efficacy of Daratumumab in Multiple Myeloma by Upregulation of CD38 and NKG2D Ligands
A. Díaz-Tejedor, J. Rodríguez-Ubreva, L. Ciudad, M. Lorenzo-Mohamed +11 more
2024International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
Vitamin C and thiamine for the treatment of refractory septic shock in surgical critically ill patients: a retrospective before-and-after study
A. Suárez-de-la-Rica, Bryant Croes, L. Ciudad, Irene Vallejo +3 more
2022Revista Espanola de Quimioterapia1 citations Open access
Semantic Scholar
DNA methylation screening suggests brain origin of cell-free DNA in epilepsy
R. Martins-Ferreira, B. Leal, J. Chaves, Carlos Fabregat +6 more
2021Journal of Neurological Sciences1 citations
Semantic Scholar
Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses
J. Rodríguez-Ubreva, A. Arutyunyan, M. Bonder, L. Del Pino-Molina +23 more
2021bioRxiv1 citations Open access
Semantic Scholar
Psoriatic arthritis monocyte DNA methylomes bridge joint and skin inflammatory pathways across rheumatoid arthritis and psoriasis.
Cristina Gómez-Pereira, A. G. Ferreté-Bonastre, A. B. Azuaga, Mónica Munera-Campos +10 more
2026Annals of the Rheumatic Diseases0 citations Open access
Semantic Scholar
Purinergic Preconditioning Induces Epigenomic and Transcriptomic Changes Resembling Epilepsy-associated Microglial States
R. Martins-Ferreira, Josep Calafell-Segura, J. Chaves, L. Ciudad +4 more
2023bioRxiv0 citations Open access
Semantic Scholar
POS0093 TRANSCRIPTOMIC AND METHYLOMIC PROFILING OF CD4+ T-CELLS IN GIANT CELL ARTERITIS WITH DIFFERENT DISEASE ACTIVITY
E. Estupiñán-Moreno, J. Hernández-Rodríguez, T. Li, L. Ciudad +9 more
2023Annals of the Rheumatic Diseases0 citations Open access
Semantic Scholar
Vitamin C triggers NF-κB-driven epigenomic reprogramming and enhanced immunogenic responses of dendritic cells
Octavio Morante-Palacios, Gerard Godoy-Tena, Josep Calafell-Segura, L. Ciudad +3 more
2022bioRxiv0 citations Open access
Semantic Scholar
MAFB surrogates the glucocorticoid receptor ability to induce tolerogenesis in dendritic cells
Octavio Morante-Palacios, L. Ciudad, R. Micheroli, Carlos de la Calle-Fabregat +7 more
2021bioRxiv0 citations Open access
Semantic Scholar
The JAK2-STAT pathway epigenetically regulates tolerized genes during the first encounter with bacterial antigens
C. Lorente-Sorolla, Octavio Morante-Palacios, Antonio Garcia-Gomez, L. Ciudad +7 more
2020bioRxiv0 citations Open access
Semantic Scholar
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease
Antonio Garcia-Gomez, Tian-Lu Li, J. Rodríguez-Ubreva, L. Ciudad +11 more
2019bioRxiv0 citations Open access
Semantic Scholar
NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation
L. de la Rica, Antonio Garcia-Gomez, N. R. Comet, J. Rodríguez-Ubreva +7 more
2015Genome Biology0 citations Open access
Semantic Scholar
Macrophages Achieve Efficient Reprogramming into 34 a and 223 Inhibits Lef 1 Expression To C / EBPa-Mediated Activation of MicroRNAs
M. Parra, T. Graf, E. Ballestar, J. Rodríguez-Ubreva +2 more
20140 citations
Semantic Scholar
MacrophagesEfficient Reprogramming into 34a and 223 Inhibits Lef1 Expression To C/EBPa-Mediated Activation of MicroRNAs
M. Parra, T. Graf, E. Ballestar, J. Rodríguez-Ubreva +2 more
20140 citations
Semantic Scholar
Effect of Demethylating Agents (5-Azacytidine/5-AzaC) On the Immune Response
Silvia Gutiérrez Cosío, E. Ballestar, C. Santamaria, B. Blanco +8 more
20100 citations
Semantic Scholar

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