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Shi-Dong Chen · SciRah

Researcher profile · Semantic Scholar

Shi-Dong Chen

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Shi-Dong Chen — researcher profile on SciRah

h-index: 30
Works: 101
Citations: 3,128

Most-cited papers

Atlas of the plasma proteome in health and disease in 53,026 adults.
Yue-Ting Deng, Jia You, Yu He, Yi Zhang +18 more
2024Cell271 citations Open access
Semantic Scholar
Post-Stroke Cognitive Impairment: Epidemiology, Risk Factors, and Management
Yu‐Yuan Huang, Shi-Dong Chen, Xin'yi Leng, Kevin Kuo +6 more
2022Journal of Alzheimer's Disease198 citations
Semantic Scholar
Retinal biomarkers in Alzheimer's disease and mild cognitive impairment: a systematic review and meta-analysis.
Yi-Jun Ge, Wei Xu, Ya‐nan Ou, Y. Qu +7 more
2021Ageing Research Reviews111 citations
Semantic Scholar
Sleep, physical activity, sedentary behavior, and risk of incident dementia: A prospective cohort study of 431,924 UK Biobank participants
Shue Huang, Yu-zhu Li, Ya-Ru Zhang, Yu‐Yuan Huang +14 more
2022Molecular Psychiatry107 citations
Semantic Scholar
Depression, Depression Treatments, and Risk of Incident Dementia: A Prospective Cohort Study of 354,313 Participants.
Liu Yang, Yue-Ting Deng, Y. Leng, Ya‐nan Ou +15 more
2022Biological Psychiatry102 citations
Semantic Scholar
Peripheral immunity is associated with the risk of incident dementia
Ya-Ru Zhang, Ji-Jing Wang, Shu-Fen Chen, Hui-Fu Wang +8 more
2022Molecular Psychiatry97 citations
Semantic Scholar
Modifiable risk factors for incident dementia and cognitive impairment: An umbrella review of evidence.
Ya-Ru Zhang, Wei Xu, Wei Zhang, Hui-Fu Wang +15 more
2021Journal of Affective Disorders97 citations Open access
Semantic Scholar
Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank
Yi Zhang, Shi-Dong Chen, Yue-Ting Deng, Jia You +11 more
2023Nature Human Behaviour95 citations
Semantic Scholar
Investigating Casual Associations Among Gut Microbiota, Metabolites, and Neurodegenerative Diseases: A Mendelian Randomization Study
Jin-Tai Yu, Jing Ning, Shue Huang, Shi-Dong Chen +2 more
2021Journal of Alzheimer's Disease88 citations Open access
Semantic Scholar
Plasma Glial Fibrillary Acidic Protein in the Alzheimer Disease Continuum: Relationship to Other Biomarkers, Differential Diagnosis, and Prediction of Clinical Progression.
Xue‐Ning Shen, Shue Huang, Mei Cui, Qianchuan Zhao +16 more
2023Clinical Chemistry86 citations Open access
Semantic Scholar
The dynamics of plasma biomarkers across the Alzheimer’s continuum
Yu Guo, Xue‐Ning Shen, Hui-Fu Wang, Shi-Dong Chen +7 more
2023Alzheimer's Research & Therapy82 citations Open access
Semantic Scholar
Plasma proteomics identify biomarkers and undulating changes of brain aging
Wei-Shi Liu, Jia You, Shi-Dong Chen, Yi Zhang +4 more
2024Nature Aging77 citations
Semantic Scholar
Associations of grip strength, walking pace, and the risk of incident dementia: A prospective cohort study of 340212 participants
Kevin Kuo, Ya-Ru Zhang, Shi-Dong Chen, Xiao-Yu He +12 more
2022Alzheimer's & Dementia76 citations
Semantic Scholar
Blood Biomarkers for the Diagnosis of Amnestic Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis.
Y. Qu, Ya-Hui Ma, Yu‐Yuan Huang, Ya‐nan Ou +5 more
2021Neuroscience and Biobehavioral Reviews74 citations
Semantic Scholar
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson's disease.
Kai-Min Wu, Qianhui Xu, Yiqi Liu, Yi Feng +25 more
2025Science70 citations
Semantic Scholar
Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study
Shi-Dong Chen, Jia-Ying Lu, Hong-Qi Li, Yu‐Xiang Yang +7 more
2021Translational Psychiatry67 citations Open access
Semantic Scholar
Herpesvirus infections and Alzheimer’s disease: a Mendelian randomization study
Shue Huang, Yu‐Xiang Yang, Kevin Kuo, Hong-Qi Li +6 more
2021Alzheimer's Research & Therapy67 citations Open access
Semantic Scholar
Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status
Xue‐Ning Shen, Yu‐Yuan Huang, Shi-Dong Chen, Yu Guo +4 more
2021Translational Psychiatry66 citations Open access
Semantic Scholar
Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer’s disease
Yu Guo, Shi-Dong Chen, Jia You, Shue Huang +11 more
2024Nature Human Behaviour61 citations
Semantic Scholar
Cortical structure and the risk for Alzheimer’s disease: a bidirectional Mendelian randomization study
Bang-Sheng Wu, Ya-Ru Zhang, Hong-Qi Li, Kevin Kuo +4 more
2021Translational Psychiatry60 citations Open access
Semantic Scholar
Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer’s disease
Shi-Dong Chen, Yu‐Yuan Huang, Xue‐Ning Shen, Yu Guo +3 more
2021Translational Psychiatry54 citations Open access
Semantic Scholar
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
Yi-Jun Ge, Ya‐nan Ou, Yue-Ting Deng, Bang-Sheng Wu +7 more
2022Biological Psychiatry47 citations Open access
Semantic Scholar
Association of biological age with health outcomes and its modifiable factors
Wei-Shi Liu, Jia You, Yi-Jun Ge, Bang-Sheng Wu +8 more
2023Aging Cell46 citations Open access
Semantic Scholar
Identifying causal genes for stroke via integrating the proteome and transcriptome from brain and blood
Bang-Sheng Wu, Shu-Fen Chen, Shue Huang, Ya‐nan Ou +4 more
2022Journal of Translational Medicine46 citations Open access
Semantic Scholar
Association of life course adiposity with risk of incident dementia: a prospective cohort study of 322,336 participants
Yue-Ting Deng, Yu-zhu Li, Shue Huang, Ya‐nan Ou +10 more
2022Molecular Psychiatry45 citations
Semantic Scholar
Cataract, Cataract Surgery, and Risk of Incident Dementia: A Prospective Cohort Study of 300,823 Participants.
Lingzhi Ma, Ya-Ru Zhang, Yu-zhu Li, Ya‐nan Ou +7 more
2022Biological Psychiatry43 citations
Semantic Scholar
Neurofilament light chain plasma concentration predicts neurodegeneration and clinical progression in nondemented elderly adults
Hao Hu, Keliang Chen, Ya‐nan Ou, Xi-Peng Cao +5 more
2019Aging43 citations Open access
Semantic Scholar
Lung function and risk of incident dementia: a prospective cohort study of 431,834 individuals.
Ya-Hui Ma, Lingjie Shen, Yu-zhu Li, Y. Leng +12 more
2023Brain, behavior, and immunity42 citations
Semantic Scholar
Characterization of Alzheimer’s tau biomarker discordance using plasma, CSF, and PET
Yu Guo, Yu‐Yuan Huang, Xue‐Ning Shen, Shi-Dong Chen +4 more
2021Alzheimer's Research & Therapy42 citations Open access
Semantic Scholar
Time spent in outdoor light is associated with the risk of dementia: a prospective cohort study of 362094 participants
Lingzhi Ma, Ya-Hui Ma, Ya‐nan Ou, Shi-Dong Chen +5 more
2022BMC Medicine41 citations Open access
Semantic Scholar
Mapping the plasma metabolome to human health and disease in 274,241 adults
Jia You, Xi-Han Cui, Yi-Lin Chen, Yi-Xuan Wang +16 more
2025Nature Metabolism30 citations Open access
Semantic Scholar
Association of circadian rhythms with brain disorder incidents: a prospective cohort study of 72242 participants
Si-Jie Chen, Yue-Ting Deng, Yu-zhu Li, Ya-Ru Zhang +8 more
2022Translational Psychiatry29 citations Open access
Semantic Scholar
Associations of resting heart rate with incident dementia, cognition, and brain structure: a prospective cohort study of UK biobank
Yue-Ting Deng, Kevin Kuo, Bang-Sheng Wu, Ya‐nan Ou +11 more
2022Alzheimer's Research & Therapy29 citations Open access
Semantic Scholar
Whole exome sequencing analyses identified novel genes for Alzheimer's disease and related dementia
Ya-Ru Zhang, Bang-Sheng Wu, Shi-Dong Chen, Liu Yang +8 more
2024Alzheimer's & Dementia26 citations Open access
Semantic Scholar
Genetically determined blood pressure, antihypertensive medications, and risk of Alzheimer’s disease: a Mendelian randomization study
Ya‐nan Ou, Yu‐Xiang Yang, Xue‐Ning Shen, Ya-Hui Ma +4 more
2020Alzheimer's Research & Therapy26 citations Open access
Semantic Scholar
Genome-wide association study unravels mechanisms of brain glymphatic activity
Shue Huang, Yi-Jun Ge, Peng Ren, Bang-Sheng Wu +16 more
2025Nature Communications23 citations Open access
Semantic Scholar
Large-scale proteomic analyses of incident Alzheimer’s disease reveal new pathophysiological insights and potential therapeutic targets
Yi Zhang, Yu Guo, Yu He, Jia You +12 more
2024Molecular Psychiatry23 citations
Semantic Scholar
Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
Yi-Jun Ge, Bang-Sheng Wu, Yi Zhang, Shi-Dong Chen +40 more
2023Nature Human Behaviour23 citations Open access
Semantic Scholar
Serum clinical laboratory tests and risk of incident dementia: a prospective cohort study of 407,190 individuals
Xiao-Yu He, Kevin Kuo, Liu Yang, Ya-Ru Zhang +5 more
2022Translational Psychiatry22 citations Open access
Semantic Scholar
Life Course Adiposity and Alzheimer’s Disease: A Mendelian Randomization Study
Xian Li, Yan Tian, Yu‐Xiang Yang, Ya-Hui Ma +5 more
2021Journal of Alzheimer's Disease22 citations
Semantic Scholar
Exome sequencing identifies genes associated with sleep-related traits
Chen-Jie Fei, Ze-Yu Li, Jing Ning, Liu Yang +11 more
2024Nature Human Behaviour21 citations
Semantic Scholar
Modified dementia risk score as a tool for the prediction of dementia: a prospective cohort study of 239745 participants
Zuo-Teng Wang, Yan Fu, Ya-Ru Zhang, Shi-Dong Chen +10 more
2022Translational Psychiatry21 citations Open access
Semantic Scholar
Differences between ante mortem Alzheimer's disease biomarkers in predicting neuropathology at autopsy
Zhi-Bo Wang, L. Tan, Hui-Fu Wang, Shi-Dong Chen +7 more
2023Alzheimer's & Dementia19 citations
Semantic Scholar
Investigating causal relationships between exposome and human longevity: a Mendelian randomization analysis
Shue Huang, Yu‐Xiang Yang, Shi-Dong Chen, Hong-Qi Li +7 more
2020BMC Medicine19 citations Open access
Semantic Scholar
Social Isolation, Social Interaction, and Alzheimer’s Disease: A Mendelian Randomization Study
Lingjie Shen, Yu‐Xiang Yang, Kevin Kuo, Hong-Qi Li +5 more
2021Journal of Alzheimer's Disease18 citations
Semantic Scholar
Poor Oral Health and Risk of Incident Dementia: A Prospective Cohort Study of 425,183 Participants
Rui-Qi Zhang, Ya‐nan Ou, Shue Huang, Yu-zhu Li +7 more
2023Journal of Alzheimer's Disease16 citations
Semantic Scholar
A Novel ITM2B Mutation Associated with Familial Chinese Dementia
Xin Liu, Keliang Chen, Yi Wang, Yu‐Yuan Huang +4 more
2021Journal of Alzheimer's Disease16 citations
Semantic Scholar
Machine learning-assisted optimization of dietary intervention against dementia risk
Si-Jia Chen, Hui Chen, Jia You, Shi-Dong Chen +8 more
2025Nature Human Behaviour15 citations
Semantic Scholar
The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders
Shi-Dong Chen, Jia You, Wei Zhang, Bang-Sheng Wu +34 more
2024Nature Human Behaviour15 citations Open access
Semantic Scholar
Circulating metabolites associated with incident myocardial infarction and stroke: A prospective cohort study of 90 438 participants
Yu Guo, Shu-Fen Chen, Ya-Ru Zhang, Hui-Fu Wang +10 more
2022Journal of Neurochemistry15 citations
Semantic Scholar

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Jin-Tai Yu×50
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Jin-Tai Yu — researcher profile on SciRah
Ya-Ru Zhang×28
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Ya-Ru Zhang — researcher profile on SciRah
W. Cheng×25
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L. Tan×24
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Bang-Sheng Wu×18

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Ya‐nan Ou×17

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Ya‐nan Ou — researcher profile on SciRah

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Shue Huang — researcher profile on SciRah

Qiang-Li Dong×16

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Qiang-Li Dong — researcher profile on SciRah

Jian-Feng Feng×16

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Yue-Ting Deng×15

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Yue-Ting Deng — researcher profile on SciRah

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Yu Guo — researcher profile on SciRah