Leire Aguinagalde

Most-cited papers

1. Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria

   Stian Foss, S. A. Sakya, Leire Aguinagalde, M. Lustig +21 more

   2024Nature Communications69 citations Open access

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2. Auranofin efficacy against MDR Streptococcus pneumoniae and Staphylococcus aureus infections.

   Leire Aguinagalde, Roberto Díez-Martínez, J. Yuste, Inmaculada Royo +9 more

   2015Journal of Antimicrobial Chemotherapy64 citations Open access

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3. Emergence of Amoxicillin-Resistant Variants of Spain9V-ST156 Pneumococci Expressing Serotype 11A Correlates with Their Ability to Evade the Host Immune Response

   Leire Aguinagalde, B. Corsini, A. Domenech, Mirian Domenech +6 more

   2015PLoS ONE45 citations Open access

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4. Chemotherapy with Phage Lysins Reduces Pneumococcal Colonization of the Respiratory Tract

   B. Corsini, Roberto Díez-Martínez, Leire Aguinagalde, F. González-Camacho +4 more

   2018Antimicrobial Agents and Chemotherapy24 citations Open access

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5. Immunization with LytB protein of Streptococcus pneumoniae activates complement-mediated phagocytosis and induces protection against pneumonia and sepsis.

   B. Corsini, Leire Aguinagalde, Susana Ruiz, Mirian Domenech +5 more

   2016Vaccine22 citations Open access

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6. Development of synthetic, self-adjuvanting, and self-assembling anticancer vaccines based on a minimal saponin adjuvant and the tumor-associated MUC1 antigen

   Carlo Pifferi, Leire Aguinagalde, Ane Ruiz‐de‐Angulo, Nagore Sacristán +5 more

   2023Chemical Science13 citations Open access

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7. Novel Oxime-Derivatized Synthetic Triterpene Glycosides as Potent Saponin Vaccine Adjuvants

   Roberto Fuentes, Leire Aguinagalde, Carlo Pifferi, Adrián Plata +4 more

   2022Frontiers in Immunology11 citations Open access

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8. Vaccination with LytA, LytC, or Pce of Streptococcus pneumoniae Protects against Sepsis by Inducing IgGs That Activate the Complement System

   B. Corsini, Leire Aguinagalde, Susana Ruiz, Mirian Domenech +1 more

   2021Vaccines7 citations Open access

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9. Design, synthesis, and initial immunological evaluation of glycoconjugates based on saponin adjuvants and the Tn antigen

   Roberto Fuentes, Leire Aguinagalde, Nagore Sacristán, Alberto Fernández-Tejada

   2021Chemical Communications4 citations Open access

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10. Synthesis and In Vivo Immunological Evaluation of Novel Saponin-Antigen Conjugates Incorporating Tumor-Associated Carbohydrate and Peptide Epitopes.

    Roberto Fuentes, Priscila Tonon-Baschirotto, Leire Aguinagalde, Alberto Fernández-Tejada

    2026Chemistry0 citations Open access

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11. Design, synthesis and immunological evaluation of CRM197-based immunogens functionalized with synthetic scaffolds displaying a tumor-associated MUC1 glycopeptide.

    Carlo Pifferi, D. Goyard, Leire Aguinagalde, O. Renaudet +2 more

    2025Biomaterials Science0 citations

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12. Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune 1 protection against Streptococcus pneumoniae 2

    Leire Aguinagalde, M. A. den Boer, Suzanne M. Castenmiller, S. Zwarthoff +7 more

    20220 citations

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