G. Appel

Most-cited papers

Diagnostic Utility of Exome Sequencing for Kidney Disease
E. Groopman, M. Marasà, Sophia R. Cameron-Christie, S. Petrovski +48 more
2018New England Journal of Medicine702 citations Open access
Semantic Scholar
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference.
T. Goodship, H. Cook, F. Fakhouri, F. Fervenza +49 more
2017Kidney International648 citations Open access
Semantic Scholar
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
K. Kiryluk, Yifu Li, F. Scolari, S. Sanna-Cherchi +88 more
2014Nature Genetics602 citations Open access
Semantic Scholar
C3 GLOMERULOPATHY: CONSENSUS REPORT
M. Pickering, V. D'Agati, C. Nester, Richard J. H. Smith +31 more
2013Kidney International594 citations Open access
Semantic Scholar
Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy.
F. Fervenza, G. Appel, S. Barbour, B. Rovin +34 more
2019New England Journal of Medicine522 citations Open access
Semantic Scholar
C3 glomerulopathy — understanding a rare complement-driven renal disease
Richard J. H. Smith, G. Appel, A. Blom, H. Cook +14 more
2019Nature Reviews Nephrology364 citations Open access
Semantic Scholar
Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multi-disciplinary approach
C. Gadegbeku, D. Gipson, L. Holzman, A. Ojo +36 more
2013Kidney International335 citations Open access
Semantic Scholar
New developments in the genetics, pathogenesis, and therapy of IgA nephropathy
R. Magistroni, V. D'Agati, G. Appel, Krzysztof Kiryluk
2015Kidney International288 citations Open access
Semantic Scholar
Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN.
S. Sethi, M. Haas, G. Markowitz, V. D'Agati +31 more
2016Journal of the American Society of Nephrology274 citations Open access
Semantic Scholar
A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction.
R. Lafayette, P. Canetta, B. Rovin, G. Appel +14 more
2017Journal of the American Society of Nephrology263 citations Open access
Semantic Scholar
A proposal for standardized grading of chronic changes in native kidney biopsy specimens.
S. Sethi, V. D'Agati, C. Nast, A. Fogo +23 more
2017Kidney International258 citations Open access
Semantic Scholar
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis
Jingyuan Xie, Li-Li Liu, N. Mladkova, Yifu Li +116 more
2020Nature Communications193 citations Open access
Semantic Scholar
Toward a working definition of C3 glomerulopathy by immunofluorescence.
Jean Hou, G. Markowitz, A. Bomback, G. Appel +3 more
2014Kidney International187 citations Open access
Semantic Scholar
C3 glomerulonephritis and dense deposit disease share a similar disease course in a large United States cohort of patients with C3 glomerulopathy.
A. Bomback, D. Santoriello, Rupali S. Avasare, Renu Regunathan-Shenk +9 more
2018Kidney International185 citations Open access
Semantic Scholar
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy
K. Kiryluk, Elena Sanchez-Rodriguez, Xu-Jie Zhou, Francesca Zanoni +184 more
2023Nature Genetics178 citations Open access
Semantic Scholar
Pathology after eculizumab in dense deposit disease and C3 GN.
L. Herlitz, A. Bomback, G. Markowitz, M. Stokes +4 more
2012Journal of the American Society of Nephrology158 citations Open access
Semantic Scholar
Early Change in Urine Protein as a Surrogate End Point in Studies of IgA Nephropathy: An Individual-Patient Meta-analysis.
L. Inker, Hasi Mondal, T. Greene, Taylor Masaschi +15 more
2016American Journal of Kidney Diseases150 citations Open access
Semantic Scholar
A meta-analysis of GFR slope as a surrogate endpoint for kidney failure
L. Inker, Willem H. Collier, Tom H. Greene, Shi-Yuan Miao +80 more
2023Nature Medicine146 citations Open access
Semantic Scholar
Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies
L. Mariani, S. Martini, L. Barisoni, P. Canetta +13 more
2018Nephrology, Dialysis and Transplantation115 citations Open access
Semantic Scholar
Randomized controlled trial of mycophenolate mofetil in children, adolescents, and adults with IgA nephropathy.
Ronald J. Hogg, R. Bay, J. Jennette, R. Sibley +12 more
2015American Journal of Kidney Diseases113 citations
Semantic Scholar
Treatment of idiopathic FSGS with adrenocorticotropic hormone gel.
J. Hogan, A. Bomback, Kshama Mehta, P. Canetta +4 more
2013American Society of Nephrology. Clinical Journal100 citations Open access
Semantic Scholar
Mycophenolate Mofetil in Combination with Steroids for Treatment of C3 Glomerulopathy: A Case Series.
Rupali S. Avasare, P. Canetta, A. Bomback, M. Marasà +5 more
2018American Society of Nephrology. Clinical Journal92 citations Open access
Semantic Scholar
Treatment of Resistant Glomerular Diseases with Adrenocorticotropic Hormone Gel: A Prospective Trial
A. Bomback, P. Canetta, L. Beck, R. Ayalon +2 more
2012American Journal of Nephrology92 citations
Semantic Scholar
Association of Treatment Effects on Early Change in Urine Protein and Treatment Effects on GFR Slope in IgA Nephropathy: An Individual Participant Meta-analysis
L. Inker, Hiddo J. Lambers-Heerspink, H. Tighiouart, Juhi Chaudhari +13 more
2021American Journal of Kidney Diseases89 citations
Semantic Scholar
Kidney Transplantation in C3 Glomerulopathy: A Case Series.
Renu Regunathan-Shenk, Rupali S. Avasare, Wooin Ahn, P. Canetta +3 more
2019American Journal of Kidney Diseases77 citations
Semantic Scholar
The relatively poor correlation between random and 24-hour urine protein excretion in patients with biopsy-proven glomerular diseases
Marie C. Hogan, H. Reich, Peter J. Nelson, S. Adler +6 more
2016Kidney International76 citations Open access
Semantic Scholar
Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis
L. Mariani, S. Eddy, Fadhl M. Alakwaa, P. McCown +62 more
2022Kidney International69 citations Open access
Semantic Scholar
Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies
C. Nester, G. Appel, A. Bomback, K. Bouman +17 more
2022American Journal of Nephrology66 citations Open access
Semantic Scholar
UBD modifies APOL1-induced kidney disease risk
Jia-Yue Zhang, Min-Xian Wang, Lei Tian, G. Genovese +10 more
2018Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
Semantic Scholar
Renal-limited 'lupus-like' nephritis.
A. Huerta, A. Bomback, V. Liakopoulos, A. Palanisamy +5 more
2012Nephrology, Dialysis and Transplantation56 citations Open access
Semantic Scholar
Contributions of Rare Gene Variants to Familial and Sporadic FSGS.
Min-Xian Wang, J. Chun, G. Genovese, Andrea U. Knob +7 more
2019Journal of the American Society of Nephrology55 citations Open access
Semantic Scholar
Complement-Mediated Glomerular Diseases: A Tale of 3 Pathways
A. Bomback, G. Markowitz, G. Appel
2016Kidney International Reports50 citations Open access
Semantic Scholar
Rituximab treatment for fibrillary glomerulonephritis.
J. Hogan, M. Restivo, P. Canetta, L. Herlitz +3 more
2014Nephrology, Dialysis and Transplantation49 citations Open access
Semantic Scholar
Effects of Bardoxolone Methyl in Alport Syndrome
B. Warady, P. Pergola, R. Agarwal, S. Andreoli +20 more
2021American Society of Nephrology. Clinical Journal46 citations Open access
Semantic Scholar
Study Design and Baseline Characteristics of the CARDINAL Trial: A Phase 3 Study of Bardoxolone Methyl in Patients with Alport Syndrome
G. Chertow, G. Appel, S. Andreoli, S. Bangalore +17 more
2021American Journal of Nephrology46 citations Open access
Semantic Scholar
Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy
S. Barbour, F. Fervenza, D. Induruwage, P. Brenchley +10 more
2023American Society of Nephrology. Clinical Journal45 citations Open access
Semantic Scholar
FSGS: Diagnosis and Diagnostic Work-Up
B. Sprangers, B. Meijers, G. Appel
2016BioMed Research International45 citations Open access
Semantic Scholar
Association of Histologic Parameters with Outcome in C3 Glomerulopathy and Idiopathic Immunoglobulin-Associated Membranoproliferative Glomerulonephritis
H. Lomax-Browne, Nicholas R. Medjeral-Thomas, S. Barbour, J. Gisby +21 more
2022American Society of Nephrology. Clinical Journal38 citations Open access
Semantic Scholar
Disaster Response to the COVID-19 Pandemic for Patients with Kidney Disease in New York City.
J. Radhakrishnan, A. Gharavi, S. Ahmad, Wooin Ahn +57 more
2020Journal of the American Society of Nephrology38 citations Open access
Semantic Scholar
Predicting Post-transplant Recurrence of IgA Nephropathy: The Importance of Crescents
Rupali S. Avasare, P. Rosenstiel, Z. S. Zaky, D. Tsapepas +4 more
2017American Journal of Nephrology38 citations Open access
Semantic Scholar
Anti-neutrophil cytoplasmic antibody associated glomerulonephritis complicating treatment with hydralazine.
D. Santoriello, A. Bomback, Satoru Kudose, I. Batal +6 more
2021Kidney International37 citations Open access
Semantic Scholar
Idiopathic Membranous Nephropathy: Clinical and Histologic Prognostic Features and Treatment Patterns over Time at a Tertiary Referral Center
B. Sprangers, A. Bomback, S. Cohen, J. Radhakrishnan +4 more
2012American Journal of Nephrology37 citations
Semantic Scholar
Glomerular diseases: emerging tests and therapies for IgA nephropathy.
P. Canetta, Krzysztof Kiryluk, G. Appel
2014American Society of Nephrology. Clinical Journal36 citations Open access
Semantic Scholar
Current therapy of granulomatosis with polyangiitis and microscopic polyangiitis: the role of rituximab
D. Geetha, C. Kallenberg, J. Stone, A. Salama +4 more
2014JN. Journal of Nephrology (Milano. 1992)34 citations Open access
Semantic Scholar
Impact of the ALMS and MAINTAIN trials on the management of lupus nephritis.
Heather K. Morris, P. Canetta, G. Appel
2013Nephrology, Dialysis and Transplantation31 citations Open access
Semantic Scholar
Change in Albuminuria and GFR Slope as Joint Surrogate End Points for Kidney Failure: Implications for Phase 2 Clinical Trials in CKD
H. Heerspink, L. Inker, H. Tighiouart, Willem H. Collier +20 more
2023Journal of the American Society of Nephrology25 citations Open access
Semantic Scholar
Baseline Clinical Characteristics and Complement Biomarkers of Patients with C3 Glomerulopathy Enrolled in Two Phase 2 Studies Investigating the Factor D Inhibitor Danicopan
S. Podos, H. Trachtman, G. Appel, A. Bomback +16 more
2022American Journal of Nephrology24 citations Open access
Semantic Scholar
Concurrent Anti-Glomerular Basement Antibody Disease and Membranous Nephropathy: A Case Series.
S. Ahmad, D. Santoriello, P. Canetta, A. Bomback +5 more
2021American Journal of Kidney Diseases24 citations
Semantic Scholar
How COVID-19 Has Changed the Management of Glomerular Diseases.
A. Bomback, P. Canetta, Wooin Ahn, S. Ahmad +2 more
2020American Society of Nephrology. Clinical Journal24 citations Open access
Semantic Scholar
Diagnostic tests and treatment options in glomerular disease: 2014 update.
J. Hogan, Prince Mohan, G. Appel
2014American Journal of Kidney Diseases23 citations
Semantic Scholar