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K. Heinzmann · SciRah

Researcher profile · Semantic Scholar

K. Heinzmann

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K. Heinzmann — researcher profile on SciRah

h-index: 11
Works: 26
Citations: 689

Most-cited papers

A Phase I Dose-Escalation Study of AZD3965, an Oral Monocarboxylate Transporter 1 Inhibitor, in Patients with Advanced Cancer
S. Halford, G. Veal, S. Wedge, G. Payne +17 more
2023Clinical Cancer Research256 citations Open access
Semantic Scholar
Multiplexed imaging for diagnosis and therapy
K. Heinzmann, L. Carter, J. Lewis, E. Aboagye
2017Nature Biomedical Engineering134 citations
Semantic Scholar
AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
T. Yap, M. Walton, Kyla M. Grimshaw, R. Te Poele +18 more
2012Clinical Cancer Research78 citations
Semantic Scholar
Preclinical Applications of 3'-Deoxy-3'-[18F]Fluorothymidine in Oncology - A Systematic Review
S. Schelhaas, K. Heinzmann, V. Bollineni, G. M. Kramer +6 more
2017Theranostics40 citations Open access
Semantic Scholar
Phase I expansion study of the first-in-class monocarboxylate transporter 1 (MCT1) inhibitor AZD3965 in patients with diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL).
S. Halford, H. Walter, P. McKay, W. Townsend +11 more
202132 citations Open access
Semantic Scholar
Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer
S. Dubash, S. Merchant, K. Heinzmann, F. Mauri +13 more
2018European Journal of Nuclear Medicine and Molecular Imaging29 citations Open access
Semantic Scholar
Variability of Proliferation and Diffusion in Different Lung Cancer Models as Measured by 3′-Deoxy-3′-18F-Fluorothymidine PET and Diffusion-Weighted MR Imaging
S. Schelhaas, L. Wachsmuth, T. Viel, D. Honess +14 more
2014Journal of Nuclear Medicine26 citations Open access
Semantic Scholar
Tracing Nutrient Flux Following Monocarboxylate Transporter-1 Inhibition with AZD3965
Marta Braga, Maciej A. Kaliszczak, L. Carroll, Z. Schug +13 more
2020Cancers20 citations Open access
Semantic Scholar
Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3'-Deoxy-3'-[18F]Fluorothymidine in Preclinical Models of Lung Cancer.
S. Schelhaas, A. Held, L. Wachsmuth, S. Hermann +6 more
2016Cancer Research18 citations Open access
Semantic Scholar
The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models
K. Heinzmann, D. Honess, D. Lewis, Donna M. Smith +11 more
2016EJNMMI Research13 citations Open access
Semantic Scholar
Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using 18F-ICMT-11 and 18F-FLT PET
K. Heinzmann, Q. Nguyen, D. Honess, Donna M. Smith +5 more
2018Journal of Nuclear Medicine11 citations Open access
Semantic Scholar
Evaluation of apoptosis imaging biomarkers in a genetic model of cell death
V. Vassileva, S. Stribbling, Chris P. Barnes, L. Carroll +10 more
2019EJNMMI Research10 citations Open access
Semantic Scholar
Thymidine Metabolism as a Confounding Factor for 3′-Deoxy-3′-18F-Fluorothymidine Uptake After Therapy in a Colorectal Cancer Model
S. Schelhaas, L. Wachsmuth, S. Hermann, Natascha Rieder +15 more
2018Journal of Nuclear Medicine7 citations Open access
Semantic Scholar
Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics
Yunqing Li, M. Inglese, S. Dubash, Chris P. Barnes +11 more
2021Pharmaceutics6 citations Open access
Semantic Scholar
3′-Deoxy-3′-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models
S. Schelhaas, K. Heinzmann, D. Honess, Donna M. Smith +8 more
2018Molecular Imaging and Biology6 citations
Semantic Scholar
Response Monitoring with [18F]FLT PET and Diffusion-Weighted MRI After Cytotoxic 5-FU Treatment in an Experimental Rat Model for Colorectal Liver Metastases
S. Heskamp, L. Heijmen, Danny Gerrits, J. Molkenboer-Kuenen +11 more
2016Molecular Imaging and Biology6 citations Open access
Semantic Scholar
Abstract 928: The novel clinical candidate AT13148 is an oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity and demonstrates a mechanism of action distinct from AKT inhibitors
T. Yap, M. Walton, Kyla M. Grimshaw, R. T. Poele +18 more
20122 citations
Semantic Scholar
Correction: AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity.
T. Yap, M. Walton, Kyla M. Grimshaw, R. Te Poele +18 more
2025Clinical Cancer Research1 citations
Semantic Scholar
EP-2102: Correlating MRI radiomics with biology during therapy in cancer models: a tool for drug development?
H. Woodruff, F. Blé, A. Jochens, R. Leijenaar +5 more
20181 citations Open access
Semantic Scholar
Cancer Therapy : Preclinical AT 13148 Is a Novel , Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
T. Yap, M. Walton, Kyla M. Grimshaw, R. Te Poele +18 more
20121 citations
Semantic Scholar
CRUK: Phase II trial of ginisortamab with (1) 1st-line gemcitabine + nab-paclitaxel (AG) or (2) MEK inhibitor as maintenance therapy in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC).
T. R. Jeffry Evans, T. Guren, Mark Baxter, Alan Christie +16 more
2026Journal of Clinical Oncology0 citations Open access
Semantic Scholar
Supplementary Material: Tracing Nutrient Flux Following Monocarboxylate Transporter-1 Inhibition with AZD3965
Marta Braga, Maciej A. Kaliszczak, L. Carroll, Z. Schug +12 more
20200 citations
Semantic Scholar
Depicting changes in tumor biology in response to cetuximab mono- or combination therapy by apoptosis and proliferation imaging using 18 F-ICMT-11 and 3’-Deoxy-3’-[
K. Heinzmann, Q. Nguyen, D. Honess, Donna M. Smith +5 more
20180 citations
Semantic Scholar
Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models
K. Heinzmann, D. Honess, D. Lewis, Donna M. Smith +11 more
2017EJNMMI Research0 citations Open access
Semantic Scholar
Diffusion-Weighted MR 18-′-Deoxy-3 ′ Measured by 3 Variability of Proliferation and Diffusion in Different Lung Cancer Models as
S. Schelhaas, L. Wachsmuth, T. Viel, D. Honess +14 more
20140 citations
Semantic Scholar
Structure of PKA-PKB chimera complexed with (1S)-2-amino-1-(4- chlorophenyl)-1-(4-(1H-pyrazol-4-yl)phenyl)ethan-1-ol
T. G. Davies, T. Yap, M. Walton, Kyla M. Grimshaw +18 more
20120 citations
Semantic Scholar

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