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O. Cazzalini · SciRah

Researcher profile · Semantic Scholar

O. Cazzalini

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O. Cazzalini — researcher profile on SciRah

h-index: 23
Works: 59
Citations: 2,961

Most-cited papers

Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin
Hana Koutnikova, V. Campuzano, F. Foury, P. Dollé +2 more
1997Nature Genetics478 citations
Semantic Scholar
Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response.
O. Cazzalini, A. Scovassi, M. Savio, L. Stivala +1 more
2010Mutation research442 citations
Semantic Scholar
Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria
F. Foury, O. Cazzalini
1997FEBS Letters385 citations
Semantic Scholar
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines.
M. C. Lazzé, M. Savio, R. Pizzala, O. Cazzalini +4 more
2004Carcinogenesis218 citations Open access
Semantic Scholar
Biology of the cell cycle inhibitor p21CDKN1A: molecular mechanisms and relevance in chemical toxicology
Ilaria Dutto, M. Tillhon, O. Cazzalini, L. Stivala +1 more
2014Archives of Toxicology208 citations
Semantic Scholar
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis
O. Cazzalini, S. Sommatis, M. Tillhon, Ilaria Dutto +8 more
2014Nucleic Acids Research103 citations Open access
Semantic Scholar
Anthocyanidins decrease endothelin-1 production and increase endothelial nitric oxide synthase in human endothelial cells.
M. C. Lazzé, R. Pizzala, Paola Perucca, O. Cazzalini +4 more
2006Molecular Nutrition & Food Research93 citations Open access
Semantic Scholar
Loss of p21CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence
Paola Perucca, O. Cazzalini, Mark A. Madine, M. Savio +4 more
2009Cell Cycle73 citations Open access
Semantic Scholar
p21CDKN1A Does Not Interfere with Loading of PCNA at DNA Replication Sites, but Inhibits Subsequent Binding of DNA Polymerase D at the G1/S Phase Transition
O. Cazzalini, Paola Perucca, F. Riva, L. Stivala +4 more
2003Cell Cycle69 citations Open access
Semantic Scholar
Revisiting the Function of p21CDKN1A in DNA Repair: The Influence of Protein Interactions and Stability
Giulio Ticli, O. Cazzalini, L. Stivala, E. Prosperi
2022International Journal of Molecular Sciences66 citations Open access
Semantic Scholar
The cyclin-dependent kinase inhibitor p21CDKN1A as a target of anti-cancer drugs.
L. Stivala, O. Cazzalini, E. Prosperi
2012Current Cancer Drug Targets64 citations
Semantic Scholar
Zidovudine-induced experimental myopathy: dual mechanism of mitochondrial damage.
A. Masini, C. Scotti, A. Calligaro, O. Cazzalini +7 more
1999Journal of Neurological Sciences63 citations Open access
Semantic Scholar
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen
Paola Perucca, O. Cazzalini, O. Mortusewicz, D. Necchi +6 more
2006Journal of Cell Science61 citations Open access
Semantic Scholar
p21waf1/cip1-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites
L. Stivala, F. Riva, O. Cazzalini, M. Savio +1 more
2001Oncogene61 citations Open access
Semantic Scholar
Effect of β-carotene on cell cycle progression of human fibroblasts
L. Stivala, M. Savio, O. Cazzalini, R. Pizzala +4 more
199661 citations Open access
Semantic Scholar
Interaction of p21CDKN1A with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair
O. Cazzalini, Paola Perucca, M. Savio, D. Necchi +5 more
2008Nucleic Acids Research57 citations Open access
Semantic Scholar
p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.
O. Cazzalini, F. Donà, M. Savio, M. Tillhon +5 more
2010DNA Repair56 citations
Semantic Scholar
Early effects of AZT on mitochondrial functions in the absence of mitochondrial DNA depletion in rat myotubes.
O. Cazzalini, M. C. Lazzé, Luisa Iamele, L. Stivala +8 more
2001Biochemical Pharmacology49 citations Open access
Semantic Scholar
p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG.
M. Tillhon, O. Cazzalini, T. Nardò, D. Necchi +4 more
2012DNA Repair42 citations
Semantic Scholar
The antiproliferative effect of β‐carotene requires p21waf1/cip1 in normal human fibroblasts
L. Stivala, M. Savio, S. Quarta, C. Scotti +8 more
200041 citations
Semantic Scholar
Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.
F. Riva, M. Savio, O. Cazzalini, L. Stivala +4 more
2004Experimental Cell Research32 citations
Semantic Scholar
Structure-activity relationship and role of oxygen in the potential antitumour activity of fluoroquinolones in human epithelial cancer cells.
Paola Perucca, M. Savio, O. Cazzalini, R. Mocchi +8 more
2014Journal of Photochemistry and Photobiology. B: Biology27 citations
Semantic Scholar
DDB2 association with PCNA is required for its degradation after UV-induced DNA damage
O. Cazzalini, Paola Perucca, R. Mocchi, S. Sommatis +2 more
2014Cell Cycle25 citations Open access
Semantic Scholar
Structure–Activity Relationship of Resveratrol and Its Analogue, 4,4′-Dihydroxy-Trans-Stilbene, Toward the Endothelin Axis in Human Endothelial Cells
T. Coppa, M. C. Lazzé, O. Cazzalini, Paola Perucca +7 more
2011Journal of Medicinal Food22 citations
Semantic Scholar
Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.
M. Savio, T. Coppa, O. Cazzalini, Paola Perucca +4 more
2009DNA Repair19 citations
Semantic Scholar
Mutations in CREBBP and EP300 genes affect DNA repair of oxidative damage in Rubinstein-Taybi syndrome cells.
Ilaria Dutto, Claudia Scalera, M. Tillhon, Giulio Ticli +7 more
2020Carcinogenesis17 citations
Semantic Scholar
Intracellular localization of the cyclin-dependent kinase inhibitor p21CDKN1A-GFP fusion protein during cell cycle arrest
O. Cazzalini, Paola Perucca, F. Valsecchi, L. Stivala +3 more
2004Histochemistry and Cell Biology15 citations
Semantic Scholar
Replication-Dependent DNA Damage Response Triggered by Roscovitine Induces an Uncoupling of DNA Replication Proteins
M. Savio, M. Cerri, O. Cazzalini, Paola Perucca +5 more
2006Cell Cycle14 citations Open access
Semantic Scholar
A damaged DNA binding protein 2 mutation disrupting interaction with proliferating-cell nuclear antigen affects DNA repair and confers proliferation advantage.
Paola Perucca, R. Mocchi, I. Guardamagna, E. Bassi +5 more
2018Biochimica et biophysica acta. Molecular cell research12 citations Open access
Semantic Scholar
p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates
Ilaria Dutto, M. Sukhanova, M. Tillhon, O. Cazzalini +4 more
2016PLoS ONE9 citations Open access
Semantic Scholar
p21CDKN1A and DNA Repair Systems: Recent Findings and Future Perspectives
M. Tillhon, O. Cazzalini, Ilaria Dutto, L. Stivala +1 more
20139 citations Open access
Semantic Scholar
The antiproliferative effect of beta-carotene requires p21waf1/cip1 in normal human fibroblasts.
L. Stivala, M. Savio, S. Quarta, C. Scotti +8 more
2000European Journal of Biochemistry9 citations
Semantic Scholar
Single Cell Determination of 7,8-dihydro-8-oxo-2′-deoxyguanosine by Fluorescence Techniques: Antibody vs. Avidin Labeling
Giusy Maraventano, Giulio Ticli, O. Cazzalini, L. Stivala +3 more
2023Molecules8 citations Open access
Semantic Scholar
A DDB2 mutant protein unable to interact with PCNA promotes cell cycle progression of human transformed embryonic kidney cells
Paola Perucca, S. Sommatis, R. Mocchi, E. Prosperi +2 more
2015Cell Cycle8 citations Open access
Semantic Scholar
Interaction of p 21 CDKN 1 A with PCNA regulates the histone acetyltransferase activity of p 300 in nucleotide excision repair
O. Cazzalini, Paola Perucca, M. Savio, D. Necchi +5 more
20088 citations
Semantic Scholar
Epithelial-to-mesenchymal transition and NF-kB pathways are promoted by a mutant form of DDB2, unable to bind PCNA, in UV-damaged human cells
Paola Perucca, E. Bassi, Martina Vetrò, Anna Tricarico +3 more
2024BMC Cancer7 citations Open access
Semantic Scholar
An improved method for the detection of nucleotide excision repair factors at local UV DNA damage sites.
Ilaria Dutto, O. Cazzalini, L. Stivala, E. Prosperi
2017DNA Repair6 citations
Semantic Scholar
A proteasome-dependent inhibition of SIRT-1 by the resveratrol analogue 4,4′-dihydroxy-trans-stilbene
Vittoria Livraghi, Laura Mazza, F. Chiappori, Miriana Cardano +7 more
2024Journal of Traditional and Complementary Medicine5 citations Open access
Semantic Scholar
Transcriptional Stress Induces Chromatin Relocation of the Nucleotide Excision Repair Factor XPG
Claudia Scalera, Giulio Ticli, Ilaria Dutto, O. Cazzalini +2 more
2021International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Differential effect of asparagine and glutamine removal on three adenocarcinoma cell lines
G. Pessino, L. Lonati, C. Scotti, Silvia Calandra +13 more
2024Heliyon3 citations
Semantic Scholar
Exploring new potential role of DDB2 by host cell reactivation assay in human tumorigenic cells
E. Bassi, Paola Perucca, I. Guardamagna, E. Prosperi +2 more
2019BMC Cancer3 citations Open access
Semantic Scholar
histone acetyltransferase activity of p300 in nucleotide excision repair
O. Cazzalini, Paola Perucca, M. Savio, D. Necchi +5 more
20083 citations
Semantic Scholar
Lack of molecular relationships between lipid peroxidation and mitochondrial DNA single strand breaks in isolated rat hepatocytes and mitochondria.
C. Scotti, Luisa Iamele, A. Alessandrini, V. Vannini +9 more
2003Mitochondrion (Amsterdam. Print)3 citations Open access
Semantic Scholar
A functional in vitro cell-free system for studying DNA repair in isolated nuclei
I. Guardamagna, E. Bassi, M. Savio, Paola Perucca +3 more
2020Journal of Cell Science2 citations Open access
Semantic Scholar
Epigenetic remodeling during UV exposure: high resolution analysis of histone post-translational modifications in a DNA binding protein 2 mutant model
C. Casali, Margherita Cavallo, Adel Diaf, Davide Tunesi +6 more
2026Histochemistry and Cell Biology1 citations Open access
Semantic Scholar
recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen
Paola Perucca, O. Cazzalini, O. Mortusewicz, D. Necchi +6 more
20061 citations
Semantic Scholar
Temporal and spatial patterns of γH2AX signaling in different human cells after exposure to X-rays and UV-C light
I. Guardamagna, L. Lonati, O. Iaria, A. Mentana +11 more
2026Radiation and Environmental Biophysics0 citations Open access
Semantic Scholar
Stability of c-Myc Protein in Early S Phase Is Regulated by the Interaction with PCNA
Miriana Cardano, O. Cazzalini, Giusy Maraventano, L. Stivala +2 more
2026International Journal of Molecular Sciences0 citations Open access
Semantic Scholar
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh +3 more
2026FEBS Open Bio0 citations Open access
Semantic Scholar
Expression of Concern: Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen.
Paola Perucca, O. Cazzalini, O. Mortusewicz, D. Necchi +6 more
2022Journal of Cell Science0 citations Open access
Semantic Scholar

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